Q. Q. Hoang

发表

Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.

Gregory A Petsko, Dagmar Ringe, Chittaranjan Das, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus.

G. Petsko, D. Ringe, A. Milne, 2008, Biochemistry.

A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson’s disease

G. Petsko, M. Emre, H. Hanagasi, 2021, Parkinsonism & related disorders.

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.

K. Tsumoto, Makoto Nakakido, S. Nagatoishi, 2018, ACS chemical biology.

Thermodynamic and structural characterization of the specific binding of Zn(II) to human protein DJ-1.

K. Tsumoto, J. Caaveiro, Q. Q. Hoang, 2014, Biochemistry.

Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein

W. Im, M. Oh, C. Burlak, 2014, Proceedings of the National Academy of Sciences.

Roc, the G-domain of the Parkinson's disease-associated protein LRRK2.

Q. Q. Hoang, Yangshin Park, J. Liao, 2022, Trends in biochemical sciences.

Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics

Steven M. Johnson, M. Cookson, R. Nichols, 2019, The Journal of Biological Chemistry.

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT

Wei Wang, Thomas C. Terwilliger, Dagmar Ringe, 2013, Proceedings of the National Academy of Sciences.

Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens.

G. Petsko, D. Ringe, W. Fast, 2007, Biochemistry.

A soluble α-synuclein construct forms a dynamic tetramer

Wei Wang, Gregory A Petsko, Dagmar Ringe, 2011, Proceedings of the National Academy of Sciences.

Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

Steven M. Johnson, E. Chapman, Q. Q. Hoang, 2021, mBio.

Longitudinal IgG antibody responses to Plasmodium vivax blood-stage antigens during and after acute vivax malaria in individuals living in the Brazilian Amazon

J. Rayner, R. Longley, W. Tham, 2022, medRxiv.

Bone recognition mechanism of porcine osteocalcin from crystal structure

Quyen Q. Hoang, A. Howard, F. Sicheri, 2003, Nature.

Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA).

Steven M. Johnson, P. Schultz, A. Horwich, 2018, Journal of medicinal chemistry.

Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites

G. Petsko, D. Ringe, J. Dekker, 2016, Proceedings of the National Academy of Sciences.

Roco Proteins and the Parkinson’s Disease-Associated LRRK2

Q. Q. Hoang, J. Liao, 2018, International journal of molecular sciences.

Hydrophilic Residues Are Crucial for Ribosomal Protein L11 (RPL11) Interaction with Zinc Finger Domain of MDM2 and p53 Protein Activation*

Hua Lu, Qi Zhang, S. Chai, 2011, The Journal of Biological Chemistry.

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

Dima Kozakov, Ryan Brenke, Dmitri Beglov, 2009, J. Comput. Aided Mol. Des..

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

G. Petsko, E. Bézard, D. Ringe, 2016, Proceedings of the National Academy of Sciences.

Allosteric differences dictate GroEL complementation of E. coli

Steven M. Johnson, G. Lander, Donna D. Zhang, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs.

Steven M. Johnson, E. Chapman, Q. Q. Hoang, 2020, Bioorganic & medicinal chemistry.

Xenotransplantation literature update, May–June 2014

C. Burlak, Q. Q. Hoang, 2014, Xenotransplantation.

Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domain

Todd A. Stone, Shenmin Zhang, M. Cookson, 2014, Proceedings of the National Academy of Sciences.

HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.

Steven M. Johnson, E. Chapman, Q. Q. Hoang, 2019, Bioorganic & medicinal chemistry letters.

Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus.

Steven M. Johnson, José F. Victorino, E. Chapman, 2018, Journal of medicinal chemistry.

Combating Parkinson’s disease-associated toxicity by modulating proteostasis

Q. Q. Hoang, Yangshin Park, 2017, Proceedings of the National Academy of Sciences.

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.

Steven M. Johnson, T. Parish, E. Chapman, 2019, Bioorganic & medicinal chemistry letters.

The Parkinson's disease–associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2

Q. Q. Hoang, Xuwei Long, Chunxiang Wu, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein

David W. Miller, G. Petsko, M. Cookson, 2016, Proceedings of the National Academy of Sciences.

Pathway for Parkinson disease

Q. Q. Hoang, 2014, Proceedings of the National Academy of Sciences.

A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms

Steven M. Johnson, M. Cookson, R. Nichols, 2019, bioRxiv.

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

G. Petsko, E. Bézard, D. Ringe, 2016, Proceedings of the National Academy of Sciences.

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT

Todd A. Stone, G. Petsko, D. Ringe, 2013, Proceedings of the National Academy of Sciences.