S. Metkar

发表

M. Belting, R. Dressel, C. Menaa, 2005, Journal of Biological Chemistry.

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes

R. Gilbert, G. Anderluh, M. Pooga, 2014, Cell Death and Differentiation.

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.

J. Trapani, E. Podack, S. Raja, 2002, Immunity.

Interleukin-1R Signaling Is Essential for Induction of Proapoptotic CD8 T Cells, Viral Clearance, and Pathology during Lymphocytic Choriomeningitis Virus Infection in Mice

C. Borner, M. Simon, R. Wallich, 2012, Journal of Virology.

Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation.

R. Sanz-Pamplona, V. Moreno, G. Gil-Gómez, 2020, Cell reports.

NF‐κB protects from the lysosomal pathway of cell death

M. Peter, Justine C. Lee, D. Brömme, 2003, The EMBO Journal.

Circulating levels of TNFα and TNF receptor superfamily members in lymphoid neoplasia

K. Naresh, S. Metkar, V. Srinivas, 2000 .

Expression of Fas and Fas ligand in Hodgkin's disease.

K. Naresh, A. Redkar, S. Metkar, 1999, Leukemia and Lymphoma.

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis

C. Gabay, M. Simon, S. Sprague, 2017, Arthritis & rheumatology.

CD40 Ligand--an anti-apoptotic molecule in Hodgkin's disease.

K. Naresh, S. Metkar, S. Advani, 2001, Cancer biotherapy & radiopharmaceuticals.

Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent.

K. Naresh, S. Metkar, P. Manna, 2000, Experimental cell research.

CD40-ligation-mediated protection from apoptosis of a Fas-sensitive Hodgkin's-disease-derived cell line

K. Naresh, A. Redkar, S. Metkar, 1998, Cancer Immunology, Immunotherapy.

Perforin Rapidly Induces Plasma Membrane Phospholipid Flip-Flop

G. Anderluh, R. Gilbert, C. Froelich, 2011, PloS one.

Human neutrophils lack granzyme A, granzyme B, and perforin.

C. Froelich, S. Metkar, 2004, Blood.

to Cytolytic Proteins Killer Cell Cytotoxicity through Resistance Mediates Increased Resistance to Natural The Human Cytomegalovirus Protein UL16

L. Brandén, H. Browne, D. Cosman, 2014 .

The Human Cytomegalovirus Protein UL16 Mediates Increased Resistance to Natural Killer Cell Cytotoxicity through Resistance to Cytolytic Proteins

L. Brandén, H. Browne, D. Cosman, 2003, Journal of Virology.

Human and mouse granzyme A induce a proinflammatory cytokine response.

Lianfa Shi, M. Freudenberg, M. Simon, 2008, Immunity.

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

Yong J. Lee, S. Raja, C. Froelich, 2003, The Journal of cell biology.

Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH.

G. Anderluh, Z. Podlesek, C. Froelich, 2010, Molecular immunology.

Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.

V. Levitsky, B. Zuber, N. Ahlborg, 2005, Journal of immunological methods.

Intracellular trafficking of perforin: to thwart a killer.

C. Froelich, S. Metkar, 2011, Immunity.

Granzyme B-mediated apoptosis – the elephant and the blind men?

S. Raja, C. Froelich, S. Metkar, 2004, Cell Death and Differentiation.

Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.

S. Raja, C. Froelich, S. Metkar, 2003, Current opinion in immunology.

NF-kappaB protects from the lysosomal pathway of cell death.

M. Peter, Justine C. Lee, D. Brömme, 2003, The EMBO journal.

Granzyme A Produced by γ9δ2 T Cells Induces Human Macrophages to Inhibit Growth of an Intracellular Pathogen

C. Spencer, M. Xia, Guangyong Peng, 2013, PLoS pathogens.

Granzyme B translocates across the lipid membrane only in the presence of lytic agents.

G. Anderluh, C. Froelich, S. Metkar, 2008, Biochemical and biophysical research communications.

translocates across the lipid membrane onlyin the presence of lytic agents

G. Anderluh, C. Froelich, S. Metkar, 2008 .

Detection of functional cell surface perforin by flow cytometry.

C. Froelich, S. Metkar, Baikun Wang, 2005, Journal of immunological methods.

Flow cytometry cannot assess surface binding of perforin to target cells.

C. Froelich, S. Metkar, B. Wang, 2001, Blood.

Cytotoxic Cell Granule-mediated Apoptosis

Borries Demeler, Umesh R. Desai, Christopher J. Froelich, 2002, The Journal of Biological Chemistry.

Circulating levels of TNF alpha and TNF receptor superfamily members in lymphoid neoplasia.

K. Naresh, S. Metkar, V. Srinivas, 2000, American journal of hematology.

Lack of the CD8+ cell anti-HIV factor in CD8+ cell granules.

J. Levy, C. Froelich, S. Metkar, 2003, Blood.

Lack of the CD 8 cell anti-HIV factor in CD 8 cell granules

J. Levy, C. Froelich, S. Metkar, 2003 .

CHARACTERIZATION OF THE MACROMOLECULAR COMPLEX OF GRANZYME B WITH SERGLYCIN

U. Desai, S. Raja, C. Froelich, 2002 .

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

Yong J. Lee, S. Raja, C. Froelich, 2003, The Journal of cell biology.

Intracellular trafficking of perforin: to thwart a killer.

C. Froelich, S. Metkar, 2011, Immunity.