G. Friestad

发表

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Cyanotetraene Construction, Asymmetric Synthesis of the C(26−37) Oxazole, Fragment Assembly, and Final Elaboration

B. Salvatore, K. Hull, E. Bertounesque, 1999 .

A new approach to the pancratistatin C-ring from d-glucose: Ferrier rearrangement, pseudoinversion and Pd-catalyzed cyclizations

B. Branchaud, G. Friestad, 1997 .

Addition of carbon-centered radicals to imines and related compounds

G. Friestad, 2001 .

Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Enantioselective Preparation of γ-Sulfonyl-α-silyloxyaldehydes and Iterative Julia-Kocienski Coupling.

G. Friestad, Gopeekrishnan Sreenilayam, Ryan M. Friedrich, 2018, The Journal of organic chemistry.

Preparation of enol ester epoxides and their ring-opening to α-silyloxyaldehydes

G. Friestad, Gopeekrishnan Sreenilayam, Joseph C. Cannistra, 2012 .

Stereoselective Access to Tubuphenylalanine and Tubuvaline: Improved Mn-Mediated Radical Additions and Assembly of A Tubulysin Tetrapeptide Analog

Jean-Charles Marié, G. Friestad, Lei Yao, 2016, The Journal of Antibiotics.

Synthesis of Chiral Amines by C–C Bond Formation with Photoredox Catalysis

G. Friestad, Stephen T. J. Cullen, 2021, Synthesis.

Stereoselective Mn-mediated coupling of functionalized iodides and hydrazones: a synthetic entry to the tubulysin gamma-amino acids.

Jean-Charles Marié, G. Friestad, A. M. Deveau, 2004, Organic letters.

Diastereocontrol in Radical Addition to β-Benzyloxy Hydrazones: Revised Approach to Tubuvaline and Synthesis of O-Benzyltubulysin V Benzyl Ester

G. Friestad, Koushik Banerjee, Man-Lin Li, 2021, The Journal of organic chemistry.

Recent advances in the synthesis of tubulysins.

G. Friestad, Xu Xiangming, Yao Lei, 2013, Mini reviews in medicinal chemistry.

Enhanced reactivity in radical cyclizations of hydrazones using the silicon-tethered 1-bromovinyl group

G. Friestad, A. Mathies, T. Jiang, 2007 .

Bis(ethoxythiocarbonyl)sulfide

G. Friestad, T. Jiang, 2006 .

Radical additions to chiral hydrazones: stereoselectivity and functional group compatibility.

G. Friestad, 2012, Topics in current chemistry.

Aldehyde-selective Wacker oxidation in a thiyl-mediated vinyl group transfer route to daunosamine.

G. Friestad, A. Mathies, T. Jiang, 2007, Organic letters.

CONVENIENT WACKER OXIDATIONS WITH SUBSTOICHIOMETRIC CUPRIC ACETATE

Y. Cho, Amos B. Smith, G. Friestad, 1998 .

Intermolecular alkyl radical addition to chiral N-acylhydrazones mediated by manganese carbonyl.

G. Friestad, J. Qin, 2001, Journal of the American Chemical Society.

Enantioselective radical addition to N-acyl hydrazones mediated by chiral Lewis acids.

G. Friestad, Yuehai Shen, E. Ruggles, 2003, Angewandte Chemie.

Addition of carbon-centered radicals to imines and related compounds

G. Friestad, 2001 .

Stereocontrol in hydride addition to ketone-derived chiral N-acylhydrazones

G. Friestad, J. Qin, 2003 .

Asymmetric Allylsilane Additions to EnantiopureN-Acylhydrazones with Dual Activation by Fluoride and In(OTf)3

G. Friestad, H. Ding, 2001 .

Alkyl Radical Addition to Aliphatic and Aromatic N-Acylhydrazones Using an Organic Photoredox Catalyst.

G. Friestad, Stephen T. J. Cullen, 2019, Organic letters.

Recent developments in asymmetric catalytic addition to CN bonds

G. Friestad, A. Mathies, 2007 .

STRECKER REACTIONS OF CHIRAL N-ACYLHYDRAZONES

G. Friestad, H. Ding, 2006 .

Inspirations from tetrafibricin and related polyketides: new methods and strategies for 1,5-polyol synthesis.

Ryan M Friedrich, Gregory K Friestad, G. Friestad, 2020, Natural product reports.

Asymmetric Allylsilane Additions to Enantiopure N-Acylhydrazones with Dual Activation by Fluoride and In(OTf)(3) We thank the National Science Foundation (Vermont EPSCoR) and the University of Vermont for generous support.

G. Friestad, H. Ding, 2001, Angewandte Chemie.

Chiral N‐Acylhydrazones: Versatile Imino Acceptors for Asymmetric Amine Synthesis

G. Friestad, 2005 .

Trifluoroacetyl-activated nitrogen-nitrogen bond cleavage of hydrazines by samarium(II) iodide.

Gregory K Friestad, Hui Ding, G. Friestad, 2004, Organic letters.

Intramolecular Pd-catalyzed aryl-enone conjugate additions. Control of reductive vs non-reductive cyclization

B. Branchaud, G. Friestad, 1995 .

Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Preparation and Coupling of C15-C25 and C26-C40 Fragments of Tetrafibricin.

G. Friestad, Ryan M. Friedrich, Zican Shen, 2018, The Journal of organic chemistry.

Access to an anti,syn‐1,5,7‐Triol by Configuration‐Encoded 1,5‐Polyol Synthesis: The C15–C25 Fragment of Tetrafibricin

G. Friestad, Ryan M. Friedrich, 2017 .

Versatile configuration-encoded strategy for rapid synthesis of 1,5-polyol stereoisomers.

G. Friestad, Gopeekrishnan Sreenilayam, 2010, Organic letters.

TOTAL SYNTHESIS OF (+)-CALYCULIN A AND (-)-CALYCULIN B : ASYMMETRIC SYNTHESIS OF THE C(9-25) SPIROKETAL DIPROPIONATE SUBUNIT

B. Salvatore, K. Hull, E. Bertounesque, 1999 .

Effects of alpha-Alkoxy Substitution and Conformational Constraints on 6-exo Radical Cyclizations of Hydrazones via Reversible Thiyl and Stannyl Additions.

G. Friestad, A. Mathies, 2007, Tetrahedron.

Intermolecular nonreductive alkylation of enamides via radical-polar crossover.

G. Friestad, Yaoping Wu, 2009, Organic letters.

Quinine synthesis studies: a radical-ionic annulation via Mn-mediated addition to chiral N-acylhydrazones.

G. Friestad, Chandra Sekhar Korapala, J. Qin, 2007, Organic letters.

Asymmetric Methods for Radical Addition to Imino Compounds

G. Friestad, 2010 .

A Tamao–Fleming oxidation route to dipeptides bearing N,O-acetal functionality

G. Friestad, S. Ibrahim, Koushik Banerjee, 2017 .

Organomanganese‐Mediated Radical Reactions

G. Friestad, 2010 .

Dual activation in asymmetric allylsilane addition to chiral N-acylhydrazones: method development, mechanistic studies, and elaboration of homoallylic amine adducts.

G. Friestad, H. Ding, Chandra Sekhar Korapala, 2006, The Journal of organic chemistry.

Asymmetric Addition of Allylic Nucleophiles to Imino Compounds

G. Friestad, H. Ding, 2005 .

Scope of stereoselective Mn-mediated radical addition to chiral hydrazones and application in a formal synthesis of quinine.

J. Baltrusaitis, G. Friestad, Chandra Sekhar Korapala, 2012, The Journal of organic chemistry.

Intermolecular radical addition to N-acylhydrazones as a stereocontrol strategy for alkaloid synthesis: formal synthesis of quinine.

G. Friestad, Chandra Sekhar Korapala, J. Qin, 2011, Organic & biomolecular chemistry.

Mn-mediated coupling of alkyl iodides and ketimines: a radical addition route to alpha,alpha-disubstituted alpha-aminoesters.

G. Friestad, A. Ji, 2008, Organic letters.

Stereocontrol in radical Mannich equivalents for aminosugar synthesis: haloacetal and 2-(phenylthio)vinyl tethered radical additions to α-hydroxyhydrazones

Gina M. Fioroni, G. Friestad, T. Jiang, 2008 .

Control of asymmetry in the radical addition approach to chiral amine synthesis.

G. Friestad, 2014, Topics in current chemistry.

Tandem thiyl radical addition and cyclization of chiral hydrazones using a silicon-tethered alkyne

Gina M. Fioroni, G. Friestad, T. Jiang, 2003 .

Enantioselective Radical Addition to N‐Acyl Hydrazones Mediated by Chiral Lewis Acids.

G. Friestad, Yuehai Shen, E. Ruggles, 2004 .

Mn-Mediated Radical-Ionic Annulations of Chiral N-Acylhydrazones.

G. Friestad, Kara A. Slater, 2015, The Journal of organic chemistry.

Haloacetal Radical Cyclizations of α- and β-Hydroxyhydrazones

Gina M. Fioroni, G. Friestad, 2005 .

Highly Stereoselective Intermolecular Radical Addition to Aldehyde Hydrazones from a Chiral 3-Amino-2-oxazolidinone.

G. Friestad, J. Qin, 2000 .

SILICON-CONTAINING HETEROCYCLES IN STEREOCONTROLLED RADICAL ADDITIONS TO CHIRAL HYDRAZONES

G. Friestad, A. Mathies, T. Jiang, 2004 .

A Silicon Tether Approach for Diastereocontrol in Radical Addition to Chiral Hydrazones

G. Friestad, 1999 .

A silicon tether approach for addition of functionalized radicals to chiral alpha-hydroxyhydrazones: diastereoselective additions of hydroxymethyl and vinyl synthons.

G. Friestad, S. Massari, 2004, The Journal of organic chemistry.

Mn-mediated coupling of alkyl iodides and chiral N-acylhydrazones: optimization, scope, and evidence for a radical mechanism.

Jean-Charles Marié, G. Friestad, J. Qin, 2006, The Journal of organic chemistry.

Stereocontrol in Hydride Addition to Ketone‐Derived Chiral N‐Acylhydrazones.

G. Friestad, J. Qin, 2003 .

Comparison of electrophilic amination reagents for N-amination of 2-oxazolidinones and application to synthesis of chiral hydrazones.

G. Friestad, Yuehai Shen, 2002, The Journal of organic chemistry.

Trans-2,5-disubstituted tetrahydrofurans via addition of carbon nucleophiles to the strained bicyclic acetal 2,7-dioxabicyclo[2.2.1]heptane.

G. Friestad, H. Lee, 2009, Organic letters.

Radicals in Synthesis III

G. Friestad, A. Gansäuer, M. Heinrich, 2006 .

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B

B. Salvatore, K. Hull, Amos B. Smith, 1998 .

Total Synthesis of (+)‐Calyculin A and (‐)‐Calyculin B: Asymmetric Synthesis of the C(9—25) Spiroketal Dipropionate Subunit (I).

B. Salvatore, K. Hull, E. Bertounesque, 2000 .

1,5-Polyols: Challenging motifs for configurational assignment and synthesis

G. Friestad, Gopeekrishnan Sreenilayam, 2011 .

Chiral action at a distance: remote substituent effects on the optical activity of calyculins A and B.

P. Wipf, D. Beratan, R. Kondru, 2000, Organic letters.

An approach to (+)-pancratistatin from D-glucose: A conformational lock solves a stereochemical problem

B. Branchaud, G. Friestad, Heather S. Blanchette, 1999 .

N‐Acylated Benzylic Amines via Photocatalytic Hydroarylation of Enamides

G. Friestad, Jalen L. Dickson, 2023, ChemistrySelect.