Richard Lu

发表

Genetic Analyses of DNA-Binding Mutants in the Catalytic Core Domain of Human Immunodeficiency Virus Type 1 Integrase

A. Engelman, A. Limón, Richard Lu, 2005, Journal of Virology.

Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation.

J. Bibb, K. Herrup, Robert H Miller, 2013, Developmental biology.

Bacterial Exploitation of Host Cell Signaling

M. Goldberg, Richard Lu, 2010, Science Translational Medicine.

Lys-34, Dispensable for Integrase Catalysis, Is Required for Preintegration Complex Function and Human Immunodeficiency Virus Type 1 Replication

A. Engelman, P. Cherepanov, N. Vandegraaff, 2005, Journal of Virology.

Genetic Analyses of Conserved Residues in the Carboxyl-Terminal Domain of Human Immunodeficiency Virus Type 1 Integrase

A. Engelman, Richard Lu, H. Ghory, 2005, Journal of Virology.

Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness.

A. Engelman, P. Cherepanov, Shaila Rahman, 2007, Virology.

Recurrent Glioblastoma is Associated with a Closed DNA Conformation

K. Roskin, D. Plas, M. Lamba, 2021 .

Fc-engineered antibodies leverage neutrophils to drive control of Mycobacterium tuberculosis

Bryan D. Bryson, A. Casadevall, S. Fortune, 2022, bioRxiv.

Human Immunodeficiency Virus Type 1 Replication in the Absence of Integrase-Mediated DNA Recombination: Definition of Permissive and Nonpermissive T-Cell Lines

A. Engelman, N. Nakajima, Richard Lu, 2001, Journal of Virology.

A Fc-Engineering Approach to Define Functional Humoral Correlates of Immunity Against Ebola Virus

Y. Kawaoka, A. Takada, P. Halfmann, 2020, SSRN Electronic Journal.

Characterization of a Replication-Competent, Integrase-Defective Human Immunodeficiency Virus (HIV)/Simian Virus 40 Chimera as a Powerful Tool for the Discovery and Validation of HIV Integrase Inhibitors

A. Engelman, E. De Clercq, D. Daelemans, 2007, Journal of Virology.

In vivo biotinylation and capture of HIV-1 matrix and integrase proteins.

A. Engelman, Cameron J. Schweitzer, Richard Lu, 2009, Journal of virological methods.

Class II Integrase Mutants with Changes in Putative Nuclear Localization Signals Are Primarily Blocked at a Postnuclear Entry Step of Human Immunodeficiency Virus Type 1 Replication

A. Engelman, P. Silver, P. Cherepanov, 2004, Journal of Virology.

Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube

D. Rowitch, T. Sun, C. Stiles, 2001, Current Biology.

Nuclear Localization of Human Immunodeficiency Virus Type 1 Preintegration Complexes (PICs): V165A and R166A Are Pleiotropic Integrase Mutants Primarily Defective for Integration, Not PIC Nuclear Import

A. Engelman, P. Silver, A. Limón, 2002, Journal of Virology.

Simian Virus 40-Based Replication of Catalytically Inactive Human Immunodeficiency Virus Type 1 Integrase Mutants in Nonpermissive T Cells and Monocyte-Derived Macrophages

A. Engelman, J. Sodroski, W. Hofmann, 2004, Journal of Virology.

Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control

M. Carrington, B. Walker, Y. Qi, 2013, Nature Medicine.

Wild-Type Levels of Nuclear Localization and Human Immunodeficiency Virus Type 1 Replication in the Absence of the Central DNA Flap

A. Engelman, A. Limón, N. Nakajima, 2002, Journal of Virology.

Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome

D. Heckerman, E. Rosenberg, H. Jessen, 2014, Journal of Virology.

Induction of Gag-Specific CD4 T Cell Responses during Acute HIV Infection Is Associated with Improved Viral Control

E. Rosenberg, H. Jessen, G. Alter, 2014, Journal of Virology.

Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

D. Lauffenburger, J. Weiner, Jishnu Das, 2020, Science Translational Medicine.

Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia

M. Robb, G. Alter, N. Michael, 2015, Journal of Virology.

The challenge of regenerative therapies for the optic nerve in glaucoma

D. Zack, A. Huberman, J. Crowston, 2017, Experimental eye research.

Chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.

Yi Zheng, Z. Tu, Chuntao Zhao, 2021, Blood.

Inhibition of adrenergic β1-AR/Gαs signaling promotes cardiomyocyte proliferation through activation of RhoA-YAP axis

Richard Lu, Mei Xin, Masahide Sakabe, 2021, bioRxiv.

HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma

K. Roskin, D. Plas, H. Kornblum, 2023, Scientific reports.

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination

S. Friedman, E. Zaslavsky, G. Nudelman, 2016, PLoS biology.