Greet De Baets

发表

α-Galactosidase Aggregation Is a Determinant of Pharmacological Chaperone Efficacy on Fabry Disease Mutants*

S. Rudyak, F. Rousseau, R. Gallardo, 2012, The Journal of Biological Chemistry.

High‐throughput discovery of functional disordered regions: investigation of transactivation domains

M Madan Babu, Greet De Baets, M. Babu, 2018, Molecular systems biology.

Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability

K. Sleegers, C. van Broeckhoven, S. Engelborghs, 2019, Acta Neuropathologica.

A genome-wide sequence-structure analysis suggests aggregation gatekeepers constitute an evolutionary constrained functional class.

F. Rousseau, J. van Durme, Joost Schymkowitz, 2014, Journal of molecular biology.

Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits.

Guangdi Li, A. Vandamme, F. Rousseau, 2014, Virology.

Structural hot spots for the solubility of globular proteins

Jacinte Beerten, H. Wilkinson, F. De Smet, 2016, Nature Communications.

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

K. Verstrepen, C. van Broeckhoven, W. Robberecht, 2016, Scientific Reports.

Assessing computational predictions of the phenotypic effect of cystathionine‐beta‐synthase variants

Silvio C. E. Tosatto, Predrag Radivojac, Mauno Vihinen, 2019, Human mutation.

Sequence-dependent Internalization of Aggregating Peptides*

Frederic Rousseau, Rodrigo Gallardo, Joost Schymkowitz, 2014, The Journal of Biological Chemistry.

Selectivity of aggregation-determining interactions.

W. Jonckheere, H. Wilkinson, F. Rousseau, 2015, Journal of molecular biology.

Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool*

B. de Strooper, J. Rozenski, V. Subramaniam, 2012, The Journal of Biological Chemistry.

A comparative analysis of the aggregation behavior of amyloid‐β peptide variants

H. Wenschuh, V. Subramaniam, J. Schymkowitz, 2012, FEBS letters.

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

C. van Broeckhoven, S. Engelborghs, R. Vandenberghe, 2015, Neurology.

The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells

D. Lambrechts, K. Nilsson, I. Vergote, 2020, bioRxiv.

Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V.

Nikolaos N. Louros, W. Robberecht, Jacinte Beerten, 2019, Protein engineering, design & selection : PEDS.

Solubis: a webserver to reduce protein aggregation through mutation.

Frederic Rousseau, Rodrigo Gallardo, Joost Schymkowitz, 2016, Protein engineering, design & selection : PEDS.

Predicting aggregation-prone sequences in proteins.

Joost Schymkowitz, Frederic Rousseau, Greet De Baets, 2014, Essays in biochemistry.

Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation

K. Ligon, S. Aerts, Jie Xu, 2020, Cells.

Nuclear inclusion bodies of mutant and wild‐type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation

P. A. van den Brandt, K. Ligon, F. De Smet, 2017, The Journal of pathology.

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Silvio C. E. Tosatto, Julius O. B. Jacobsen, Nicholas A. Sinnott-Armstrong, 2024, Genome biology.

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Nicholas A. Sinnott-Armstrong, Jonathan M. Mudge, Hui Ting Grace Yeo, 2022, Genome biology.