J. Chee

发表

Interferon-induced guanylate-binding proteins in inflammasome activation and host defense

Pradeep Kumar, B. Kim, J. Chee, 2016, Nature Immunology.

Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens

S. Stone, J. Chee, C. Forbes, 2019, Oncoimmunology.

Transient Treg depletion enhances therapeutic anti‐cancer vaccination

R. Holt, L. Boon, J. Creaney, 2016, Immunity, inflammation and disease.

Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes.

Balasubramanian Krishnamurthy, H. Thomas, T. Kay, 2016, JCI insight.

Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes

A. Skowera, M. Peakman, H. Thomas, 2014, The Journal of Immunology.

Neo-antigen specific T cell responses indicate the presence of metastases before imaging

J. Creaney, I. Dick, J. Chee, 2019, Scientific Reports.

Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

R. Holt, T. Lassmann, A. Nowak, 2020, Frontiers in Immunology.

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

L. Boon, I. Dick, A. Nowak, 2022, Frontiers in Immunology.

Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model

J. Chee, C. Forbes, B. Foley, 2020, Epigenetics.

Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells

G. Morahan, H. Thomas, T. Kay, 2012, Diabetes.

TNF Receptor 1 Deficiency Increases Regulatory T Cell Function in Nonobese Diabetic Mice

H. Thomas, T. Kay, H. Bluethmann, 2011, The Journal of Immunology.

Malignant Pleural Effusions—A Window Into Local Anti-Tumor T Cell Immunity?

A. Nowak, R. Lake, W. Lesterhuis, 2021, Frontiers in Oncology.

BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells

A. Strasser, H. Thomas, T. Kay, 2015, Diabetes.

Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.

L. Boon, H. Thomas, T. Kay, 2022, Cell reports.

Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.

H. Thomas, T. Kay, A. Lew, 2012, The review of diabetic studies : RDS.

Diabetic mice Regulatory T Cell Function in Nonobese TNF Receptor 1 Deficiency Increases

H. Thomas, T. Kay, H. Bluethmann, 2011 .

Islet Pathology in Type 1 Effector-Memory T Cells Develop in Islets

Thomas, A. Skowera, M. Peakman, 2013 .

Combination immune checkpoint blockade as an effective therapy for mesothelioma

I. Dick, A. Nowak, B. Robinson, 2018, Oncoimmunology.

Functional cytotoxic T lymphocytes against IGRP206‐214 predict diabetes in the non‐obese diabetic mouse

H. Thomas, T. Kay, A. Lew, 2014, Immunology and cell biology.

Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor

L. Boon, H. Thomas, T. Kay, 2022, Clinical & translational immunology.

Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes

H. Thomas, T. Kay, Ranjeny Thomas, 2013, Annals of the New York Academy of Sciences.

Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice

A. Strasser, L. O'Reilly, H. Thomas, 2019, Cell death discovery.

Immunotherapy for Lung Malignancies: From Gene Sequencing to Novel Therapies

R. Holt, J. Creaney, B. Robinson, 2017, Chest.

Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

L. Boon, J. Creaney, I. Dick, 2019, Oncoimmunology.

Reprogramming the anti-tumor immune response via CRISPR genetic and epigenetic editing

P. Blancafort, S. Gaudieri, A. Nowak, 2021, Molecular therapy. Methods & clinical development.

Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies

R. Bradley, E. Newell, J. Creaney, 2021, Proceedings of the National Academy of Sciences.

Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy

R. Holt, L. Boon, A. Chopra, 2020, Frontiers in Immunology.

Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials.

T. Kay, J. Chee, C. Selck, 2016, Journal of autoimmunity.

Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation

M. Cowley, S. Grey, H. Thomas, 2012, Cell transplantation.

Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants*

Shixia Wang, Shan Lu, E. Lien, 2015, The Journal of Biological Chemistry.

Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor

V. Greiff, I. Snapkov, Å. Helland, 2021, Molecular oncology.

CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy.

T. Lassmann, A. Chopra, A. Nowak, 2022, Cell reports.

Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

J. Creaney, C. Saunders, A. Nowak, 2021, Cancer Immunology, Immunotherapy.

Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors

J. Creaney, A. Chopra, A. Nowak, 2018, BMC Research Notes.

Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice

H. Thomas, T. Kay, J. Chee, 2021, Frontiers in Immunology.

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon–Dependent Pathway

J. Trapani, P. Bird, Z. Mollah, 2017, Diabetes.

Unsuccessful checkpoint blockade and vaccination therapy despite expansion of tumor neoantigen-specific CD8 T cells in the Lewis Lung Carcinoma (LLC) model

Y. Simoni, B. Robinson, J. Chee, 2020, The Journal of Immunology.