C. Jackaman

发表

Macrophage function in the elderly and impact on injury repair and cancer

M. Grounds, L. Duong, HG Radley, 2021, Immunity & Ageing.

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

S. Dhaliwal, D. Nelson, C. Jackaman, 2015, Immunity & Ageing.

Targeting macrophages rescues age‐related immune deficiencies in C57BL/6J geriatric mice

M. Grounds, T. Shavlakadze, Z. Soffe, 2013, Aging cell.

CD40‐activated B cells contribute to mesothelioma tumor regression

S. Cornwall, D. Nelson, C. Jackaman, 2011, Immunology and cell biology.

Mesothelioma Tumor Cells Modulate Dendritic Cell Lipid Content, Phenotype and Function

C. Mamotte, D. Nelson, C. Jackaman, 2015, PloS one.

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells

S. Cornwall, A. Lew, B. Robinson, 2009, European Respiratory Journal.

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

D. Nelson, D. Dye, C. Jackaman, 2014, AGE.

Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?

D. Nelson, C. Jackaman, 2014, Experimental Gerontology.

Rescue of skeletal muscle alpha-actin-null mice by cardiac ( fetal ) alpha-actin

K. Davies, G. Morahan, S. Clément, 2017 .

O.24 Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies

K. Davies, G. Ravenscroft, N. Laing, 2011, Neuromuscular Disorders.

Rescue of skeletal muscle α-actin–null mice by cardiac (fetal) α-actin

K. Davies, G. Morahan, S. Clément, 2009, The Journal of cell biology.

Aging and cancer: The role of macrophages and neutrophils

P. Metharom, F. Pixley, D. Nelson, 2017, Ageing Research Reviews.

Vasculature: A Novel Mechanism for IL-2 Tumor Cells and Tumor-Associated T Cells That Mediate Destruction of + CD8IL-2 Intratumoral Immunotherapy Enhances

B. Robinson, D. Nelson, C. Jackaman, 2003 .

IL-2 Intratumoral Immunotherapy Enhances CD8+ T Cells That Mediate Destruction of Tumor Cells and Tumor-Associated Vasculature: A Novel Mechanism for IL-2 1

B. Robinson, D. Nelson, C. Jackaman, 2003, The Journal of Immunology.

Intratumoral Poly-N-Acetyl Glucosamine-Based Polymer Matrix Provokes a Prolonged Local Inflammatory Response That, When Combined with IL-2, Induces Regression of Malignant Mesothelioma in a Murine Model

B. Robinson, D. Nelson, A. Currie, 2005, Journal of immunotherapy.

IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase.

B. Robinson, D. Nelson, C. Jackaman, 2012, International immunology.

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses

D. Nelson, C. Jackaman, 2012, Cancer Immunology, Immunotherapy.

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

M. Grounds, F. Pixley, D. Nelson, 2018, Front. Genet..

Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma

F. Pixley, D. Nelson, L. Duong, 2022, Frontiers in Aging.

Murine mesothelioma induces locally-proliferating IL-10+TNF-α+CD206−CX3CR1+ M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy

D. Nelson, C. Jackaman, Joanne K Gardner, 2016, Oncoimmunology.

Rapid Copper Acquisition by Developing Murine Mesothelioma: Decreasing Bioavailable Copper Slows Tumor Growth, Normalizes Vessels and Promotes T Cell Infiltration

D. Nelson, C. Jackaman, A. Crowe, 2013, PloS one.

Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T‐ and B‐cell zones

M. Grounds, T. Shavlakadze, P. Metharom, 2018, Immunology and cell biology.

Dissociated flexor digitorum brevis myofiber culture system--a more mature muscle culture system.

S. Clément, G. Ravenscroft, N. Laing, 2007, Cell motility and the cytoskeleton.

Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution

D. Nelson, C. Jackaman, 2010, Cancer Gene Therapy.

Sarcostemma viminale activates macrophages to a pro-inflammatory phenotype

D. Nelson, C. Jackaman, B. Brestovac, 2015, Comparative Clinical Pathology.

Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules

C. Mamotte, D. Nelson, C. Jackaman, 2017, Ageing Research Reviews.

Multiple Osmotic Stress Responses in Acidihalobacter prosperus Result in Tolerance to Chloride Ions

D. Holmes, M. Dopson, E. Watkin, 2017, Front. Microbiol..

Actin Nemaline Myopathy Mouse Reproduces Disease, Suggests Other Actin Disease Phenotypes and Provides Cautionary Note on Muscle Transgene Expression

K. Davies, G. Ravenscroft, N. Laing, 2011, PloS one.

Chronic stress and Alzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia

S. Laws, G. Verdile, V. Villemagne, 2021, Biological reviews of the Cambridge Philosophical Society.

Novel application of flow cytometry: determination of muscle fiber types and protein levels in whole murine skeletal muscles and heart.

S. Clément, G. Ravenscroft, N. Laing, 2007, Cell Motility and the Cytoskeleton.

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

S. Dhaliwal, D. Nelson, C. Jackaman, 2015, Immunity & Ageing.

The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy

C. Mamotte, D. Nelson, C. Jackaman, 2018, Front. Med..

Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors

A. Suhrbier, B. Robinson, D. Nelson, 2006, Cancer Immunology, Immunotherapy.

Lipid-laden partially-activated plasmacytoid and CD4−CD8α+ dendritic cells accumulate in tissues in elderly mice

C. Mamotte, D. Nelson, C. Jackaman, 2014, Immunity & Ageing.

Oxidation of commercial (α-type) zein with hydrogen peroxide improves its hydration and dramatically increases dough extensibility even below its glass transition temperature

Janet Taylor, C. Jackaman, John R. N. Taylor, 2016 .

Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8+ T cells in vivo

A. Nowak, D. Nelson, C. Jackaman, 2012, Cancer Immunology, Immunotherapy.

CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

S. Dhaliwal, P. Metharom, D. Nelson, 2019, Oncoimmunology.

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.

A. Lew, B. Robinson, D. Nelson, 2008, International immunology.

Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation

A. Musk, C. Mamotte, S. Cornwall, 2018, PloS one.

IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

D. Nelson, D. Dye, C. Jackaman, 2014, AGE.

Ex-vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-associated sensory neuropathy

P. Price, C. Cherry, P. Kamerman, 2017, AIDS.

Aged garlic extract as a potential prophylactic to reduce the progression of endometriosis and associated pain burden

D. Kerr, C. Jackaman, V. Lam, 2022, Frontiers in Pain Research.

Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential

A. Forrest, R. Lister, M. Febbraio, 2022, bioRxiv.

Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy

J. Papadimitriou, P. Kamerman, Silvia Lee, 2023, Journal of neurovirology.

Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease.

P. Price, J. Papadimitriou, C. Mclean, 2021, Experimental and molecular pathology.

P2.50 Discovery of novel proteins, polyalanine and pre-B-cell leukaemia transcription factor 2 (PBX2), upregulated in inflammatory myopathies

B. Brais, G. Ravenscroft, N. Laing, 2010, Neuromuscular Disorders.

Rescue of skeletal muscle α-actin–null mice by cardiac (fetal) α-actin

K. Davies, G. Morahan, S. Clément, 2009, The Journal of cell biology.