C. Trigili

发表

Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.

V. Tumiatti, A. Milelli, A. Minarini, 2012, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of α‐Tubulin‐Binding Pironetin Analogues with Enhanced Lipophilicity

I. Barasoain, M. Carda, E. Falomir, 2013 .

Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivatives.

M. Redondo-Horcajo, I. Barasoain, M. Carda, 2013, Current medicinal chemistry.

Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules.

I. Barasoain, J. Díaz, M. Carda, 2011, European journal of medicinal chemistry.

Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells

M. Steinmetz, A. Nogales, F. Gago, 2016, ACS omega.

Highly Stereoselective Total Synthesis of (+)‐9‐epi‐Dictyostatin and (–)‐12,13‐Bis‐epi‐dictyostatin

I. Barasoain, J. Díaz, C. Trigili, 2011 .

Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.

K. Altmann, I. Barasoain, J. Díaz, 2012, Chemistry & biology.

Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J

I. Barasoain, M. Barbazanges, C. Meyer, 2011, Chembiochem : a European journal of chemical biology.

Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.

Maurizio Botta, Mattia Mori, Giorgio Maccari, 2010, Chemistry & biology.

Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.

I. Barasoain, C. Trigili, J. Andreu, 2012, Journal of medicinal chemistry.

Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.

A. Nogales, I. Barasoain, I. Ojima, 2014, Bioorganic & medicinal chemistry.

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

I. Paterson, C. Trigili, Á. Canales, 2011, ACS chemical biology.

Molecular Recognition of Peloruside A by Microtubules. The C24 Primary Alcohol is Essential for Biological Activity

I. Barasoain, J. Díaz, P. Northcote, 2010, Chembiochem : a European journal of chemical biology.

Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.

I. Barasoain, Xi Xiao, Y. Li, 2011, Bioorganic & medicinal chemistry letters.

Molecular Recognition of Peloruside A by Microtubules. The C24 Primary Alcohol is Essential for Biological Activity

I. Barasoain, J. Díaz, P. Northcote, 2010, Chembiochem : a European journal of chemical biology.

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

I. Paterson, C. Trigili, Á. Canales, 2011, ACS chemical biology.