A. Frackelton

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Wortmannin, a phosphoinositide 3-kinase inhibitor, selectively enhances cytotoxicity of receptor-directed-toxin chimeras in vitro and in vivo.

P. Davol, A. Bizuneh, A. Frackelton, 1999, Anticancer research.

Identification of tyrosine‐phosphorylated colony‐stimulating factor 1 (CSF‐1) receptor and a 56‐kilodalton protein phosphorylated in intact human cells in response to CSF‐1

A. Frackelton, R. Huhn, M. E. Cicione, 1989, Journal of cellular biochemistry.

Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNA

L. Mahadevan, W. Colledge, J. Bell, 1987, Nature.

Application of a galactosidase immunosorbent test to carcinoembryonic antigen in plasma.

J. Weltman, A. Frackelton, 1976, Cancer research.

Platelet-derived growth factor indirectly stimulates angiogenesis in vitro.

N. Sato, J. Clark, J. Kato, 1993, The American journal of pathology.

Tyrosine phosphorylated proteins in chronic myelogenous leukemia.

J. Clark, A. Frackelton, P. S. Kumar, 1993, Leukemia & lymphoma.

p 66 Shc Tumor Levels Show a Strong Prognostic Correlation with Disease Outcome in Stage IIAColon Cancer

S. Grossman, C. Hsieh, S. Lyle, 2007 .

Combining suramin and a chimeric toxin directed to basic fibroblast growth factor receptors increases therapeutic efficacy against human melanoma in an animal model

P. Davol, A. Frackelton, S. Garza, 1999, Cancer.

Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells.

L. E. Stevenson, K. Ravichandran, A. Frackelton, 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Targeting human prostatic carcinoma through basic fibroblast growth factor receptors in an animal model: Characterizing and circumventing mechanisms of tumor resistance

P. Davol, A. Frackelton, 1999, The Prostate.

Actions of TNF and INF-γ on Angiogenesis In Vitro

N. Sato, H. Nariuchi, N. Tsuruoka, 1990 .

Autocrine down-regulation of basic fibroblast growth factor receptors causes mitotoxin resistance in a human melanoma cell line.

P. Davol, A. Frackelton, J. Beitz, 1995, The Journal of investigative dermatology.

Monoclonal antibodies and immobilized antibodies

C. A. White, R. Krauss, M. Melamed, 1987 .

Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the RAS signaling pathway

L. E. Stevenson, A. Frackelton, Jeffrey W. Clark, 1996, International journal of cancer.

Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells.

P. Gruppuso, A. Frackelton, C. Boney, 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Human microvascular endothelial cells express receptors for platelet-derived growth factor.

I. S. Kim, A. Frackelton, P. Calabresi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Constitutively tyrosine phosphorylated p52 Shc in breast cancer cells: correlation with ErbB2 and p66 Shc expression

L. E. Stevenson, A. Frackelton, Lisa E. Stevenson, 1998, Breast Cancer Research and Treatment.

Generation of monoclonal antibodies against phosphotyrosine and their use for affinity purification of phosphotyrosine-containing proteins.

M. Posner, A. Frackelton, F. Mermelstein, 1991, Methods in enzymology.

Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells

A. Ross, H. Eisen, A. Frackelton, 1983, Molecular and cellular biology.

Synthesis of λ1, λ2, and λ3 light chains by mouse spleen B cells

H. Eisen, A. Frackelton, E. Reilly, 1982 .

Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus.

D. Baltimore, M. Chow, J. Foulkes, 1985, The Journal of biological chemistry.

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine.

L. Williams, A. Frackelton, P. Tremble, 1984, The Journal of biological chemistry.

Stimulation of factor-dependent myeloid cell lines with interleukin 3 induces tyrosine phosphorylation of several cellular substrates.

J. Ihle, J. Ihle, A. Frackelton, 1988, The Journal of biological chemistry.

Shc Dominant Negative Disrupts Cell Cycle Progression in Both G 0G 1 and G 2M of ErbB 2-positive Breast Cancer Cells 1

L. E. Stevenson, K. Ravichandran, A. Frackelton, 1998 .

Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.

J. Schwarzbauer, Minsoo Kim, A. Frackelton, 2009, Molecular endocrinology.

Functional diversity of antibodies elicited by bacterial beta-D-galactosidase. Monoclonal activating, inactivating, protecting, and null antibodies to normal enzyme.

B. Rotman, A. Frackelton, 1980, The Journal of biological chemistry.

In Pursuit of Safety: Systemic Bicycle Crash Analysis in Seattle, WA

Bo Lan, Libby Thomas, Alexandra Frackelton, 2017 .

Saporin toxins directed to basic fibroblast growth factor receptors effectively target human ovarian teratocarcinoma in an animal model

J. Cook, D. Lappi, W. Ying, 1995, Cancer.

Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo.

J. Clark, D. Lappi, A. Baird, 1992, Cancer research.

Protein-Tyrosine Kinase Activity and pp 60 " ~ ircExpression in Whole Cells Measured by Flow Cytometry 1

F. Waldman, H. Saya, V. Levin, 2006 .

The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes.

P. Gruppuso, A. Frackelton, C. Boney, 2000, Molecular endocrinology.

Aerotropolis Atlanta Brownfield Redevelopment Health Impact Assessment

Michael Elliott, Arthi Rao, Catherine L. Ross, 2011 .

The mitotoxin, basic fibroblast growth factor-saporin, effectively targets human prostatic carcinoma in an animal model.

P. Davol, A. Frackelton, 1996, The Journal of urology.

Purification of the platelet-derived growth factor receptor by using an anti-phosphotyrosine antibody.

L. Williams, A. Frackelton, T. Daniel, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells.

J. Avruch, R. Nemenoff, H. Tornqvist, 1988, The Journal of biological chemistry.

Diffusion control of the binding of carcinoembryonic antigen (CEA) with insoluble anti-CEA antibody.

J. Weltman, A. Frackelton, 1980, Journal of immunology.

Receptors for platelet-derived growth factor on microvascular endothelial cells.

I. S. Kim, A. Frackelton, P. Calabresi, 1992, EXS.

Mechanisms of transformation by protein-tyrosine kinases.

W. Colledge, M. J. Fry, J. Bell, 1988, Advances in experimental medicine and biology.

Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1.

W. Liu, E. Stanley, Y. Yeung, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Actions of TNF and IFN-gamma on angiogenesis in vitro.

N. Sato, H. Nariuchi, N. Tsuruoka, 1990, The Journal of investigative dermatology.

Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines.

D. Brautigan, L. Lu, M. Posner, 1992, Cancer research.

N-(3-pyrene)maleimide: a long lifetime fluorescent sulfhydryl reagent.

J. Weltman, R. Dowben, R. Szaro, 1973, The Journal of biological chemistry.

Increased Levels of Mitochondrial DNA in an Etoposide-resistant Human Monocytic Leukaemia Cell Line (THIWE)

M. Posner, A. Frackelton, M. Tumber, 1991 .

A Galactosidase Immunosorbent Test for Carcinoembryonic Antigen 1

J. Weltman, R. Szaro, A. Frackelton, 2006 .

Applicationof a Galactosidase ImmunosorbentTest to CarcinoembryonicAntigen in Plasma1

J. Weltman, A. Frackelton, 1976 .

Estrogen Action Via the G Protein-Coupled Receptor , GPR 30 : Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

K. Bland, A. Frackelton, E. Filardo, 2001 .

A galactosidase immunosorbent test for carcinoembryonic antigen.

J. Weltman, R. Szaro, A. Frackelton, 1976, Cancer research.

Identification of insulin receptor tyrosine residues autophosphorylated in vitro.

J. Avruch, R. Nemenoff, H. Tornqvist, 1987, The Journal of biological chemistry.

Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues.

M. Posner, J. Foulkes, A. Frackelton, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

T. Sugimura, A. Ross, M. Rosner, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Changes in tyrosine-phosphorylated p190 and its association with p120 type I and p100 type II rasGAPs during myelomonocytic differentiation of human leukemic cells.

J. Settleman, E. Bearer, J. Clark, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF.

K. Bland, A. Frackelton, E. Filardo, 2000, Molecular endocrinology.

Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer.

R. Bagdasaryan, P. Davol, A. Frackelton, 2003, Cancer research.

A galactosidase immunosorbent test for human immunoglobulin E.

J. Weltman, B. Rotman, R. Szaro, 1976, The Journal of allergy and clinical immunology.

LAMBDA LIGHT CHAINS AND IDIOTYPE-BEARING T CELLS

H. Eisen, A. Frackelton, T. Azuma, 1980 .

p66 Shc Tumor Levels Show a Strong Prognostic Correlation with Disease Outcome in Stage IIA Colon Cancer

S. Grossman, C. Hsieh, S. Lyle, 2007, Clinical Cancer Research.

Modulation of p53 expression by human recombinant interferon-alpha2a correlates with abrogation of cisplatin resistance in a human melanoma cell line.

P. Davol, A. Frackelton, J. Darnowski, 1996, Cancer research.