N. Jernigan

发表

Redox Regulation of Ion Channels and Receptors in Pulmonary Hypertension.

Laura Weise-Cross, T. Resta, N. Jernigan, 2019, Antioxidants & redox signaling.

Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension.

T. Resta, N. Jernigan, L. G. Gonzalez Bosc, 2017, Advances in experimental medicine and biology.

PICK1/calcineurin suppress ASIC1-mediated Ca2+ entry in rat pulmonary arterial smooth muscle cells.

T. Resta, N. Jernigan, L. G. Gonzalez Bosc, 2016, American journal of physiology. Cell physiology.

PICK 1 / Calcineurin Suppress ASIC 1-mediated Ca 2 + Entry in Rat Pulmonary Arterial Smooth Muscle Cells

T. Resta, N. Jernigan, Lindsay M. Herbert, 2015 .

Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling.

B. Walker, N. Kanagy, Laura Weise-Cross, 2020, American journal of respiratory cell and molecular biology.

Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2.

B. Broughton, B. Walker, T. Resta, 2013, Antioxidants & redox signaling.

Reduced membrane cholesterol after chronic hypoxia limits Orai1-mediated pulmonary endothelial Ca2+ entry.

B. Walker, T. Resta, N. Jernigan, 2018, American journal of physiology. Heart and circulatory physiology.

RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia.

T. Resta, N. Jernigan, Lindsay M. Herbert, 2018, American journal of physiology. Cell physiology.

Correlation of HO-1 expression with onset and reversal of hypoxia-induced vasoconstrictor hyporeactivity.

B. Walker, N. Jernigan, T. L. O'Donaughy, 2001, American journal of physiology. Heart and circulatory physiology.

Role of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension.

B. Walker, T. Resta, N. Jernigan, 2014, American journal of physiology. Heart and circulatory physiology.

Pathophysiology of Hypertension Role of ASIC 1 in the development of chronic hypoxia-induced pulmonary hypertension

B. Walker, T. Resta, N. Jernigan, 2013 .

Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling

T. Resta, N. Jernigan, Simin Yan, 2020, Antioxidants.

Reduced membrane cholesterol limits pulmonary endothelial Ca2+ entry after chronic hypoxia.

B. Walker, T. Resta, N. Jernigan, 2017, American journal of physiology. Heart and circulatory physiology.

hypoxic rats does not cause myogenic vasoconstriction pulmonary arteries from control and chronically Pressure-induced smooth muscle cell depolarization in

L. Shimoda, S. Earley, B. Walker, 2015 .

Role of acid-sensing ion channels in hypoxia- and hypercapnia-induced ventilatory responses

B. Walker, T. Resta, N. Jernigan, 2018, PloS one.

Loss of Acid-Sensing Ion Channel 2 Enhances Pulmonary Vascular Resistance and Hypoxic Pulmonary Hypertension.

B. Walker, T. Resta, N. Jernigan, 2019, Journal of applied physiology.

Myogenic vasoconstriction in mouse renal interlobar arteries: role of endogenous β and γENaC

H. Drummond, N. Jernigan, Nikki L. Jernigan, 2006 .

Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia.

B. Walker, T. Resta, N. Jernigan, 2004, American journal of physiology. Lung cellular and molecular physiology.

Chronic hypoxia augments protein kinase G-mediated Ca2+ desensitization in pulmonary vascular smooth muscle through inhibition of RhoA/Rho kinase signaling.

B. Walker, T. Resta, N. Jernigan, 2004, American journal of physiology. Lung cellular and molecular physiology.

Impaired pressure-induced constriction in mouse middle cerebral arteries of ASIC2 knockout mice.

H. Drummond, Kimberly P. Gannon, N. Jernigan, 2008, American journal of physiology. Heart and circulatory physiology.

Mechanisms of NFATc 3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle

J. Weaver, N. Jernigan, J. Ramiro-Diaz, 2014 .

Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle.

J. Weaver, N. Jernigan, L. G. Gonzalez Bosc, 2014, American journal of physiology. Cell physiology.

Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertension

Laura Weise-Cross, T. Resta, N. Jernigan, 2017, PloS one.

Enhanced NO-dependent pulmonary vasodilation limits increased vasoconstrictor sensitivity in neonatal chronic hypoxia.

B. Walker, Laura Weise-Cross, T. Resta, 2017, American journal of physiology. Heart and circulatory physiology.

smooth muscle following chronic hypoxia sensitization in pulmonary vascular 2+ kinase-induced Ca Reactive oxygen species mediate RhoA/Rho

B. Walker, T. Resta, N. Jernigan, 2016 .

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia.

B. Walker, T. Resta, N. Jernigan, 2008, American journal of physiology. Lung cellular and molecular physiology.

unaltered by nitric oxide Hypoxia-induced pulmonary endothelin-1 expression is

L. Nelin, L. Chicoine, J. Weaver, 2015 .

Acid‐sensing ion channel 1 contributes to pulmonary arterial smooth muscle cell depolarization following hypoxic pulmonary hypertension

T. Resta, N. Jernigan, J. Naik, 2021, The Journal of physiology.

ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.

B. Walker, T. Resta, N. Jernigan, 2009, American journal of physiology. Lung cellular and molecular physiology.

Augmented Pulmonary Vasoconstrictor Reactivity after Chronic Hypoxia Requires Src Kinase and Epidermal Growth Factor Receptor Signaling

B. Walker, Laura Weise-Cross, T. Resta, 2019 .

Actin polymerization contributes to enhanced pulmonary vasoconstrictor reactivity after chronic hypoxia.

B. Broughton, B. Walker, Laura Weise-Cross, 2018, American journal of physiology. Heart and circulatory physiology.

PKCβ and Reactive Oxygen Species Mediate Enhanced Pulmonary Vasoconstrictor Reactivity following Chronic Hypoxia in Neonatal Rats.

B. Walker, Laura Weise-Cross, T. Resta, 2020, American journal of physiology. Heart and circulatory physiology.

Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species.

B. Walker, N. Kanagy, T. Resta, 2011, Journal of applied physiology.

Contribution of oxygen radicals to altered NO-dependent pulmonary vasodilation in acute and chronic hypoxia.

B. Walker, T. Resta, N. Jernigan, 2004, American journal of physiology. Lung cellular and molecular physiology.

Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation.

T. Resta, N. Jernigan, Nikki L. Jernigan, 2002, American journal of physiology. Lung cellular and molecular physiology.

contractions in the rat main pulmonary artery Chronic hypoxia-induced spontaneous and rhythmic

R. Marthan, M. Oka, B. Walker, 2005 .

ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cells.

N. Jernigan, L. G. Gonzalez Bosc, Lindsay M. Herbert, 2016, American journal of physiology. Lung cellular and molecular physiology.

ASIC 1-mediated calcium entry stimulates NFATc 3 nuclear translocation via PICK 1 coupling in pulmonary arterial smooth muscle cells

N. Jernigan, Lindsay M. Herbert, C. Browning, 2016 .

Altered Lipid Domains Facilitate Enhanced Pulmonary Vasoconstriction Following Chronic Hypoxia.

B. Walker, Laura Weise-Cross, T. Resta, 2020, American journal of respiratory cell and molecular biology.

Altered Lipid Domains Facilitate Enhanced Pulmonary Vasoconstriction after Chronic Hypoxia

B. Walker, Laura Weise-Cross, T. Resta, 2020 .

Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension

T. Resta, N. Jernigan, L. G. Gonzalez Bosc, 2022, Frontiers in Molecular Biosciences.

Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle after chronic hypoxia.

B. Broughton, B. Walker, T. Resta, 2006, American journal of physiology. Lung cellular and molecular physiology.

Renal vascular responses to CORM-A1 in the mouse.

H. Drummond, D. Stec, J. Rimoldi, 2006, Pharmacological research.

Coupling of store-operated calcium entry to vasoconstriction is acid-sensing ion channel 1a dependent in pulmonary but not mesenteric arteries

B. Walker, T. Resta, N. Jernigan, 2020, PloS one.

Dietary salt enhances benzamil-sensitive component of myogenic constriction in mesenteric arteries.

H. Drummond, L. Galmiche, J. Granger, 2008, American journal of physiology. Heart and circulatory physiology.

Chronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle.

B. Walker, T. Resta, N. Jernigan, 2014, American journal of physiology. Lung cellular and molecular physiology.

Angiotensin II regulation of renal vascular ENaC proteins.

H. Drummond, J. Granger, N. Jernigan, 2009, American journal of hypertension.

Myogenic vasoconstriction in mouse renal interlobar arteries: role of endogenous beta and gammaENaC.

H. Drummond, N. Jernigan, Nikki L. Jernigan, 2006, American journal of physiology. Renal physiology.

Sensing tension: epithelial sodium channel/acid-sensing ion channel proteins in cardiovascular homeostasis.

H. Drummond, N. Jernigan, S. Grifoni, 2008, Hypertension.

A new trick for an old dogma: ENaC proteins as mechanotransducers in vascular smooth muscle.

H. Drummond, N. Jernigan, S. Grifoni, 2008, Physiology.

Vascular ENaC proteins are required for renal myogenic constriction.

H. Drummond, N. Jernigan, Nikki L. Jernigan, 2005, American journal of physiology. Renal physiology.

ASIC proteins regulate smooth muscle cell migration.

H. Drummond, N. Jernigan, S. Grifoni, 2008, Microvascular research.

Cholesterol Regulation of Pulmonary Endothelial Calcium Homeostasis.

B. Walker, T. Resta, N. Jernigan, 2018, Current topics in membranes.

Reactive oxygen species and RhoA signaling in vascular smooth muscle: role in chronic hypoxia-induced pulmonary hypertension.

B. Broughton, T. Resta, N. Jernigan, 2010, Advances in experimental medicine and biology.

Interleukin-6 trans-signaling contributes to chronic hypoxia-induced pulmonary hypertension

T. Howard, T. Resta, N. Jernigan, 2018, Pulmonary circulation.

Augmented pulmonary vasoconstrictor reactivity following chronic hypoxia requires Src kinase and EGFR signaling.

B. Walker, Laura Weise-Cross, T. Resta, 2019, American journal of respiratory cell and molecular biology.

Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation

T. Resta, N. Jernigan, J. Naik, 2022, The Journal of general physiology.

Smooth muscle acid‐sensing ion channel 1: pathophysiological implication in hypoxic pulmonary hypertension

N. Jernigan, Nikki L. Jernigan, 2015, Experimental physiology.

Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction.

B. Walker, T. Resta, N. Jernigan, 2012, American journal of physiology. Cell physiology.

GPER Contributes to the Development of Pulmonary Hypertension in Female Rats

E. Prossnitz, Laura Weise-Cross, T. Resta, 2020, The FASEB Journal.

Pulmonary PKG-1 is upregulated following chronic hypoxia.

B. Walker, T. Resta, N. Jernigan, 2003, American journal of physiology. Lung cellular and molecular physiology.

hypoxiaPKG-1 is upregulated following chronic

B. Walker, T. Resta, N. Jernigan, 2016 .

Membrane depolarization is required for pressure-dependent pulmonary arterial tone but not enhanced vasoconstriction to endothelin-1 following chronic hypoxia

B. Walker, T. Resta, N. Jernigan, 2020, Pulmonary circulation.

Calcium Homeostasis and Sensitization in Pulmonary Arterial Smooth Muscle

T. Resta, N. Jernigan, Nikki L. Jernigan, 2014, Microcirculation.

Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.

B. Broughton, B. Walker, T. Resta, 2010, American journal of physiology. Lung cellular and molecular physiology.