R. Pappu

发表

An essential role for BLNK in human B cell development.

D. Campana, E. Coustan-Smith, M. Conley, 1999, Science.

TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers

D. Yan, P. Caplazi, J. Grogan, 2013, Mucosal Immunology.

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.

S. Coughlin, E. Camerer, J. Wong, 2009, The Journal of clinical investigation.

Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase.

A. Satterthwaite, O. Witte, A. Chan, 2003, International immunology.

Requirement for B cell linker protein (BLNK) in B cell development.

A. Cheng, A. Chan, C. Chiu, 1999, Science.

IL-13 mediates IL-33-dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells.

Z. Modrušan, Alexander R. Abbas, R. Soriano, 2015, The Journal of allergy and clinical immunology.

Maternal selenium status in pregnancy , offspring glutathione peroxidase 4 genotype , and childhood asthma

B. Yaspan, P. Lupardus, PhDb, 2018 .

Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.

D. Yan, Min Xu, Wyne P. Lee, 2017, The Journal of allergy and clinical immunology.

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Z. Modrušan, W. Ouyang, Harinder Singh, 2011, Nature Immunology.

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells.

T. Kurosaki, A. Iwamatsu, K. Okawa, 1999, Immunity.

Contribution of Bone Marrow–Derived Cells Associated With Brain Angiogenesis Is Primarily Through CD69+

W. Young, R. Gabriel, Guo-Yuan Yang, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Mice deficient in NRROS show abnormal microglial development and neurological disorders

K. Scearce-Levie, W. Ouyang, J. Hackney, 2017, Nature Immunology.

Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial*

G. Martin, J. Galanter, T. Buchman, 2022, Critical care medicine.

Design and Evaluation of Highly-Selective Human Immunoproteasome Inhibitors Reveals a Compensatory Process that Preserves Immune Cell Viability.

S. Steinbacher, M. Augustin, Celine Eidenschenk, 2019, Journal of medicinal chemistry.

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

Ying Xu, Irina Grigorova, Jason G. Cyster, 2009, The Journal of experimental medicine.

The interleukin‐17 cytokine family: critical players in host defence and inflammatory diseases

A. Sambandam, R. Pappu, V. Ramirez-Carrozzi, 2011, Immunology.

Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial.

E. Israel, I. Agache, C. Brightling, 2021, The Journal of allergy and clinical immunology.

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells

A. Zarrin, S. Warming, J. Hackney, 2020, Science Signaling.

Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma

Z. Modrušan, Alexander R. Abbas, D. Yan, 2022, Science Translational Medicine.

Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis

B. Yaspan, J. Hackney, Jianping Yin, 2022, Science Translational Medicine.

Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate

J. Cyster, S. Coughlin, Ying Xu, 2007, Science.

Regulation of antigen receptor function by protein tyrosine kinases.

G. Waksman, K. Fütterer, A. Chan, 1999, Progress in biophysics and molecular biology.

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76.

B. Mayer, J. Chernoff, J. Chernoff, 1998, Immunity.

Targeting interleukin-33 and thymic stromal lymphopoietin pathways for novel pulmonary therapeutics in asthma and COPD

K. Chung, R. Pappu, M. Grimbaldeston, 2023, European Respiratory Review.

Epstein-Barr Virus Latent Membrane Protein 2a (Lmp2a) Employs the Slp-65 Signaling Module

R. Longnecker, M. Merchant, A. Chan, 2001, The Journal of experimental medicine.

Regulation of epithelial immunity by IL-17 family cytokines.

S. Rutz, W. Ouyang, R. Pappu, 2012, Trends in immunology.

The IL-17 Family Cytokines in Immunity and Disease

W. Ouyang, R. Pappu, V. Ramirez-Carrozzi, 2010, Journal of Clinical Immunology.

BLNK Required for Coupling Syk to PLCγ2 and Rac1-JNK in B Cells

Andrew C. Chan, T. Kurosaki, A. Iwamatsu, 1999 .

Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts

H. Collard, J. Egen, Z. Modrušan, 2014, The Journal of Immunology.

Obligate role for Rock1 and Rock2 in adult stem cell viability and function

Patrick S. Chang, Z. Modrušan, J. Hackney, 2023, Heliyon.

Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes

W. Ouyang, J. Hackney, A. Sambandam, 2019, The Journal of Immunology.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1

Meijuan Zhou, Min Xu, Zora Modrusan, 2013, Nature Immunology.

This information is current as Fibroblasts Does Not Activate Signaling in Human Lung Mediated Responses but − Attenuates IL-13 2 α Endogenously Expressed IL-13 R

H. Collard, J. Egen, Z. Modrušan, 2014 .

30 Years of Biotherapeutics Development-What Have We Learned?

A. Chan, N. Ghilardi, J. Arron, 2020, Annual review of immunology.

Functional analysis of protective IL1RL1 variants associated with asthma risk.

B. Yaspan, P. Lupardus, R. Pappu, 2015, The Journal of allergy and clinical immunology.

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

D. McDonald, J. Cyster, S. Coughlin, 2009, The Journal of experimental medicine.