A. Llebaria

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Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors

J. Giraldo, J. Pin, X. Rovira, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

An allosteric modulator to control endogenous G protein-coupled receptors with light.

P. Gorostiza, J. Giraldo, J. Pin, 2014, Nature chemical biology.

Correction: Photoswitchable dynasore analogs to control endocytosis with light

E. Giralt, J. Hernando, P. Gorostiza, 2020, Chemical science.

Mechanistic Insights into Light-Driven Allosteric Control of GPCR Biological Activity.

Alice E. Berizzi, C. Goudet, X. Rovira, 2020, ACS pharmacology & translational science.

Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology

Kira E. Poskanzer, G. Perea, P. Gorostiza, 2019, Proceedings of the National Academy of Sciences.

GPCR photopharmacology

A. Llebaria, Maria Ricart-Ortega, Joan Font, 2019, Molecular and Cellular Endocrinology.

Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology

Kira E. Poskanzer, G. Perea, P. Gorostiza, 2019, Proceedings of the National Academy of Sciences.

Modulation of Metabotropic Glutamate Receptors by Orthosteric, Allosteric, and Light-Operated Ligands

J. Pin, F. Acher, P. Rondard, 2018 .

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

P. Gorostiza, J. Giraldo, J. Pin, 2017, European journal of medicinal chemistry.

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

P. Gorostiza, J. Giraldo, J. Pin, 2016, Current neuropharmacology.

A double effect molecular switch leads to a novel potent negative allosteric modulator of metabotropic glutamate receptor 5

P. Gorostiza, J. Giraldo, J. Pin, 2014 .

Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches

A. Díaz-Tahoces, P. Gorostiza, P. de la Villa, 2016, Nature Communications.

Adamantane substituted aminocyclitols as pharmacological chaperones for Gaucher disease

A. Llebaria, A. Trapero, Meritxell Egido-Gabás, 2013 .

Glucocerebrosidase inhibitors for the treatment of Gaucher disease.

A. Llebaria, A. Trapero, 2013, Future medicinal chemistry.

Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in Gaucher cells.

T. Butters, A. Llebaria, I. Alfonso, 2011, Journal of the American Chemical Society.

Chemical Tools to Investigate Sphingolipid Metabolism and Functions

A. Llebaria, J. Casas, G. Fabriàs, 2007, ChemMedChem.

Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating gaucher disease.

T. Butters, Patricia González‐Bulnes, A. Llebaria, 2012, Journal of medicinal chemistry.

Aminocyclitols as Pharmacological Chaperones for Glucocerebrosidase, a Defective Enzyme in Gaucher Disease

A. Llebaria, D. Canals, J. Casas, 2007, ChemMedChem.

Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides.

C. Bedia, A. Llebaria, D. Canals, 2008, Chemistry and physics of lipids.

Environmental levels of carbaryl impair zebrafish larvae behaviour: The potential role of ADRA2B and HTR2B.

J. Mestres, M. Faria, C. Barata, 2022, Journal of hazardous materials.

This information is current as-Galactosylceramide C-α NKT TCR Recognition of CD 1 d-Godfrey and

T. Beddoe, J. McCluskey, D. Pellicci, 2011 .

NKT TCR Recognition of CD1d-α-C-Galactosylceramide

T. Beddoe, J. McCluskey, J. Rossjohn, 2011, The Journal of Immunology.

Specificity of the Dihydroceramide Desaturase Inhibitor N-[(1R,2S)-2-Hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in Primary Cultured Cerebellar Neurons

Amadeu Llebaria, G. van Echten-Deckert, A. Llebaria, 2004, Molecular Pharmacology.

Inhibitors of sphingolipid metabolism enzymes.

A. Llebaria, J. Casas, G. Fabriàs, 2006, Biochimica et biophysica acta.

Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities.

C. Bedia, A. Llebaria, J. Casas, 2005, Organic & biomolecular chemistry.

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase.

A. Llebaria, J. Casas, G. Fabriàs, 2003, The Journal of organic chemistry.

Synthesis of a Cyclopropene Analogue of Ceramide, a Potent Inhibitor of Dihydroceramide Desaturase This work was supported by the Dirección General de Enseñanza Superior e Investigación Científica (grant PB97-1171) and the Departament d'Universitats, Recerca i Societat de la Informació, Generalitat

A. Llebaria, G. Fabriàs, Gemma Triola, 2001, Angewandte Chemie.

A photoswitchable ligand targeting β1-adrenoceptor enables light-control of the cardiac rhythm

M. Faria, K. L. Martinez, X. Rovira, 2022, bioRxiv.

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

J. Pin, R. Marcellin, G. Lebon, 2018, Scientific Reports.

Glucocerebrosidase inhibitors: future drugs for the treatment of Gaucher disease?

A. Llebaria, A. Trapero, 2014, Future medicinal chemistry.

The myo-1,2-Diaminocyclitol Scaffold Defines Potent Glucocerebrosidase Activators and Promising Pharmacological Chaperones for Gaucher Disease.

A. Llebaria, A. Trapero, 2011, ACS medicinal chemistry letters.

Synthesis and evaluation of diverse analogs of amygdalin as potential peptidomimetics of peptide T.

Alex Rodriguez, A. Spada, J. Pérez, 2005, Bioorganic & medicinal chemistry letters.

THE YEAST MULTIFUNCTIONAL PROTEIN HAL3: STILL A SOURCE OF SURPRISES

D. Zajonc, P. Lauzurica, O. Akbari, 2012 .

S-Methyl-L-Ergothioneine to L-Ergothioneine Ratio in Urine Is a Marker of Cystine Lithiasis in a Cystinuria Mouse Model

Y. Kato, Virginia Nunes, A. Llebaria, 2021, Antioxidants.

Integrated Synthetic, Pharmacological, and Computational Investigation of cis‐2‐(3,5‐Dichlorophenylcarbamoyl)cyclohexanecarboxylic Acid Enantiomers As Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 4

Tatyana G. Karabencheva, C. Christov, J. Giraldo, 2011, ChemMedChem.

Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues.

O. Rabal, J. Teixidó, C. Bedia, 2006, Chemistry and physics of lipids.

Galacto configured N-aminoaziridines: a new type of irreversible inhibitor of β-galactosidases.

A. Llebaria, A. Trapero, Anna Alcaide, 2015, Organic & biomolecular chemistry.

Synthesis and biological properties of Pachastrissamine (jaspine B) and diastereoisomeric jaspines.

A. Llebaria, D. Canals, J. Casas, 2009, Bioorganic & medicinal chemistry.

Aziridine ring opening for the synthesis of sphingolipid analogues: inhibitors of sphingolipid-metabolizing enzymes.

A. Llebaria, Anna Alcaide, 2014, The Journal of organic chemistry.

Photoswitchable allosteric modulators for metabotropic glutamate receptors.

X. Rovira, A. Llebaria, X. Gómez-Santacana, 2022, Current opinion in pharmacology.

Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells.

O. Rabal, J. Teixidó, S. Grijalvo, 2007, Bioorganic & medicinal chemistry.

Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.

R. de la Torre, M. Farré, J. Segura, 2002, Journal of analytical toxicology.

Photoswitchable antagonists for a precise spatiotemporal control of β2-adrenoceptors.

X. Rovira, A. Llebaria, M. Otero-Viñas, 2020, Journal of medicinal chemistry.

Synthesis and preliminary antifungal evaluation of a library of phytosphingolipid analogues.

A. Llebaria, J. Casas, A. Delgado, 2007, Organic & biomolecular chemistry.

An efficient synthesis of 3,4-dioxocyclobutenecarboxylate derivatives

S. Ricart, A. Llebaria, F. Camps, 1990 .

Straightforward Access to Simplified Sphingosine‐1‐phosphate Analogues

S. Grijalvo, A. Llebaria, A. Delgado, 2007 .

Development and validation of a mass spectrometry binding assay for mGlu5 receptor

Alice E. Berizzi, C. Goudet, G. Lebon, 2020, Analytical and Bioanalytical Chemistry.

Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties

D. Zajonc, P. Lauzurica, O. Akbari, 2012, The Journal of Immunology.

Galacto-configured aminocyclitol phytoceramides are potent in vivo invariant natural killer T cell stimulators.

C. Barra, A. Llebaria, A. Delgado, 2011, Journal of the American Chemical Society.

Aminocyclitol‐Substituted Phytoceramides and their Effects on iNKT Cell Stimulation

C. Bedia, C. Barra, A. Llebaria, 2009, ChemMedChem.

Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells Published, JLR Papers in Press, December 2, 2005.

J. Balsinde, M. Balboa, A. Llebaria, 2006, Journal of Lipid Research.

Optical Modulation of Metabotropic Glutamate Receptor Type 5 In Vivo Using a Photoactive Drug.

F. Ciruela, A. Llebaria, Joan Font, 2019, Methods in molecular biology.

Formalin Murine Model of Pain.

F. Ciruela, A. Llebaria, V. Fernández-Dueñas, 2017, Bio-protocol.

Control of Theta Oscillatory Activity Underlying Fear Expression by mGlu5 Receptors

F. Ferraguti, A. Llebaria, X. Gómez-Santacana, 2022, Cells.

Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors

R. Jockers, H. Piggins, A. Llebaria, 2022, bioRxiv.

Caged-carvedilol as a new tool for visible-light photopharmacology of β-adrenoceptors in native tissues

M. Faria, X. Rovira, A. Rodríguez-Sinovas, 2022, iScience.

Identification of differential polypharmacology between the PARP inhibitor rucaparib and its major metabolite

A. Antolin, A. Llebaria, Huabin Hu, 2022, bioRxiv.

A prospect for pyrrolidine iminosugars as antidiabetic α-glucosidase inhibitors.

A. Llebaria, A. Trapero, 2012, Journal of medicinal chemistry.

3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans.

R. de la Torre, M. Farré, J. Segura, 2001, Chemical research in toxicology.

New aminocyclitols as modulators of glucosylceramide metabolism.

A. Llebaria, J. Casas, A. Delgado, 2005, Organic & biomolecular chemistry.

A two step procedure as improved alternative to the cyclocarbonylation of allyl halides and acetylene derivatives mediated by Ni(CO)4

A. Llebaria, J. Coll, F. Camps, 1988 .

Synthesis and evaluation of hydroxymethylaminocyclitols as glycosidase inhibitors.

A. Llebaria, A. Trapero, J. Bujons, 2015, The Journal of organic chemistry.

Studies on the competitive nickel-promoted carbonylative intramolecular cyclization of vinyl and aryl halides with hydroxyalkenes

A. Llebaria, A. Delgado, F. Camps, 1993 .

Stereoselective synthesis of tetrahydrofurans and tetrahydropyrans by Ni(0) promoted tandem cyclization-carbonylation

A. Llebaria, A. Delgado, F. Camps, 1994 .

Ni-promoted Cyclopentenone Formation by Intramolecular Cyclocarbonylation of 1-Bromo-1,4-dienes

A. Llebaria, F. Camps, J. Moretó, 1993 .

Synthesis of 1-thio-phytosphingolipid analogs by microwave promoted reactions of thiols and aziridine derivatives

A. Llebaria, Anna Alcaide, 2012 .

Asymmetric approaches to cyclopentenones in the Ni(0)-promoted cyclocarbonylation reaction of allyl halides and acetylenes

E. Molins, A. Llebaria, A. Delgado, 1996 .

Ring-fused and spiro cyclopentenones by Ni(CO)4-promoted intermolecular carbonylative cycloaddition of acetylenes with 3-halo- and 1-(halomethyl)cycloalkenes

E. Molins, A. Llebaria, F. Camps, 1992 .

Regio- and stereoselective synthesis of aminoinositols and 1,2-diaminoinositols from conduritol B epoxide.

A. Llebaria, A. Delgado, P. Serrano, 2005, The Journal of organic chemistry.

Diastereocontrolled synthesis of pyrrolidines by nickel promoted tandem cyclization-quenching of aminobromodienes

A. Llebaria, A. Delgado, J. Moretó, 1998 .

Intramolecular Nitrogen Assistance in the Nickel-Promoted Tandem Cyclization-Capture of Amino-Tethered Vinyl Bromides and Alkenes

A. Llebaria, A. Delgado, D. Solé, 1994 .

Versatile synthesis of bicyclo[4.3.0]nonenes and bicyclo[4.4.0]decenes by a domino Heck-Diels-Alder reaction

S. Bräse, A. Meijere, A. Llebaria, 1996 .

A practical synthesis of carbamates using an ‘in-situ’ generated polymer-supported chloroformate

A. Llebaria, A. Delgado, D. Mormeneo, 2004 .

Fused bicyclic systems through a ni-mediated intermolecular cyclopentenone annulation

A. Llebaria, F. Camps, L. Pagès, 1992 .

Nitrogen Assistance in Intramolecular Nickel-Promoted Tandem Cyclization−Quenching Processes

A. Llebaria, A. Delgado, D. Solé, 1996 .

Studies on the diastereoselective allylation of aldehydes with enantiopure 2-sulfinylallyl building blocks

A. Llebaria, A. Delgado, F. Márquez, 2001 .

An approach to homochiral fused and spiro cyclopentenones

A. Llebaria, A. Delgado, J. Moretó, 1995 .

Synthesis and phospholipase C inhibitory activity of D609 diastereomers

A. Llebaria, J. Casas, Albert González-Roura, 2002, Lipids.

Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses

Anthony Maxwell, Amadeu Llebaria, Amit Gandhi, 2018, Cell.

Barbier-type diastereoselective allylation of alpha-amino aldehydes with an enantiopure 2-sulfinylallyl building block.

E. Molins, A. Llebaria, A. Delgado, 2002, The Journal of organic chemistry.

Synthesis and capillary electrophoretic analysis of enantiomerically enriched reference standards of MDMA and its main metabolites.

R. de la Torre, M. Farré, J. Segura, 2002, Bioorganic & medicinal chemistry.

New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening.

A. Llebaria, J. Casas, J. Bujons, 2011, Journal of medicinal chemistry.

Practical synthesis of (-)-1-amino-1-deoxy-myo-inositol from achiral precursors.

Patricia González‐Bulnes, A. Llebaria, J. Casas, 2007, Carbohydrate research.

An unexpected chelation-controlled Yb(OTf)(3)-catalyzed aminolysis and azidolysis of cyclitol epoxides.

A. Llebaria, A. Delgado, P. Serrano, 2002, The Journal of organic chemistry.

An unexpected access to 5-epi-cyclophellitol: a new cyclitol member

Antonio Delgado, A. Llebaria, Meritxell Egido-Gabás, 2007 .

Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy

A. Llebaria, Laia Josa-Culleré, 2023, Journal of medicinal chemistry.

A solid-phase version of the palladium-catalyzed carbonyl allylation by allylic alcohols with SnCl2

A. Llebaria, A. Delgado, Lydia Carde, 2001 .

Versatile Synthesis of Bicyclo(4.3.0)nonenes and Bicyclo(4.4.0)decenes by a Domino Heck-Diels-Alder Reaction.

A. Meijere, A. Llebaria, F. Meyer, 1996 .

Preference for β-H elimination in the termination of the Ni-promoted carbonylative cycloaddition of 2-haloethylidene-cycloalkanes and alkynes

A. Llebaria, Alejandro Delgado, L. Pagès, 1998 .

The [Ni(CO)4]-promoted carbonylative cycloaddition of alkynes and allyl halides for the synthesis of 2-cyclopentenone derivatives

A. Llebaria, J. Moretó, 1993 .

New practical synthesis of spirocyclopentenones

A. Llebaria, F. Camps, L. Pagès, 1992 .

A solid-phase version of the Nozaki–Hiyama allylation of aldehydes with supported allylic bromides

A. Llebaria, A. Delgado, K. Breitenstein, 2004 .

Conjugate additions to alkynylalkoxycarbenemetal (Cr or W) complexes

S. Ricart, A. Llebaria, J. Ros, 1992 .

Conjugate addition of alcohols to alkynylalkoxycarbene metal (Cr, W) complexes

S. Ricart, A. Llebaria, J. Ros, 1991 .

2-aminohydroxamic acid derivatives as inhibitors of Bacillus cereus phosphatidylcholine preferred phospholipase C PC-PLC(Bc).

Patricia González‐Bulnes, A. Llebaria, D. Canals, 2010, Bioorganic & medicinal chemistry.

High-performance liquid chromatography with electrochemical detection applied to the analysis of 3,4-dihydroxymethamphetamine in human plasma and urine.

R. de la Torre, M. Farré, J. Segura, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase.

A. Llebaria, A. Trapero, Meritxell Egido-Gabás, 2011, Organic & biomolecular chemistry.

Formal Protection of Vinylepoxides via Stereospecific Chlorohydrin Formation

A. Llebaria, A. Delgado, Noemí Daviu, 1999 .

Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease.

A. Llebaria, J. Casas, J. Bujons, 2010, Journal of medicinal chemistry.

Molecular Basis for β‐Glucosidase Inhibition by Ring‐Modified Calystegine Analogues

G. Davies, C. Ortiz Mellet, J. G. García Fernández, 2008, Chembiochem : a European journal of chemical biology.

Diastereoselective Route to Piperidine and Indolizidine Scaffolds From Enantiopure Vinylsulfinyl-Containing Amino Alcohols

A. Llebaria, A. Delgado, R. Montoro, 2003 .

Synthesis and Biological Activity of a Novel Inhibitor of Dihydroceramide Desaturase

Antonio Delgado, Carmen Bedia, Amadeu Llebaria, 2008, ChemMedChem.

A Straightforward Protocol for the Solution‐Phase Parallel Synthesis of Ceramide Analogues

S. Grijalvo, A. Llebaria, A. Delgado, 2008 .

On the regio- and stereoselective synthesis of aminocyclitols from cyclitol epoxides: the effect of Li as a chelating agent.

J. de Pablo, J. Anglada, A. Llebaria, 2005, Chemistry.

A Straightforward Protocol for the Solution‐Phase Parallel Synthesis of Ceramide Analogues.

S. Grijalvo, A. Llebaria, A. Delgado, 2008 .

Aziridine Ring Opening for the Synthesis of Sphingolipid Analogues: Inhibitors of Sphingolipid‐Metabolizing Enzymes.

A. Llebaria, Anna Alcaide, 2014 .

A Practical Access to 1,2-Diaminophytosphingolipids.

A. Llebaria, A. Delgado, Y. Harrak, 2009 .

Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones.

R. Eritja, F. Albericio, A. Aviñó, 2008, Bioorganic & medicinal chemistry letters.

Iodocyclization of O-(3-Cyclohexenyl)thiocarbamidates. An Unexpected Approach to Vicinal cis-Aminocyclohexenols.

E. Molins, A. Llebaria, A. Delgado, 2000 .

Combinatorial approach to N-substituted aminocyclitol libraries by solution-phase parallel synthesis and preliminary evaluation as glucocerebrosidase inhibitors.

A. Llebaria, J. Casas, A. Delgado, 2007, Journal of combinatorial chemistry.

Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity

J. Lozano-Sánchez, A. Segura‐Carretero, S. Verdura, 2020, Aging.

OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity.

P. Gorostiza, J. Giraldo, J. Pin, 2016, Cell chemical biology.

Nickel-promoted intramolecular cyclization of vinyl bromides with alkenes and alkynes

A. Llebaria, F. Camps, J. Moretó, 1992 .

A catalytic version of a nickel promoted intramolecular tandem cyclization-cyanation process

A. Llebaria, A. Delgado, Susana Hinojosa, 1999 .

A Two Step Procedure as Improved Alternative to the Cyclocarbonylation of Allyl Halides and Acetylene Derivatives Mediated by Ni(CO)4.

A. Llebaria, J. Coll, F. Camps, 1989 .

C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.

D. Haro, A. Llebaria, P. Marrero, 2004, Biochemical and biophysical research communications.

Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites by gas chromatography/mass spectrometry.

R. de la Torre, M. Farré, J. Segura, 2003, Rapid communications in mass spectrometry : RCM.

In the Search for Photocages Cleavable with Visible Light: An Overview of Recent Advances and Chemical Strategies

A. Llebaria, Laia Josa-Culleré, 2020, ChemPhotoChem.

Fungal growth inhibitory properties of new phytosphingolipid analogues

A. Llebaria, Á. Manresa, D. Mormeneo, 2008, Journal of applied microbiology.

Remote local photoactivation of morphine produces analgesia without opioid‐related adverse effects

F. Ciruela, Y. de Koninck, J. Hernando, 2021, British journal of pharmacology.

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4

E. Valjent, J. Giraldo, F. Ferraguti, 2018, Molecular Psychiatry.

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

Alice E. Berizzi, J. Pin, F. Hoh, 2021, Cell reports.

A Novel Family of Lysosomotropic Tetracyclic Compounds for Treating Leukemia

R. Risueño, A. Llebaria, J. M. Carbó, 2023, Cancers.

Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology

C. Goudet, X. Rovira, A. Llebaria, 2018, Current opinion in pharmacology.

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

H. Daniel, X. Rovira, A. Llebaria, 2018, Front. Cell. Neurosci..

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

J. Pin, G. Lebon, J. Banères, 2018, Scientific Reports.

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer

J. Giraldo, J. Pin, P. Rondard, 2017, eLife.

Computational Analysis of Negative and Positive Allosteric Modulator Binding and Function in Metabotropic Glutamate Receptor 5 (In)Activation

Jesús Giraldo, James A. R. Dalton, Xavier Gómez-Santacana, 2014, J. Chem. Inf. Model..

A Practical Access to 1,2‐Diaminophytosphingolipids

A. Llebaria, A. Delgado, Y. Harrak, 2008 .

The antioxidant l-Ergothioneine prevents cystine lithiasis in the Slc7a9−/− mouse model of cystinuria

F. Pallardó, R. Artuch, P. García-Rovés, 2023, Redox biology.

PG12, a Phospholipid Analog with Potent Antimalarial Activity, Inhibits Plasmodium falciparum CTP:Phosphocholine Cytidylyltransferase Activity*

Choukri Ben Mamoun, H. Vial, Patricia González‐Bulnes, 2011, The Journal of Biological Chemistry.

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

F. Ciruela, P. Gorostiza, J. Giraldo, 2016, ACS central science.

Exploring the Active Conformation of Cyclohexane Carboxylate Positive Allosteric Modulators of the Type 4 Metabotropic Glutamate Receptor

J. Giraldo, J. Pin, C. Goudet, 2014, ChemMedChem.

Total synthesis of C37 alken-2-one temperature geomarkers

A. Llebaria, Lourdes Muñoz, Anna Alcaide, 2023, Tetrahedron Letters.

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

F. Ciruela, J. Giraldo, F. Nicoletti, 2017, eLife.

Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea

P. Gorostiza, T. Moser, A. Huet, 2021, bioRxiv.

Author response: Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer

J. Giraldo, J. Pin, P. Rondard, 2017 .

Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain.

C. Goudet, A. Llebaria, Vanessa Pereira, 2022, Pharmacological research.

Differential reduction of neuropathic pain symptoms by mGlu4-mediated neuromodulation of amygdala circuits

C. Goudet, A. Llebaria, Vanessa Pereira, 2022, bioRxiv.

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

F. Ciruela, P. Gorostiza, J. Giraldo, 2016, ACS Central Science.

Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides.

C. Bedia, A. Llebaria, J. Casas, 2008, Chemistry and physics of lipids.

Synthesis and Biological Activity of a Novel Inhibitor of Dihydroceramide Desaturase

C. Bedia, Antonio Delgado, A. Llebaria, 2008, ChemMedChem.

Optical Control of Adenosine A2A Receptor Using Istradefylline Photosensitivity.

C. Goudet, F. Malhaire, A. Llebaria, 2024, ACS chemical neuroscience.

Nucleophile-dependent stereodivergence in the Pd-catalyzed intramolecular cyclization of 2-(p-tolylsulfinyl)allylacetates

A. Roig, E. Molins, A. Llebaria, 1999 .