C. Flentge

发表

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.

A. Molla, S. Vasavanonda, D. Norbeck, 1998, Journal of medicinal chemistry.

Fluorescence polarization immunoassay of urinary 5-hydroxy-3-indoleacetic acid.

L. Janulis, D. Betebenner, C. Flentge, 1989, Clinical chemistry.

Evaluation of substituted benzamides as P2 ligands for symmetry-based inhibitors of HIV protease

S. Vasavanonda, D. Norbeck, D. Kempf, 1995 .

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif.

K. Longenecker, A. C. Krueger, A. Molla, 2013, Bioorganic & medicinal chemistry letters.

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.

A. Molla, D. Kempf, H. Mo, 2006, Bioorganic & Medicinal Chemistry.

Identification of aryl dihydrouracil derivatives as palm initiation site inhibitors of HCV NS5B polymerase.

A. Molla, J. Randolph, C. Flentge, 2012, Bioorganic & medicinal chemistry letters.

955 PRECLINICAL POTENCY, PHARMACOKINETIC AND ADME CHARACTERIZATION OF ABT-333, A NOVEL NON-NUCLEOSIDE HCV POLYMERASE INHIBITOR

A. Molla, D. Beno, C. Flentge, 2009 .

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

S. Vasavanonda, D. Norbeck, D. Kempf, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Hepatitis C NS5B polymerase inhibitors: functional equivalents for the benzothiadiazine moiety.

V. Stoll, A. Molla, D. Kempf, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors.

A. Molla, D. Kempf, J. Randolph, 2009, Journal of medicinal chemistry.

Oximinoarylsulfonamides as potent HIV protease inhibitors.

V. Stoll, D. Kempf, J. Randolph, 2005, Bioorganic & medicinal chemistry letters.

Decomposition of solid peroxydisulfates

J. E. House, C. Flentge, 1978 .

Lack of stereospecificity in the binding of the P2 amino acid of ritonavir to HIV protease

A. D. Rodrigues, S. Muchmore, A. Molla, 1997 .

Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530).

A. C. Krueger, T. Pilot‐Matias, J. Randolph, 2018, Journal of medicinal chemistry.

2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.

V. Stoll, A. Molla, D. Kempf, 2009, Journal of medicinal chemistry.

Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs.

D. Kempf, J. Randolph, K. Marsh, 2009, Bioorganic & medicinal chemistry letters.

Discovery of fluorobenzimidazole HCV NS5A inhibitors.

T. Pilot‐Matias, J. Randolph, D. Beno, 2016, Bioorganic & medicinal chemistry letters.