M. Nielsen

T. Andresen, L. B. Thomsen, B. Brodin, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Sortilin regulates blood–brain barrier integrity

M. Nyegaard, T. Andresen, B. Brodin, 2021, The FEBS journal.

Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP–SorLA Interaction

O. Andersen, C. Matrone, M. Nielsen, 2015, Front. Cell. Neurosci..

Functional Organization of the Sortilin Vps10p Domain*

P. Madsen, E. S. Sørensen, A. Nykjær, 2004, Journal of Biological Chemistry.

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC.

P. Højrup, H. Hager, R. Jakes, 1997, The Biochemical journal.

Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain

C. Andersen, M. Nielsen, B. O. Krogh, 2020, Scientific Reports.

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells

J. Bonifacino, P. Madsen, G. Olivecrona, 2016, The FEBS journal.

Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier

L. B. Thomsen, M. Nielsen, T. Moos, 2016, Molecular Neurobiology.

Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers

P. Alam, D. Otzen, M. Nielsen, 2021, Fluids and Barriers of the CNS.

Molecular Identification of a Novel Candidate Sorting Receptor Purified from Human Brain by Receptor-associated Protein Affinity Chromatography*

N. Tommerup, S. Moestrup, P. Madsen, 1997, The Journal of Biological Chemistry.

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

A. Beaudet, P. Sarret, T. Stroh, 2003, The Journal of comparative neurology.

The Yeast Vps10p Cytoplasmic Tail Mediates Lysosomal Sorting in Mammalian Cells and Interacts with Human GGAs*

P. Madsen, M. Nielsen, C. Petersen, 2002, The Journal of Biological Chemistry.

Ultrathin Silicon Membranes for In Situ Optical Analysis of Nanoparticle Translocation across a Human Blood-Brain Barrier Model.

K. Dawson, J. McGrath, T. Khire, 2020, ACS nano.

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

T. Andresen, F. Melander, P. Kempen, 2017, Scientific Reports.

Binding of A β to α-and β-synucleins : identification of segments in α-synuclein / NAC precursor that bind A β and NAC

H. Hager, R. Jakes, J. Gliemann, 1997 .

Analysis of the Binding of Pro-urokinase and Urokinase-Plasminogen Activator Inhibitor-1 Complex to the Low Density Lipoprotein Receptor-related Protein Using a Fab Fragment Selected from a Phage-displayed Fab Library (*)

S. Moestrup, A. V. van Zonneveld, H. Pannekoek, 1995, The Journal of Biological Chemistry.

Analysis of ligand binding to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site.

A. Schwartz, J. Gliemann, A. Nykjaer, 1995, The Journal of biological chemistry.

Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins.

U. Cavallaro, M. Soria, A. Nykjaer, 1995, European journal of biochemistry.

Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain.

P. Madsen, J. Gliemann, M. Nielsen, 1996, Biochimica et biophysica acta.

The sorLA cytoplasmic domain interacts with GGA1 and ‐2 and defines minimum requirements for GGA binding

A. Smit, W. Geraerts, P. Madsen, 2002, FEBS letters.

Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover

P. Madsen, J. Bauer, M. Nielsen, 2016, Molecular and Cellular Biology.

Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers

R. Holm, B. Brodin, H. C. Helms, 2016, Molecular and Cellular Neuroscience.

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D3

J. Fyfe, A. de la Chapelle, S. Moestrup, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The carboxy‐terminal domain of the receptor‐associated protein binds to the Vps10p domain of sortilin

S. Moestrup, P. Madsen, L. Ellgaard, 1998, FEBS letters.

A carboxyl-terminal fragment of lipoprotein lipase binds to the low density lipoprotein receptor-related protein and inhibits lipase-mediated uptake of lipoprotein in cells.

G. Olivecrona, U. Beisiegel, N. Meyer, 1994, The Journal of biological chemistry.

Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells

T. Andresen, C. Hempel, A. Urquhart, 2021, PloS one.

Dynamics of Rab7b‐Dependent Transport of Sorting Receptors

C. Bucci, O. Bakke, C. Progida, 2012, Traffic.

SorCS2 deletion leads to altered neuronal lysosome activity

T. G. Oliveira, M. Nielsen, A. Tóth, 2021, bioRxiv.

Sortilins in the blood-brain barrier: impact on barrier integrity

M. Nielsen, A. Tóth, 2022, Neural regeneration research.

Expression of tissue transglutaminase in human bladder carcinoma

S. Hamilton-Dutoit, H. Hager, J. Gliemann, 1997, The Journal of pathology.

The concentration of extracellular superoxide dismutase in plasma is maintained by LRP-mediated endocytosis.

J. Crapo, J. Enghild, S. Moestrup, 2010, Free radical biology & medicine.

The human keratinocyte two‐dimensional gel protein database (update 1992): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

Joël Vandekerckhove, H. Leffers, B. Honoré, 1992, Electrophoresis.

SorCS3 does not require propeptide cleavage to bind nerve growth factor

P. Madsen, E. S. Sørensen, C. M. Petersen, 2005, FEBS letters.

Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families*

G. Olivecrona, S. Christensen, M. Nielsen, 2008, Journal of Biological Chemistry.

α-Synuclein Binds to Tau and Stimulates the Protein Kinase A-catalyzed Tau Phosphorylation of Serine Residues 262 and 356*

P. Højrup, H. Hager, R. Jakes, 1999, The Journal of Biological Chemistry.

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

M. Nyegaard, O. Bakke, G. Olivecrona, 2011, Journal of Cell Science.

Sortilin, Encoded by the Cardiovascular Risk Gene SORT1, and Its Suggested Functions in Cardiovascular Disease

M. Nielsen, C. Petersen, M. Kjolby, 2015, Current Atherosclerosis Reports.

The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein

P. Madsen, E. Christensen, A. Nykjær, 2001, The EMBO journal.

Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin

P. Sarret, C. M. Petersen, M. Nielsen, 2001, FEBS letters.

Sortilin/Neurotensin Receptor-3 Binds and Mediates Degradation of Lipoprotein Lipase*

G. Olivecrona, C. M. Petersen, J. Gliemann, 1999, The Journal of Biological Chemistry.

Propeptide cleavage conditions sortilin/neurotensin receptor‐3 for ligand binding

S. Moestrup, P. Madsen, J. Gliemann, 1999, The EMBO journal.

The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain

Joachim Herz, Daniela Hartl, Guido Mastrobuoni, 2013, The Journal of Neuroscience.

Different Motifs Regulate Trafficking of SorCS1 Isoforms

Dietmar Kuhl, P. Madsen, A. Engelsberg, 2008, Traffic.

Cyclic Hypoxia Conditioning Alters the Content of Myoblast-Derived Extracellular Vesicles and Enhances Their Cell-Protective Functions

H. Bøtker, J. Kjems, B. Blagoev, 2021, Biomedicines.

The effect of hypoxia on ZEB1 expression in a mimetic system of the blood-brain barrier.

A. Børglum, J. Christensen, P. Qvist, 2019, Microvascular research.

Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers

D. Otzen, M. Nielsen, P. Jensen, 2022, Fluids and Barriers of the CNS.

Mapping Receptor Antibody Endocytosis and Trafficking in Brain Endothelial Cells.

M. Nielsen, Mikkel R. Holst, S. Nielsen, 2020, Methods in molecular biology.

Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells

B. Brodin, M. Nielsen, Mikkel R. Holst, 2023, Fluids and Barriers of the CNS.

Vesicular Transport Machinery in Brain Endothelial Cells: What We Know and What We Don`t.

M. Nielsen, A. Tóth, Mikkel R. Holst, 2020, Current pharmaceutical design.

Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells.

J. Preston, N. Abbott, M. Nielsen, 2017, Journal of visualized experiments : JoVE.

The Multiligand α2‐Macroglobulin Receptor/Low Density Lipoprotein Receptor‐Related Protein (α2MR/LRP)

S. Moestrup, P. Andreasen, G. Olivecrona, 1994 .

The multiligand alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands.

S. Moestrup, P. Andreasen, G. Olivecrona, 1994, Annals of the New York Academy of Sciences.

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

M. Nyegaard, G. Halliday, T. Andresen, 2016, PloS one.

The human keratinocyte two‐dimensional gel protein database: Update 1993

H. Leffers, B. Honoré, J. Vandekerckhove, 1993, Electrophoresis.

Maternally contributed Nlrp9b expressed in human and mouse ovarian follicles contributes to early murine preimplantation development

L. Sunde, E. Ernst, M. Nielsen, 2020, Journal of Assisted Reproduction and Genetics.

The Endo-Lysosomal System of Brain Endothelial Cells Is Influenced by Astrocytes In Vitro

L. B. Thomsen, P. Madsen, H. Lohi, 2018, Molecular Neurobiology.

Human cellular protein patterns and their link to genome DNA mapping and sequencing data: towards an integrated approach to the study of gene expression.

H. Leffers, B. Honoré, J. Vandekerckhove, 1993, Genetic engineering.

Sorting by the Cytoplasmic Domain of the Amyloid Precursor Protein Binding Receptor SorLA

J. Nyengaard, P. Madsen, O. Bakke, 2007, Molecular and Cellular Biology.

cDNA expression and human two‐dimensional gel protein databases: Towards integrating DNA and protein information

H. Leffers, B. Honoré, J. Celis, 1996, Electrophoresis.

Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner

J. Nyengaard, J. Lykkesfeldt, A. Nykjær, 2018, Behavioural Brain Research.

The receptor‐associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin‐dependent kinase II.

H. Vorum, F. Vilhardt, L. Ellgaard, 1996, The EMBO journal.

Ca2+ Binding to α-Synuclein Regulates Ligand Binding and Oligomerization*

H. Vorum, M. Nielsen, P. Jensen, 2001, The Journal of Biological Chemistry.

Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device

J. McGrath, S. Vergo, M. Nielsen, 2023, International journal of molecular sciences.

Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton.

J Vandekerckhove, H. Leffers, B. Honoré, 1993, Experimental cell research.

Microtubule-associated Protein 1B Is a Component of Cortical Lewy Bodies and Binds α-Synuclein Filaments*

J. Kenney, W. Gai, M. Nielsen, 2000, The Journal of Biological Chemistry.

Contribution of the carboxy-terminal domain of lipoprotein lipase to interaction with heparin and lipoproteins.

G. Olivecrona, J. Gliemann, M. Nielsen, 2000, Biochemical and biophysical research communications.

Caspase-mediated Parkin Cleavage in Apoptotic Cell Death*

M. Nielsen, P. Jensen, S. Kahns, 2002, The Journal of Biological Chemistry.

HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA

M. Nyegaard, P. Madsen, M. Nielsen, 2019, Scientific Reports.

SorLA in astrocytes regulates blood-brain barrier integrity

B. Brodin, M. Nielsen, A. Tóth, 2023, Frontiers in Drug Delivery.

Basigin Antibodies with Capacity for Drug Delivery Across Brain Endothelial Cells

M. Nielsen, Sarah Christine Christensen, A. Jensen, 2021, Molecular Neurobiology.

Random Uptake Conditions the Hit-and-run Method High-flux Backbone

P. Madsen, K. Teng, B. Hempstead, 2022 .

Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters

M. Nielsen, P. Siupka, Stine C. Klinger, 2015, Membranes.

The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells

N. Abbott, M. Nielsen, A. Tóth, 2019, Fluids and barriers of the CNS.

Activation and Functional Characterization of the Mosaic Receptor SorLA/LR11*

P. Madsen, J. Gliemann, C. Jacobsen, 2001, The Journal of Biological Chemistry.

Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heterodimer

J. Scheller, P. Madsen, M. Nielsen, 2010, Molecular and Cellular Biology.

Maternally Contributed Folate Receptor 1 Is Expressed in Ovarian Follicles and Contributes to Preimplantation Development

T. Strandgaard, E. Ernst, M. Nielsen, 2017, Front. Cell Dev. Biol..

Transport of a Peptide from Bovine αs1-Casein across Models of the Intestinal and Blood–Brain Barriers

J. Enghild, C. Scavenius, J. Rasmussen, 2020, Nutrients.

Different Motifs Regulate Trafficking of SorCS1 Isoforms

Dietmar Kuhl, P. Madsen, A. Engelsberg, 2008, Traffic.

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

M. Nyegaard, O. Bakke, G. Olivecrona, 2011 .