C. Posthuma

发表

Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes

Christian Drosten, Xavier Morelli, Stéphane Betzi, 2014, The Journal of Biological Chemistry.

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

T. Bestebroer, J. Neyts, E. Snijder, 2014, Antimicrobial Agents and Chemotherapy.

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly 3 inhibited by cyclosporin A or interferon-alpha treatment 4 5 6

T. Bestebroer, B. Haagmans, V. S. Raj, 2013 .

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

T. Bestebroer, M. Bárcena, B. Haagmans, 2013, The Journal of general virology.

Formation of the Arterivirus Replication/Transcription Complex: a Key Role for Nonstructural Protein 3 in the Remodeling of Intracellular Membranes

Zhengchun Lu, R. G. Joosten, K. Pedersen, 2008, Journal of Virology.

CultureCoronavirus Replication in Cell Inhibitors of Middle East Respiratory Library Identifies Four Small-Molecule Screening of an FDA-Approved Compound

T. Bestebroer, E. Snijder, D. Jochmans, 2014 .

An infectious recombinant equine arteritis virus expressing green fluorescent protein from its replicase gene.

K. Knoops, E. Snijder, C. Posthuma, 2007, The Journal of general virology.

6′,6′-Difluoro-aristeromycin is a potent inhibitor of MERS-coronavirus replication

Natacha S. Ogando, L. Jeong, S. Tripathi, 2021, bioRxiv.

Cloning, Sequence Analysis, and Characterization of the Genes Involved in Isoprimeverose Metabolism in Lactobacillus pentosus

P. Postma, P. Pouwels, R. Leer, 1998, Journal of bacteriology.

Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

H. Feldmann, S. Perlman, D. Falzarano, 2016, Virus Research.

Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity

J. Neyts, E. Snijder, D. Jochmans, 2015, Bioorganic & Medicinal Chemistry Letters.

What we know but do not understand about nidovirus helicases

A. Gorbalenya, E. Snijder, C. Posthuma, 2014, Virus Research.

Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors

M. Bárcena, E. Snijder, C. Posthuma, 2019, Journal of Virology.

Inhibition of arterivirus RNA synthesis by cyclophilin inhibitors is counteracted by mutations in replicase transmembrane subunits

M. Bárcena, E. Snijder, C. Posthuma, 2019, bioRxiv.

Site-Directed Mutagenesis of the Nidovirus Replicative Endoribonuclease NendoU Exerts Pleiotropic Effects on the Arterivirus Life Cycle

A. Gorbalenya, E. Snijder, C. Posthuma, 2006, Journal of Virology.

Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision

A. Koster, T. Sharp, M. Bárcena, 2017, Scientific Reports.

Structure and Genetic Analysis of the Arterivirus Nonstructural Protein 7α

P. Tucker, I. Manolaridis, B. Canard, 2011, Journal of Virology.

Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues

Natacha S. Ogando, L. Jeong, M. V. van Hemert, 2019, Journal of medicinal chemistry.

Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus.

E. Claas, E. Snijder, W. Spaan, 2011, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2

Natacha S. Ogando, Y. van der Meer, E. Snijder, 2020, Journal of Virology.

Expression of the Xylulose 5-Phosphate Phosphoketolase Gene, xpkA, from Lactobacillus pentosus MD363 Is Induced by Sugars That Are Fermented via the Phosphoketolase Pathway and Is Repressed by Glucose Mediated by CcpA and the Mannose Phosphoenolpyruvate Phosphotransferase System

Wolfgang Hengstenberg, Pieter W. Postma, P. Postma, 2002, Applied and Environmental Microbiology.

Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production

J. F. Atkins, A. Firth, N. Wills, 2011, The Journal of general virology.

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

E. Decroly, A. Gorbalenya, B. Canard, 2014, Proceedings of the National Academy of Sciences.

The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle

J. Drijfhout, M. Raaben, P. Rottier, 2010, Journal of Virology.

Cyclophilins and cyclophilin inhibitors in nidovirus replication

E. Snijder, C. Posthuma, Adriaan H. de Wilde, 2018, Virology.

Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes

E. Snijder, C. Posthuma, A. J. T. te Velthuis, 2017, Virus Research.

Mass Spectrometry-Based Comparative Sequence Analysis for the Genetic Monitoring of Influenza A(H1N1)pdm09 Virus

E. Claas, C. Posthuma, Jessika C. Zevenhoven-Dobbe, 2014, PloS one.

The enzymatic activity of the nsp14 exoribonuclease is critical for replication of Middle East respiratory syndrome-coronavirus

Natacha S. Ogando, E. Snijder, C. Posthuma, 2020, bioRxiv.

The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

Natacha S. Ogando, E. Decroly, B. Canard, 2019, Front. Microbiol..

Proton motive force generation by citrolactic fermentation in Leuconostoc mesenteroides

W. Konings, P. Schmitt, C. Diviès, 1996, Journal of bacteriology.

Arterivirus RNA-dependent RNA polymerase: Vital enzymatic activity remains elusive

A. Gorbalenya, E. Snijder, C. Posthuma, 2015, Virology.

Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase

Alexander E. Gorbalenya, Lin Yu, Eric J. Snijder, 2013, Nucleic acids research.

Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture

P. Gallay, D. de Jong, E. Snijder, 2017, Virology.

A Complex Zinc Finger Controls the Enzymatic Activities of Nidovirus Helicases

J. Ziebuhr, A. Gorbalenya, E. Snijder, 2005, Journal of Virology.

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses

A. M. Leontovich, A. Gorbalenya, I. Sidorov, 2015, Nucleic acids research.

Discontinuous Subgenomic RNA Synthesis in Arteriviruses Is Guided by an RNA Hairpin Structure Located in the Genomic Leader Region

A. Gultyaev, E. Snijder, C. Posthuma, 2005, Journal of Virology.

Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role in Betacoronavirus replication

E. Decroly, B. Canard, V. Thiel, 2021, Proceedings of the National Academy of Sciences.

Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision

A. Koster, T. Sharp, M. Bárcena, 2017, Scientific Reports.

Formation of the Arterivirus Replication/Transcription Complex: a Key Role for Nonstructural Protein 3 in the Remodeling of Intracellular Membranes

Zhengchun Lu, K. Pedersen, E. Snijder, 2008, Journal of Virology.