M. Jordan

A. Vinks, K. Myers, S. Davies, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The successful use of alemtuzumab for treatment of steroid‐refractory acute graft‐versus‐host disease in pediatric patients

K. Myers, S. Davies, P. Mehta, 2014, Pediatric transplantation.

Treatment of refractory hemophagocytic lymphohistiocytosis with emapalumab despite severe concurrent infections.

M. Jordan, Q. Bin, C. de Min, 2019, Blood advances.

NEW INSIGHTS INTO THE PATHOPHYSIOLOGY OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

M. Jordan, K. Risma, 2012 .

Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.

Michael M. Henry, F. Locatelli, T. Garrington, 2020, The New England journal of medicine.

Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH.

A. Mattman, M. Jordan, A. Hayden, 2017, Blood advances.

IDENTIFICATION OF A PHOSPHOINOSITIDE 3-KINASE (PI-3K) P110DELTA (PIK3CD) DEFICIENT INDIVIDUAL

M. Jordan, 2013 .

Prolonged Remission Achieved in a Relapsing Idiopathic Multicentric Castleman Disease Patient with a Novel, Targeted Treatment Approach

V. Krymskaya, S. Pierson, D. Shilling, 2017 .

Malignancy-associated haemophagocytic lymphohistiocytosis.

M. Jordan, A. Setiadi, Luke Y. C. Chen, 2022, The Lancet. Haematology.

JAK inhibition for murine HLH requires complete blockade of IFNg signaling and is limited by toxicity of JAK2 inhibition.

M. Jordan, Vandana Chaturvedi, Nora Lakes, 2021, Blood.

Molecular and Cellular Mechanisms of Mycobacterium avium-Induced Thymic Atrophy

R. Appelberg, M. Flórido, M. Borges, 2012, The Journal of Immunology.

Atrophy -Induced Thymic Mycobacterium avium Molecular and Cellular Mechanisms of

M. Flórido, M. Borges, M. Jordan, 2012 .

Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults

J. V. van Laar, R. Machowicz, A. Horne, 2021, Critical care medicine.

Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function.

A. Herr, M. Jordan, J. Sumegi, 2009, Blood.

Prospective two center study of CD38 bright CD8+ effector memory T-cells as a predictor of acute GVHD

R. Garzon, Y. Efebera, S. Devine, 2022, Transplantation Reports.

hemolytic anemia in a mouse model Liposomal clodronate as a novel agent for treating autoimmune

P. Marrack, J. Kappler, N. Rooijen, 2013 .

Real-Time Detection of CTL Function Reveals Distinct Patterns of Caspase Activation Mediated by Fas versus Granzyme B

A. Filipovich, M. Jordan, Braeden L. Butler, 2014, The Journal of Immunology.

BActivation Mediated by Fas versus Granzyme Reveals Distinct Patterns of Caspase Real-Time Detection of CTL Function

A. Filipovich, M. Jordan, Braeden L. Butler, 2014 .

Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inﬂammation and Chemokine Production (cid:1)

David A Hildeman, P. Tripathi, A. Sholl, 2009 .

Daratumumab for the management of autoimmune cytopenias in children and young adults: a case series

S. Davies, P. Mehta, M. Jordan, 2021, British journal of haematology.

Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease

Andrew J. Oler, Smita Y. Patel, Ivan K. Chinn, 2019, The Journal of allergy and clinical immunology.

This information is current as Lymphohistiocytosis Disorder Hemophagocytic Cells To Control the Immunoregulatory Etoposide Selectively Ablates Activated T

David A Hildeman, J. Katz, M. Jordan, 2013 .

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes.

A. Fischer, H. Kanegane, P. Veys, 2013, Blood.

Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD

S. Choo, S. Ehl, A. Worth, 2021, Journal of clinical immunology.

Bortezomib for refractory autoimmunity in pediatrics.

S. Davies, S. Jodele, A. Filipovich, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Macrophage‐Lineage Cells Negatively Regulate the Hematopoietic Stem Cell Pool in Response to Interferon Gamma at Steady State and During Infection

M. Jordan, Amanda McCabe, K. MacNamara, 2015, Stem cells.

Peripheral Blood CD38 Bright CD8+ Effector Memory T Cells Predict Acute Graft-versus-Host Disease.

S. Davies, D. Marmer, A. Filipovich, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia

H. Heslop, C. Bollard, D. Hagin, 2021, Blood advances.

HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis

Y. Hayashi, Xiaomei Yan, Lingyun Wu, 2017, Haematologica.

Mixed hematopoietic or T-cell chimerism above a minimal threshold restores perforin-dependent immune regulation in perforin-deficient mice.

M. Jordan, C. Terrell, 2013, Blood.

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis.

B. Burkhardt, A. Schulz, S. Ehl, 2016, Blood.

Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation

S. Davies, M. Jordan, Ashish R. Kumar, 2020, Journal of Clinical Immunology.

Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation

S. Davies, M. Jordan, Ashish R. Kumar, 2020, Journal of clinical immunology.

Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation.

S. Davies, P. Mehta, Mi‐Ok Kim, 2010, Blood.

Salvage therapy for refractory hemophagocytic lymphohistiocytosis: A review of the published experience

K. Nichols, M. Jordan, Ashish R. Kumar, 2017, Pediatric blood & cancer.

Reduced‐intensity conditioning haematopoietic cell transplantation for haemophagocytic lymphohistiocytosis: an important step forward

A. Filipovich, M. Jordan, R. Marsh, 2011, British journal of haematology.

Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis.

G. Lucchini, P. Veys, A. Worth, 2018, Blood.

STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America

N. Satake, Kejian Zhang, A. Filipovich, 2010, Pediatric blood & cancer.

CD38 bright CD8+ T-cells Associated with the Development of Acute GVHD are Activated, Proliferating, and Cytotoxic Trafficking Cells.

C. Lutzko, S. Davies, M. Jordan, 2019, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

HLH: birds of a feather flock together.

M. Jordan, 2022, Blood.

Alternate-day micafungin antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study.

A. Vinks, S. Davies, P. Mehta, 2010, Biology of Blood and Marrow Transplantation.

Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin Deficiency

A. Schambach, P. Malik, A. Thrasher, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Revised Classification of Histiocytoses and Neoplasms of the Macrophage-dendritic Cell Lineages Histiocyte and Dendritic Cell Lineages the " L " (langerhans) Group

A. Fischer, B. Rollins, O. Abdel-Wahab, 2022 .

Post-Transplant CD34+ Selected Stem Cell "Boost" for Mixed Chimerism after Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation in Children and Young Adults with Primary Immune Deficiencies.

S. Davies, M. Jordan, P. Khandelwal, 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

High Level of Perforin Expression Is Required for Effective Correction of Hemophagocytic Lymphohistiocytosis.

P. Malik, P. Arumugam, S. Tiwari, 2016, Human gene therapy.

HIGH LEVEL OF PERFORIN EXPRESSION PER CELL IS REQUIRED FOR EFFECTIVE CORRECTION OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

P. Malik, P. Arumugam, S. Tiwari, 2016 .

Dying to protect: cell death and the control of T‐cell homeostasis

David A Hildeman, J. Katz, M. Jordan, 2017, Immunological reviews.

Undermining Protective Immunity Eliminating Encephalitogenic T Cells without

David A Hildeman, J. Katz, M. Jordan, 2017 .

Eliminating Encephalitogenic T Cells without Undermining Protective Immunity

David A Hildeman, J. Katz, M. Jordan, 2014, The Journal of Immunology.

Reduced-intensity conditioning hematopoietic cell transplantation is an effective treatment for patients with SLAM-associated protein deficiency/X-linked lymphoproliferative disease type 1.

S. Davies, A. Filipovich, M. Jordan, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases

Michael M. Henry, M. Hermiston, P. Andreassen, 2017, Proceedings of the National Academy of Sciences.

Anti‐CD52 antibody, alemtuzumab, binds to Langerhans cells in Langerhans cell histiocytosis

R. Jaffe, M. Jordan, K. McClain, 2005, Pediatric blood & cancer.

The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis

W. Al-Herz, A. Gennery, S. Pai, 2015, Haematologica.

An intermediate alemtuzumab schedule reduces the incidence of mixed chimerism following reduced-intensity conditioning hematopoietic cell transplantation for hemophagocytic lymphohistiocytosis.

K. Myers, S. Davies, P. Mehta, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Chediak–Higashi syndrome with early developmental delay resulting from paternal heterodisomy of chromosome 1

W. Gahl, T. Markello, W. Westbroek, 2010, American journal of medical genetics. Part A.

Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society.

S. Ehl, K. Nichols, R. Machowicz, 2018, The journal of allergy and clinical immunology. In practice.

Hematopoietic cell transplantation for hemophagocytic lymphohistiocytosis: a journey of a thousand miles begins with a single (big) step

A. Filipovich, M. Jordan, M. Jordan, 2008, Bone Marrow Transplantation.

Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis

M. Jordan, K. Baker, 2018 .

Incidence and Outcomes of Central Nervous System Hemophagocytic Lymphohistiocytosis Relapse after Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation.

S. Davies, M. Jordan, Ashish R. Kumar, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Elevated Granzyme B in Cytotoxic Lymphocytes is a Signature of Immune Activation in Hemophagocytic Lymphohistiocytosis

Kejian Zhang, A. Filipovich, J. Villanueva, 2013, Front. Immunol..

An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.

P. Marrack, J. Kappler, David A Hildeman, 2004, Blood.

Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey

L. Notarangelo, J. Walter, J. Puck, 2020, Frontiers in Immunology.

How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?

A. Horne, J. Henter, M. Jordan, 2017, Current Treatment Options in Neurology.

Hemophagocytosis causes a consumptive anemia of inflammation

J. Aliberti, P. Henson, A. Filipovich, 2011, The Journal of experimental medicine.

Emapalumab in primary haemophagocytic lymphohistiocytosis and the pathogenic role of interferon gamma: A pharmacometric model‐based approach

P. Jacqmin, E. Snoeck, M. Jordan, 2021, British journal of clinical pharmacology.

HEMATOPOIETIC STEM CELL TRANSPLANTATION RESCUES THE VASCULAR, HAEMATOLOGICAL AND IMMUNOLOGICAL PHENOTYPE IN ADENOSINE DEAMINASE 2 DEFICIENCY

S. Holland, T. Torgerson, D. Kastner, 2017 .

Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD

S. Choo, S. Ehl, A. Worth, 2021, Journal of Clinical Immunology.

KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice.

B. Aronow, P. Dexheimer, P. Malik, 2015, Blood.

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH.

J. Meller, P. S. Klein, Kejian Zhang, 2011, Blood.

with adult-onset familial hemophagocytic lymphohistiocytosis Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated

J. Meller, P. S. Klein, Kejian Zhang, 2012 .

Experience with Alemtuzumab, Fludarabine, and Melphalan Reduced-Intensity Conditioning Hematopoietic Cell Transplantation in Patients with Nonmalignant Diseases Reveals Good Outcomes and That the Risk of Mixed Chimerism Depends on Underlying Disease, Stem Cell Source, and Alemtuzumab Regimen.

K. Myers, S. Davies, P. Mehta, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Challenges in improving global outcomes for hemophagocytic lymphohistiocytosis

M. Jordan, A. Zoref-Lorenz, 2021, Pediatric hematology and oncology.

Outcomes of donor lymphocyte infusion for treatment of mixed donor chimerism after a reduced-intensity preparative regimen for pediatric patients with nonmalignant diseases.

S. Davies, A. Filipovich, M. Jordan, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

IFN-γ Signature in the Plasma Proteome Distinguishes Pediatric Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS.

Michael M. Henry, T. Nguyen, H. Wong, 2021, Blood advances.

Limitations of HLH‐2004 criteria in distinguishing malignancy‐associated hemophagocytic lymphohistiocytosis

M. Absalon, R. Lorsbach, M. Jordan, 2018, Pediatric blood & cancer.

Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production

David A Hildeman, P. Tripathi, A. Sholl, 2009, Journal of Virology.

Outcomes following hematopoietic cell transplantation for Wiskott–Aldrich syndrome

S. Davies, P. Mehta, S. Jodele, 2012, Bone Marrow Transplantation.

Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation.

S. Way, B. Vallance, M. Jordan, 2017, Cell reports.

mTOR Inhibitor Therapy Diminishes Circulating CD8+ CD28− Effector Memory T Cells and Improves Allograft Inflammation in Belatacept-refractory Renal Allograft Rejection

E. Woodle, David A Hildeman, R. Alloway, 2020, Transplantation.

α4β7 Integrin expression and blockade in pediatric and young adult gastrointestinal graft‐versus‐host disease

K. Myers, S. Davies, P. Mehta, 2021, Pediatric blood & cancer.

Thrombotic Microangiopathy Can Occur Before Transplant in Children with HLH

S. Davies, S. Jodele, M. Jordan, 2017 .

Prevalence of Viral Infections in Children Undergoing First Allogenic Hematopoietic Stem Cell Transplantation: Two Year Single Center Experience

K. Myers, S. Davies, P. Mehta, 2012 .

An improved index for diagnosis and mortality prediction in malignancy associated hemophagocytic lymphohistiocytosis.

B. Ebert, A. Nagler, S. Nikiforow, 2021, Blood.

Extending Remission and Reversing New-Onset Type 1 Diabetes by Targeted Ablation of Autoreactive T Cells

David A Hildeman, J. Katz, M. Jordan, 2018, Diabetes.

Fibrous histiocytoma of the larynx

J. Soames, M. Jordan, 1989, The Journal of Laryngology & Otology.

A Case of Chronic Lymphocytic Leukemia Complicated by Hemophagocytic Lymphohistiocytosis: Identifying the Aberrant Immune Response

M. Ellis, M. Jordan, M. Yuklea, 2022, Journal of General Internal Medicine.

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

C. Wouters, N. Wulffraat, R. Schneider, 2016, RMD Open.

Hemophagocytic lymphohistiocytosis in a female patient due to a heterozygous XIAP mutation and skewed X chromosome inactivation

S. Davies, Kejian Zhang, Jennifer R. Holle, 2015, Pediatric blood & cancer.

Modeling primary immune regulatory disorders: Ferrari or Yugo?

M. Jordan, 2017, Immunology and cell biology.

Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology

J. Woodgett, Harinder Singh, David A Hildeman, 2017, Nature Communications.

Quercetin Ameliorates XIAP Deficiency Associated Hyperinflammation.

S. Davies, P. Mehta, C. Booth, 2022, Blood.

Safety and Efficacy of Emapalumab in Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis

F. Locatelli, T. Garrington, W. Ferlin, 2018, Blood.

Discrepancies between F‐18‐FDG PET/CT findings and conventional imaging in Langerhans cell histiocytosis

M. Jordan, S. Sharp, Ashish R. Kumar, 2021, Pediatric blood & cancer.

Outcomes Following Hematopoietic Cell Transplantation for Wiskott Aldrich Syndrome

P. Mehta, Mi‐Ok Kim, S. Jodele, 2011 .

Abstracts From the 32nd Annual Meeting of the Histiocyte Society Dublin, Ireland October 17-19, 2016.

Pooja, Wright, Tracey, 2016, Pediatric Blood & Cancer.

Effects of Etomidate and Hypothermia on Cerebral Metabolism and Blood Flow in a Canine Model of Hypoperfusion

E. Allen, M. Jordan, H. Batjer, 1993, Journal of neurosurgical anesthesiology.

Loss of STAT2 may be dangerous in a world filled with viruses.

M. Jordan, 2023, The Journal of clinical investigation.

The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS)

J. Carcillo, L. Henderson, K. Nichols, 2023, Annals of the Rheumatic Diseases.

Pediatric Phase II Study of Maraviroc for Acute Graft Versus Host Disease Prophylaxis

A. Vinks, K. Myers, S. Davies, 2019, Biology of Blood and Marrow Transplantation.

A prospective pilot study of a novel alemtuzumab target concentration intervention strategy

A. Vinks, K. Myers, S. Davies, 2021, Bone Marrow Transplantation.

Dying to protect: cell death and the control of T‐cell homeostasis

David A Hildeman, J. Katz, M. Jordan, 2017, Immunological reviews.

Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages.

A. Fischer, B. Rollins, O. Abdel-Wahab, 2016, Blood.

Adolescents and Young Adults With Hemophagocytic Lymphohistiocytosis Who Undergo Allogeneic Hematopoietic Cell Transplantation Are At Increased Risk Of Mortality Compared To Younger Patients

A. Filipovich, M. Jordan, S. Chandrakasan, 2013 .

Outcome of Hematopoietic Cell Transplant for Hemophagocytic Lymphohistiocytosis in Adults: A Single Center Experience

S. Davies, A. Filipovich, M. Jordan, 2013 .

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH.

J. Meller, P. S. Klein, Kejian Zhang, 2011, Blood.

Perforin is a critical physiologic regulator of T-cell activation.

M. Jordan, K. Risma, C. Terrell, 2011, Blood.

Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function.

A. Herr, M. Jordan, J. Sumegi, 2009, Blood.

KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice.

B. Aronow, P. Dexheimer, P. Malik, 2015, Blood.

The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS)

R. Cron, D. Aletaha, S. Vastert, 2023, Arthritis & rheumatology.