C. Gravier-Pelletier

发表

5'-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling.

B. Joris, D. Mengin-Lecreulx, N. Pietrancosta, 2015, Organic & biomolecular chemistry.

Effect of uridine protecting groups on the diastereoselectivity of uridine-derived aldehyde 5’-alkynylation

L. Le Corre, Mickaël J. Fer, Sandrine Calvet-Vitale, 2017, Beilstein journal of organic chemistry.

Efficient synthesis of a bacterial translocase MraY inhibitor

A. Bouhss, C. Gravier-Pelletier, A. Clouet, 2008 .

Bacterial transferase MraY inhibitors: synthesis and biological evaluation.

Delphine Lecerclé, A. Bouhss, C. Gravier-Pelletier, 2010, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of a diazepanone-based library of liposidomycins analogs as MraY inhibitors.

Janez Mravljak, A. Bouhss, C. Gravier-Pelletier, 2011, European journal of medicinal chemistry.

Toward analogues of MraY natural inhibitors: synthesis of 5'-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition.

A. Bouhss, Mickaël J. Fer, Sandrine Calvet-Vitale, 2013, The Journal of organic chemistry.

A diastereoselective synthesis of 5'-substituted-uridine derivatives.

T. Prangé, Mickaël J. Fer, Sandrine Calvet-Vitale, 2014, The Journal of organic chemistry.

Chemical investigations in the synthesis of O-serinyl aminoribosides

C. Gravier-Pelletier, Y. Merrer, Maryon Ginisty, 2006 .

Synthesis and glycosidase inhibitory activity of new penta-substituted C8-glycomimetics

P. Vogel, C. Gravier-Pelletier, Y. Merrer, 2005 .

Mono, di and tri-mannopyranosyl phosphates as mannose-1-phosphate prodrugs for potential CDG-Ia therapy.

C. Gravier-Pelletier, Y. Le Merrer, T. Dupré, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of C8-glycomimetics as potential glycosidases inhibitors

C. Gravier-Pelletier, Y. Merrer, Olivia Andriuzzi, 2004 .

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

C. Dowson, D. Roper, A. Bouhss, 2019, Molecules.

New azadisaccharide analogs as potential antidiabetics

C. Gravier-Pelletier, Y. Merrer, William Maton, 2002 .

Synthetic studies towards diazepanone scaffolds

G. Bertho, Janez Mravljak, C. Gravier-Pelletier, 2009 .

Lipoxins A4 and B4 Total Synthesis Including Deprotection Studies

J. Dumas, C. Gravier-Pelletier, Y. Merrer, 1992 .

Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation

Susan J Paik, C. Gravier-Pelletier, S. Moore, 2020, Molecules.

Synthesis and biological evaluation of chemical tools for the study of Dolichol Linked Oligosaccharide Diphosphatase (DLODP).

A. Bouhss, C. Gravier-Pelletier, I. Chantret, 2017, European journal of medicinal chemistry.

Chiral α-hydroxy- and α,β-dihydroxy- aldehydes from D-isoascorbic and L-ascorbic acids. Useful precursors for the synthesis of fatty acid metabolites.

J. Dumas, C. Gravier-Pelletier, Y. Merrer, 1990 .

Nucleophilic Opening of an Epoxide by a Masked Glycine Anion Equivalent: A Route to C-Glycosyl Amino Acids

Janez Mravljak, R. Frlan, C. Gravier-Pelletier, 2016, Synlett.

Synthesis of 1-C-linked diphosphate analogues of UDP-N-Ac-glucosamine and UDP-N-Ac-muramic acid

S. Gobec, S. Pečar, A. Babič, 2008 .

Brefeldin A promotes the appearance of oligosaccharyl phosphates derived from Glc3Man9GlcNAc2-PP-dolichol within the endomembrane system of HepG2 cells

C. Gravier-Pelletier, I. Chantret, S. Moore, 2016, Journal of Lipid Research.

Demonstration of an oligosaccharide-diphosphodolichol diphosphatase activity whose subcellular localization is different than those of dolichyl-phosphate-dependent enzymes of the dolichol cycle

C. Gravier-Pelletier, I. Chantret, N. Auberger, 2016, Journal of Lipid Research.

Synthesis of bis-(2,3,4,6-tetra-O-acetyl-α-d-mannopyranosyl)-l-serinyl phosphate, as a prodrug of mannose-1-phosphate

C. Gravier-Pelletier, Y. Merrer, A. Khaled, 2007 .

Synthesis of polyhydroxylated piperidines and evaluation as glycosidase inhibitors.

Marie-Christine Lallemand, F. Tillequin, C. Gravier-Pelletier, 2004, Bioorganic & medicinal chemistry.

A versatile scaffold for a library of liposidomycins analogues: a crucial and potent glycosylation step

C. Gravier-Pelletier, Y. Merrer, Maryon Ginisty, 2004 .

Synthesis and biological evaluation of potential new inhibitors of the bacterial transferase MraY with a β-ketophosphonate structure.

A. Bouhss, R. Frlan, C. Gravier-Pelletier, 2011, Organic & biomolecular chemistry.

Synthesis and glycosidase inhibitory activity of new hexa-substituted C8-glycomimetics

T. Prangé, G. Bertho, C. Gravier-Pelletier, 2005, Beilstein journal of organic chemistry.

A CONCISE ROUTE TO CARBASUGARS

C. Gravier-Pelletier, Y. Merrer, William Maton, 1999 .

Regioselective Functionalization of Quinolines through C-H Activation: A Comprehensive Review

C. Gravier-Pelletier, P. Busca, Alessandra Corio, 2021, Molecules.

Microwave-assisted preparation of 4-amino-3-cyano-5-methoxycarbonyl-N-arylpyrazoles as building blocks for the diversity-oriented synthesis of pyrazole-based polycyclic scaffolds.

L. Le Corre, C. Gravier-Pelletier, P. Busca, 2015, Organic & biomolecular chemistry.

Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring

C. Tellier, C. Gravier-Pelletier, Y. Merrer, 2003 .

Liposidomycins − Synthetic Studies Towards the Ribosyldiazepanone Moiety

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 2001 .

Nucleophilic Opening of Epoxide by Guanidine. A Route to Potential Substrates or Inhibitors of NO Synthases.

D. Bourissou, C. Gravier-Pelletier, Y. Merrer, 1996 .

Nucleophilic Opening of Epoxide by Guanidine. A Route to Potential Substrates or Inhibitors of NO Synthases1

D. Bourissou, C. Gravier-Pelletier, Y. Merrer, 1996 .

Synthesis and glycosidase inhibitory activity of enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine

G. Bertho, C. Gravier-Pelletier, Y. Merrer, 2003 .

A Concise Route to Carbasugars.

C. Gravier-Pelletier, Y. Merrer, William Maton, 1999 .

Synthesis of C2-symmetric guanidino-sugars as potent inhibitors of glycosidases.

C. Gravier-Pelletier, Y. Le Merrer, J. Depezay, 2000, Bioorganic & medicinal chemistry.

Recent advances in nanotechnology for eradicating bacterial biofilm

R. Briandet, S. Moya, J. Lomas, 2022, Theranostics.

Total synthesis of leukotriene B4 [(+)-LTB4] and homo-LTB4 from D-mannitol

C. Gravier-Pelletier, Y. Merrer, F. Mestre, 1989 .

Total synthesis of lipoxins A4 and B4 from d-isoascorbic acid

J. Dumas, C. Gravier-Pelletier, Y. Merrer, 1991 .

Total Synthesis of Leukotriene B4 ((+)-LTB4) (Ia) and Homo-LTB4 (Ib) from D-Mannitol.

C. Gravier-Pelletier, Y. Merrer, F. Mestre, 1989 .

Enantiopure hydroxylactones from L-ascorbic and D-isoascorbic acids. Part II. Synthesis of (−)-(5R, 6S)-6-acetoxy-5-hexadecanolide and its diastereomers

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 1995 .

Synthesis of 1,2-Epoxy-3-alkanols via Mitsunobu Reaction on Unprotected Enantiopure Acyclic 1,2,3-Triols

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 1994 .

Synthesis of a β‐Ketophosphonate Bioisostere of UDP‐N‐acetylglucosamine

C. Gravier-Pelletier, Y. Merrer, N. Auberger, 2009 .

Efficient synthesis of polyfunctionalised enantiopure diazepanone scaffolds

G. Bertho, C. Gravier-Pelletier, Y. Merrer, 2007 .

Synthesis of (-)-Muricatacin and (-)-(5R,6S)-6-acetoxy-5-hexadecanolide, the Mosquito oviposition attractant pheromone, from D-isoascorbic acid

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 1994 .

Efficient route to optically pure polyfunctionalized cyclooctanes

C. Gravier-Pelletier, Y. Merrer, Olivia Andriuzzi, 2002 .

ON THE WAY TO LIPOSIDOMYCINS, NEW NUCLEOSIDE ANTIBIOTICS. ACCESS TO THE HOMOCHIRAL DIAZEPANONE CORE

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 1997 .

Destabilization of the human RED–SMU1 splicing complex as a basis for host-directed antiinfluenza strategy

P. Vidalain, Y. Jacob, R. Ruigrok, 2019, Proceedings of the National Academy of Sciences.

Modulators of CFTR. Updates on clinical development and future directions.

I. Sermet-Gaudelus, M. Semeraro, C. Gravier-Pelletier, 2021, European journal of medicinal chemistry.

Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae

E. Breukink, C. Morlot, K. Peters, 2018, Nature Communications.

Bacterial Transferase MraY, a Source of Inspiration towards New Antibiotics.

N. Pietrancosta, A. Bouhss, L. L. Corre, 2019, Current medicinal chemistry.

Systemic bis-phosphinic acid derivative restores chloride transport in Cystic Fibrosis mice

J. Jais, C. Schreiweis, S. Moriceau, 2022, Scientific Reports.

New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation

J. Mornon, I. Sermet-Gaudelus, I. Callebaut, 2021, Scientific Reports.

Efficient access to azadisaccharide analogues

C. Gravier-Pelletier, Y. Merrer, T. Lecourt, 2001 .

New MraYAA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole

B. Joris, R. Auger, A. Amoroso, 2022, Antibiotics.

A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling

B. Joris, A. Bouhss, A. Amoroso, 2022, Molecules.

Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors.

B. Joris, R. Auger, A. Bouhss, 2021, Organic & biomolecular chemistry.

Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor.

V. Calvez, O. Delelis, S. Priet, 2020, RSC medicinal chemistry.

Synthesis of Multifunctionalized 2-Iminothiazolidin-4-ones and Their 2-Arylimino Derivatives

L. Le Corre, C. Garbay, C. Gravier-Pelletier, 2016, Synthesis.

Access to enantiopure ribosyl-diazepanone core of liposidomycins

C. Gravier-Pelletier, Y. Merrer, J. Depezay, 1998 .

Brefeldin A promotes the appearance of oligosaccharyl phosphates derived from Glc3Man9GlcNAc2-PP-dolichol within the endomembrane system of HepG2 cells

C. Gravier-Pelletier, I. Chantret, S. Moore, 2016, Journal of Lipid Research.

Towards New MraY Inhibitors: A Serine Template for Uracil and 5-Amino-5-deoxyribosyl Scaffolding

L. L. Corre, C. Gravier-Pelletier, Y. Merrer, 2007 .

Synthesis and glycosidase inhibitory activity of enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine

G. Bertho, C. Gravier-Pelletier, Y. Merrer, 2003 .