W. Wende

发表

STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA

Wolfgang Wende, Iddo Heller, Gerrit Sitters, 2013, Nature Methods.

Sliding and jumping of single EcoRV restriction enzymes on non-cognate DNA

Alfred Pingoud, Wolfgang Wende, Claude Loverdo, 2008, Nucleic acids research.

Analysis of the mechanism of the Serratia nuclease using site-directed mutagenesis.

A. Pingoud, P. Friedhoff, W. Wende, 1996, Nucleic acids research.

Type II restriction endonucleases—a historical perspective and more

Alfred Pingoud, Wolfgang Wende, Geoffrey G. Wilson, 2014, Nucleic acids research.

Type II restriction endonucleases — a historical perspective and more

A. Pingoud, G. Wilson, W. Wende, 2016, Nucleic acids research.

The Mechanism of DNA Cleavage by the Type II. Restriction Enzyme EcoRV: Asp36 Is Not Directly Involved in DNA Cleavage but Serves to Couple Indirect. Readout to Catalysis

A. Jeltsch, A. Pingoud, F. Stahl, 1998, Biological chemistry.

Developing a programmed restriction endonuclease for highly specific DNA cleavage

A. Jeltsch, A. Pingoud, V. Pingoud, 2005, Nucleic acids research.

From monomeric to homodimeric endonucleases and back: engineering novel specificity of LAGLIDADG enzymes.

Alfred Pingoud, Wolfgang Wende, Marlene Belfort, 2006, Journal of molecular biology.

Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats

A. Pingoud, P. Friedhoff, W. Wende, 2013, Nucleic acids research.

Generation of Novel Nucleases with Extended Specificity by Rational and Combinatorial Strategies

A. Pingoud, W. Wende, 2011, Chembiochem : a European journal of chemical biology.

A. Pingoud, P. Friedhoff, W. Wende, 1999, Nature Structural Biology.

Photocaged variants of the MunI and PvuII restriction enzymes.

A. Pingoud, V. Šikšnys, C. Urbanke, 2011, Biochemistry.

Photocross-linking of the Homing Endonuclease PI-SceI to Its Recognition Sequence*

A. Pingoud, V. Pingoud, F. Christ, 1999, The Journal of Biological Chemistry.

Structural and functional analysis of the homing endonuclease PI-sceI by limited proteolytic cleavage and molecular cloning of partial digestion products.

A. Pingoud, V. Pingoud, H. Thole, 1998, Biochemistry.

Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI.

A. Pingoud, V. Pingoud, F. Christ, 1996, Nucleic acids research.

The monomeric homing endonuclease PI‐SceI has two catalytic centres for cleavage of the two strands of its DNA substrate

A. Pingoud, V. Pingoud, F. Christ, 1999, The EMBO journal.

A Mutational Analysis of DNA Binding and Cleavage by the Homing Endonuclease PI-SceI

A. Pingoud, V. Pingoud, F. Christ, 2000, Molecular Biology.

Editorial: Alfred Pingoud (1945–2015)

B. Stoddard, A. Jeltsch, P. Friedhoff, 2015, Nucleic acids research.

Determination of the DNA bend angle induced by the restriction endonuclease EcoRV in the presence of Mg2+.

A. Pingoud, W. Wende, U. Fagin, 1993, The Journal of biological chemistry.

DNA Recognition by the Homing Endonuclease PI-SceI Involves a Divalent Metal Ion Cofactor-induced Conformational Change*

A. Pingoud, W. Wende, A. Noël, 2004, Journal of Biological Chemistry.

A model for the PI-SceIxDNA complex based on multiple base and phosphate backbone-specific photocross-links.

A. Pingoud, V. Pingoud, F. Christ, 2000, Journal of molecular biology.

The production and characterization of artificial heterodimers of the restriction endonuclease EcoRV.

A. Pingoud, F. Stahl, W. Wende, 1996, Biological chemistry.

Peculiarities of the interaction of the restriction endonuclease BspD6I with DNA containing its recognition site.

T. Hianik, T. Oretskaya, E. Kubareva, 2016, Biochimica et biophysica acta.

High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI.

U. Heinemann, A. Pingoud, Erik Werner, 2002, Nucleic acids research.

Redesigning the single‐chain variant of the restriction endonuclease PvuII by circular permutation

A. Pingoud, W. Wende, B. Schierling, 2012, FEBS letters.

Protein engineering of the restriction endonuclease EcoRV: replacement of an amino acid residue in the DNA binding site leads to an altered selectivity towards unmodified and modified substrates.

A. Jeltsch, A. Pingoud, W. Wende, 1994, Biochimica et biophysica acta.

Identification of Asp218 and Asp326 as the principal Mg2+ binding ligands of the homing endonuclease PI-SceI.

A. Pingoud, V. Pingoud, W. Wende, 2000, Biochemistry.

[Analysis of binding and cleavage of DNA by the gene conversion PI-SCEI endonuclease using site-directed mutagenesis].

A. Pingoud, V. Pingoud, F. Christ, 2000, Молекулярная биология.

A procedure for renaturation and purification of the extracellular Serratia marcescens nuclease from genetically engineered Escherichia coli.

C Urbanke, W Wende, A. Pingoud, 1994, Protein expression and purification.

Synthesis and DNA Cleavage Activity of Bis‐3‐chloropiperidines as Alkylating Agents

B. Gatto, A. Pingoud, W. Wende, 2014, ChemMedChem.

Controlling the enzymatic activity of a restriction enzyme by light

B. Spengler, A. Pingoud, M. Kokkinidis, 2009, Proceedings of the National Academy of Sciences.

Precision Genome Surgery with Meganucleases: A Promising Biopharmaceutical for Gene Therapy

George H. Silva, A. Pingoud, W. Wende, 2013 .

Type II restriction endonucleases: structure and mechanism

A. Pingoud, M. Fuxreiter, V. Pingoud, 2005, Cellular and Molecular Life Sciences.

On the divalent metal ion dependence of DNA cleavage by restriction endonucleases of the EcoRI family.

A. Jeltsch, A. Pingoud, M. Fuxreiter, 2009, Journal of molecular biology.

In vivo genome editing as a potential treatment strategy for inherited retinal dystrophies

B. Lorenz, K. Stieger, W. Wende, 2017, Progress in Retinal and Eye Research.

Progress in Retinal and Eye Research

B. Lorenz, K. Stieger, W. Wende, 2022 .

Chimeras of the Homing Endonuclease PI‐SceI and the Homologous Candida tropicalis Intein: A Study to Explore the Possibility of Exchanging DNA‐Binding Modules to Obtain Highly Specific Endonucleases with Altered Specificity

A. Pingoud, V. Pingoud, W. Wende, 2004, Chembiochem : a European journal of chemical biology.

TALE-PvuII Fusion Proteins – Novel Tools for Gene Targeting

A. Pingoud, T. Cathomen, T. Lahaye, 2013, PloS one.

A novel zinc-finger nuclease platform with a sequence-specific cleavage module

Alfred Pingoud, Wolfgang Wende, Toni Cathomen, 2011, Nucleic acids research.

Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments

B. Lorenz, K. Stieger, W. Wende, 2018, Molecular therapy. Nucleic acids.

High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-Sce

U. Heinemann, A. Pingoud, I. Werner, 2002 .

Plasmodium falciparum glutathione S‐transferase—Structural and mechanistic studies on ligand binding and enzyme inhibition

Wolfgang Wende, K. Fritz-Wolf, K. Becker, 2006, Protein science : a publication of the Protein Society.

Novel missense mutation in the EDA gene in a family affected by oligodontia

S. Ruf, W. Wende, N. Bock, 2016, Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.

Mechanism and Regulation of Co-transcriptional mRNP Assembly and Nuclear mRNA Export.

P. Friedhoff, W. Wende, K. Sträßer, 2019, Advances in experimental medicine and biology.

A sliding restriction enzyme pauses.

A. Pingoud, W. Wende, 2007, Structure.

Homing Endonucleases: Tools and Targets for Protein Engineering

A. Pingoud, V. Pingoud, W. Wende, 2003 .

A new strategy of positioning and detecting DNA in protein DNA

O. Bénichou, R. Voituriez, C. Loverdo, 2008 .

The rotation-coupled sliding of EcoRV

A. Pingoud, M. Kokkinidis, Carolin Menges, 2012, Nucleic acids research.

Engineering novel restriction endonucleases: principles and applications.

W Wende, A. Jeltsch, A. Pingoud, 1996, Trends in biotechnology.

Restriction endonuclease SsoII with photoregulated activity--a "molecular gate" approach.

A. Pingoud, T. Oretskaya, E. Kubareva, 2011, Bioconjugate chemistry.

Comparison of N-terminal affinity fusion domains: effect on expression level and product heterogeneity of recombinant restriction endonuclease EcoRV

U. Rinas, A. Pingoud, W. Wende, 1994, Applied Microbiology and Biotechnology.

Biochemical and molecular characterization of a restriction endonuclease Tvu2HI from Thermoactinomyces vulgaris 2H and study of its R-M system.

R. Roberts, W. Wende, F. Limam, 2020, International journal of biological macromolecules.

Tracking of single quantum dot labeled EcoRV sliding along DNA manipulated by double optical tweezers.

A. Pingoud, W. Wende, A. Biebricher, 2009, Biophysical journal.

Novel missense mutation in the EDA gene in a family affected by oligodontia

S. Ruf, W. Wende, N. Bock, 2016, Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.

Identification of conserved Features of Laglidadg Homing endonucleases

Wolfgang Wende, Sergei A. Spirin, Alexander Grishin, 2010, J. Bioinform. Comput. Biol..

Intra- vs intersubunit communication in the homodimeric restriction enzyme EcoRV: Thr 37 and Lys 38 involved in indirect readout are only important for the catalytic activity of their own subunit.

A. Jeltsch, A. Pingoud, W. Wende, 1998, Biochemistry.

Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein.

A. Jeltsch, A. Pingoud, W. Wende, 1996, Proceedings of the National Academy of Sciences of the United States of America.

High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.

J. Otero, A. Pingoud, M. V. van Raaij, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

The protein splicing domain of the homing endonuclease PI-sceI is responsible for specific DNA binding.

A. Pingoud, V. Pingoud, W. Wende, 1998, Nucleic acids research.

Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases

Alfred Pingoud, Wolfgang Wende, Ute Curth, 2011, Nucleic acids research.

Synthesis and DNA Cleavage Activity of Bis‐3‐chloropiperidines as Alkylating Agents

B. Gatto, A. Pingoud, W. Wende, 2014, ChemMedChem.