Kyeong Lee

发表

BAP1 Downregulates NRF2 Target Genes and Exerts Anti-Tumorigenic Effects by Deubiquitinating KEAP1 in Lung Adenocarcinoma

Y. Suh, Y. Keum, C. Lim, 2022, Antioxidants.

Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis

Jiwon Ahn, M. Won, Cho-Rock Jung, 2013, Apoptosis.

Fission yeast-based screening to identify putative HDAC inhibitors using a telomeric reporter strain.

Jiwon Ahn, M. Won, K. Chung, 2008, Molecules and cells.

Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1α/malate dehydrogenase 2 inhibitors.

M. Won, Yongseok Choi, Kyeong Lee, 2014, Journal of medicinal chemistry.

LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line.

M. Won, K. Chung, Yinglan Jin, 2010, Biochemical pharmacology.

A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling

Jiwon Ahn, M. Won, Bo-Kyung Kim, 2013, Cancer Chemotherapy and Pharmacology.

Activation of sonic hedgehog signaling by a Smoothened agonist restores congenital defects in mouse models of endocrine-cerebro-osteodysplasia syndrome

Jieun Song, J. Bok, H. Ko, 2019, EBioMedicine.

Synthesis and structure-activity relationship of (E)-phenoxyacrylic amide derivatives as hypoxia-inducible factor (HIF) 1α inhibitors.

M. Won, Bo-Kyung Kim, Kyeong Lee, 2012, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of 2-Aminoisonicotinic Acid Analogues as HIF-1α Inhibitors.

M. Won, Song-Kyu Park, Kiho Lee, 2010 .

p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis.

Kyoung-Jae Won, M. Won, J. Im, 2014, Biochimica et biophysica acta.

Recent updates on the development of ganetespib as a Hsp90 inhibitor

Kyeong Lee, Hyun-Kyung Choi, 2012, Archives of pharmacal research.

Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents.

M. Won, Bo-Kyung Kim, Kang-Yell Choi, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: part II.

M. Won, Bo-Kyung Kim, Jee Sun Yang, 2013, European journal of medicinal chemistry.

The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation

M. Won, Bo-Kyung Kim, J. Park, 2020, Experimental & Molecular Medicine.

Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes.

M. Won, Bo-Kyung Kim, Kyung-Bin Song, 2016, Bioconjugate chemistry.

Identification of malate dehydrogenase 2 as a target protein of the HIF-1 inhibitor LW6 using chemical probes.

S. Son, M. Won, Bo-Kyung Kim, 2013, Angewandte Chemie.

Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.

Kyeong Lee, Yan Xia, Hyun-Kyung Choi, 2012, European journal of medicinal chemistry.

LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slug

M. Won, Hyun-Jung Byun, M. Park, 2021, Antioxidants.

A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration

M. Won, Bo-Kyung Kim, Kyeong Lee, 2016, PloS one.

Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype.

C. López-Otín, J. Freije, Ho-Yyoung Lee, 2016, The Journal of clinical investigation.

Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis

Jiwon Ahn, M. Won, Cho-Rock Jung, 2013, Apoptosis.

A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor

Kyeong Lee, Hwan‐Mook Kim, 2011, Archives of pharmacal research.

NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription

Kyoung-Jae Won, M. Won, K. Chung, 2013, Apoptosis.

Recent updates on the development of ganetespib as a Hsp90 inhibitor

Kyeong Lee, Hyun-Kyung Choi, 2012, Archives of pharmacal research.

Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer

S. Paik, Mirang Kim, Seon-Young Kim, 2018, British Journal of Cancer.

The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth

M. Won, Bo-Kyung Kim, G. Hwang, 2017, Cell Death & Disease.

Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618.

Kyoung-Jae Won, Y. Oh, M. Won, 2011, Carcinogenesis.