David K. Leahy

发表

Evaluating the Impact of a Decade of Funding from the Green Chemistry Institute Pharmaceutical Roundtable

Stefan G. Koenig, David K. Leahy, Andrew S. Wells, 2018, Organic Process Research & Development.

Design and evolution of the BMS process greenness scorecard

David K. Leahy, Victor Hung, Melanie M. Miller, 2017 .

Inspiring process innovation via an improved green manufacturing metric: iGAL

John D. Hayler, Ulrich Scholz, Stefan G. Koenig, 2018 .

The PMI Predictor app to enable green-by-design chemical synthesis

Jun Li, Stefan G. Koenig, David K. Leahy, 2019, Nature Sustainability.

A Pharmaceutical Industry Perspective on Sustainable Metal Catalysis

John D. Hayler, David K. Leahy, Eric M. Simmons, 2018, Organometallics.

Preparation of Phosphonooxymethyl Prodrugs of HIV-1 Attachment Inhibitors

David K. Leahy, Shawn K. Pack, S. K. Pack, 2013 .

A deeper shade of green: inspiring sustainable drug manufacturing

John D. Hayler, Stefan G. Koenig, David K. Leahy, 2017 .

Seven Important Elements for an Effective Green Chemistry Program: An IQ Consortium Perspective

David K. Leahy, Peter J. Dunn, Michael E. Kopach, 2013 .

Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12

David K. Leahy, R. Sheldon, J. Hayler, 2021, ACS Sustainable Chemistry & Engineering.

Shielding Effect of Nanomicelles: Stable and Catalytically Active Oxidizable Pd(0) Nanoparticle Catalyst Compatible for Cross-Couplings of Water-Sensitive Acid Chlorides in Water

Andrew J. Wilson, David K. Leahy, J. Jasinski, 2021, JACS Au.

Development of Two Complementary Syntheses for a Privileged CGRP Receptor Antagonist Substructure

David K. Leahy, Sundaramurthy Rangaswamy, L. V. Desai, 2012 .

Development of an Efficient Synthesis of Two CRF Antagonists for the Treatment of Neurological Disorders

David K. Leahy, B. Su, Jason Zhu, 2010 .

Catalytic asymmetric and stereodivergent oligonucleotide synthesis

David K. Leahy, Scott J. Miller, Yongseok Kwon, 2020, Science.

The PMI Predictor - a Web App Enabling Green-by-Design Chemical Synthesis

David K. Leahy, Martin D. Eastgate, J. Gage, 2019 .

Stereodivergent construction of cyclic ethers by a regioselective and enantiospecific rhodium-catalyzed allylic etherification: total synthesis of gaur acid.

David K. Leahy, W. J. Andrews, P. Evans, 2004, Angewandte Chemie.

Regioselective and Enantiospecific Rhodium-Catalyzed Intermolecular Allylic Etherification with Ortho-Substituted Phenols

David K. Leahy, P. and, 2000 .

Regioselective and enantiospecific rhodium-catalyzed allylic alkylation reactions using copper(I) enolates: synthesis of (-)-sugiresinol dimethyl ether.

David K. Leahy, P. Evans, 2003, Journal of the American Chemical Society.

Development of a Scalable Synthesis of the Small Molecule TGFβR1 Inhibitor BMS-986260

David K. Leahy, Martin D. Eastgate, A. Mathur, 2020 .

Rhodium(I)‐Catalyzed Allylic Substitution Reactions and Their Applications to Target Directed Synthesis

David K. Leahy, P. Evans, 2005 .

Control Strategy for the Manufacture of Brivanib Alaninate, a Novel Pyrrolotriazine VEGFR/FGFR Inhibitor

David K. Leahy, Sushil K. Srivastava, T. LaPorte, 2015 .

Stereodivergent construction of cyclic ethers by a regioselective and enantiospecific rhodium-catalyzed allylic etherification: total synthesis of gaur acid.

David K. Leahy, W. J. Andrews, P. Evans, 2004, Angewandte Chemie.

Development of a scalable palladium-catalyzed α-arylation process for the synthesis of a CGRP antagonist

David K. Leahy, M. Hay, Y. Hsiao, 2013 .

Scalable α-Arylation of Nitriles in Aqueous Micelles using Ultrasmall Pd Nanoparticles: Surprising Formation of Carbanions in Water

David K. Leahy, J. Jasinski, P. Bora, 2020 .

Beyond organic solvents: synthesis of a 5-HT4 receptor agonist in water

David K. Leahy, M. Stirling, J. Bailey, 2021, Green Chemistry.

Bisulfite Addition Compounds as Substrates for Reductive Aminations in Water.

David K. Leahy, Xiaohan Li, B. Lipshutz, 2021, Organic letters.

Metal–Micelle Cooperativity: Phosphine Ligand-Free Ultrasmall Palladium(II) Nanoparticles for Oxidative Mizoroki–Heck-type Couplings in Water at Room Temperature

David K. Leahy, J. Jasinski, Sachin Handa, 2021, JACS Au.

Regio- and enantiospecific rhodium-catalyzed allylic etherification reactions using copper(I) alkoxides: influence of the copper halide salt on selectivity.

David K. Leahy, P. Evans, 2002, Journal of the American Chemical Society.

Determination of the Relative Stability of a Multipolymorph System via a Novel Pure Component Free Energy Calculation

David K. Leahy, D. Erdemir, Jun Li, 2012 .

Catalytic Sulfamoylation of Alcohols with Activated Aryl Sulfamates.

David K. Leahy, Scott J. Miller, Naoko Ichiishi, 2019, Organic letters.

Trichloromethyl Carbanion in Aqueous Micelles: Mechanistic Insights and Access to Carboxylic Acids from (Hetero)aryl Halides

David K. Leahy, S. Hazra, Frederick A. Hicks, 2022, ACS Catalysis.

Efficient and scalable enantioselective synthesis of a CGRP antagonist.

David K. Leahy, R. Hanson, M. Sugiyama, 2012, Organic letters.

Halide ion effects in the rhodium-catalyzed allylic substitution reaction using copper(I) alkoxides and enolates

David K. Leahy, P. Evans, Laura M. Slieker, 2003 .

Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.

David K. Leahy, J. Barrish, M. Kirby, 2017, Journal of medicinal chemistry.

Regio- and enantiospecific rhodium-catalyzed allylic etherification reactions using copper(I) alkoxides: influence of the copper halide salt on selectivity.

David K. Leahy, P. Evans, 2002, Journal of the American Chemical Society.