J. Patterson

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.

A. Molla, S. Vasavanonda, D. Norbeck, 1998, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.

James R. Porter, J. Sydor, J. Adams, 2006, Journal of medicinal chemistry.

Update on Phase I Clinical Trial of IPI-504, a Novel, Water-Soluble Hsp90 Inhibitor, in Patients with Relapsed/Refractory Multiple Myeloma (MM).

S. Jagannath, J. Sydor, P. Richardson, 2005 .

Anti-Tumor Activity of IPI-504, a Novel Hsp90 Inhibitor in Multiple Myeloma.

J. Sydor, M. Foley, C. Mitsiades, 2004 .

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90

Jie Ge, James R. Porter, J. Sydor, 2006, Proceedings of the National Academy of Sciences.

IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells

V. Palombella, C. Fritz, J. Patterson, 2008, Cancer Chemotherapy and Pharmacology.