J. Weiss

发表

Modulation of mitochondrial function by endogenous Zn2+ pools

L. Kaczmarek, K. Gee, S. Sensi, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Estrogen-Receptor-Mediated Protection of Cerebral Endothelial Cell Viability and Mitochondrial Function after Ischemic Insult in vitro

Xue-jun Li, D. Krause, S. Duckles, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration

Sung Goan Ji, Y. V. Medvedeva, J. Weiss, 2019, Experimental Neurology.

N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture.

D. Choi, M. Goldberg, J. Weiss, 1987, The Journal of pharmacology and experimental therapeutics.

Mitochondrial Sequestration and Ca2+-Dependent Release of Cytosolic Zn2+ Loads in Cortical Neurons

S. Sensi, D. Ton-That, J. Weiss, 2002, Neurobiology of Disease.

Cortical neurones with Ca2+permeable AMPA/kainate channels display distinct receptor immunoreactivity and are GABAergic

D. Choi, D. Turetsky, J. Weiss, 1994, Neurobiology of Disease.

BMAA – an unusual cyanobacterial neurotoxin

J. Weiss, Kaivalya J Vyas, 2009, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Calcium, AMPA/Kainate Receptors, and Selective Neurodegeneration

J. Weiss, H. Yin, S. Carriedo, 1996 .

Differential Vulnerability to Excitatory Amino Acid-Induced Toxicity and Selective Neuronal Loss in Neurodegenerative Diseases

D. Choi, J. Weiss, 1991, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

A progressive translational mouse model of human valosin‐containing protein disease: The VCPR155H/+ mouse

V. Kimonis, J. Mukherjee, J. Vesa, 2013, Muscle & nerve.

Title A progressive translational mouse model of human valosin-containing protein disease : The VCP

V. Kimonis, J. Mukherjee, J. Vesa, 2013 .

Kainate injury to cultured basal forebrain cholinergic neurons is Ca2+ dependent

A. Lindsay, J. Weiss, H. Yin, 1994, Neuroreport.

Secobarbital Attenuates Excitotoxicity but Potentiates Oxygen—Glucose Deprivation Neuronal Injury in Cortical Cell Culture

R. Swanson, D. Choi, R. Giffard, 1993, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

AMPA/kainate receptor‐triggered Zn2+ entry into cortical neurons induces mitochondrial Zn2+ uptake and persistent mitochondrial dysfunction

S. Sensi, J. Weiss, H. Yin, 2000, The European journal of neuroscience.

Ca2+–Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration

S. Sensi, J. Weiss, John H Weiss, 2000, Trends in Neurosciences.

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

D. Choi, M. Goldberg, S. Sensi, 1994, Neurobiology of Disease.

Zn2+ permeates Ca2+permeable AMPA/kainate channels and triggers selective neural injury

J. Weiss, H. Yin, 1995, Neuroreport.

Ca2+-Permeable AMPA/Kainate and NMDA Channels: High Rate of Ca2+ Influx Underlies Potent Induction of Injury

J. Weiss, Y. Lu, H. Yin, 1996, The Journal of Neuroscience.

Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production.

S. Sensi, J. Weiss, H. Yin, 1999, Neuroreport.

Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production.

S. Sensi, S. Rao, J. Weiss, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Cultivating stem cells for treating amyotrophic lateral sclerosis.

J. Weiss, W. Loudon, S. Li, 2012, World journal of stem cells.

Calcium-permeable AMPA channels in neurodegenerative disease and ischemia

J. Weiss, S. Kwak, 2006, Current Opinion in Neurobiology.

Adenosine reduces cortical neuronal injury induced by oxygen or glucose deprivation in vitro

D. Choi, M. Goldberg, J. Weiss, 1988, Neuroscience Letters.

Beta-N-methylamino-L-alanine neurotoxicity: requirement for bicarbonate as a cofactor.

D. Choi, J. Weiss, 1988, Science.

Editorial: Excitotoxicity Turns 50. The Death That Never Dies

S. Sensi, J. Weiss, A. Granzotto, 2022, Frontiers in Neuroscience.

Intrathecal infusion of a Ca2+-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS

J. Weiss, H. Yin, D. Tang, 2007, Experimental Neurology.

Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord

J. Weiss, Cheng-I Hsu, H. Yin, 2014, Experimental Neurology.

Marked synergism between mutant SOD1 and glutamate transport inhibition in the induction of motor neuronal degeneration in spinal cord slice cultures

J. Weiss, H. Yin, 2012, Brain Research.

Zinc: new clues to diverse roles in brain ischemia.

C. Shuttleworth, J. Weiss, C. William Shuttleworth, 2011, Trends in pharmacological sciences.

Zn2+-induced disruption of neuronal mitochondrial function: Synergism with Ca2+, critical dependence upon cytosolic Zn2+ buffering, and contributions to neuronal injury

Sung Goan Ji, J. Weiss, 2018, Experimental Neurology.

Blockade of Ca2+-Permeable AMPA/Kainate Channels Decreases Oxygen–Glucose Deprivation-Induced Zn2+Accumulation and Neuronal Loss in Hippocampal Pyramidal Neurons

S. Sensi, J. Weiss, H. Yin, 2002, The Journal of Neuroscience.

Sensitive and selective detection of zinc ions in neuronal vesicles using PYDPY1, a simple turn-on dipyrrin.

J. Weiss, C. Frederickson, Yujiang Mei, 2011, Chemical communications.

Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neurons

J. Connor, C. Shuttleworth, J. Weiss, 2009, Neuroscience.

Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor

D. Prough, S. Lippard, S. Sensi, 2004, Journal of Neuroscience Methods.

Zinc and LTP

C. Christine, J. Weiss, J. Koh, 1989, Nature.

The Homozygote VCPR155H/R155H Mouse Model Exhibits Accelerated Human VCP-Associated Disease Pathology

R. Edwards, V. Kimonis, N. Khanlou, 2012, PloS one.

Rapid intra-mitochondrial Zn2+ accumulation in CA1 hippocampal pyramidal neurons after transient global ischemia: A possible contributor to mitochondrial disruption and cell death Short title: Mitochondrial Zn2+ accumulation after TGI

Sung Goan Ji, Y. V. Medvedeva, Y. Akbari, 2019 .

Rapid Intramitochondrial Zn2+ Accumulation in CA1 Hippocampal Pyramidal Neurons After Transient Global Ischemia: A Possible Contributor to Mitochondrial Disruption and Cell Death.

Sung Goan Ji, Y. V. Medvedeva, Y. Akbari, 2019, Journal of neuropathology and experimental neurology.

Cultured basal forebrain cholinergic neurons in contact with cortical cells display synapses, enhanced morphological features, and decreased dependence on nerve growth factor

R. Robertson, C. Ribak, J. Weiss, 1996, The Journal of comparative neurology.

The Homozygote VCPR155H/R155H Mouse Model Exhibits Accelerated Human VCP-Associated Disease Pathology

R. Edwards, V. Kimonis, N. Khanlou, 2012, PloS one.

Spinal cord neurons are vulnerable to rapidly triggered kainate neurotoxicity in vitro

A. Lindsay, J. Weiss, H. Yin, 1995, Brain Research.

Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice

V. Kimonis, J. Weiss, T. Mozaffar, 2012, Cell Death and Disease.

In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent

J. Weiss, H. Yin, S. Carriedo, 1995, Neuroreport.

Bicarbonate dependence of glutamate receptor activation by β-N-methylamino-l-alanine: Channel recording and study with related compounds

C. Christine, D. Choi, J. Weiss, 1989, Neuron.

A Sodium Zinc Exchange Mechanism Is Mediating Extrusion of Zinc in Mammalian Cells*

S. Sensi, I. Sekler, M. Hershfinkel, 2004, Journal of Biological Chemistry.

Extracellular Alkalinity Exacerbates Injury of Cultured Cortical Neurons

D. Choi, R. Giffard, J. Weiss, 1992, Stroke.

Tumor necrosis-factor-alpha (TNF-alpha) induces rapid insertion of Ca2+-permeable alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA)/kainate (Ca-A/K) channels in a subset of hippocampal pyramidal neurons.

J. Weiss, H. Yin, Y. Kuppumbatti, 2005, Experimental neurology.

Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration

Y. V. Medvedeva, J. Weiss, 2014, Neurobiology of Disease.

Preferential Zn 2 1 influx through Ca 2 1-permeable AMPA y kainate channels triggers prolonged mitochondrial superoxide production

S. Sensi, J. Weiss, H. Yin, 1999 .

Neurotoxicity of beta-N-methylamino-L-alanine (BMAA) and beta-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons.

D. Choi, J. Koh, J. Weiss, 1989, Brain research.

Mechanisms of seizure-induced ‘transcriptional channelopathy’ of hyperpolarization-activated cyclic nucleotide gated (HCN) channels

T. Baram, R. Bender, J. Weiss, 2008, Neurobiology of Disease.

AMPA Exposures Induce Mitochondrial Ca2+ Overload and ROS Generation in Spinal Motor Neurons In Vitro

S. Sensi, J. Weiss, H. Yin, 2000, The Journal of Neuroscience.

Mechanisms of Rapid Reactive Oxygen Species Generation in Response to Cytosolic Ca2+ or Zn2+ Loads in Cortical Neurons

Sung Goan Ji, J. Weiss, Aaron Clausen, 2013, PloS one.

Intracellular Zn2+ Accumulation Contributes to Synaptic Failure, Mitochondrial Depolarization, and Cell Death in an Acute Slice Oxygen–Glucose Deprivation Model of Ischemia

B. Lin, C. Shuttleworth, Y. V. Medvedeva, 2009, The Journal of Neuroscience.

Rapid Ca2+ Entry through Ca2+-Permeable AMPA/Kainate Channels Triggers Marked Intracellular Ca2+Rises and Consequent Oxygen Radical Production

S. Sensi, J. Weiss, H. Yin, 1998, The Journal of Neuroscience.

Tumor necrosis-factor-alpha (TNF-α) induces rapid insertion of Ca2+-permeable α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA)/kainate (Ca-A/K) channels in a subset of hippocampal pyramidal neurons

J. Weiss, H. Yin, Y. Kuppumbatti, 2005, Experimental Neurology.

Heterogeneity of Ca2+-Permeable AMPA/Kainate Channel Expression in Hippocampal Pyramidal Neurons: Fluorescence Imaging and Immunocytochemical Assessment

J. Weiss, Fumio Ogoshi, 2003, The Journal of Neuroscience.

Dendritic localization of Ca2+‐permeable AMPA/kainate channels in hippocampal pyramidal neurons

S. Sensi, J. Weiss, H. Yin, 1999 .

cultured murine hippocampal neurones currents are mediated by calcium-permeable AMPA/kainate channels in

S. Sensi, Yousheng Jia, J. Weiss, 2008 .

BMAA selectively injures motor neurons via AMPA/kainate receptor activation

Paul Alan Cox, P. Cox, J. Weiss, 2006, Experimental Neurology.

Zn2+ currents are mediated by calcium‐permeable AMPA/Kainate channels in cultured murine hippocampal neurones

S. Sensi, Yousheng Jia, J. Weiss, 2002, The Journal of physiology.

Ca2+–Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration

S. Sensi, J. Weiss, 2000, Trends in Neurosciences.

Kainate-stimulated Zn2+ uptake labels cortical neurons with Ca2+-permeable AMPA/kainate channels

J. Weiss, H. Yin, S. Carriedo, 1998, Brain Research.

Motor Neurons Are Selectively Vulnerable to AMPA/Kainate Receptor-Mediated Injury In Vitro

J. Weiss, H. Yin, S. Carriedo, 1996, The Journal of Neuroscience.

Ca2+ permeable AMPA/kainate channels permit rapid injurious Ca2+ entry.

J. Weiss, H. Yin, Y. Lu, 1995 .

Ca2+ and in vitro kainate damage to cortical and hippocampal SMI-32(+) neurons.

J. Weiss, H. Yin, S. J. Burke, 1995, NeuroReport.

Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity

D. Choi, J. Weiss, H. Yin, 1994, Neuroscience.

Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes.

K. Gee, S. Sensi, D. Ton-That, 2002, Cell calcium.

Zn(2+): a novel ionic mediator of neural injury in brain disease.

J. Koh, S. Sensi, J. Weiss, 2000, Trends in pharmacological sciences.

AMPA receptor activation potentiates zinc neurotoxicity

D. Choi, J. Koh, D. Hartley, 1993, Neuron.

Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer.

H. Friess, K. Ketterer, M. Büchler, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Carnosine as a modulator of endogenous Zn2+ effects

J. Koh, S. Sensi, J. Weiss, 2001 .

A new mitochondrial fluorescent zinc sensor.

K. Gee, S. Sensi, D. Ton-That, 2003, Cell calcium.

17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion.

Xuejun Li, D. Krause, S. Duckles, 2012, Free radical biology & medicine.

Training stem cells for treatment of malignant brain tumors.

J. Weiss, W. Loudon, S. Li, 2014, World journal of stem cells.

Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome

D. Wallace, V. Kimonis, V. Procaccio, 2011, Neuroscience Letters.

Rapid Communication: Ca2+ Channel Blockers Attenuate β‐Amyloid Peptide Toxicity to Cortical Neurons in Culture

C. Cotman, C. Pike, J. Weiss, 1994 .

Zn2+ Induces Permeability Transition Pore Opening and Release of Pro-apoptotic Peptides from Neuronal Mitochondria*

O. Steward, D. Jiang, S. Sensi, 2001, The Journal of Biological Chemistry.

Neurotoxicity ofβ-N-methylamino-l-alanine (BMAA) andβ-N-oxalylamino-l-alamine (BOAA) on cultured cortical neurons

D. Choi, J. Koh, J. Weiss, 1989, Brain Research.

Glutamate Neurotoxicity, Calcium, and Zinc a

C. Christine, D. Choi, J. Weiss, 1989, Annals of the New York Academy of Sciences.

Enhanced survival and morphological features of basal forebrain cholinergic neurons in vitro: Role of neurotrophins and other potential cortically derived cholinergic trophic factors

R. Robertson, J. Weiss, D. Ha, 1999, The Journal of comparative neurology.

The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction

I. Reynolds, E. Aizenman, J. Weiss, 2021, Biomedicines.

Contributions of Ca2+ and Zn2+ to spreading depression‐like events and neuronal injury

C. Shuttleworth, J. Weiss, R. Dietz, 2009, Journal of neurochemistry.

Ca2+ Permeable AMPA Channels in Diseases of the Nervous System

J. Weiss, 2011, Front. Mol. Neurosci..

Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis

J. Weiss, Shyam D. Rao, 2004, Trends in Neurosciences.

Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall

P. Schwartz, Zhiwei Ma, Q. Lu, 2012, Cancer Cell International.

Title Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall Permalink

P. Schwartz, Zhiwei Ma, Q. Lu, 2012 .

Disruption of Glial Glutamate Transport by Reactive Oxygen Species Produced in Motor Neurons

J. Weiss, John H Weiss, Shyam D Rao, 2003, The Journal of Neuroscience.

Ca2+ Permeable AMPA Channels in Diseases of the Nervous System

J. Weiss, 2011, Front. Mol. Neurosci..

TNF-α triggers rapid membrane insertion of Ca2+ permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury

L. Sorkin, J. Weiss, Shyam D. Rao, 2012, Experimental Neurology.

Zn2+ Influx Is Critical for Some Forms of Spreading Depression in Brain Slices

C. Shuttleworth, J. Weiss, R. Dietz, 2008, The Journal of Neuroscience.

Mitochondrial Zn2+ Accumulation: A Potential Trigger of Hippocampal Ischemic Injury

Sung Goan Ji, Y. V. Medvedeva, J. Weiss, 2019, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Dendritic localization of Ca(2+)-permeable AMPA/kainate channels in hippocampal pyramidal neurons.

S. Sensi, J. Weiss, H. Yin, 1999, The Journal of comparative neurology.

17 β -Estradiol prevents cell death and mitochondrial dysfunction by estrogen receptor-dependent mechanism in astrocytes following oxygen-glucose deprivation/reperfusion

D. Krause, S. Duckles, J. Weiss, 2013 .

Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.

C. Cotman, C. Pike, J. Weiss, 1994, Journal of neurochemistry.

Cortical neurons containing somatostatin‐ or parvalbumin‐like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro

D. Choi, K. Baimbridge, J. Weiss, 1990, Neurology.

The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity.

D. Choi, J. Koh, D. Hartley, 1990, Science.

Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria

Sung Goan Ji, Y. V. Medvedeva, J. Weiss, 2017, The Journal of Neuroscience.

Ketamine protects cultured neocortical neurons from hypoxic injury

D. Choi, M. Goldberg, J. Weiss, 1986, Brain Research.

Inflammation-induced GluA1 trafficking and membrane insertion of Ca2+ permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A

Adam R Ferguson, L. Sorkin, C. Svensson, 2017, Experimental Neurology.

Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord

D. Fischer, H. Keirstead, G. Nistor, 2010, PloS one.

VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy

K. Palczewski, V. Kimonis, J. Weiss, 2022, Journal of Translational Medicine.

Zn2+ chelation improves recovery by delaying spreading depression-like events

Russell E. Carter, C. Shuttleworth, J. Weiss, 2010, Neuroreport.

Cholinergic neurons from different subdivisions of the basal forebrain lack connectional specificity for cerebral cortical target sites in vitro.

R. Robertson, J. Baratta, J. Weiss, 1996, Brain research. Developmental brain research.

A molecular jigsaw puzzle.

References, C. Heeger, Shirakawa, 2017, Nature materials.

Distinctive Morphological Features of a Subset of Cortical Neurons Grown in the Presence of Basal Forebrain Neurons In Vitro

R. Robertson, J. Weiss, D. Ha, 1998, The Journal of Neuroscience.

Slow non-NMDA receptor mediated neurotoxicity and amyotrophic lateral sclerosis.

D. Choi, J. Weiss, 1991, Advances in neurology.

Differential vulnerability of CA1 vs CA3 pyramidal neurons after ischemia: possible relationship to sources of Zn2+ accumulation and its entry into and prolonged effects on mitochondria.

Sung Goan Ji, Y. V. Medvedeva, J. Weiss, 2016, The Journal of neuroscience : the official journal of the Society for Neuroscience.

AMPA/kainate receptor-mediated damage to NADPH-diaphorase-containing neurons is Ca2+ dependent

D. Choi, D. Turetsky, J. Weiss, 1994, Neuroscience Letters.

Mechanisms of seizure-induced ‘transcriptional channelopathy’ of hyperpolarization-activated cyclic nucleotide gated (HCN) channels

T. Baram, R. Bender, J. Weiss, 2008, Neurobiology of Disease.

Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration

Y. V. Medvedeva, J. Weiss, 2014, Neurobiology of Disease.