J. Bend

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Relationship between biotransformation and the toxicity and fate of xenobiotic chemicals in fish.

J. Lech, J. Bend, 1980, Environmental health perspectives.

In vitro testing for the diagnosis of anticonvulsant hypersensitivity syndrome: a systematic review.

G. Koren, S. Knowles, M. Rieder, 2009, Molecular diagnosis & therapy.

The stereoselectivity of four hepatic glutathione S-transferases purified from a marine elasmobranch (Raja erinacea) with several K-region polycyclic arene oxide substrates.

J. Bend, G. Foureman, O. Hernandez, 1987, Biochimica et biophysica acta.

Metabolism and biliary excretion of benzo[a]pyrene 4,5-oxide in the rat.

J. Plummer, B. R. Smith, L. Ball, 1980, Drug metabolism and disposition: the biological fate of chemicals.

Regiospecificity and stereospecificity in the enzymatic conjugation of glutathione with (+/-)-benzo(a)pyrene 4,5-oxide.

B. R. Smith, R. Cox, J. Bend, 1980, Biochemical and Biophysical Research Communications - BBRC.

Synthesis and relative stereochemistry of the four mercapturic acids derived from styrene oxide and N-acetylcysteine.

B. Yagen, R. Cox, J. Bend, 1981, Chemico-biological interactions.

Chemical depletion of glutathione in vivo.

J. Plummer, B. R. Smith, H. Sies, 1981, Methods in enzymology.

In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung.

M. Boyd, T. Devereux, J. Bend, 1982, The Journal of pharmacology and experimental therapeutics.

The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol.

M. Boyd, C. Wolf, J. Bend, 1982, Molecular pharmacology.

Animals as monitors of environmental pollutants: North-East Center for Wildlife Diseases, Registry of Comparative Pathology, Armed Forces Institute of Pathology, Laboratory of Animal Resources, National Academy of Sciences, Washington, D.C., 1979, 421 pp.

J. Bend, 1981 .

Microsomal Mixed-Function Oxidation in Untreated and Polycyclic Aromatic Hydrocarbon-Treated Marine Fish

M. James, L. Ball, J. Bend, 1979 .

Urinary Pesticide Residual Levels and Acute Respiratory Infections in Children Under 5 Years of Age: Findings From the Offinso North Farm Health Study

I. Luginaah, R. Quansah, J. Bend, 2022, Environmental health insights.

Metabolism of benzo(a)pyrene and benzo(a)pyrene 4,5-oxide in rabbit lung.

J. Plummer, C. Wolf, T. Devereux, 1981, Advances in experimental medicine and biology.

Role of eicosanoids in the ischemic and reperfused myocardium.

M. Karmazyn, J. Bend, 1996, EXS.

The pulmonary uptake, accumulation, and metabolism of xenobiotics.

C. Serabjit-Singh, J. Bend, R. Philpot, 1985, Annual review of pharmacology and toxicology.

Red wine–cisapride interaction: Comparison with grapefruit juice

G. Dresser, D. Bailey, J. Bend, 2001, Clinical pharmacology and therapeutics.

Alteration of the Redox State of Nadph and Glutathione in Perfused Rabbit Lung By Paraquat

J. Horton, L. A. Dostal, J. Bend, 1986, Toxicology and industrial health.

Epoxide metabolizing enzyme activities in rat testes: postnatal development and relative activity in interstitial and spermatogenic cell compartments.

H. Mukhtar, J. Bend, G. Foureman, 1978, Chemico-biological interactions.

Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides

M. Rieder, J. Bend, A. Elzagallaai, 2019, Journal of clinical pharmacology.

Prediction of pulmonary benzo(a)pyrene 4,5-oxide clearance: a pharmacokinetic analysis of epoxide-metabolizing enzymes in rabbit lung.

B. R. Smith, J. Bend, 1980, The Journal of pharmacology and experimental therapeutics.

Cultural and socio-economic conditions as factors contributing to chronic stress in sub-Saharan African communities.

E. Russell, G. Koren, I. Creed, 2014, Canadian journal of physiology and pharmacology.

Severe bullous hypersensitivity reactions after exposure to carbamazepine in a Han-Chinese child with a positive HLA-B*1502 and negative in vitro toxicity assays: evidence for different pathophysiological mechanisms.

G. Koren, Y. Finkelstein, M. Rieder, 2011, Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique.

Estrogen receptor‐ and aryl hydrocarbon receptor‐mediated activities of a coal‐tar creosote

M. Fielden, T. Zacharewski, G. Hammond, 2000 .

Hair methylmercury: a new indication for therapeutic monitoring.

G. Koren, J. Bend, K. Schoeman, 2010, Therapeutic drug monitoring.

The effect of some biphenyl solubilizing and suspending agents on biphenyl 4-hydroxylase of rabbit liver microsomes.

G. Hook, J. Bend, J. Fouts, 1973, Chemico-biological interactions.

Benzo(a)pyrene metabolism in hepatic microsomes from feral and 3-methycholanthrene-treated southern flounder, Paralichthys lethostigma.

P. Little, M. James, J. Bend, 1984, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Stereoselectivity and regioselectivity of purified human glutathione transferases pi, alpha-epsilon, and mu with alkene and polycyclic arene oxide substrates.

B. Mannervik, L. A. Dostal, J. Bend, 1988, Drug metabolism and disposition: the biological fate of chemicals.

Mechanism controlling the renal excretion of xenobiotics in fish: effects of chemical structure.

J. Bend, J. B. Pritchard, John B. Pritchard, 1984, Drug metabolism reviews.

Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme.

B. Burchell, M. Coughtrie, J. Bend, 1987, Molecular pharmacology.

Variation of hepatic aryl hydrocarbon hydroxylase (AHH) and 7-ethoxyresorufin o-deethylase (7-ERD) activities in marine fish from Maine: Evidence that monooxygenase activities of only a few species are induced by environmental exposure to polycyclic aromatic hydrocarbon (PAH)-type compounds

J. Bend, Cary L. Foureman, 1984 .

Biochemical Evidence that Winter Flounder (Pseudopleuronectes americanus) have Induced Hepatic Cytochrome P-450-Dependent Monooxygenase Activities

N. B. White, J. Bend, G. Foureman, 1983 .

IN VITRO METABOLISM OF XENOBIOTICS IN SOME MARINE ANIMALS *

M. James, P. Dansette, J. Bend, 1977, Annals of the New York Academy of Sciences.

Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research.

J. Bend, 1980, Ciba Foundation symposium.

Heterogeneity of hepatic aryl hydrocarbon hydroxylase activity in feral winter flounder: relevance to carcinogenicity testing.

P. Albro, J. Bend, Z. Ben-Zvi, 1984, National Cancer Institute monograph.

Toxicity of Prudhoe Bay crude oil and its aromatic fractions to nestling herring gulls.

D. Peakall, D. Miller, D. Hallett, 1982, Environmental research.

Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine.

A. Guarino, J. Bend, J. Fouts, 1974, Drug metabolism and disposition: the biological fate of chemicals.

Taurine conjugation of 2,4-dichlorophenoxyacetic acid and phenylacetic acid in two marine species.

M. James, J. Bend, 1976, Xenobiotica; the fate of foreign compounds in biological systems.

Hepatic microsomal mixed-function oxidase activities in several marine species common to coastal Florida

M. James, J. Bend, M. A. Khan, 1979 .

Polycyclic aromatic hydrocarbon induction of cytochrome P-450-dependent mixed-function oxidases in marine fish.

M. James, J. Bend, M. O. James, 1980, Toxicology and applied pharmacology.

The role of glutathione S-transferases in the hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from polluted and reference sites in the Great Lakes.

J. Bend, M. A. Hayes, I. Smith, 1990, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

In vitro and in vivo metabolism of benzo(a)pyrene by selected marine crustacean species

P. Little, M. James, J. Bend, 1981 .

Temperature-dependent disposition of [14C]benzo(a)pyrene in the spiny lobster, Panulirus argus.

P. Little, M. James, J. Bend, 1985, Toxicology and applied pharmacology.

Cytosolic glutathione S-transferases in various rat tissues differ in stereoselectivity with polycyclic arene and alkene oxide substrates.

L. A. Dostal, C. Harris, A. Aitio, 1986, Drug metabolism and disposition: the biological fate of chemicals.

The hepatic glutathione transferases of the male little skate, Raja erinacea.

J. Bend, G. Foureman, 1984, Chemico-biological interactions.

Selective increase of rat lung cytochrome P450 1A1 dependent monooxygenase activity after acute sodium arsenite administration.

A. Albores, J. Bend, M. Cherian, 1995, Canadian journal of physiology and pharmacology.

Effects of acute sodium arsenite administration on the pulmonary chemical metabolizing enzymes, cytochrome P-450 monooxygenase, NAD(P)H:quinone acceptor oxidoreductase and glutathione S-transferase in guinea pig: comparison with effects in liver and kidney.

J. Bend, K. Falkner, M. Cherian, 1993, Chemico-biological interactions.

THE CAPABILITIES OF FISH AND OTHER AQUATIC ORGANISMS FOR XENOBIOTIC METABOLISM

J. Bend, G. Foureman, 1983 .

Thyroid hormone-induced changes in the hepatic monooxygenase system, heme oxygenase activity and epoxide hydrolase activity in adult male, female and immature rats.

H. Mukhtar, J. Bend, J. Fouts, 1982, Chemico-biological interactions.

Acute sodium arsenite treatment induces Cyp2a5 but not Cyp1a1 in the C57Bl/6 mouse in a tissue (kidney) selective manner

J. Seubert, J. Bend, C. D. Webb, 2002, Journal of biochemical and molecular toxicology.

Acute sodium arsenite administration induces pulmonary CYP1A1 mRNA, protein and activity in the rat

J. Seubert, J. Bend, C. Sinal, 2002, Journal of biochemical and molecular toxicology.

Biochemical effects of pure isomers of hexachlorobiphenyl -- hepatic microsomal epoxide hydrase and cytosolic glutathione S-transferase activities in the rat.

K. K. Kohli, P. Albro, H. Mukhtar, 1979, Biochemical pharmacology.

Partially Induced Hepatic Mixed-Function Oxidase Systems in Individual Members of Certain Marine Species from Coastal Maine and Florida

M. James, J. Bend, G. Foureman, 1978 .

Relative roles of metabolism and renal excretory mechanisms in xenobiotic elimination by fish.

J. Bend, J. B. Pritchard, John B. Pritchard, 1991, Environmental health perspectives.

Female-predominant expression of testosterone 16α-hydroxylase (“I”-P-45016α) and its repression in strain 129/J

M. Noshiro, M. Negishi, C. Serabjit-Singh, 1986 .

Hormonal regulation of cytochrome P-450-dependent monooxygenase activity and epoxide-metabolizing enzyme activities in testis of hypophysectomized rats.

H. Mukhtar, J. Bend, I. Lee, 1980, Cancer research.

Effects of vitamin A deficiency on hepatic and extrahepatic mixed-function oxidase and epoxide-metabolizing enzymes in guinea pig and rabbit.

H. Mukhtar, C. Miranda, J. Bend, 1979, Biochemical pharmacology.

Epoxide hydrase and mixed-function oxidase activities of rat liver nuclear membranes.

H. Mukhtar, J. Bend, T. H. Elmamlouk, 1979, Archives of biochemistry and biophysics.

Attenuation of t-Butylhydroperoxide induced oxidative stress in HEK 293 WT cells by tea catechins and anthocyanins

F. Wachira, J. Bend, Wanyoko, 2011 .

In Vitro Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome

G. Koren, S. Knowles, M. Rieder, 2009, Molecular Diagnosis & Therapy.

Epoxide hydrase and glutathione S-transferase activities with selected alkene and adrene oxides in several marine species.

M. James, P. Dansette, J. Bend, 1979, Chemico-biological interactions.

DDE-induced microsomal mixed-function oxidases in the puffin. (Fratercula arctica). (Fratercula arctica).

D. Peakall, D. Miller, J. Bend, 1977, Biochemical pharmacology.

A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit.

G. Hook, J. Bend, J. Fouts, 1972, The Journal of pharmacology and experimental therapeutics.

Chapter 11 – Metabolism of Epoxides

J. Bend, O. Hernandez, 1982 .

Concentration-dependent metabolism and toxicity of [14C] styrene oxide in the isolated perfused rat liver.

B. R. Smith, J. Bend, J. Fouts, 1979, The Journal of pharmacology and experimental therapeutics.

Estimation of the styrene 7,8-oxide-detoxifying potential of epoxide hydrolase in glutathione-depleted, perfused rat livers.

B. R. Smith, J. Bend, J. Fouts, 1983, The Journal of pharmacology and experimental therapeutics.

The metabolism and excretion of styrene oxide-glutathione conjugates in the rat and by isolated perfused liver, lung and kidney preparations.

B. R. Smith, B. Yagen, R. Cox, 1981, The Journal of pharmacology and experimental therapeutics.

METABOLISM OF BENZO(a)PYRENE IN LITTLE SKATE MIXED-FUNCTION OXIDASE SYSTEMS

L. Ball, J. Bend, T. H. Elmamlouk, 1980 .

Potential Complementary Therapy for Adverse Drug Reactions to Sulfonamides: Chemoprotection Against Oxidative and Nitrosative Stress by TCM Constituents and Defined Mixtures.

M. Rieder, J. Bend, Dao-feng Chen, 2015, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Pulmonary cytochrome P 450 2 J 4 ( CYP 2 J 4 ) is reduced in a rat model of acute Pseudomonas pneumonia

D. Zeldin, J. A. Bradbury, D. McCormack, 2003 .

Pulmonary cytochrome P-450 2J4 is reduced in a rat model of acute Pseudomonas pneumonia.

D. Zeldin, J. A. Bradbury, D. McCormack, 2003, American journal of physiology. Lung cellular and molecular physiology.

trans-Stilbene oxide: an inducer of rat hepatic microsomal and nuclear epoxide hydrase and mixed-function oxidase activities.

H. Mukhtar, J. Bend, T. H. Elmamlouk, 1978, Chemico-biological interactions.

Glutathione S-Transferases

D. Jerina, J. Bend, 1977 .

p-Xylene metabolism by rabbit lung and liver and its relationship to the selective destruction of pulmonary cytochrome P-450.

J. Plummer, C. Wolf, B. R. Smith, 1982, The Journal of pharmacology and experimental therapeutics.

Imidazole derivatives as inhibitors of cytochrome P-450-dependent oxidation and activators of epoxide hydrolase in hepatic microsomes from a marine fish.

P. Little, M. James, J. Bend, 1981, Biochemical pharmacology.

Synthesis and relative stereochemistry of the benzylic thioether diastereoisomers formed from glutathione and styrene oxide

B. Yagen, R. Cox, J. Bend, 1981 .

The metabolism and excretion of 14C-styrene oxide-glutathione adducts administered to the winter flounder, Pseudopleuronectes americanus, a marine teleost. Identification of the corresponding S-cysteine derivatives as major urinary metabolites.

B. Yagen, R. Cox, J. Bend, 1984, Drug metabolism and disposition: the biological fate of chemicals.

Fate and distribution of the herbicides 2,4-dichlor-phenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in the dogfish shark.

A. Guarino, M. James, J. Bend, 1977, Xenobiotica; the fate of foreign compounds in biological systems.

Hepatic and extrahepatic metabolism of 14C-styrene oxide

M. James, J. Bend, Z. Ben-Zvi, 1976, Environmental health perspectives.

Aryl hydrocarbon receptor-dependent induction of cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells.

J. Bend, C. Sinal, 1997, Molecular pharmacology.

Global changes in gene regulation demonstrate that unconjugated bilirubin is able to upregulate and activate select components of the endoplasmic reticulum stress response pathway

J. Bend, G. Oakes, 2010, Journal of biochemical and molecular toxicology.

Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia.

D. McCormack, J. Bend, J. Scott, 2001, The Journal of pharmacology and experimental therapeutics.

Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney

J. Bend, C. D. Webb, C. Sinal, 1999, Journal of biochemical and molecular toxicology.

Liver transplantation induces cytochrome P450 1A1 dependent monooxygenase activity in rat lung and kidney.

J. Bend, M. Cherian, R. Zhong, 1995, Canadian journal of physiology and pharmacology.

Effects of arsenite treatment on NAD(P)H:quinone acceptor oxidoreductase activity in liver, lung, kidney, and heart of the rat. Comparison to induction by the polyaromatic hydrocarbon, beta-naphthoflavone.

J. Bend, K. Falkner, G. McCallum, 1993, Drug metabolism and disposition: the biological fate of chemicals.

Attenuation of Oxidative Stress in HEK 293 Cells by the TCM Constituents Schisanhenol, Baicalein, Resveratrol or Crocetin and Two Defined Mixtures.

Serum glutathione S-transferases: perinatal development, sex difference, and effect of carbon tetrachloride administration on enzyme activity in the rat.

H. Mukhtar, J. Bend, 1977, Life sciences.

Hepatic and extrahepatic metabolism, in vitro, of an epoxide (8-(14) C-styrene oxide) in the rabbit.

M. James, J. Bend, J. Fouts, 1976, Biochemical pharmacology.

Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.

J. Halpert, G. Szklarz, A. Vaz, 1997, Biochemistry.

A radiochemical assay for glycine N-acyltransferase activity. Some properties of the enzyme in rat and rabbit.

M. James, J. Bend, 1978, The Biochemical journal.

Respiratory and non-respiratory symptoms associated with pesticide management practices among farmers in Ghana’s most important vegetable hub

S. Afful, I. Luginaah, S. Cobbina, 2019, Environmental Monitoring and Assessment.

Lung perfusion techniques for xenobiotic metabolism and toxicity studies.

B. R. Smith, J. Bend, 1981, Methods in enzymology.

Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes.

M. Karmazyn, T. Mock, J. Bend, 1993, The American journal of physiology.

Fish consumption in pregnancy and fetal risks of methylmercury toxicity.

G. Koren, J. Bend, 2010, Canadian family physician Medecin de famille canadien.

Hair mercury levels of women of reproductive age in Ontario, Canada: implications to fetal safety and fish consumption.

G. Koren, Toshihiro Tanaka, J. Bend, 2010, The Journal of pediatrics.

Pulmonary metabolism of xenobiotics.

G. Hook, J. Bend, 1976, Life sciences.

Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.

J. Bend, L. Knickle, 1994, Molecular pharmacology.

Analysis of glutathione conjugates and related compounds by thermospray mass spectrometry.

K. Tomer, J. Sanders, J. Bend, 1988, Biomedical & environmental mass spectrometry.

Dose-dependent, mechanism-based inactivation of cytochrome P450 monooxygenases in vivo by 1-aminobenzotriazole in liver, lung, and kidney of untreated, phenobarbital-treated, and beta-naphthoflavone-treated guinea pigs.

J. Bend, L. Knickle, 1992, Canadian journal of physiology and pharmacology.

Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.

L. A. Dostal, J. Bend, J. Mathews, 1985, The Journal of pharmacology and experimental therapeutics.

Purification and biochemical characterization of the rabbit pulmonary glutathione S-transferase: stereoselectivity and activity toward pyrene 4,5-oxide.

C. Serabjit-Singh, J. Bend, 1988, Archives of biochemistry and biophysics.

Tissue and cellular differences in the expression of cytochrome P-450 isozymes

T. Devereux, C. Serabjit-Singh, J. Bend, 1984 .

THE SOCIETY OF HAIR TESTING

G. Koren, R. Darnell, J. Bend, 2012 .

Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: Comparison with grapefruit juice

G. Dresser, D. Bailey, J. Bend, 2003, Clinical pharmacology and therapeutics.

Enantioselective, mechanism-based inactivation of guinea pig hepatic cytochrome P450 by N-(alpha-methylbenzyl)-1-aminobenzotriazole.

M. Hirst, J. Bend, C. D. Webb, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Reviews in biochemical toxicology

E. Hodgson, J. Bend, R. Philpot, 1979 .

Patch Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome

G. Koren, S. Knowles, M. Rieder, 2009, Drug safety.

Hepatic and Extrahepatic Mixed-Function Oxidases

G. Hook, J. Bend, 2011 .

Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver.

G. Hook, D. Hoel, J. Bend, 1972, The Journal of pharmacology and experimental therapeutics.

Quantitation of benzo(a)pyrene metabolite: DNA adducts in selected hepatic and pulmonary cell types isolated from [3H]benzo(a)pyrene-treated rabbits.

J. Horton, M. Anderson, J. Bend, 1985, Cancer research.

Glutathione S-transferase activities in rat and mouse sperm and human semen.

H. Mukhtar, J. Bend, I. Lee, 1978, Biochemical and biophysical research communications.

Mutagenicity of (R) and (S) styrene 7,8-oxide and the intermediary mercapturic acid metabolites formed from styrene 7,8-oxide.

E. Zeiger, D. Pagano, B. Yagen, 1982, Environmental mutagenesis.

Metabolism and excretion of benzo(a)pyrene 4,5-oxide by the isolated perfused rat liver.

B. R. Smith, J. Bend, 1979, Cancer research.

In Vitro Testing for Hypersensitivity‐Mediated Adverse Drug Reactions: Challenges and Future Directions

G. Koren, M. Rieder, J. Bend, 2011, Clinical pharmacology and therapeutics.

Cytochrome P-450 monooxygenase system. Localization in smooth muscle of rabbit aorta.

C. Serabjit-Singh, J. Bend, R. Philpot, 1985, Molecular pharmacology.

Mixed-function oxidases and the alveolar macrophage.

G. Hook, J. Bend, J. Fouts, 1972, Biochemical pharmacology.

The rabbit pulmonary monooxygenase system. Catalytic differences between two purified forms of cytochrome P-450 in the metabolism of benzo(a)pyrene.

C. Wolf, B. R. Smith, L. Ball, 1979, The Journal of biological chemistry.

Epoxide-metabolizing enzyme activities and cytochrome P-450 content of rat ovaries during pregnancy.

H. Mukhtar, J. Bend, R. Philpot, 1978, Biochemical and biophysical research communications.

Aryl Hydrocarbon Receptor-Dependent Induction of Cyp 1 a 1 by Bilirubin in Mouse Hepatoma Hepa 1 c 1 c 7 Cells

J. Bend, C. Sinal, 1997 .

Stereoselectivity of styrene oxidation in microsomes and in purified cytochrome P-450 enzymes from rat liver.

F. Guengerich, C. Harris, J. Bend, 1989, The Journal of pharmacology and experimental therapeutics.

Acyclovir-induced nephrotoxicity: the role of the acyclovir aldehyde metabolite.

G. Koren, J. Bend, K. Aleksa, 2011, Translational research : the journal of laboratory and clinical medicine.

Erythromycin‐felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice

D. Bailey, J. Bend, J. M. Arnold, 1996, Clinical pharmacology and therapeutics.

Targeted Disruption of Soluble Epoxide Hydrolase Reveals a Role in Blood Pressure Regulation*

F. Gonzalez, M. Tohkin, M. Miyata, 2000, The Journal of Biological Chemistry.

A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid.

B. Burchell, M. Coughtrie, J. Bend, 1986, Analytical biochemistry.

Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole.

Charles V. Smith, S. Welty, B. Moorthy, 2000, The Journal of pharmacology and experimental therapeutics.

Mechanisms Controlling Excretion of Xenobiotics of Chemical Structure* the Renal in Fish: Effects

J. Bend, J. B. Pritchard, 1984 .

Thiocyanate inhibition of ATPase and its relationship to anion transport.

F. Epstein, J. Bend, P. Silva, 1975, The American journal of physiology.

Associations between pesticide use and respiratory symptoms: A cross-sectional study in Southern Ghana.

S. Afful, I. Luginaah, S. Cobbina, 2016, Environmental research.

Relationships between exposure to polyhalogenated aromatic hydrocarbons and organochlorine pesticides and the risk for developing type 2 diabetes: a systematic review and a meta-analysis of exposures to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

G. Koren, J. Bend, M. Moretti, 2012 .

Development of Drugs from Plants

M. Rieder, J. Bend, 2012 .

Health Impact of Pesticides on Residents and Horticultural Workers in the Lake Naivasha Region, Kenya

Pamela F. Tsimbiri, Wilkister N. Moturi, Judith Sawe, 2015 .

The perinatal development of epoxide-metabolizing enzyme activities in liver and extrahepatic organs of guinea pig and rabbit.

M. James, J. Bend, G. Foureman, 1977, Drug metabolism and disposition: the biological fate of chemicals.

Selective inhibitors of cytochromes P450.

F. Guengerich, J. Halpert, M. Correia, 1994, Toxicology and applied pharmacology.

Characterization of lung microsomes as related to drug metabolism.

G. Hook, J. Bend, T. E. Gram, 1973, Drug Metabolism And Disposition.

Grapefruit‐felodipine interaction: Effect of unprocessed fruit and probable active ingredients

G. Dresser, D. Bailey, J. Bend, 2000, Clinical pharmacology and therapeutics.

Characteristics and development of drug metabolism by pulmonary microsomes

T. Devereux, M. James, J. Bend, 1976, Agents and Actions.

Excess nitric oxide decreases cytochrome P-450 2J4 content and P-450-dependent arachidonic acid metabolism in lungs of rats with acute pneumonia.

D. Zeldin, D. McCormack, J. Bend, 2004, American journal of physiology. Lung cellular and molecular physiology.

Characterization of pulmonary arene oxide biotransformation using the perfused rabbit lung.

J. Plummer, B. R. Smith, L. Ball, 1980, Cancer research.

Characterization of PulmonaryArene Oxide BiotransformationUsingthe Perfused Rabbit Lung1

B. Smith, J. Plummer, L. Ball, 1980 .

Metabolism of xenobiotics by the isolated perfused lung. Comparison with in vitro incubations.

T. Eling, J. Bend, J. Fouts, 1974, Drug metabolism and disposition: the biological fate of chemicals.

Metabolism of benzo[a]pyrene by the isolated perfused rabbit lung.

B. R. Smith, J. Bend, R. Philpot, 1978, Drug metabolism and disposition: the biological fate of chemicals.

Epoxide hydrase activity in liver nuclei: hydration of benzo[a]pyrene-4,5-oxide and styrene oxide.

H. Mukhtar, E. Bresnick, J. Bend, 1978, Chemico-biological interactions.

Deacetylation to 2-aminofluorene as a major initial reaction in the microsomal metabolism of 2-acetylaminofluorene to mutagenic products in preparations from rabbit lung and liver.

E. Dybing, T. Aune, J. Bend, 1985, Cancer research.

Xenobiotic metabolism in Clara cells and alveolar type II cells isolated from lungs of rats treated with beta-naphthoflavone.

J. Holland, J. Bend, G. Foureman, 1983, The Journal of pharmacology and experimental therapeutics.

Metabolism and toxicity of benzo(a)pyrene-4,5-oxide in the isolated perfused rat liver.

B. R. Smith, J. Bend, 1979, Toxicology and applied pharmacology.

HIV-1 tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells

M. Rieder, J. Bend, G. Dekaban, 2018, Virology Journal.

The postnatal development of microsomal expoxide hydrase, cytosolic glutathione S-transferase, and mitochondrial and microsomal cytochrome P-450 in adrenals and ovaries of female rats.

H. Mukhtar, J. Bend, R. Philpot, 1978, Drug metabolism and disposition: the biological fate of chemicals.

Paraquat uptake into freshly isolated rabbit lung epithelial cells and its reduction to the paraquat radical under anaerobic conditions.

J. Horton, R. Mason, J. Bend, 1986, Molecular pharmacology.

Evidence for a free radical mechanism of styrene-glutathione conjugate formation catalyzed by prostaglandin H synthase and horseradish peroxidase.

T. Eling, R. Mason, J. Bend, 1986, The Journal of biological chemistry.

Apoptosis in murine hepatoma hepa 1c1c7 wild-type, C12, and C4 cells mediated by bilirubin.

A. El-Kadi, J. Seubert, S. D'souza, 2002, Molecular pharmacology.

Apoptosis in Murine Hepatoma Hepa 1 c 1 c 7 Wild-Type , C 12 , and C 4 Cells Mediated by Bilirubin

A. El-Kadi, J. Seubert, S. D'souza, 2002 .

A Surveillance Method for the Early Identification of Idiosyncratic Adverse Drug Reactions

G. Koren, M. Rieder, J. Bend, 2008, Drug safety.

N-alkylaminobenzotriazoles as isozyme-selective suicide inhibitors of rabbit pulmonary microsomal cytochrome P-450.

J. Bend, J. Mathews, J. M. Mathews, 1986, Molecular pharmacology.

Rabbit pulmonary cytochrome P-450 monooxygenase system: isozyme differences in the rate and stereoselectivity of styrene oxidation.

C. Harris, J. Bend, R. Philpot, 1986, The Journal of pharmacology and experimental therapeutics.

Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.

T. Massey, L. Bedard, J. Bend, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Defining a Lowest Observable Adverse Effect Hair Concentrations of Mercury for Neurodevelopmental Effects of Prenatal Methylmercury Exposure Through Maternal Fish Consumption: A Systematic Review

G. Koren, J. Bend, K. Nash, 2009, Therapeutic drug monitoring.

Purification and properties of rat kidney UDP-glucuronosyltransferase.

B. Burchell, M. Coughtrie, J. Bend, 1987, Biochemical pharmacology.

Inhibition of rat liver glutathione S‐transferase activity by aprotic solvents

A. Aitio, J. Bend, 1979, FEBS letters.

Grapefruit juice—felodipine interaction: Effect of naringin and 6′,7′‐dihydroxybergamottin in humans

D. Bailey, J. Bend, D. Freeman, 1998, Clinical pharmacology and therapeutics.

The formation of styrene glutathione adducts catalyzed by prostaglandin H synthase. A possible new mechanism for the formation of glutathione conjugates.

T. Eling, J. Bend, B. Stock, 1986, Journal of Biological Chemistry.

Glutathione biosynthesis from sulfur-containing amino acids in enriched populations of Clara and type II cells and macrophages freshly isolated from rabbit lung.

J. Horton, J. Bend, M. Meredith, 1987, The Journal of pharmacology and experimental therapeutics.

Early steps in bilirubin‐mediated apoptosis in murine hepatoma (Hepa 1c1c7) cells are characterized by aryl hydrocarbon receptor‐independent oxidative stress and activation of the mitochondrial pathway

J. Bend, G. Oakes, 2005, Journal of biochemical and molecular toxicology.

Xenobiotic Metabolizing Enzymes in Marine Fish

M. James, J. Bend, J. Fouts, 1977 .

Inhalation studies with a glycol complex of aluminum-chloride-hydroxide.

B. N. Gupta, G. Hook, R. T. Drew, 1974, Archives of environmental health.

Microsomal cytochrome P450 peroxygenase metabolism of arachidonic acid in guinea pig liver.

J. Bend, G. McCallum, A. C. Weedon, 1996, The Journal of pharmacology and experimental therapeutics.

The nuclear envelope as a site of glucuronyltransferase in rat liver: properties of and effect of inducers on enzyme activity.

H. Mukhtar, J. Bend, T. H. Elmamlouk, 1981, The Journal of pharmacology and experimental therapeutics.

Metabolism and Excretion of Benzo(a)pyrene 4,5Oxide by the Isolated Perfused Rat Liver'

B. Smith, J. Bend, 2006 .

Hair Cortisol as a Biomarker of Stress Among a First Nation in Canada

G. Koren, S. Van Uum, J. Bend, 2013, Therapeutic drug monitoring.

Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation.

D. Bailey, J. Bend, Spence Jd, 1995, British journal of clinical pharmacology.

Benzpyrene hydroxylase activity in hepatic microsomal and solubilized systems containing rabbit or rat cytochrome P-448 or P-450.

J. Bend, R. Philpot, 1975, Life sciences.

Perinatal development of, and effect of chemical pretreatment on, glycine N-acyltransferase activities in liver and kidney of rabbit and rat.

M. James, J. Bend, 1978, The Biochemical journal.

Grapefruit juice—terfenadine single‐dose interaction: Magnitude, mechanism, and relevance

S. E. Rau, D. Bailey, J. Bend, 1997, Clinical pharmacology and therapeutics.

Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.

J. Bend, C. Sinal, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Role of lipoxygenase, cyclooxygenase and cytochrome P-450 metabolites in contractions of isolated guinea pig pulmonary venules induced by hypoxia and anoxia.

N. Paterson, J. Bend, W. R. Tracey, 1989, The Journal of pharmacology and experimental therapeutics.

Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.

K. Woodcroft, J. Bend, M. Yao, 1997, Chemical research in toxicology.

Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.

D. Gage, P. Hollenberg, B. Chamberlin, 1997, Chemical research in toxicology.

Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.

S. Grimm, J. Halpert, J. Bend, 1995, Drug metabolism and disposition: the biological fate of chemicals.

N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme-selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo.

J. Bend, J. Mathews, 1993, The Journal of pharmacology and experimental therapeutics.

Three N-aralkylated derivatives of 1-aminobenzotriazole as potent and isozyme-selective, mechanism-based inhibitors of guinea pig pulmonary cytochrome P-450 in vitro.

K. Woodcroft, J. Bend, L. Knickle, 1990, Drug metabolism and disposition: the biological fate of chemicals.

N-aralkylated derivatives of 1-aminobenzotriazole as isozyme-selective, mechanism-based inhibitors of guinea pig hepatic cytochrome P-450 dependent monooxygenase activity.

K. Woodcroft, J. Bend, 1990, Canadian journal of physiology and pharmacology.

Isozyme-selective metabolic intermediate complex formation of guinea pig hepatic cytochrome P450 by N-aralkylated derivatives of 1-aminobenzotriazole.

J. Bend, C. Sinal, 1995, Chemical research in toxicology.

HPLC Analysis of the Isomeric Thioether Metabolites of Styrene Oxide

B. Yagen, R. Cox, J. McKinney, 1982 .

Deacetylationto 2-Aminofluoreneas a Major InitialReactionin the Microsomal Metabolismof 2-Acetylaminofluoreneto MutagenicProductsin Preparationsfrom RabbitLungand Liver

E. Dybing, T. Aune, J. Bend, 1985 .

Global changes in gene regulation demonstrate that unconjugated bilirubin is able to upregulate and activate select components of the endoplasmic reticulum stress response pathway

J. Bend, G. Oakes, 2010, Journal of biochemical and molecular toxicology.

Patch Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome

G. Koren, S. Knowles, M. Rieder, 2009, Drug safety.

HEPATIC MICROSOMAL AND SOLUBILIZED MIXED-FUNCTION OXIDASE SYSTEMS FROM THE LITTLE SKATE, Raja erinacea, A MARINE ELASMOBRANCH

J. Bend, R. Philpot, E. Arınç, 1977 .

Precocious development of hepatic glutathione S-transferase activity with glucocorticoid administration in neonatal rat.

H. Mukhtar, J. Bend, J. Fouts, 1979, Biochemical pharmacology.

Metabolism of benzo[a]pyrene 4,5-oxide by isolated perfused rat testis.

H. Mukhtar, J. Bend, I. Lee, 1983, Biochemical pharmacology.

A Hybrid Classification Tree and Artificial Neural Network Model for Predicting the In vitro Response of the Human Immunodeficiency Virus (HIV1) to Anti-Viral Drug Therapy

D. Gregson, W. R. Danter, K. A Ferguson, 2000, ANNIMAB.

This material is the copyright of the original publisher. Unauthorised copying and distribution is prohibited. In Vitro Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome

G. Koren, S. Knowles, M. Rieder, 2009 .