W. Niforatos

发表

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

J. Segreti, S. Baker, Robert G. Schmidt, 2011, PAIN.

Distribution and functional characterization of human Nav1.3 splice variants

M Gopalakrishnan, T. Neelands, M. Gopalakrishnan, 2005, The European journal of neuroscience.

P2X receptor-mediated ionic currents in dorsal root ganglion neurons.

E A Kowaluk, T. van Biesen, E. Burgard, 1999, Journal of neurophysiology.

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat

P. Honore, M. Jarvis, K. Kage, 2002, Experimental Brain Research.

Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists

D. Donnelly-roberts, P. Honore, M. Jarvis, 2006 .

Ganglion Neurons Mediated Ionic Currents in Dorsal Root - P2X Receptor

S. Silberberg, C. Coddou, Zonghe Yan, 2015 .

Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states

J. Sullivan, C. Shieh, S. Baker, 2006, Pain.

A mixed Ca channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain

A. Swensen, Lance Lee, M. Jarvis, 2013 .

Comparative analysis of inactivated-state block of N-type (Cav2.2) calcium channels

D. Donnelly-roberts, A. Swensen, T. Neelands, 2011, Inflammation Research.

A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid

A. Gomtsyan, J. Sullivan, Chih-Hung Lee, 2005, Journal of Pharmacology and Experimental Therapeutics.

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat

T. Brennan, J. Sullivan, M. Williams, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Uninjured Rats Dynamic Range Neurons in CFA-Treated and Selective TRPV1 Receptor Antagonist, on Wide Systemic and Site-Specific Effects of A-425619, a

J. Brioni, A. Swensen, Lance Lee, 2015 .

TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists

A. Gomtsyan, J. Sullivan, M. Decker, 2006, The Journal of Neuroscience.

Pharmacological characterization of recombinant human and rat P2X receptor subtypes.

T. van Biesen, E. Burgard, E. Touma, 1999, European journal of pharmacology.

Characterization of the triazine, T4, a representative from a novel series of CaV2 inhibitors with strong state-dependence, poor use-dependence, and distinctively fast kinetics.

A. Swensen, Chih-Hung Lee, M. Jarvis, 2014, European journal of pharmacology.

A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats.

M. Jarvis, Qingwei Zhang, S. Joshi, 2014, Biochemical pharmacology.

Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.

A. Swensen, Chih-Hung Lee, T. Neelands, 2014, The journal of pain : official journal of the American Pain Society.

A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain.

A. Swensen, Lance Lee, M. Jarvis, 2014, Journal of neurophysiology.

A mixed Ca 2 channel blocker , A-1264087 , utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain

A. Swensen, Lance Lee, M. Jarvis, 2013 .

(R)-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo

A. Gomtsyan, J. Sullivan, Chih-Hung Lee, 2008, Journal of Pharmacology and Experimental Therapeutics.

Utility of Large-Scale Transiently Transfected Cells for Cell-Based High-Throughput Screens to Identify Transient Receptor Potential Channel A1 (TRPA1) Antagonists

Jing Xu, Murali Gopalakrishnan, Wende Niforatos, 2007, Journal of biomolecular screening.

Molecular and Functional Characterization of Human P2X2 Receptors

E. Burgard, E. Touma, M. Jarvis, 1999 .

2′, 3′‐O‐(2,4,6,Trinitrophenyl)‐ATP and A‐317491 are competitive antagonists at a slowly desensitizing chimeric human P2X3 receptor

H. McDonald, M. Jarvis, W. Niforatos, 2003, British journal of pharmacology.

Competitive antagonism of recombinant P2X(2/3) receptors by 2', 3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP).

T. van Biesen, E. Burgard, E. Touma, 2000, Molecular pharmacology.

Allosteric modulation and accelerated resensitization of human P2X(3) receptors by cibacron blue.

E A Kowaluk, T. van Biesen, E. Burgard, 1999, The Journal of pharmacology and experimental therapeutics.

Electrophysiological Characterization of Recombinant and Native P2X Receptors

M. Jarvis, W. Niforatos, 2004, Current protocols in pharmacology.

A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.

A. Swensen, T. Neelands, T. Vortherms, 2012, Biochemical pharmacology.

P 2 X Receptor – Mediated Ionic Currents in Dorsal Root Ganglion Neurons

E. Burgard, E. Touma, M. Jarvis, 1999 .

Activation of TRPA1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3′-Carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597)

T. Holzman, T. Neelands, R. Moreland, 2007, Molecular Pharmacology.

Molecular and Functional Characterization of Human P 2 X 2 Receptors

E. Burgard, E. Touma, M. Jarvis, 1999 .

Molecular and functional characterization of human P2X(2) receptors.

T. van Biesen, E. Burgard, E. Touma, 1999, Molecular pharmacology.

Competitive Antagonism of Recombinant P 2 X 2 / 3 Receptors by 2 9 , 3 9-O-( 2 , 4 , 6-Trinitrophenyl ) Adenosine 5 9-Triphosphate ( TNP-ATP )

E. Burgard, E. Touma, M. Jarvis, 2000 .

Activation of TRPA 1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3-Carbamoylbiphenyl-3-yl cyclohexylcarbamate ( URB 597 )

T. Holzman, T. Neelands, R. Moreland, 2007 .

Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²⁺ channel blockers with analgesic activity.

Jill M. Wetter, R. Henry, A. Swensen, 2012, Bioorganic & medicinal chemistry.

A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats.

M. Jarvis, Qingwei Zhang, S. Joshi, 2014, Biochemical pharmacology.

An automated electrophysiological assay for differentiating Ca(v)2.2 inhibitors based on state dependence and kinetics.

A. Swensen, Lance Lee, T. Vortherms, 2012, Assay and drug development technologies.

A. Gomtsyan, J. Sullivan, Chih-Hung Lee, 2008, Journal of Pharmacology and Experimental Therapeutics.

Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.

A. Swensen, Chih-Hung Lee, T. Neelands, 2014, The journal of pain : official journal of the American Pain Society.