Matthew A. Davis

发表

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.

John T. Melchior, Richard G. Lee, B. Cravatt, 2013, Cell reports.

ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation[S]

J. Sawyer, L. Rudel, Matthew A. Davis, 2012, Journal of Lipid Research.

Intestinal cholesterol absorption is substantially reduced in mice deficient in both ABCA1 and ACAT2 Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500232-JLR200

J. Sawyer, L. Rudel, R. Temel, 2005, Journal of Lipid Research.

Cholesterol-regulated Translocation of NPC1L1 to the Cell Surface Facilitates Free Cholesterol Uptake*

M. Willingham, J. M. Brown, Pingsheng Liu, 2006, Journal of Biological Chemistry.

Biomarkers of senescence in non-human primate adipose depots relate to aging

Matthew A. Davis, K. Kavanagh, R. Vemuri, 2020, GeroScience.

Estrogen Decreases Atherosclerosis in Part by Reducing Hepatic Acyl-CoA:Cholesterol Acyltransferase 2 (ACAT2) in Monkeys

J. D. Wagner, M. Adams, L. Rudel, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Increased expression of LXRα, ABCG5, ABCG8, and SR-BI in the liver from normolipidemic, nonobese Chinese gallstone patients Published, JLR Papers in Press, November 15, 2007.

Hai Hu, Matt Davis, L. Rudel, 2008, Journal of Lipid Research.

ACAT Inhibition Reduces the Progression of Preexisting, Advanced Atherosclerotic Mouse Lesions Without Plaque or Systemic Toxicity

Christine M. Miller, E. Fisher, J. Rong, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Primates Highly Responsive to Dietary Cholesterol Up-regulate Hepatic ACAT2, and Less Responsive Primates Do Not*

J. Sawyer, L. Rudel, R. Shah, 2002, The Journal of Biological Chemistry.

Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence

J. Cline, D. Caudell, Matthew A. Davis, 2022, GeroScience.

CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

Richard G. Lee, H. Brown, P. Ivanova, 2012, Diabetes.

Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A*

S. Ōmura, Matt Davis, L. Rudel, 2008, Journal of Biological Chemistry.

Supplemental Information /-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin Secretion

M. Prentki, J. M. Brown, J. Iglesias, 2014 .

Early time‐restricted feeding improves high‐density lipoprotein amount and function in nonhuman primates, without effects on body composition

J. Parks, M. Jorgensen, Matthew A. Davis, 2022, Obesity.

Cholesterol Esters (CE) Derived From Hepatic Sterol O-Acyltransferase 2 (SOAT2) Are Associated With More Atherosclerosis Than CE From Intestinal SOAT2

J. M. Brown, J. Sawyer, L. Rudel, 2014, Circulation research.

Control of ACAT2 liver expression by HNF1 Published, JLR Papers in Press, June 16, 2005. DOI 10.1194/jlr.M400450-JLR200

M. Eriksson, L. Rudel, P. Parini, 2005, Journal of Lipid Research.

An ACACB Variant Implicated in Diabetic Nephropathy Associates with Body Mass Index and Gene Expression in Obese Subjects

M. Stumvoll, R. Hanson, S. Kobes, 2013, PloS one.

Control of ACAT2 liver expression by HNF1

M. Eriksson, L. Rudel, P. Parini, 2005 .

Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness.

Hiroshi Tomoda, Satoshi Omura, S. Ōmura, 2004, Journal of lipid research.

ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver

Mats Eriksson, Hiroshi Tomoda, Satoshi Omura, 2004, Circulation.

Identification of a Form of Acyl-CoA:Cholesterol Acyltransferase Specific to Liver and Intestine in Nonhuman Primates*

G. S. Shelness, L. Rudel, R A Anderson, 1998, The Journal of Biological Chemistry.

Identification of putative active site residues of ACAT enzymes** This work was supported by National Institutes of Health Grant P01-HL-49373 to L.L.R. Published, JLR Papers in Press, May 13, 2008.

L. Rudel, Akash Das, Matthew A. Davis, 2008, Journal of Lipid Research.

EARLY TIME RESTRICTED FEEDING IMPROVES HIGH DENSITY LIPOPROTEIN FUNCTION IN GERIATRIC MONKEYS

J. Parks, Matthew A. Davis, K. Kavanagh, 2019, Innovation in Aging.

Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation[S]

J. Sawyer, L. Rudel, Matthew A. Davis, 2012, Journal of Lipid Research.

Matthew A. Davis, K. Kavanagh, R. Vemuri, 2020, bioRxiv.

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice

J. M. Brown, J. Sawyer, L. Rudel, 2013, Journal of Lipid Research.

α/β-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion.

M. Prentki, J. M. Brown, J. Iglesias, 2014, Cell metabolism.

The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis

Richard G. Lee, J. M. Brown, M. Graham, 2017, Journal of Lipid Research.

New Pyripyropene A Derivatives, Highly SOAT2-Selective Inhibitors, Improve Hypercholesterolemia and Atherosclerosis in Atherogenic Mouse Models

S. Ishibashi, L. Rudel, H. Tomoda, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Inhibition of Stearoyl-Coenzyme A Desaturase 1 Dissociates Insulin Resistance and Obesity From Atherosclerosis

Heather M. Alger, J. M. Brown, Soonkyu Chung, 2008, Circulation.

Combined Therapy of Dietary Fish Oil and Stearoyl-CoA Desaturase 1 Inhibition Prevents the Metabolic Syndrome and Atherosclerosis

J. Madenspacher, M. Fessler, Heather M. Alger, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Targeted Depletion of Hepatic ACAT2-driven Cholesterol Esterification Reveals a Non-biliary Route for Fecal Neutral Sterol Loss*

Thomas L. Smith, Mark J Graham, Richard G. Lee, 2008, Journal of Biological Chemistry.

Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion

Richard G. Lee, J. M. Brown, M. Graham, 2014, PloS one.

1-3-2014 Reduction of VLDL Secretion Decreases Cholesterol Excretion in Niemann-Pick C 1-Like 1 Hepatic Transgenic Mice

Richard G. Lee, J. M. Brown, M. Graham, 2017 .

Reduction of VLDL Secretion Decreases Cholesterol Excretion in Niemann-Pick C1-Like 1 Hepatic Transgenic Mice

Richard G. Lee, J. M. Brown, M. Graham, 2014, PloS one.

Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood[S]

Robert V Farese, J. M. Brown, J. Sawyer, 2012, Journal of Lipid Research.

Whole Body Irradiation Induces Diabetes and Adipose Insulin Resistance in Non-human Primates.

D. Wasserman, J. Cline, Matthew A. Davis, 2019, International journal of radiation oncology, biology, physics.

Inhibition of Stearoyl-CoA Desaturase 1 (SCD1) DissociatesInsulin Resistance and Obesity From Atherosclerosis

Heather M. Alger, J. M. Brown, Soonkyu Chung, 2016 .

Tissue-speciﬁ c knockouts of ACAT2 reveal that intestinal depletion is sufﬁ cient to prevent diet-induced cholesterol accumulation in the liver and blood

Robert V Farese, J. M. Brown, J. Sawyer, 2020 .