S. Earley

发表

Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide.

L. Nelin, L. Chicoine, S. Earley, 2002, Journal of applied physiology.

Critical Role for Transient Receptor Potential Channel TRPM4 in Myogenic Constriction of Cerebral Arteries

S. Earley, B. J. Waldron, J. Brayden, 2004, Circulation research.

TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries.

S. Earley, B. J. Waldron, J. Brayden, 2005, American journal of physiology. Heart and circulatory physiology.

Transient receptor potential channels and vascular function.

S. Earley, J. Brayden, 2010, Clinical science.

Endothelium-dependent Cerebral Artery Dilation Mediated by Transient Receptor Potential and Ca2+-activated K+ Channels

S. Earley, 2011, Journal of cardiovascular pharmacology.

Smooth Muscle Cell Ca2+: Think Locally, Act Globally

S. Earley, 2013, Microcirculation.

THESIS IN THE FACE OF HYPOXIA: MYOGLOBIN EXPRESSION UNDER HYPOXIC CONDTIONS IN CULTURED WEDDELL SEAL SKELETAL MUSCLE CELLS

S. Kanatous, M. Miranda, S. Earley, 2012 .

Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system.

C. Sigmund, Yumei Feng, S. Earley, 2017, American journal of physiology. Heart and circulatory physiology.

Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol

S. Parajuli, J. Malysz, S. Earley, 2013, Channels.

TRPM4 channels in smooth muscle function

S. Earley, 2013, Pflügers Archiv - European Journal of Physiology.

48-h Hypoxic exposure results in endothelium-dependent systemic vascular smooth muscle cell hyperpolarization.

S. Earley, B. Walker, J. Naik, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Endothelium-dependent blunting of myogenic responsiveness after chronic hypoxia.

S. Earley, B. Walker, 2002, American journal of physiology. Heart and circulatory physiology.

Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction.

S. Earley, B. Walker, 2003, American journal of physiology. Heart and circulatory physiology.

Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats.

L. Chicoine, S. Earley, B. Walker, 1999, American journal of physiology. Lung cellular and molecular physiology.

hypoxic rats does not cause myogenic vasoconstriction pulmonary arteries from control and chronically Pressure-induced smooth muscle cell depolarization in

L. Shimoda, S. Earley, B. Walker, 2015 .

Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction.

S. Earley, B. Walker, T. Resta, 2005, Journal of applied physiology.

TRPA1 channels in the vasculature

S. Earley, 2012, British journal of pharmacology.

Calcineurin/nuclear factor of activated T cells-coupled vanilliod transient receptor potential channel 4 ca2+ sparklets stimulate airway smooth muscle cell proliferation.

S. Earley, Albert L Gonzales, Limin Zhao, 2014, American journal of respiratory cell and molecular biology.

Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids

T. Murphy, S. Sandow, S. Earley, 2014, Pflügers Archiv - European Journal of Physiology.

Peripheral Coupling Sites Formed by STIM1 Govern the Contractility of Vascular Smooth Muscle Cells

Michael G. Alvarado, M. Trebak, S. Earley, 2021, bioRxiv.

Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation

A. Oulidi, F. Boop, Yumei Feng, 2015, Science Signaling.

Protein kinase C regulates vascular myogenic tone through activation of TRPM4.

S. V. Straub, S. Earley, J. Brayden, 2007, American journal of physiology. Heart and circulatory physiology.

CaV3.2 Channels and the Induction of Negative Feedback in Cerebral Arteries

E. Vigmond, A. Braun, B. Menon, 2014, Circulation research.

Local Regulation of Arterial L-Type Calcium Channels by Reactive Oxygen Species

S. Earley, G. Amberg, Stephanie A. Glapa, 2010, Circulation research.

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

S. Earley, P. Pires, Eun A Ko, 2017, The Journal of physiology.

A PLCγ1-Dependent, Force-Sensitive Signaling Network in the Myogenic Constriction of Cerebral Arteries

M. Nelson, Fabrice Dabertrand, D. Hill-Eubanks, 2014, Science Signaling.

(Sub)family feud: crosstalk between TRPC channels in vascular smooth muscle cells during vasoconstrictor agonist stimulation

S. Earley, Albert L Gonzales, Albert L. Gonzales, 2010, Journal of Physiology.

TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNELS, VASCULAR TONE AND AUTOREGULATION OF CEREBRAL BLOOD FLOW

M. Nelson, S. Earley, J. Brayden, 2008, Clinical and experimental pharmacology & physiology.

Protein kinase C regulates vascular myogenic tone through activation of TRPM 4

S. V. Straub, S. Earley, J. Brayden, 2007 .

Molecular diversity of receptor operated channels in vascular smooth muscle: a role for heteromultimeric TRP channels?

S. Earley, 2006, Circulation research.

of Cerebral Arteries Critical Role for Transient Receptor Potential Channel TRPM 4 in Myogenic Constriction

S. Earley, B. J. Waldron, J. Brayden, 2004 .

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

S. Earley, A. Greenstein, Pratish Thakore, 2019, Proceedings of the National Academy of Sciences.

TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure.

T. Pauyo, W. Liedtke, S. Earley, 2009, American journal of physiology. Heart and circulatory physiology.

No Static at All: Tuning Into the Complexities of Ca2+ Signaling in the Endothelium.

S. Earley, P. Pires, 2016, Circulation research.

Recruitment of Dynamic Endothelial Ca2+ Signals by the TRPA1 Channel Activator AITC in Rat Cerebral Arteries

Mark S Taylor, S. Earley, V. Solodushko, 2013, Microcirculation.

STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells

Michael G. Alvarado, M. Trebak, S. Earley, 2022, eLife.

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats.

S. Parajuli, J. Malysz, S. Earley, 2013, American journal of physiology. Renal physiology.

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology.

S. Parajuli, J. Malysz, S. Earley, 2013, American journal of physiology. Cell physiology.

Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries

S. Earley, Albert L Gonzales, Pratish Thakore, 2021, Function.

Central role of Ca2+-dependent regulation of vascular tone in vivo.

M. Nelson, S. Earley, 2006, Journal of applied physiology.

Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia.

A. Pastuszyn, S. Earley, B. Walker, 2003, American journal of physiology. Heart and circulatory physiology.

A TRPC3 signalling complex promotes cerebral artery remodelling during hypertension.

S. Earley, P. Pires, 2016, Cardiovascular research.

Redox regulation of transient receptor potential channels in the endothelium

S. Earley, P. Pires, 2017, Microcirculation.

Developmental differences in pulmonary eNOS expression in response to chronic hypoxia in the rat.

L. Nelin, L. Chicoine, S. Earley, 2002, Journal of applied physiology.

Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats.

L. Chicoine, S. Earley, B. Walker, 1999, American journal of physiology. Lung cellular and molecular physiology.

unaltered by nitric oxide Hypoxia-induced pulmonary endothelin-1 expression is

L. Nelin, L. Chicoine, J. Weaver, 2015 .

RESEARCH Integrative Cardiovascular Physiology and Pathophysiology Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system

C. Sigmund, Yumei Feng, S. Earley, 2018 .

STIM1 is the key that unlocks airway smooth muscle remodeling and hyperresponsiveness during asthma.

S. Earley, Pratish Thakore, P. Thakore, 2022, Cell calcium.

Estradiol attenuates hypoxia-induced pulmonary endothelin-1 gene expression.

S. Earley, T. Resta, 2002, American journal of physiology. Lung cellular and molecular physiology.

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.

S. Earley, P. Pires, M. Sullivan, 2015, American journal of physiology. Heart and circulatory physiology.

Defective Ca 2+ - dependent activation of TRPM4 channels contributes to age-related cerebral small vessel disease in Col4a1 mutant mice

M. Chaumeil, D. B. Gould, S. Earley, 2022 .

STIM 1-Dependent Peripheral Coupling Governs the Contractility of Vascular 4 Smooth Muscle Cells 5 6 7 8

Michael G. Alvarado, S. Earley, Albert L Gonzales, 2022 .

TRPM4 channels in smooth muscle function

S. Earley, 2013, Pflügers Archiv - European Journal of Physiology.

TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization.

S. Earley, M. Sullivan, 2013, American journal of physiology. Cell physiology.

and Experience-Dependent Regulation Superior Olive Activate TRP-Like Channels: Age- Metabotropic Glutamate Receptors in the Lateral

K. Kandler, A. Kalmbach, E. Vigmond, 2015 .

A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation

S. Earley, Albert L Gonzales, Albert L. Gonzales, 2010, Molecular Pharmacology.

Transient receptor potential channels in the vasculature.

S. Earley, J. Brayden, 2015, Physiological reviews.

Guidelines for the measurement of vascular function and structure in isolated arteries and veins.

J. Filosa, D. Gutterman, B. Isakson, 2021, American journal of physiology. Heart and circulatory physiology.

The intracellular Ca2+ release channel TRPML1 regulates lower urinary tract smooth muscle contractility

K. Sanders, Michael G. Alvarado, S. Earley, 2020, Proceedings of the National Academy of Sciences.

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility

K. Sanders, G. Hennig, S. Earley, 2017, Science Signaling.

TRPV4 Forms a Novel Ca2+ Signaling Complex With Ryanodine Receptors and BKCa Channels

M. Nelson, S. Earley, J. Brayden, 2005, Circulation research.

Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels

S. Earley, Albert L Gonzales, Albert L. Gonzales, 2009, Circulation research.

Neuron-Specific (Pro)renin Receptor Knockout Prevents the Development of Salt-Sensitive Hypertension

J. Grobe, Yumei Feng, A. Danser, 2014, Hypertension.

Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells.

C. Clay, S. Earley, M. Zhong, 2009, Cell calcium.

Transient Receptor Potential Channel Ankyrin 1: A Unique Regulator of Vascular Function

Michael G. Alvarado, S. Earley, P. Thakore, 2021, Cells.

Regulation of vascular tone by transient receptor potential ankyrin 1 channels.

S. Earley, Sher Ali, P. Thakore, 2020, Current topics in membranes.

The Physiological Sensor Channels TRP and Piezo: Nobel Prize in Physiology or Medicine 2021.

S. Earley, W. Lederer, L. F. Santana, 2022, Physiological reviews.

Optical Recording Reveals Novel Properties of GSK1016790A-Induced Vanilloid Transient Receptor Potential Channel TRPV4 Activity in Primary Human Endothelial Cells

S. Earley, Natalie L. Pitts, M. Sullivan, 2012, Molecular Pharmacology.

Vanilloid and Melastatin Transient Receptor Potential Channels in Vascular Smooth Muscle

S. Earley, 2010, Microcirculation.

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

S. Earley, P. Pires, Evan Yamasaki, 2018, Proceedings of the National Academy of Sciences.

Brain endothelial cell TRPA1 channels initiate neurovascular coupling

C. Tran, Michael G. Alvarado, B. Isakson, 2020, bioRxiv.

Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca2+‐Activated Cation Channels

S. Earley, Albert L. Gonzales, 2013, Microcirculation.

Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids

T. Murphy, S. Sandow, S. Earley, 2014, Pflügers Archiv - European Journal of Physiology.

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle.

S. Earley, Albert L. Gonzales, G. Amberg, 2010, American journal of physiology. Cell physiology.

Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells.

M. Tamkun, S. Earley, M. Leo, 2010, American journal of physiology. Cell physiology.

Isolation and Cannulation of Cerebral Parenchymal Arterioles.

Fabrice Dabertrand, S. Earley, P. Pires, 2016, Journal of visualized experiments : JoVE.

Endothelial cell TRPA1 activity exacerbates cerebral hemorrhage during severe hypertension

S. Earley, S. Alphonsa, Wencheng Li, 2023, Frontiers in Molecular Biosciences.

TRPML1 channels initiate Ca2+ sparks in vascular smooth muscle cells

K. Sanders, S. Earley, Bernard T. Drumm, 2020, Science Signaling.

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

S. Earley, P. Pires, 2018, eLife.

Transient Receptor Potential Channels and Endothelial Cell Calcium Signaling.

S. Earley, P. Thakore, 2019, Comprehensive Physiology.

Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries.

S. Earley, B. Walker, T. Resta, 2004, American journal of physiology. Heart and circulatory physiology.

Reply to Boedtkjer and Aalkjaer.

J. Filosa, D. Gutterman, B. Isakson, 2022, American journal of physiology. Heart and circulatory physiology.

Reply to De Mey et al.

J. Filosa, D. Gutterman, B. Isakson, 2022, American journal of physiology. Heart and circulatory physiology.

Robust Internal Elastic Lamina Fenestration in Skeletal Muscle Arteries

F. Dinenno, S. Earley, M. Sullivan, 2013, PloS one.

Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells

S. Earley, Albert L. Gonzales, Allison Bruhl, 2011, Channels.

Ca2+ release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells.

S. Earley, Albert L. Gonzales, G. Amberg, 2010, American journal of physiology. Cell physiology.

Ca 2 release from the sarcoplasmic reticulum is required for sustained TRPM 4 activity in cerebral artery smooth muscle cells

S. Earley, Albert L. Gonzales, G. Amberg, 2010 .

Dopaminergic Neurotoxicants Cause Biphasic Inhibition of Purinergic Calcium Signaling in Astrocytes

S. Earley, B. D. De Miranda, R. Tjalkens, 2014, PloS one.

Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice

M. Chaumeil, S. Earley, C. Labelle-Dumais, 2023, bioRxiv.

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

K. Sanders, Haifeng Zheng, T. Sung, 2018, Science Signaling.

Functional Significance of Transient Receptor Potential Channels in Vascular Function

S. Earley, J. Brayden, S. Reading, 2007 .

Pharmacological inhibition of TRPM 4 hyperpolarizes vascular smooth muscle

S. Earley, Albert L. Gonzales, G. Amberg, 2010 .

Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells.

S. Earley, Albert L. Gonzales, 2012, Cell calcium.

Vascular Mechanotransduction.

S. Chien, S. Earley, Yi-Shuan J. Li, 2023, Physiological reviews.

TRANSIENT RECEPTOR POTENTIAL CHANNELS IN THE VASCULATURE

S. Earley, J. Brayden, 2015 .

Differential Expression of Angiotensin II Type 1 Receptor Subtypes Within the Cerebral Microvasculature.

S. Earley, Evan Yamasaki, V. Krishnan, 2019, American journal of physiology. Heart and circulatory physiology.

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

S. Earley, P. Pires, 2018, eLife.

TRPs in the kidney – location, location, location

S. Earley, P. Pires, 2015, Acta physiologica.

Transient receptor potential channels in the vasculature.

S. Earley, J. Brayden, 2015, Physiological reviews.

Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca2+‐Activated Cation Channels

S. Earley, Albert L. Gonzales, 2013, Microcirculation.

TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization.

S. Earley, M. Sullivan, 2013, American journal of physiology. Cell physiology.

Optical Recording Reveals Novel Properties of GSK1016790A-Induced Vanilloid Transient Receptor Potential Channel TRPV4 Activity in Primary Human Endothelial Cells

S. Earley, Natalie L. Pitts, M. Sullivan, 2012, Molecular Pharmacology.

PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease

M. Chaumeil, S. Earley, Xiao Gao, 2023, Proceedings of the National Academy of Sciences of the United States of America.

PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease

M. Chaumeil, S. Earley, Xiao Gao, 2023, bioRxiv.

TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure.

T. Pauyo, W. Liedtke, S. Earley, 2009, American journal of physiology. Heart and circulatory physiology.

A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation

S. Earley, Albert L. Gonzales, Zarine I Garcia, 2010, Molecular Pharmacology.

Smooth Muscle Cell Ca2+: Think Locally, Act Globally

S. Earley, 2013, Microcirculation.

ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle

S. Ward, N. Leblanc, S. Earley, 2023, The Journal of general physiology.

TRPA1 channels in the vasculature

S. Earley, 2012, British journal of pharmacology.

PIP2 as the “coin of the realm” for neurovascular coupling

D. Kleinfeld, S. Earley, 2021, Proceedings of the National Academy of Sciences.