J. Cookson

发表

Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism

R. Gartenhaus, A. Burger, F. Dai, 2007, British Journal of Cancer.

Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor RHPS 4 in vitro : activity in human tumor cells correlates with telomere length and can be enhanced , or antagonized , with cytotoxic agents

C. Laughton, R. Heald, A. Burger, 2005 .

Inhibitory actions of loperamide on absorptive processes in rat small intestine.

J. Cookson, P. Hardcastle, J. Hardcastle, 1986, Gut.

Castle: Ideologies of Exclusion in American Domestic Space

J. Cookson, 2016 .

Antitumor polycyclic acridines. 8.(1) Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts.

Charles A Laughton, Chetna Modi, C. Laughton, 2002, Journal of medicinal chemistry.

The levels of telomere-binding proteins in human tumours and therapeutic implications.

C. Laughton, J. Cookson, 2009, European journal of cancer.

Mechanisms of neuromuscular block

J. Cookson, W. Paton, 1969, Anaesthesia.

Pharmacodynamics of the G-Quadruplex-Stabilizing Telomerase Inhibitor 3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in Vitro: Activity in Human Tumor Cells Correlates with Telomere Length and Can Be Enhanced, or Antagonized, with Cytotoxic Agents

Charles A Laughton, C. Laughton, R. Heald, 2005, Molecular Pharmacology.

Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.

W. Wilson, J. Mergny, C. Laughton, 2008, Journal of medicinal chemistry.

Elucidation of thioredoxin as a molecular target for antitumor quinols.

A. Monks, C. Laughton, M. Stevens, 2005, Cancer research.

Antitumor polycyclic acridines. 17. Synthesis and pharmaceutical profiles of pentacyclic acridinium salts designed to destabilize telomeric integrity.

M. Stevens, R. Heald, J. Cookson, 2005, Journal of medicinal chemistry.