J. Batra

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Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition.

Deepa Sikriwal, Paroma Ghosh, J. Batra, 2008, The international journal of biochemistry & cell biology.

Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv)

I. Pastan, D. Fitzgerald, V. Chaudhary, 1991, Molecular and cellular biology.

Localization of the catalytic activity in restrictocin molecule by deletion mutagenesis.

S. Nayak, J. Batra, Shveta, 2000, European journal of biochemistry.

Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function

J. Batra, Alla Singh, Shah Ubaid-ullah, 2016, PloS one.

Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities.

J. Batra, Ayush Attery, 2017, International journal of biological macromolecules.

Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens

J. Batra, Anushka Malik, 2012, Critical reviews in microbiology.

Interaction of Human Pancreatic Ribonuclease with Human Ribonuclease Inhibitor

S. Swaminathan, J. Batra, D. Gaur, 2001, The Journal of Biological Chemistry.

Cloning, expression and efficient refolding of carbohydrate-peptide mimicry recognizing single chain antibody 2D10.

Lavanya Krishnan, D. Salunke, J. Batra, 2010, Protein expression and purification.

Direct incorporation of guanosine 5'-diphosphate into microtubules without guanosine 5'-triphosphate hydrolysis.

E. Hamel, J. Batra, C. Lin, 1986, Biochemistry.

Characterization and role of the N-terminal domain in its function

Deepa Sikriwal, P. Rath, J. Batra, 2008 .

Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

I. Pastan, M. Willingham, D. Fitzgerald, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines.

G. Goldenberg, A. Deffie, J. Batra, 1989, Cancer research.

Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium.

I. Pastan, M. Willingham, L. Pai, 1992, Cancer research.

Mycobacterium tuberculosis ClpC1

Deepa Sikriwal, P. Rath, J. Batra, 2008, The FEBS journal.

Heat Shock Proteins in Mycobacterium tuberculosis: Involvement in Survival and Virulence of the Pathogen

J. Batra, Divya N. Bajaj, Divya Bajaj, 2012 .

Role of DnaK in HspR‐HAIR interaction of Mycobacterium tuberculosis

J. Batra, Priyanka Parijat, 2015, IUBMB life.

Balsamin, a novel ribosome-inactivating protein from the seeds of Balsam apple Momordica balsamina

S. Yadav, M. Puri, S. Yadav, 2011, Amino Acids.

Insertion of constant region domains of human IgG1 into CD4-PE40 increases its plasma half-life.

I. Pastan, S. Kasturi, V. Chaudhary, 1993, Molecular immunology.

Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys.

I. Pastan, M. Willingham, D. Fitzgerald, 1992, Cancer research.

TGFα-anti-Tac(Fv)-PE40: A bifunctional toxin cytotoxic for cells with EGF or IL2 receptors

I. Pastan, V. Chaudhary, J. Batra, 1990 .

Antitumor activity of a thioether-linked immunotoxin: OVB3-PE.

I. Pastan, M. Willingham, D. Fitzgerald, 1990, Bioconjugate chemistry.

Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.

I. Pastan, D. Fitzgerald, M. Gately, 1990, The Journal of biological chemistry.

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine inhibits proton motive force in energized liver mitochondria.

R. Bhatnagar, G. Krishna, J. Batra, 1989, Archives of biochemistry and biophysics.

The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to rRNA N-glycosidase and internucleosomal DNA fragmentation

D. Seth, S. Bagga, J. Batra, 2002 .

Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins.

A. Goyal, J. Batra, Anita Goyal, 2000, The Biochemical journal.

Mechanism of HrcA function in heat shock regulation in Mycobacterium tuberculosis.

J. Batra, Priyanka Parijat, Owais R. Hakiem, 2019, Biochimie.

ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli.

J. Batra, S. Kumari, Owais R. Hakiem, 2020, International journal of medical microbiology : IJMM.

Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia.

G. Goldenberg, A. Deffie, T. Shea, 1988, Cancer research.

Cytotoxic activity of ribonucleolytic toxin restrictocin‐based chimeric toxins targeted to epidermal growth factor receptor

J. Batra, D. Rathore, 1997, FEBS letters.

Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.

I. Pastan, M. Willingham, D. Fitzgerald, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cytotoxicity of ribosome‐inactivating protein saporin is not mediated through α2‐macroglobulin receptor

S. Bagga, J. Batra, M. Hosur, 2003, FEBS letters.

Role of unique basic residues of human pancreatic ribonuclease in its catalysis and structural stability.

F. Ahmad, A. Islam, J. Batra, 2007, Biochemical and biophysical research communications.

Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.

I. Pastan, D. Fitzgerald, S. Seetharam, 1993, Bioconjugate chemistry.

Human eosinophil cationic protein manifests alarmin activity through its basicity and ribonuclease activity

P. Tailor, J. Batra, Ayush Attery, 2021, bioRxiv.

Functional role of putative critical residues in Mycobacterium tuberculosis RNase P protein.

J. Batra, Alla Singh, Shah Ubaid-ullah, 2016, The international journal of biochemistry & cell biology.

Insight into the role of histidine in RNR motif of protein component of RNase P of M. tuberculosis in catalysis

J. Batra, Alla Singh, Anup K. Ramteke, 2016, IUBMB life.

A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins.

I. Pastan, M. Willingham, D. Fitzgerald, 1990, Proceedings of the National Academy of Sciences of the United States of America.

In vitro and in vivo activity of a recombinant toxin, OLX-209, which targets the erbB-2 oncoprotein.

I. Pastan, R. Bird, J. Batra, 1994, Advances in enzyme regulation.

Antimicrobial Activity of Human Eosinophil Granule Proteins.

J. Batra, A. Chopra, 2021, Methods in molecular biology.

Antimicrobial activity of human eosinophil granule proteins.

J. Batra, A. Chopra, 2014, Methods in molecular biology.

Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.

I. Pastan, R. Bird, J. Batra, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Molecular and immunological characterization of cysteine protease from Phaseolus vulgaris and evolutionary cross-reactivity.

N. Arora, S. Gaur, J. Batra, 2022, Journal of food biochemistry.

Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.

E. Hamel, L. Jurd, J. Batra, 1985, Molecular pharmacology.

Heat Shock Proteins in the Pathogenesis of Mycobacterium tuberculosis

J. Batra, Prajna Tripathi, 2019, Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions.

In vitro and in silico studies of urea-induced denaturation of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C

F. Ahmad, A. Islam, J. Batra, 2015, Journal of biomolecular structure & dynamics.

Involvement of loops L2 and L4 of ribonucleolytic toxin restrictocin in its functional activity.

J. Batra, Manisha Tripathi, Punyatirtha Dey, 2007, Protein and peptide letters.

Role of cis prolines 112 and 126 in the functional activity of ribonucleolytic toxin restrictocin.

D. Seth, A. Goyal, J. Batra, 2002, Biochemical and biophysical research communications.

Role of individual cysteine residues and disulfide bonds in the structure and function of Aspergillus ribonucleolytic toxin restrictocin.

S. Nayak, J. Batra, D. Rathore, 1999, Biochemistry.

Ribosome Inactivating Proteins and Apoptosis

Deepa Sikriwal, J. Batra, 2010 .

The differential catalytic activity of ribosome-inactivating proteins saporin 5 and 6 is due to a single substitution at position 162.

Paroma Ghosh, J. Batra, 2006, The Biochemical journal.

The Cytotoxic Activity of Ribosome-inactivating Protein Saporin-6 Is Attributed to Its rRNA N-Glycosidase and Internucleosomal DNA Fragmentation Activities*

D. Seth, S. Bagga, J. Batra, 2003, The Journal of Biological Chemistry.

Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin.

S. Bagga, D. Salunke, S. Nayak, 2001, Biochemistry.

Construction, expression and characterization of chimaeric toxins containing the ribonucleolytic toxin restrictocin: intracellular mechanism of action.

J. Batra, D. Rathore, 1997, The Biochemical journal.

Expression of ribonucleolytic toxin restrictocin in Escherichia coli: purification and characterization

J. Batra, D. Rathore, S. Nayak, 1996, FEBS letters.

Generation of active immunotoxins containing recombinant restrictocin.

J. Batra, D. Rathore, 1996, Biochemical and Biophysical Research Communications - BBRC.

Overproduction of fungal ribotoxin alpha-sarcin in Escherichia coli: generation of an active immunotoxin.

S. Nayak, J. Batra, D. Rathore, 1997, Gene.

Ribotoxin restrictocin manifests anti-HIV-1 activity through its specific ribonuclease activity.

S. Yadav, J. Batra, 2015, International journal of biological macromolecules.

Mechanism of Anti-HIV Activity of Ribosome Inactivating Protein, Saporin.

S. Yadav, J. Batra, 2015, Protein and peptide letters.

Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.

F. Hess, E. Hamel, J. Batra, 1986, Cancer research.

Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein

J. Batra, Anubha Singh, 2011, Biological chemistry.

Functional Role of Glutamine 28 and Arginine 39 in Double Stranded RNA Cleavage by Human Pancreatic Ribonuclease

F. Ahmad, M. Rehman, J. Batra, 2011, PloS one.

The amino‐terminal domain of Mycobacterium tuberculosis ClpB protein plays a crucial role in its substrate disaggregation activity

J. Batra, V. Patel, Priyanka Parijat, 2018, FEBS open bio.

Effects of pH on tubulin-nucleotide interactions.

A B Huang, A. B. Huang, E. Hamel, 1986, Archives of biochemistry and biophysics.

Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.

E. Hamel, L. Jurd, J. Batra, 1988, Biochemical pharmacology.

Morpholino derivatives of benzyl-benzodioxole, a study of structural requirements for drug interactions at the colchicine/podophyllotoxin binding site of tubulin.

E. Hamel, L. Jurd, J. Batra, 1986, Biochemical pharmacology.

An insertion in loop L7 of human eosinophil‐derived neurotoxin is crucial for its antiviral activity

D. Seth, S. Parveen, Deepa Sikriwal, 2012, Journal of cellular biochemistry.

Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C.

F. Ahmad, A. Islam, J. Batra, 2015, International journal of biological macromolecules.

Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different

F. Ahmad, A. Islam, J. Batra, 2017, Journal of biomolecular structure & dynamics.

Human pancreatic ribonuclease--deletion of the carboxyl-terminal EDST extension enhances ribonuclease activity and thermostability.

J. Batra, H. Bal, 1997, European journal of biochemistry.

The C-Terminus of ClpC1 of Mycobacterium tuberculosis Is Crucial for Its Oligomerization and Function

J. Batra, Divya N. Bajaj, Divya Bajaj, 2012, PloS one.

A ribonuclease inhibitor resistant dimer of human pancreatic ribonuclease displays specific antitumor activity.

J. Batra, Ayush Attery, Prajna Tripathi, 2018, International journal of biological macromolecules.

Glycine 38 is crucial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA.

Deepak Gaur, D. Seth, J. Batra, 2002, Biochemical and biophysical research communications.

Role of aspartic acid 121 in human pancreatic ribonuclease catalysis

J. Batra, D. Gaur, 2005, Molecular and Cellular Biochemistry.

Balsamin, a novel ribosome-inactivating protein from the seeds of Balsam apple Momordica balsamina

S. Yadav, M. Puri, R. Gupta, 2012, Amino Acids.

Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins

A. Pardo, S. Barth, R. Verma, 2015, Applied Microbiology and Biotechnology.

Functional and structural characterization of Helicobacter pylori ClpX: a molecular chaperone of Hsp100 family.

P. Rath, J. Batra, P. Singh, 2012, Protein and peptide letters.

Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c

F. Ahmad, T. Singh, A. Islam, 2014, Journal of biomolecular structure & dynamics.

Role of a substrate binding pocket in the amino terminal domain of Mycobacterium tuberculosis caseinolytic protease B (ClpB) in its function

J. Batra, Sonam Grover, Prajna Tripathi, 2023, Journal of biomolecular structure & dynamics.

Insight into the functional role of unique determinants in RNA component of RNase P of Mycobacterium tuberculosis.

J. Batra, Alla Singh, 2018, International journal of biological macromolecules.

Nucleotide interconversions in microtubule protein preparations, a significant complication for accurate measurement of GTP hydrolysis in the presence of adenosine 5'-(beta, gamma-imidotriphosphate).

E. Hamel, J. Batra, C. Lin, 1987, Biochemistry.

Growth-promoting activity of desmopressin in murine leukemia cells treated in vitro.

G. Goldenberg, J. Batra, S. Beenken, 1988, Cancer research.

Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins

S. Barth, R. Verma, Swati Choudhary, 2015, Applied Microbiology and Biotechnology.

Inhibition of protein kinase C isozymes causes immune profile alteration and possibly decreased tumorigenesis in bladder cancer.

J. Batra, Usha Agrawal, Satya Sahay, 2023, American journal of cancer research.

Role of HrcA in stress management in Mycobacterium tuberculosis

J. Batra, Owais R. Hakiem, 2021, Journal of applied microbiology.

Human eosinophil-derived neurotoxin: involvement of a putative non-catalytic phosphate-binding subsite in its catalysis

D. Seth, Deepa Sikriwal, J. Batra, 2007, Molecular and Cellular Biochemistry.

Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.

I. Pastan, M. Gately, V. Chaudhary, 1990, The Journal of biological chemistry.