D. Hutt

发表

Expanding proteostasis by membrane trafficking networks.

W. Balch, D. Hutt, 2013, Cold Spring Harbor perspectives in biology.

Correcting the F508del-CFTR variant by modulating eukaryotic translation initiation factor 3–mediated translation initiation

A. Su, S. Loguercio, W. Balch, 2018, The Journal of Biological Chemistry.

The proteostasis boundary in misfolding diseases of membrane traffic

E. Powers, W. Balch, D. Hutt, 2009, FEBS letters.

A Chaperone Trap Contributes to the Onset of Cystic Fibrosis

J. Yates, W. Balch, Abbas Razvi, 2012, PloS one.

Histone Deacetylase Inhibitor (HDACi) Suberoylanilide Hydroxamic Acid (SAHA)-mediated Correction of α1-Antitrypsin Deficiency*

T. Flotte, P. Szajner, W. Balch, 2012, The Journal of Biological Chemistry.

Proteostasis and Energetics as Proteome Hallmarks of Aging and Influenza Challenge in Pulmonary Disease

J. Sznajder, S. Loguercio, R. Morimoto, 2019, bioRxiv.

Proteins and Functions of the Endoplasmic Reticulum The Contribution of Systematic Approaches to Characterizing the

D. Pincus, J. Weissman, M. Schuldiner, 2013 .

A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.

S. Loguercio, W. Balch, A. Campos, 2018, Journal of molecular biology.

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability*

Monica A. Chalfant, J. Brodsky, W. Balch, 2012, Journal of Biological Chemistry.

Synaptotagmin VI and VIII and Syntaxin 2 Are Essential for the Mouse Sperm Acrosome Reaction*

J. Ngsee, J. Baltz, D. Hutt, 2005, Journal of Biological Chemistry.

Synaptotagmin VIII Is Localized to the Mouse Sperm Head and May Function in Acrosomal Exocytosis1

R. Cardullo, J. Ngsee, J. Baltz, 2002, Biology of reproduction.

Diacylglycerol is the preferred substrate in high density lipoproteins for human hepatic lipase.

C. Coffill, D. Sparks, D. Hutt, 1997, Journal of lipid research.

ResponseReticulum Stress Sensing in the Unfolded Protein

D. Pincus, J. Olzmann, M. Aebi, 2014 .

PRA1 Inhibits the Extraction of Membrane-bound Rab GTPase by GDI1*

J. Ngsee, Li-Hsin Chang, D. Hutt, 2000, The Journal of Biological Chemistry.

Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy

W. Balch, R. Frizzell, Sanjay Mishra, 2018, The Journal of Biological Chemistry.

Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis

John D. Venable, J. Riordan, J. Yates, 2006, Cell.

Management of Hsp90-Dependent Protein Folding by Small Molecule Targeting the Aha1 Co-Chaperone

B. Tait, W. Balch, J. Gestwicki, 2018, bioRxiv.

The Proteome in Balance

W. Balch, D. Hutt, 2010, Science.

Small Molecule Proteostasis Regulators for Protein Conformational Diseases

Monica A. Chalfant, D. Garza, R. Morimoto, 2011, Nature chemical biology.

Individualized Management of Genetic Diversity in Niemann-Pick C1 through Modulation of the Hsp70 Chaperone System.

W. Balch, J. Gestwicki, D. Hutt, 2019, Human molecular genetics.

Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

E. Masliah, D. Garza, R. Morimoto, 2014, PLoS biology.

Expanding proteostasis by membrane trafficking networks.

W. Balch, D. Hutt, 2013, Cold Spring Harbor perspectives in medicine.

CFTR processing, trafficking and interactions.

Hugo M. Botelho, N. Pedemonte, M. Amaral, 2020, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

HDAC Inhibitors Rescue Multiple Disease-Causing CFTR Variants

W. Balch, D. Hutt, F. Anglès, 2018, bioRxiv.

The Histone Deacetylase Inhibitor, Vorinostat, Represses Hypoxia Inducible Factor 1 Alpha Expression through Translational Inhibition

D. M. Roth, H. Vignaud, D. Hutt, 2014, PloS one.

Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid

W. Balch, D. Hutt, Kanagaraj Subramanian, 2020, The Journal of Biological Chemistry.

Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process

W. Balch, F. Porter, D. Hutt, 2019, Nature Communications.

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

W. Balch, D. Hutt, Kanagaraj Subramanian, 2019, bioRxiv.

Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells[S]

F. Maxfield, W. Balch, N. Pipalia, 2017, Journal of Lipid Research.

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.

John R Yates, Gerard Manning, Yoshihiro Matsumura, 2010, Nature chemical biology.

Managing the Spatial Covariance of Genetic Diversity in Niemann-Pick C1 Through Modulation of the Hsp70 Chaperone System

J. Gestwicki, D. Hutt, H. Shao, 2018, bioRxiv.

Emergent properties of proteostasis in managing cystic fibrosis.

W. Balch, D. M. Roth, D. Hutt, 2011, Cold Spring Harbor perspectives in biology.

Effect of acylglyceride content on the structure and function of reconstituted high density lipoprotein particles.

C. Coffill, D. Sparks, D. Hutt, 2001, Journal of lipid research.

Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR.

Monica A. Chalfant, M. Ghadiri, W. Balch, 2011, ACS medicinal chemistry letters.

Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation.

D. M. Roth, C. Marchal, D. Hutt, 2017, Methods in molecular biology.

Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.

W. Balch, J. Gestwicki, J. Sivils, 2020, Cell chemical biology.

Emergent properties of proteostasis in managing cystic fibrosis.

W. Balch, D. M. Roth, D. Hutt, 2011, Cold Spring Harbor perspectives in biology.

Rab1b silencing using small interfering RNA for analysis of disease-specific function.

W. Balch, D. Hutt, 2008, Methods in enzymology.

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability*

Monica A. Chalfant, J. Brodsky, W. Balch, 2012, The Journal of Biological Chemistry.