Taj Mohammad

发表

Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy

Asimul Islam, Md. Imtaiyaz Hassan, Taj Mohammad, 2020, Bioscience reports.

Structure, function and therapeutic implications of OB-fold proteins: A lesson from past to present.

F. Ahmad, A. Islam, Mohd. Amir, 2020, Briefings in functional genomics.

Identification of High-Affinity Inhibitors of Cyclin-Dependent Kinase 2 Towards Anticancer Therapy

Rashmi Dahiya, I. Rather, Mohd Hassan Baig, 2019, Molecules.

Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy

Abdullah M. Asiri, Suaib Luqman, M. I. Hassan, 2020, Biomedicines.

Differential gene expression and network analysis in head and neck squamous cell carcinoma

M. I. Hassan, F. Anjum, D. Yadav, 2022, Molecular and Cellular Biochemistry.

Bioactive phytoconstituents as potent inhibitors of casein kinase-2: dual implications in cancer and COVID-19 therapeutics

M. I. Hassan, G. Ashraf, F. Alhumaydhi, 2022, RSC advances.

Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer

M. I. Hassan, Prithvi Singh, L. A. Al-keridis, 2022, Frontiers in Oncology.

Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy

M. I. Hassan, A. Islam, A. Hussain, 2020, Virus Research.

Investigation of conformational dynamics of Tyr89Cys mutation in protection of telomeres 1 gene associated with familial melanoma

F. Ahmad, M. I. Hassan, A. Islam, 2019, Journal of biomolecular structure & dynamics.

Identification of high-affinity inhibitors of pyruvate dehydrogenase kinase-3: towards therapeutic management of cancer

M. I. Hassan, A. Islam, A. Hussain, 2020, Journal of biomolecular structure & dynamics.

Biophysical Insights into Implications of PEG-400 on the α-Crystallin Structure: Multispectroscopic and Microscopic Approach

F. Ahmad, M. I. Hassan, A. Islam, 2020, ACS omega.

Comparative analysis of web-based programs for single amino acid substitutions in proteins

Visweswara Rao Pasupuleti, M. I. Hassan, I. K. Singh, 2022, PloS one.

Exploring molecular insights into the interaction mechanism of cholesterol derivatives with the Mce4A: A combined spectroscopic and molecular dynamic simulation studies.

Faez Iqbal Khan, F. Ahmad, K. Lobb, 2018, International journal of biological macromolecules.

Mechanistic insights into the role of serum-glucocorticoid kinase 1 in diabetic nephropathy: A systematic review.

M. I. Hassan, D. Yadav, A. L. Bilgrami, 2021, International journal of biological macromolecules.

Vitamin D and lumisterol novel metabolites can inhibit SARS-CoV-2 replication machinery enzymes

M. I. Hassan, A. Slominski, C. Raman, 2021, American journal of physiology. Endocrinology and metabolism.

Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome

F. Ahmad, Vijay Kumar, M. I. Hassan, 2019, Front. Mol. Biosci..

Impact of amino acid substitution in the kinase domain of Bruton tyrosine kinase and its association with X-linked agammaglobulinemia.

Vijay Kumar, M. I. Hassan, A. Hussain, 2020, International journal of biological macromolecules.

MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy

M. I. Hassan, A. Islam, A. Hussain, 2020, Biomolecules.

Discovering Tuberosin and Villosol as Potent and Selective Inhibitors of AKT1 for Therapeutic Targeting of Oral Squamous Cell Carcinoma

M. I. Hassan, A. Elasbali, D. Yadav, 2022, Journal of personalized medicine.

A multi-spectroscopic and computational simulations study to delineate the interaction between antimalarial drug hydroxychloroquine and human serum albumin

M. I. Hassan, Anas Shamsi, Rajan Patel, 2022, Journal of biomolecular structure & dynamics.

Identification and structure-activity relationship (SAR) studies of carvacrol derivatives as potential anti-malarial against Plasmodium falciparum falcipain-2 protease.

Taj Mohammad, Shailja Singh, Vigyasa Singh, 2020, Bioorganic chemistry.

Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies

Faez Iqbal Khan, M. I. Hassan, Dongming Lan, 2019, International journal of molecular sciences.

Fructosylation of human insulin causes AGEs formation, structural perturbations and morphological changes: an in silico and multispectroscopic study

Asif Ali, Md. Amiruddin Hashmi, Taj Mohammad, 2022, Journal of biomolecular structure & dynamics.

Implication of Synthetic Biology in Biotherapeutic Engineering

M. I. Hassan, Rashmi Dahiya, Taj Mohammad, 2020 .

A computational study on active constituents of Habb-ul-aas and Tabasheer as inhibitors of SARS-CoV-2 main protease

A. Islam, Mohd. Shahbaaz, F. Husain, 2021, Journal of biomolecular structure & dynamics.

Inhibiting Cyclin-Dependent Kinase 6 by Taurine: Implications in Anticancer Therapeutics

M. I. Hassan, A. Islam, Naved Azum, 2022, ACS omega.

Cinnamomum zeylanicum Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects via Inhibition of Multiple Cellular Pathways

M. I. Hassan, Satya N. Das, L. A. Al-keridis, 2022, Frontiers in Pharmacology.

Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy

M. I. Hassan, A. Hussain, M. Alajmi, 2020, ACS omega.

Identifying Isoononin and Candidissiol as Rho-associated protein kinase 1 (ROCK1) inhibitors: a combined virtual screening and MD simulation approach

M. I. Hassan, F. Alhumaydhi, A. Elasbali, 2022, Journal of biomolecular structure & dynamics.

Searching for Novel Anaplastic Lymphoma Kinase Inhibitors: Structure-Guided Screening of Natural Compounds for a Tyrosine Kinase Therapeutic Target in Cancers.

F. Bardakci, A. Elasbali, Taj Mohammad, 2022, Omics : a journal of integrative biology.

A virtual screening investigation to identify bioactive natural compounds as potential inhibitors of cyclin-dependent kinase 9

G. Ashraf, F. Alhumaydhi, Sharaf E Sharaf, 2022, Journal of biomolecular structure & dynamics.

Identification of plant-based hexokinase 2 inhibitors: combined molecular docking and dynamics simulation studies

S. Husain, A. Hussain, M. Alajmi, 2021, Journal of biomolecular structure & dynamics.

Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies

F. Ahmad, A. Islam, A. Hussain, 2020, Molecules.

Aurora B kinase: a potential drug target for cancer therapy

A. Islam, Anas Shamsi, Taj Mohammad, 2021, Journal of Cancer Research and Clinical Oncology.

Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders

F. Ahmad, A. Islam, Mohd. Shahbaaz, 2020, Oxidative medicine and cellular longevity.

Probing the interaction of Rivastigmine Tartrate, an important Alzheimer's drug, with serum albumin: Attempting treatment of Alzheimer's disease.

F. Ahmad, A. Islam, A. Hussain, 2020, International journal of biological macromolecules.

Advancements in Docking and Molecular Dynamics Simulations Towards Ligand-receptor Interactions and Structure-function Relationships.

Ahmad Abu Turab Naqvi, Taj Mohammad, Gulam Mustafa Hasan, 2018, Current topics in medicinal chemistry.

Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations

F. Anjum, D. Yadav, Alaa Shafie, 2021, Pharmaceutics.

Biomedical features and therapeutic potential of rosmarinic acid

Malik Abdul Rub, Naved Azum, D. Yadav, 2022, Archives of Pharmacal Research.

Thymoquinone and quercetin induce enhanced apoptosis in non‐small cell lung cancer in combination through the Bax/Bcl2 cascade

Taj Mohammad, M. Husain, Rayees Padder, 2021, Journal of cellular biochemistry.

Discovery of Novel Drug Targets in Microbial Pathogens Among Hypothetical Proteins: Methods and Significance

Taj Mohammad, A. Naqvi, M. Hassan, 2019, Pathogenicity and Drug Resistance of Human Pathogens.

Insight into the binding of PEG-400 with eye protein alpha-crystallin: Multi spectroscopic and computational approach: possible therapeutics targeting eye diseases

F. Ahmad, A. Islam, Anas Shamsi, 2020, Journal of biomolecular structure & dynamics.

InstaDock: A single-click graphical user interface for molecular docking-based virtual high-throughput screening

Taj Mohammad, Md Imtaiyaz Hassan, Yash Mathur, 2020, Briefings Bioinform..

Potential drug targets of SARS-CoV-2: From genomics to therapeutics

A. Islam, F. Husain, Anas Shamsi, 2021, International Journal of Biological Macromolecules.

Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.

A. Islam, Anas Shamsi, Taj Mohammad, 2021, Biochimica et biophysica acta. Reviews on cancer.

Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases

F. Ahmad, A. Islam, F. Husain, 2019, Biomolecules.

Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

Md. Imtaiyaz Hassan, Ahmad Abu Turab Naqvi, Taj Mohammad, 2020, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

Discovery of Harmaline as a Potent Inhibitor of Sphingosine Kinase-1: A Chemopreventive Role in Lung Cancer

Suaib Luqman, Rashmi Dahiya, Preeti Gupta, 2020, ACS omega.

Design and Development of Novel Urea, Sulfonyltriurea, and Sulfonamide Derivatives as Potential Inhibitors of Sphingosine Kinase 1

A. Hussain, M. Alajmi, Preeti Gupta, 2020, Pharmaceuticals.

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

A. Islam, F. Anjum, D. Yadav, 2021, PloS one.

Unravelling hub genes as potential therapeutic targets in lung cancer using integrated transcriptomic meta-analysis and in silico approach

Prithvi Singh, Aiman Mushtaq, M. Syed, 2022, Journal of biomolecular structure & dynamics.

Role of Genome-Wide Association Studies in Host Genetics: Toward Understanding of Microbiome Association

Rashmi Dahiya, Taj Mohammad, M. Hassan, 2020 .

Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging

A. Hussain, M. Alajmi, Rashmi Dahiya, 2020, Biomolecules.

Genome Engineering Tools in Immunotherapy

Rashmi Dahiya, Taj Mohammad, M. Hassan, 2020 .

Investigating the structural features of chromodomain proteins in the human genome and predictive impacts of their mutations in cancers.

A. Hussain, M. Alajmi, Rashmi Dahiya, 2019, International journal of biological macromolecules.

Impact of Deleterious Mutations on Structure, Function and Stability of Serum/Glucocorticoid Regulated Kinase 1: A Gene to Diseases Correlation

A. Hussain, M. Alajmi, P. Hansbro, 2021, Frontiers in Molecular Biosciences.

Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy.

A. Hussain, M. Alajmi, Preeti Gupta, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Therapeutic Potential of Polyphenols in Alzheimer’s Therapy: Broad-Spectrum and Minimal Side Effects as Key Aspects

A. Islam, M. Shahwan, Anas Shamsi, 2021, Autism Spectrum Disorder and Alzheimer's Disease.

β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development

P. Pajukanta, M. Allison, M. Vacca, 2021, Science Translational Medicine.

Genomic Variations in the Structural Proteins of SARS-CoV-2 and Their Deleterious Impact on Pathogenesis: A Comparative Genomics Approach

F. Anjum, D. Yadav, Alaa Shafie, 2021, Frontiers in Cellular and Infection Microbiology.

FNDC5/Irisin: Physiology and Pathophysiology

F. Ahmad, A. Islam, Anas Shamsi, 2022, Molecules.

B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy

D. Yadav, Taj Mohammad, G. Hasan, 2021, International journal of molecular sciences.

Modern Approaches in Synthetic Biology: Genome Editing, Quorum Sensing, and Microbiome Engineering

Taj Mohammad, M. Hassan, 2018 .

Therapeutic targeting of TANK-binding kinase signaling towards anticancer drug development: Challenges and opportunities.

Taj Mohammad, Md Meraj Ansari, S. Noor, 2022, International journal of biological macromolecules.

Impact of single amino acid substitution on the structure and function of TANK‐binding kinase‐1

A. Islam, F. Anjum, Alaa Shafie, 2021, Journal of cellular biochemistry.

Investigation of deleterious effects of nsSNPs in the POT1 gene: a structural genomics‐based approach to understand the mechanism of cancer development

F. Ahmad, Vijay Kumar, A. Islam, 2018, Journal of cellular biochemistry.

Impact of non-synonymous mutations on the structure and function of telomeric repeat binding factor 1

A. Hussain, M. Alajmi, F. Anjum, 2021, Journal of biomolecular structure & dynamics.

Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma

F. Ahmad, Vijay Kumar, A. Islam, 2020, Journal of biomolecular structure & dynamics.

Mutated CEACAMs Disrupt Transforming Growth Factor beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis.

K. Crandall, H. Noushmehr, R. Mazumder, 2019, Gastroenterology.

Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach

F. Ahmad, Vijay Kumar, A. Hussain, 2018, bioRxiv.

Identification and evaluation of glutathione conjugate gamma-l-glutamyl-l-cysteine for improved drug delivery to the brain

A. Hussain, F. Ahmad, M. Alajmi, 2020, Journal of biomolecular structure & dynamics.

Molecular interaction studies on ellagic acid for its anticancer potential targeting pyruvate dehydrogenase kinase 3

A. Hussain, M. Alajmi, Rashmi Dahiya, 2019, RSC advances.

Desmodin and isopongachromene as potential inhibitors of cyclin-dependent kinase 5: phytoconstituents targeting anticancer and neurological therapy

G. Ashraf, F. Alhumaydhi, Saleh Baeesa, 2022, Journal of biomolecular structure & dynamics.

Phytoconstituents and Medicinal Plants for Anticancer Drug Discovery: Computational Identification of Potent Inhibitors of PIM1 Kinase.

F. Anjum, Taj Mohammad, Abdulraheem A Almalki, 2021, Omics : a journal of integrative biology.

Discovery of Natural Compounds as Potential Inhibitors of Human Carbonic Anhydrase II: An Integrated Virtual Screening, Docking, and Molecular Dynamics Simulation Study.

F. Anjum, Alaa Shafie, Taj Mohammad, 2021, Omics : a journal of integrative biology.

Targeting metacaspase-3 from Plasmodium falciparum towards antimalarial therapy: A combined approach of in-silico and in-vitro investigation

F. Ahmad, A. Islam, A. Hussain, 2020, Journal of biomolecular structure & dynamics.

Identification and evaluation of bioactive natural products as potential inhibitors of human microtubule affinity-regulating kinase 4 (MARK4)

Asimul Islam, Faizan Ahmad, Taj Mohammad, 2019, Journal of biomolecular structure & dynamics.

Evaluation of binding and inhibition mechanism of dietary phytochemicals with sphingosine kinase 1: Towards targeted anticancer therapy

A. Hussain, M. Alajmi, Rashmi Dahiya, 2019, Scientific Reports.

Iron response elements (IREs)-mRNA of Alzheimer's amyloid precursor protein binding to iron regulatory protein (IRP1): a combined molecular docking and spectroscopic approach

Mateen A. Khan, Taj Mohammad, Ajamaluddin Malik, 2023, Scientific Reports.

Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson’s Disease

Visweswara Rao Pasupuleti, F. Alhumaydhi, M. Shahwan, 2022, Journal of personalized medicine.

Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

Shailza Singh, A. Islam, A. Hussain, 2021, Scientific Reports.

Discovering potential inhibitors of Raf proto-oncogene serine/threonine kinase 1: a virtual screening approach towards anticancer drug development.

W. Al-Soud, Taj Mohammad, Shama Khan, 2023, Journal of biomolecular structure & dynamics.

Integrated virtual screening and MD simulation study to discover potential inhibitors of Lyn-kinase: targeting cancer therapy

M. Shahwan, Anas Shamsi, Taj Mohammad, 2022, Journal of biomolecular structure & dynamics.

Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy.

F. Ahmad, A. Islam, Rashmi Dahiya, 2019, International journal of biological macromolecules.

Identification of α-Mangostin as a Potential Inhibitor of Microtubule Affinity Regulating Kinase 4.

Taj Mohammad, Sher Ali, Parvez Khan, 2019, Journal of natural products.

Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression.

Faez Iqbal Khan, F. Ahmad, Suaib Luqman, 2018, International journal of biological macromolecules.

Identification of intrinsically disorder regions in non-structural proteins of SARS-CoV-2: New insights into drug and vaccine resistance

Shailza Singh, V. Uversky, F. Anjum, 2022, Molecular and Cellular Biochemistry.

Target-Based Virtual Screening of Natural Compounds Identifies a Potent Antimalarial With Selective Falcipain-2 Inhibitory Activity

A. Hussain, H. El‐Seedi, M. Alajmi, 2022, Frontiers in Pharmacology.

Virtual high-throughput screening of natural compounds in-search of potential inhibitors for protection of telomeres 1 (POT1)

F. Ahmad, A. Islam, Taj Mohammad, 2020, Journal of biomolecular structure & dynamics.

Identification of natural product-based effective inhibitors of spleen tyrosine kinase (SYK) through virtual screening and molecular dynamics simulation approaches.

F. Anjum, Alaa Shafie, Taj Mohammad, 2023, Journal of biomolecular structure & dynamics.

Investigating MARK4 inhibitory potential of Bacopaside II: Targeting Alzheimer's disease.

P. Kaur, A. Islam, Taj Mohammad, 2023, International journal of biological macromolecules.

Identification of novel c-Kit inhibitors from natural sources using virtual screening and molecular dynamics simulations.

W. Al-Soud, A. Elasbali, Taj Mohammad, 2023, Journal of biomolecular structure & dynamics.

Structure-based identification of potential inhibitors of ribosomal protein S6 kinase 1, targeting cancer therapy: a combined docking and molecular dynamics simulations approach

A. Nadeem, Taj Mohammad, Md Nayab Sulaimani, 2023, Journal of biomolecular structure & dynamics.

Identification of natural compounds as potent inhibitors of SARS-CoV-2 main protease using combined docking and molecular dynamics simulations

A. Hussain, M. Alajmi, F. Anjum, 2021, Saudi Journal of Biological Sciences.

Genome Microbiology for Synthetic Applications

Taj Mohammad, M. Hassan, 2018 .

An integrated docking and molecular dynamics simulation approach to discover potential inhibitors of activin receptor-like kinase 1.

M. Alajmi, Taj Mohammad, D. Jairajpuri, 2023, Journal of molecular recognition : JMR.

Identifying potential inhibitors of phosphatidylinositol 4,5-bisphosphate 3-kinase: Molecular dynamic insights into the interaction and inhibitory mechanism

M. Alajmi, Taj Mohammad, M. Hassan, 2024, Chemical Physics Impact.

Death-Associated Protein Kinase 3 Inhibitors Identified by Virtual Screening for Drug Discovery in Cancer and Hypertension.

F. Alhumaydhi, A. Elasbali, Taj Mohammad, 2022, Omics : a journal of integrative biology.

Discovering novel inhibitors of RfaH from Klebsiella pneumoniae to combat antimicrobial resistance.

M. Alajmi, Taj Mohammad, A. Choudhury, 2024, Archives of microbiology.