Yingxiao Shi

发表

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9orf72 dipeptide repeat protein toxicity

Nicholas J Kramer, Aaron D Gitler, Marc Tessier-Lavigne, 2018, Nature Genetics.

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death

N. Shneider, U. Pandey, Shaoyu Lin, 2014, Neuron.

RPS 25 is required for efficient RAN translation of C 9 orf 72 and other 3 neurodegenerative disease-associated nucleotide repeats 4 5

L. Petrucelli, L. Partridge, J. Puglisi, 2019 .

Notch inhibition allows oncogene independent generation of iPS cells

Ava C. Carter, K. Eggan, J. Bradner, 2014, Nature chemical biology.

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Michael J. Cowan, L. H. van den Berg, T. G. Belgard, 2018, Nature Medicine.

Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma

D. Schadendorf, A. Giobbie-Hurder, E. V. Van Allen, 2022, bioRxiv.

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

L. Petrucelli, L. Partridge, J. Puglisi, 2019, Nature Neuroscience.

Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming.

R. Chow, B. Zlokovic, Kassandra Kisler, 2019, Cell stem cell.

Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons.

B. Zlokovic, Yaoming Wang, Shaoyu Lin, 2019, JCI insight.

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

Daniela C. Zarnescu, D. Dickman, D. Zarnescu, 2023, Cell.

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

Gregor Bieri, A. Gitler, M. Tessier-Lavigne, 2018, Nature Genetics.

Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons

A. Gnirke, K. Eggan, E. Kiskinis, 2018, Development.

The C9ORF72 repeat expansion alters neurodevelopment

R. Jacobs, Nomongo Dorjsuren, J. Ichida, 2023, Cell reports.

Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons.

B. Zlokovic, Yaoming Wang, Shaoyu Lin, 2019, JCI insight.