F. Castelli

发表

Combinatory therapy targeting mitochondrial oxidative phosphorylation improves efficacy of IDH mutant inhibitors in acute myeloid leukemia

F. Jourdan, M. Carroll, M. Konopleva, 2019, bioRxiv.

Interferon Regulatory Factor 5 represses oxidative respiration in human and murine macrophages by inhibition of mitochondrial matrix protein GHITM

J. Rieusset, Sophie Lemoine, C. Blugeon, 2021 .

Differential capacity of T cell priming in naive donors of promiscuous CD4+ T cell epitopes of HCV NS3 and Core proteins

H. Zarour, A. Ménez, B. Maillère, 2007, European journal of immunology.

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.

E. Chevet, A. Chatziioannou, J. Ricci, 2018, Cell metabolism.

The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer

C. Dumontet, A. Rossary, F. Caldefie‐Chézet, 2021, Frontiers in Cell and Developmental Biology.

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

K. Stegmaier, E. Clappier, H. Dombret, 2022, Leukemia.

Chronic Consumption of Cocoa Rich in Procyanidins Has a Marginal Impact on Gut Microbiota and on Serum and Fecal Metabolomes in Male Endurance Athletes.

F. Fenaille, F. Castelli, Mariangela Tabone, 2022, Journal of agricultural and food chemistry.

Identification of a novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA

I. Gutsche, C. Brochier-Armanet, F. Fenaille, 2018, bioRxiv.

Metabolomic Investigation of Staphylococcus aureus Antibiotic Susceptibility by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry.

C. Junot, F. Fenaille, F. Castelli, 2018, Methods in molecular biology.

Peptide-Binding Specificity Molecule , Defines a New Supertype of HLA-DP 4 , the Most Frequent HLA II

H. Zarour, A. Ménez, B. Maillère, 2002 .

The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors

E. Tartour, Elodie Marcon, H. Nozach, 2015, The Journal of Immunology.

Both Healthy and Cancer Donors by Pre-Existing Naive and Memory Cells in CD4 T Cell Epitopes Differently Recognized The Tumor Antigen Cyclin B1 Hosts Multiple

E. Tartour, Elodie Marcon, H. Nozach, 2015 .

In vitro human CD4+ T cell response to the vaccinia protective antigens B5R and A33R.

B. Maillère, F. Castelli, N. Szely, 2009, Molecular immunology.

One NY-ESO-1-Derived Epitope That Promiscuously Binds to Multiple HLA-DR and HLA-DP4 Molecules and Stimulates Autologous CD4+ T Cells from Patients with NY-ESO-1-Expressing Melanoma1

V. Brusic, J. Kirkwood, H. Zarour, 2005, The Journal of Immunology.

NY-ESO-1-Expressing Melanoma T Cells from Patients with + Autologous CD 4 and HLA-DP 4 Molecules and Stimulates Promiscuously Binds to Multiple HLA-DR One NY-ESO-1-Derived Epitope That

V. Brusic, J. Kirkwood, H. Zarour, 2005 .

Emerging principles for the design of promiscuous HLA‐DR‐restricted peptides: an example from the major bee venom allergen

A. Ménez, B. Maillère, C. Texier, 2002, European journal of immunology.

The Human Meconium Metabolome and Its Evolution during the First Days of Life

C. Junot, A. Paris, F. Fenaille, 2022, Metabolites.

The Signal Peptide of the Tumor-shared Antigen Midkine Hosts CD4+ T Cell Epitopes*

B. Maillère, F. Castelli, Jérôme Kerzerho, 2013, The Journal of Biological Chemistry.

AntigenBiomarker Midkine Is a Tumor-Shared The Angiogenic Growth Factor and

E. Tartour, F. Lang, F. Castelli, 2010 .

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF.

B. Colsch, C. Junot, F. Nevens, 2019, Journal of hepatology.

A Novel Subfamily of Bacterial AAT-Fold Basic Amino Acid Decarboxylases and Functional Characterization of Its First Representative: Pseudomonas aeruginosa LdcA

I. Gutsche, C. Brochier-Armanet, F. Fenaille, 2018, Genome biology and evolution.

Assessing the role of amino acids in systemic inflammation and organ failure in patients with ACLF.

C. Junot, R. Moreau, R. Jalan, 2020, Journal of hepatology.

Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis ☆

B. Colsch, C. Junot, M. Vinaixa, 2021 .

Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

P. Bénit, P. Gestraud, B. Colsch, 2022, Frontiers in Oncology.

Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling

J. Rieusset, C. Blugeon, S. Lameiras, 2022, Nature Communications.

Using a multiomics approach to unravel a septic shock specific signature in skeletal muscle

O. Langeron, P. Rocheteau, A. Bouglé, 2022, Scientific Reports.

Late-onset glaucoma in Yap conditional knockout mouse

M. Locker, M. Perron, E. Grellier, 2022, bioRxiv.

Novel promiscuous HLA‐DQ HIV Nef peptide that induces IFN‐γ‐producing memory CD4+ T cells

E. Hachulla, B. Maillère, F. Castelli, 2002 .

Prediction of CD4(+) T cell epitopes restricted to HLA-DP4 molecules.

A. Ménez, B. Maillère, M. Busson, 2006, Journal of immunological methods.

HLA-DP4, the Most Frequent HLA II Molecule, Defines a New Supertype of Peptide-Binding Specificity1

Alain Sanson, H. Zarour, A. Ménez, 2002, The Journal of Immunology.

Development of an Untargeted Metabolomics Strategy to Study the Metabolic Rewiring of Dendritic Cells upon Lipopolysaccharide Activation

C. Junot, F. Fenaille, F. Castelli, 2023, Metabolites.

Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

C. Junot, G. Rosati, T. Lefèbvre, 2021, Analytical and Bioanalytical Chemistry.

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

F. Jourdan, M. Carroll, M. Konopleva, 2021, The Journal of experimental medicine.

Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

A. Zdebik, F. Fenaille, Rossella Conti, 2021, Proceedings of the National Academy of Sciences.

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

C. Junot, L. Linares, J. Portais, 2016, The Journal of experimental medicine.

Hierarchy of CD4 T Cell Epitopes of the ANRS Lipo5 Synthetic Vaccine Relies on the Frequencies of Pre-Existing Peptide-Specific T Cells in Healthy Donors

Y. Lévy, O. Schwartz, B. Maillère, 2013, The Journal of Immunology.

Cross-Reactive CD4+ T Cells against One Immunodominant Tumor-Derived Epitope in Melanoma Patients1

J. Kirkwood, H. Zarour, M. Amicosante, 2007, The Journal of Immunology.

Melanoma Patients inImmunodominant Tumor-Derived Epitope T Cells against One + Cross-Reactive CD 4

J. Kirkwood, H. Zarour, M. Amicosante, 2007 .

Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

F. Fenaille, A. Prignon, P. Richette, 2020, Annals of the Rheumatic Diseases.

Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D

L. BenMohamed, B. Maillère, F. Castelli, 2008, Clinical and Vaccine Immunology.

Midkine as a Tumor-Shared Antigen

B. Maillère, F. Castelli, Jérôme Kerzerho, 2012 .

Determination of a HLA II Promiscuous Peptide Cocktail as Potential Vaccine Against EBV Latency II Malignancies

Claude Auriault, S. Depil, B. Maillère, 2007, Journal of immunotherapy.

Selective identification of HLA-DP4 binding T cell epitopes encoded by the MAGE-A gene family

Christine Almunia, Dominique Charron, H. Zarour, 2007, Cancer Immunology, Immunotherapy.

Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations

V. Pancaldi, C. Récher, J. Sarry, 2021, Cancers.

NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

V. Brusic, J. Kirkwood, H. Zarour, 2002, Cancer research.

Bee Venom Phospholipase A2, a Good “Chauffeur” for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1

A. Ménez, B. Maillère, D. Gillet, 2013, PloS one.

Immunoprevalence of the CD4+ T‐cell response to HIV Tat and Vpr proteins is provided by clustered and disperse epitopes, respectively

D. Houitte, S. Muller, B. Maillère, 2008, European journal of immunology.

The Angiogenic Growth Factor and Biomarker Midkine Is a Tumor-Shared Antigen

E. Tartour, B. Maillère, F. Lang, 2010, The Journal of Immunology.

Human CD4 T cell epitopes selective for Vaccinia versus Variola virus

B. Maillère, F. Castelli, Aurore Besse, 2012, Molecular immunology.

Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men

F. Jourdan, E. Thévenot, B. Colsch, 2021, EBioMedicine.

ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Y. Hérault, T. Sorg, C. Médigue, 2021, Scientific Data.

Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches

C. Delacourt, M. Moroldo, F. Fenaille, 2023, Frontiers in Immunology.

Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow’s milk

C. Junot, C. Dupont, D. De boissieu, 2018, Clinical and Translational Allergy.

Identification of the Major Degradation Pathways of Selumetinib

N. Yagoubi, B. Do, F. Castelli, 2022, Pharmaceutics.

Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis.

B. Colsch, C. Junot, M. Vinaixa, 2021, Journal of hepatology.

Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

F. Fenaille, D. Rémond, S. Polakof, 2022, Journal of Physiology and Biochemistry.

Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)

C. Trautwein, T. Berg, C. Junot, 2023, Gut.

The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes

F. Fenaille, F. Castelli, Mariangela Tabone, 2021, Scientific reports.

Immune components of early breastmilk: Association with maternal factors and with reported food allergy in childhood

B. Heude, C. Junot, M. Charles, 2019, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Metabolomics in the understanding and management of hepatic encephalopathy.

B. Colsch, M. Rudler, D. Thabut, 2021, Analytical biochemistry.

Novel promiscuous HLA-DQ HIV Nef peptide that induces IFN-gamma-producing memory CD4+ T cells.

E. Hachulla, B. Maillère, C. Auriault, 2002, Clinical and experimental immunology.

Scaling-up metabolomics: Current state and perspectives

F. Jourdan, E. Thévenot, C. Junot, 2023, TrAC Trends in Analytical Chemistry.