P. Karuso

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Quality, not quantity: the role of natural products and chemical proteomics in modern drug discovery.

Peter Karuso, Andrew M. Piggott, P. Karuso, 2004, Combinatorial chemistry & high throughput screening.

Modern Methods for the Isolation of Natural Product Receptors

P. Karuso, 2010 .

Sterol composition and classification of the porifera

P. Karuso, P. R. Bergquist, R. C. Cambie, 1991 .

Quantitation of the anticancer drug abiraterone and its metabolite &Dgr;(4)‐abiraterone in human plasma using high‐resolution mass spectrometry

M. McKay, M. Molloy, H. Gurney, 2018, Journal of Pharmaceutical and Biomedical Analysis.

Epicocconone, A New Cell-Permeable Long Stokes' Shift Fluorescent Stain for Live Cell Imaging and Multiplexing

D. Veal, P. Karuso, H.-Y. Choi, 2006, Journal of Fluorescence.

Bisindole Alkaloids from a New Zealand Deep-Sea Marine Sponge Lamellomorpha strongylata

Andrew M. Piggott, P. Karuso, K. Ragini, 2019, Marine drugs.

Optimisation of the fluorescein diacetate antibacterial assay.

Andrew B. Mahon, J. Jamie, N. Brouwer, 2005, Journal of microbiological methods.

Three-component mannich-like reaction of 2-aminoimidazole

P. Karuso, S. Shengule, 2011 .

Natural Products in Polyclad Flatworms

Jorge Rodríguez, J. Williamson, P. Karuso, 2021, Marine drugs.

Chlorinated metabolites from Streptomyces sp. highlight the role of biosynthetic mosaics and superclusters in the evolution of chemical diversity.

Thomas J. Booth, Andrew M. Piggott, Y. Chooi, 2021, Organic & biomolecular chemistry.

Natural Products from Three Nudibranchs: Nembrotha kubaryana, Hypselodoris infucata and Chromodoris petechialis

P. Scheuer, P. Karuso, 2002, Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry.

Fluorometric assay for the determination of glutathione reductase activity.

Andrew M. Piggott, P. Karuso, 2007, Analytical chemistry.

Isolation of Terrabacter sp. Strain DDE-1, Which Metabolizes 1,1-Dichloro-2,2-Bis(4-Chlorophenyl)Ethylene when Induced with Biphenyl

P. Franzmann, J. Aislabie, P. Karuso, 1999, Applied and Environmental Microbiology.

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate.

H. Kwon, M. Gotsbacher, P. Karuso, 2019, ACS chemical biology.

5-Chloropicolinic acid is produced by specific degradation of 4-chlorobenzoic acid by Sphingomonas paucimobilis BPSI-3

P. Karuso, D. Jardine, A. Davison, 1999, Journal of Industrial Microbiology and Biotechnology.

Multiple O-Glycoforms on the Spore Coat Protein SP96 in Dictyostelium discoideum

K L Williams, N. Packer, K. Williams, 2000, The Journal of Biological Chemistry.

Novel secoiridoids with antioxidant activity from Australian olive mill waste.

P. Prenzler, K. Robards, P. Karuso, 2007, Journal of agricultural and food chemistry.

Synthesis of New BINAP-Based Aminophosphines and Their 31P-NMR Spectroscopy

P. Karuso, Mark B Richardson, Fei Liu, 2013, Molecules.

Solution structure of FK506 from nuclear magnetic resonance and molecular dynamics

H. Kessler, P. Karuso, D. Mierke, 1990 .

A gloverin-like antibacterial protein is synthesized in Helicoverpa armigera following bacterial challenge.

A. Gooley, D. Veal, A. Beattie, 1998, Developmental and comparative immunology.

Identifying the cellular targets of natural products using T7 phage display.

Andrew M. Piggott, P. Karuso, 2016, Natural product reports.

Pseudopeptidic sulfoxides: relative stability and absolute configuration of diastereomers

P. Karuso, J. Poudrel, 2000 .

Expanding antibiotic chemical space around the nidulin pharmacophore.

Andrew M. Piggott, E. Lacey, A. Crombie, 2018, Organic & biomolecular chemistry.

Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions

H. Kwon, P. Karuso, 2018, Proteome Science.

Isocyanoneopupukeanane, a new tricyclic sesquiterpene from a sponge

P. Scheuer, P. Karuso, A. Poiner, 1989 .

Banksialactones and Banksiamarins: Isochromanones and Isocoumarins from an Australian Fungus, Aspergillus banksianus.

Andrew M. Piggott, E. Lacey, J. Pitt, 2018, Journal of natural products.

A one-pot synthesis and biological activity of ageladine A and analogues.

L. Meijer, C. Parish, P. Karuso, 2011, Journal of medicinal chemistry.

Tracking of fast moving neuronal vesicles with ageladine A.

M. Köck, U. Bickmeyer, M. Heine, 2010, Biochemical and biophysical research communications.

Concise total synthesis of the marine natural product ageladine A.

P. Karuso, S. Shengule, 2006, Organic letters.

Rapid screening of the antimicrobial activity of extracts and natural products.

D. Veal, P. Karuso, S. Chand, 1994, The Journal of antibiotics.

Isolation and Structure Elucidation of Additional Alkaloids from the Tropical Rainforest Tree Galbulimima baccata.

L. Mander, P. Karuso, W. C. Taylor, 2021, Journal of natural products.

Hypervalent silicate-assisted azidation approach for the substituted azepane motif

P. Karuso, Fei Liu, Bilqees Sameem, 2022, Tetrahedron Letters.

Hydrolysis rates of alkyl and aryl sulfinamides: evidence of general acid catalysis

Andrew M. Piggott, P. Karuso, 2007 .

Probing site specificity of DNA binding metallointercalators by NMR spectroscopy and molecular modeling.

J. Mackay, P. Karuso, E. Proudfoot, 2001, Biochemistry.

132,173-cyclopheophorbide enol, the first porphyrin isolated from a sponge

P. Karuso, C. Rickard, P. R. Bergquist, 1986 .

Combinatorial synthesis of new fluorescent scaffolds using click chemistry

P. Karuso, Felix Cleemann, Wendy Loa Kum-Cheung, 2021, Tetrahedron Letters.

Solution structure and behaviour of Δ-cis-α-[Ru(R,R-picchxnMe2)(phi)]2+ by NMR spectroscopy and molecular modellingElectronic supplementary information (ESI) available: NMR spectra and selected NMR data. See http://www.rsc.org/suppdata/dt/b2/b208846k/

J. Mackay, P. Karuso, E. Proudfoot, 2003 .

Enantiodivergence in the Biosynthesis of Bromotyrosine Alkaloids from Sponges?

Andrew M. Piggott, J. Fromont, P. Karuso, 2017, Journal of natural products.

Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia.

P. Karuso, M. A. Qhotsokoane-Lusunzi, 2001, Journal of natural products.

Mechanism of reversible fluorescent staining of protein with epicocconone.

P. Karuso, D. R. Coghlan, J. Mackintosh, 2005, Organic letters.

Halopicolinic acids, novel products arising through the degradation of chloro- and bromo-biphenyl by Sphingomonas paucimobilis BPSI-3.

D. Veal, P. Karuso, D. Jardine, 1996, Canadian journal of microbiology.

Characterisation of a novel UV filter in the lens of the thirteen-lined ground squirrel (Ictidomys tridecemlineatus).

R. Truscott, Brian Lyons, J. Jamie, 2014, Experimental eye research.

Chemical Ecology of the Nudibranchs

P. Karuso, 1987 .

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

H. Kwon, M. Gotsbacher, P. Karuso, 2016, Proteome Science.

Antimicrobial mode of action of secretions from the metapleural gland of Myrmecia gulosa (Australian bull ant).

D. Veal, J. Trimble, A. Beattie, 1995, Canadian journal of microbiology.

Talauxins: Hybrid Phenalenone Dimers from Talaromyces stipitatus.

Andrew M. Piggott, E. Lacey, A. Crombie, 2020, Journal of natural products.

Epicocconone, a novel fluorescent compound from the fungus epicoccumnigrum.

Peter Karuso, P. Karuso, Phillip J L Bell, 2003, Journal of the American Chemical Society.

Formation of pigment precursor (+)-1''-methylene-6''-hydroxy-2H-furan-5''-one-catechin isomers from (+)-catechin and a degradation product of ascorbic acid in a model wine system.

A. C. Clark, P. Prenzler, G. Scollary, 2009, Journal of agricultural and food chemistry.

Biosynthesis of isocyanoterpenes in sponges

P. Scheuer, P. Karuso, 1989 .

Synthesis of Substituted Oxo-Azepines by Regio- and Diastereoselective Hydroxylation

Fei Liu, P. Karuso, H. Spedding, 2017, Molecules.

Diastereoselective Pictet–Spengler Reactions of a Tethered 2-Aminoimidazole

P. Karuso, S. Shengule, 2013 .

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

J. Jamie, Arthur James Cooper, P. Karuso, 2015, Neurochemical Research.

Ketimine reductase/CRYM catalyzes reductive alkylamination of α-keto acids, confirming its function as an imine reductase

J. Jamie, Arthur J. L. Cooper, Jason R Smith, 2015, Amino Acids.

Investigation of a coenzyme B12 model reaction by 13C NMR spectroscopy

J. Lally, H. Williams, P. Karuso, 1994 .

New Antimicrobial Bromotyrosine Analogues from the Sponge Pseudoceratina purpurea and Its Predator Tylodina corticalis

M. Gotsbacher, P. Karuso, 2015, Marine drugs.

Benzylic coupling constants [4J(MeCCH)] for a series of 4‐Methylbenzo[h]quinolines and 4‐Methylbenzo[h]quinolin‐2‐ones

P. Karuso, W. C. Taylor, 1986 .

Chemistry of sponges. VI: Scalarane sesterterpenes from Hyatella intestinalis

P. Karuso, B. Bowden, P. R. Bergquist, 1989 .

Timing and mechanistic implications of regiospecific carbonyl oxygen isotope exchange during vitamin B12 biosynthesis

B. Atshaves, H. Williams, M. Warren, 1991 .

Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads

M. Briggs, J. Williamson, P. Karuso, 2022, Marine drugs.

Crellasterones A and B: A-Norsterol Derivatives from the New Caledonian Sponge Crella incrustans

Andrew M. Piggott, P. Karuso, K. Ragini, 2017, Marine drugs.

Quality not Quantity: The Role of Marine Natural Products in Drug Discovery and Reverse Chemical Proteomics

Andrew M. Piggott, P. Karuso, 2005, Marine Drugs.

Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans

H. Kwon, P. Karuso, S. Cho, 2021, The Journal of Antibiotics.

Sphingomonas paucimobilis BPSI-3 mutant AN2 produces a red catabolite during biphenyl degradation

M. Gillings, D. Veal, A. Nouwens, 1999, Journal of Industrial Microbiology and Biotechnology.

Constituents of Eupomatia species. X. The synthesis of 6-Methoxy-5-methylbenzo[h]pyrrolo[4,3,2-de]quinolin-4(5H)-one (eupolauramine)

P. Karuso, W. C. Taylor, 1984 .

Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme

J. Fromont, P. Karuso, D. Jardine, 2001, Molecules.

Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display.

Andrew M. Piggott, R. Willows, P. Karuso, 2009, Bioorganic & medicinal chemistry.

Conformational Analysis of the cis‐ and trans‐Isomers of FK506 by NMR and Molecular Dynamics

P. Schmieder, H. Kessler, P. Karuso, 1991 .

9-Hydroxyfurodysinin-O-ethyl Lactone: A New Sesquiterpene Isolated from the Tropical Marine Sponge Dysidea arenaria

Andrew M. Piggott, P. Karuso, 2005, Molecules.

Is it time for artificial intelligence to predict the function of natural products based on 2D-structure.

E. Kellenberger, Fei Liu, R. Quinn, 2019, MedChemComm.

Rechoreographing Enterocin's Ballet of Isomers: Structure Revision of Enterocins C, D, and F.

Andrew M. Piggott, E. Lacey, P. Karuso, 2020, Organic Letters.

Nitrogenous bisabolene sesquiterpenes from marine invertebrates

J. Clardy, G. Duyne, P. Scheuer, 1986 .

Synergistic growth of two members from a mixed microbial consortium growing on biphenyl

D. Veal, P. Karuso, A. Davison, 1994 .

Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans

Hwa Jung Lee, H. Kwon, P. Karuso, 2021, The Journal of antibiotics.

The role of different structural motifs in the ultrafast dynamics of second generation protein stains.

A. Datta, P. Karuso, X. Franck, 2013, The journal of physical chemistry. B.

Chemistry of Sponges, III. Manoalide Monoacetate and Thorectolide Monoacetate, Two New Sesterter-penoids from Thorectandra excavatus

P. Karuso, P. R. Bergquist, R. C. Cambie, 1988 .

Biosynthetic studies of marine lipids. 20. Sequence of double-bond introduction in the sponge sterol 24.beta.-methylcholesta-5,7,22,25-tetraen-3.beta.-ol

C. Djerassi, P. Scheuer, P. Karuso, 1989 .

Long-chain α,ω-bisisothiocyanates from a marine sponge

P. Scheuer, P. Karuso, 1987 .

Secondary metabolites from Basotho medicinal plants. II. Bulbine capitata

P. Karuso, M. A. Qhotsokoane-Lusunzi, 2001 .

Epicocconone-Hemicyanine Hybrids: Near Infrared Fluorophores for Protein Staining and Cell Imaging.

P. Karuso, X. Franck, Philippe A. Peixoto, 2017, Chemistry.

Chemistry of Sponges, II. Pallescensone, A Furanosesquiterpenoid from Dictyodendrilla cavernosa

P. Karuso, P. R. Bergquist, R. C. Cambie, 1987 .

The Constituents of Marine Sponges. II. The Isolation From Aplysilla rosea (Dendroceratida) of (5R*,7S*,8R*,9S*,10R*,13S*,14S*,15S*)-15 ,17-Epoxy-17-Hydroxy-16-Oxospongian-7-Yl Butyrate (Aplyroseol-1) and Related Diterpenes (Aplyroseol-2 to Aplyroseol-6)

P. Karuso, W. C. Taylor, 1986 .

Real-time fluorescence monitoring of tryptic digestion in proteomics.

Angela S. Crawford, Graham B. I. Scott, D. Veal, 2008, Journal of proteome research.

A fluorescent natural product for ultra sensitive detection of proteins in one‐dimensional and two‐dimensional gel electrophoresis

Peter Karuso, Young-Ki Paik, Hung-Yoon Choi, 2003, Proteomics.

Rapid Identification of a Protein Binding Partner for the Marine Natural Product Kahalalide F by Using Reverse Chemical Proteomics

Andrew M. Piggott, P. Karuso, 2008, Chembiochem : a European journal of chemical biology.

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

J. Jamie, Arthur J. L. Cooper, P. Karuso, 2015, Neurochemical Research.

Site-directed mutagenesis and high-resolution NMR spectroscopy of the active site of porphobilinogen deaminase.

H. Williams, S. Grant, P. Karuso, 1988, Biochemistry.

Room Temperature Dual Fluorescence of a Locked GFP Chromophore Analogue.

P. Karuso, Ketan Ahire, Soumit Chatterjee, 2019, Journal of the American Chemical Society.

Excited state dynamics of brightly fluorescent second generation epicocconone analogues.

A. Datta, P. Karuso, X. Franck, 2015, The journal of physical chemistry. B.

Recombinant prespore-specific antigen from Dictyostelium discoideum is a beta-sheet glycoprotein with a spacer peptide modified by O-linked N-acetylglucosamine.

N. Packer, P. Curmi, A. Gooley, 1996, European journal of biochemistry.

Temporal resolution of the methylation sequence of vitamin B12 biosynthesis

H. Williams, P. Karuso, A. Scott, 1989 .

Mass spectrometric compatibility of Deep Purple and SYPRO Ruby total protein stains for high-throughput proteomics using large-format two-dimensional gel electrophoresis.

J. Skehel, M. Ball, P. Karuso, 2008, Rapid communications in mass spectrometry : RCM.

Design and synthesis of epicocconone analogues with improved fluorescence properties.

M. Ball, P. Cosette, P. Karuso, 2014, Journal of the American Chemical Society.

Mass spectral compatibility of four proteomics stains.

Peter Karuso, M. Ball, P. Karuso, 2007, Journal of proteome research.

Isolation and total synthesis of two novel metabolites from the fissurellid mollusc Scutus antipodes

P. Karuso, S. Chand, 2017 .

Rules for the addition of O-linked N-acetylglucosamine to secreted proteins in Dictyostelium discoideum--in vivo studies on glycosylation of mucin MUC1 and MUC2 repeats.

N. Packer, A. Gooley, K. Williams, 1998, European journal of biochemistry.

Mass spectrometric compatibility of Deep Purple and SYPRO Ruby total protein stains for high-throughput proteomics using large-format two-dimensional gel electrophoresis.

P. Karuso, Louisa Bill, Christina M. Nock, 2008, Rapid communications in mass spectrometry : RCM.

The chemical gymnastics of enterocin: evidence for stereodivergence in Nature.

Andrew M. Piggott, E. Lacey, A. Crombie, 2020, Organic & biomolecular chemistry.

Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion.

Peter Karuso, P. Karuso, Felix Cleemann, 2008, Analytical chemistry.

Synthesis of a new hydrophilic o-nitrobenzyl photocleavable linker suitable for use in chemical proteomics

Andrew M. Piggott, P. Karuso, 2005 .