A. Jacobsson

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ELOVL3 Is an Important Component for Early Onset of Lipid Recruitment in Brown Adipose Tissue*

Petr Tvrdik, Kjetil Retterstøl, Anders Jacobsson, 2006, Journal of Biological Chemistry.

Differential regulation of fatty acid elongation enzymes in brown adipocytes implies a unique role for Elovl3 during increased fatty acid oxidation.

A. Jacobsson, A. Jakobsson, J. Jörgensen, 2005, American journal of physiology. Endocrinology and metabolism.

Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.

A. Jacobsson, P. Antonson, K. Xanthopoulos, 1995, European journal of biochemistry.

Impairment of DHA synthesis alters the expression of neuronal plasticity markers and the brain inflammatory status in mice

B. Ulfhake, T. Hessa, J. Napier, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Bioenergetics of Brown Fat Mitochondria from UCP1-ablated Mice

B. Cannon, J. Nedergaard, A. Jacobsson, 1999, The Journal of Biological Chemistry.

Norepinephrine and rosiglitazone synergistically induce Elovl3 expression in brown adipocytes.

D. Zadravec, A. Jacobsson, J. Jörgensen, 2007, American journal of physiology. Endocrinology and metabolism.

PPARγ in the control of brown adipocyte differentiation

N. Petrovic, B. Cannon, J. Nedergaard, 2005 .

Native UCP1 Displays Simple Competitive Kinetics between the Regulators Purine Nucleotides and Fatty Acids*

B. Cannon, J. Nedergaard, I. Shabalina, 2004, Journal of Biological Chemistry.

UCP1: The Original Uncoupling Protein—and Perhaps the Only One? New Perspectives on UCP1, UCP2, and UCP3 in the Light of the Bioenergetics of the UCP1-Ablated Mice

B. Cannon, J. Nedergaard, V. Golozoubova, 1999, Journal of bioenergetics and biomembranes.

Postnatal recruitment of brown adipose tissue is induced by the cold stress experienced by the pups. An analysis of mRNA levels for thermogenin and lipoprotein lipase.

T. Kirchgessner, M. Obregon, M. Schotz, 1989, The Biochemical journal.

The uncoupling protein thermogenin during acclimation: indications for pretranslational control.

B. Cannon, J. Nedergaard, A. Jacobsson, 1994, The American journal of physiology.

Life without UCP1: mitochondrial, cellular and organismal characteristics of the UCP1-ablated mice.

B. Cannon, J. Nedergaard, V. Golozoubova, 2001, Biochemical Society transactions.

Physiological activation of brown adipose tissue destabilizes thermogenin mRNA

B. Cannon, J. Nedergaard, A. Jacobsson, 1987, FEBS letters.

Norepinephrine utilizes alpha 1- and beta-adrenoreceptors synergistically to maximally induce c-fos expression in brown adipocytes.

P. Tvrdik, J. Nedergaard, H. Thonberg, 1994, The Journal of biological chemistry.

Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression.

M. Glotzer, L. Kozak, A. Jacobsson, 1985, The Journal of biological chemistry.

Differential adrenergic regulation of C/EBPα and C/EBPβ in brown adipose tissue

A. Jacobsson, P. Antonson, S. Rehnmark, 1993 .

Brown adipocytes differentiated in vitro can express the gene for the uncoupling protein thermogenin: effects of hypothyroidism and norepinephrine.

J. Kopecký, M. Obregon, B. Cannon, 1989, Experimental cell research.

Norepinephrine as a morphogen?: its unique interaction with brown adipose tissue.

B. Cannon, J. Nedergaard, A. Jacobsson, 1995, The International journal of developmental biology.

Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses

L. Battistini, C. Serhan, M. Maccarrone, 2016, Science Translational Medicine.

Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERα in Breast Cancer Cells

K. Dahlman-Wright, Hui Gao, A. Jacobsson, 2016, PloS one.

Impairment of systemic DHA synthesis affects macrophage plasticity and polarization: implications for DHA supplementation during inflammation

E. Talamonti, A. Jacobsson, Alexander W. Fischer, 2017, Cellular and Molecular Life Sciences.

Elovl2 ablation demonstrates that systemic DHA is endogenously produced and is essential for lipid homeostasis in mice[S]

D. Zadravec, A. Jacobsson, Robert I. Csikasz, 2014, Journal of Lipid Research.

Noradrenaline represses PPAR (peroxisome-proliferator-activated receptor) γ2 gene expression in brown adipocytes: intracellular signalling and effects on PPARγ2 and PPARγ1 protein levels

S. Mandrup, R. Nielsen, N. Petrovic, 2004 .

Cig30 and Pitx3 Genes Are Arranged in a Partially Overlapping Tail-to-Tail Array Resulting in Complementary Transcripts*

P. Tvrdik, L. Kozak, J. Nedergaard, 1999, The Journal of Biological Chemistry.

Steroid hormones control circadian Elovl3 expression in mouse liver.

A. Jacobsson, A. Pujol, A. Jakobsson, 2008, Endocrinology.

ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3-L1 and F442A cells.

D. Zadravec, Tsutomu Kobayashi, A. Jacobsson, 2008, FEBS letters.

ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3‐L1 and F442A cells

D. Zadravec, Tsutomu Kobayashi, A. Jacobsson, 2007 .

Contrasting adrenergic effects on lipoprotein lipase gene expression in the brown adipose tissue of intact mice and in cultured brown adipocytes from mice.

G. Heldmaier, M. Klingenspor, B. Cannon, 1997, Biochimica et biophysica acta.

ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

M. Capecchi, H. Guillou, J. Napier, 2011, Journal of Lipid Research.

mice by homologous recombination Abstract ELOVL2 is a member of the mammalian mi- crosomal ELOVL fatty acid enzyme family, involved in the elongation of very long-chain fatty acids including PUFAs

M. Capecchi, H. Guillou, J. Napier, 2011 .

PPARgamma in the control of brown adipocyte differentiation.

N. Petrovic, B. Cannon, J. Nedergaard, 2005, Biochimica et biophysica acta.

Signal transduction in brown adipose tissue recruitment: noradrenaline and beyond.

B. Cannon, J. Nedergaard, A. Jacobsson, 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

The Role of Adrenergic Stimulation in Regulation of Heat Production and Recruitment of Brown Adipose Tissue

P. Tvrdik, T. Bengtsson, B. Cannon, 1994 .

The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice.

Pascal G. P. Martin, H. Guillou, D. Zadravec, 2010, Progress in lipid research.

Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice[S]

Olga Dethlefsen, E. Talamonti, A. Jacobsson, 2016, Journal of Lipid Research.

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

T. Lindahl, P. Robins, B. Demple, 1982, The Journal of biological chemistry.

Role of a New Mammalian Gene Family in the Biosynthesis of Very Long Chain Fatty Acids and Sphingolipids

P. Tvrdik, S. Silve, B. Cannon, 2000, The Journal of cell biology.

Cig30, a Mouse Member of a Novel Membrane Protein Gene Family, Is Involved in the Recruitment of Brown Adipose Tissue*

P. Tvrdik, L. Kozak, B. Cannon, 1997, The Journal of Biological Chemistry.

Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria

R. Pamplona, A. Naudí, E. Talamonti, 2021, Nutrients.

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

B. Cannon, J. Nedergaard, V. Golozoubova, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Hitoshi Yamashita, Elizabeth M. Simpson, Mary-Ellen Harper, 1997, nature.

Fatty acid elongases in mammals: their regulation and roles in metabolism.

R. Westerberg, A. Jacobsson, A. Jakobsson, 2006, Progress in lipid research.

Thermogenic Responses in Brown Fat Cells Are Fully UCP1-dependent

B. Cannon, J. Nedergaard, A. Jacobsson, 2000, The Journal of Biological Chemistry.

Elovl1 and p55Cdc Genes Are Localized in a Tail-to-Tail Array and Are Co-expressed in Proliferating Cells*

A. Jacobsson, J. Jörgensen, A. Asadi, 2002, The Journal of Biological Chemistry.

Role for ELOVL3 and Fatty Acid Chain Length in Development of Hair and Skin Function*

M. Capecchi, P. Elias, P. Tvrdik, 2004, Journal of Biological Chemistry.

Ablation of the very‐long‐chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet‐induced obesity

J. Borén, H. Guillou, M. Rudling, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency.

A. Asadi, B. Cannon, J. Nedergaard, 2001, Biochimica et biophysica acta.

Uncoupling protein-1: involvement in a novel pathway for beta-adrenergic, cAMP-mediated intestinal relaxation.

T. Bengtsson, B. Cannon, J. Nedergaard, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Euthyroid status is essential for the perinatal increase in thermogenin mRNA in brown adipose tissue of rat pups.

M. Obregon, B. Cannon, J. Nedergaard, 1987, Biochemical and biophysical research communications.

Regulation of expression of the lipoprotein lipase gene in brown adipose tissue.

T. Kirchgessner, M. Schotz, B. Cannon, 1992, The American journal of physiology.

Impairment of Endogenous Synthesis of Omega-3 DHA Exacerbates T-Cell Inflammatory Responses

E. Talamonti, A. Jacobsson, V. Chiurchiù, 2023, International journal of molecular sciences.

α- andβ-adrenergic control of thermogenin mRNA expression in brown adipose tissue

B. Cannon, J. Nedergaard, A. Jacobsson, 1986 .

Is there a Life in the Cold without UCP1? Uncoupling Proteins Thermogenesis and Thermoregulatory

B. Cannon, V. Golozoubova, A. Jacobsson, 2000 .

Is there a Life in the Cold without UCP1? Uncoupling Proteins and Thermoregulatory Thermogenesis

B. Cannon, J. Nedergaard, V. Golozoubova, 2000 .

Cellular defense mechanisms against alkylation of DNA.

T. Lindahl, A. Jacobsson, B. Rydberg, 1982, Basic life sciences.

Evaluation of cost-precision rations of different strategies for ELISA measurement of serum antibody levels.

Joakim Dillner, Anders Jacobsson, Katarzyna Grabowska, 2002, Journal of immunological methods.

Synergistic Effects of DHA and Sucrose on Body Weight Gain in PUFA-Deficient Elovl2 -/- Mice

E. Talamonti, T. Bengtsson, A. Jacobsson, 2019, Nutrients.

Stabilization of the mRNA for the uncoupling protein thermogenin by transcriptional/translational blockade and by noradrenaline in brown adipocytes differentiated in culture: a degradation factor induced by cessation of stimulation?

C. Picó, A. Palou, B. Cannon, 1994, The Biochemical journal.

Adrenergic stimulation of lipoprotein lipase gene expression in rat brown adipocytes differentiated in culture: mediation via beta3- and alpha1-adrenergic receptors.

B. Cannon, J. Nedergaard, A. Jacobsson, 1997, Biochemical Journal.

Steroid hormones control circadian ELOVL3 expression in mouse liver

A. Jacobsson, A. Pujol, A. Jakobsson, 2008 .

Noradrenaline represses PPAR (peroxisome-proliferator-activated receptor) gamma2 gene expression in brown adipocytes: intracellular signalling and effects on PPARgamma2 and PPARgamma1 protein levels.

S. Mandrup, R. Nielsen, N. Petrovic, 2004, The Biochemical journal.

Uncoupling protein-1: involvement in a novel pathway for beta-adrenergic, cAMP-mediated intestinal relaxation.

T. Bengtsson, B. Cannon, J. Nedergaard, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Only UCP 1 can mediate adaptive nonshivering thermogenesis in the cold 1

B. Cannon, J. Nedergaard, V. Golozoubova, 2001 .

Epidermal 1-O-acylceramides appear with the establishment of the water permeability barrier in mice and are produced by maturating keratinocytes.

K. Willecke, J. Ntambi, J. Medin, 2022, Lipids.