D. Perrone

发表

Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications

D. Perrone, E. Marchesi, Lorenzo Preti, 2021, Molecules.

Biodistribution and Molecular Studies on Orally Administered Nanoparticle-AON Complexes Encapsulated with Alginate Aiming at Inducing Dystrophin Rescue in mdx Mice

M. Falzarano, A. Ferlini, N. Maraldi, 2013, BioMed research international.

Gold-nanoparticle extraction and reversed-electrode-polarity stacking mode combined to enhance capillary electrophoresis sensitivity for conjugated nucleosides and oligonucleotides containing thioether linkers

Alberto Cavazzini, A. Cavazzini, D. Perrone, 2015, Analytical and Bioanalytical Chemistry.

NO Photoreleaser-Deoxyadenosine and -Bile Acid Derivative Bioconjugates as Novel Potential Photochemotherapeutics.

V. Cardile, Aurore Fraix, S. Sortino, 2016, ACS medicinal chemistry letters.

Synthesis and in vitro cytotoxicity of deoxyadenosine–bile acid conjugates linked with 1,2,3-triazole

K. Varani, O. Bortolini, D. Perrone, 2013 .

Porphyrins in 1,3-dipolar cycloaddition reactions with sugar nitrones. Synthesis of glycoconjugated isoxazolidine-fused chlorins and bacteriochlorins

M. Neves, A. Tomé, J. Cavaleiro, 2002 .

Synthesis and Biological Investigation of Bile Acid-Paclitaxel Hybrids

P. Secchiero, E. Rimondi, D. Perrone, 2022, Molecules.

UDP-GlcNAc Analogues as Inhibitors of O-GlcNAc Transferase (OGT): Spectroscopic, Computational, and Biological Studies.

D. V. van Aalten, P. Merino, D. Perrone, 2018, Chemistry.

Antisense-induced messenger depletion corrects a COL6A2 dominant mutation in Ullrich myopathy.

A. Ferlini, E. Pegoraro, P. Bonaldo, 2012, Human gene therapy.

Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy.

S. Campaner, F. Bernardi, M. Pinotti, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Synthesis and Exon-Skipping Properties of a 3′-Ursodeoxycholic Acid-Conjugated Oligonucleotide Targeting DMD Pre-mRNA: Pre-Synthetic versus Post-Synthetic Approach

K. Mamchaoui, D. Perrone, E. Marchesi, 2021, Molecules.

Antisense Oligonucleotides Conjugated with Lipophilic Compounds: Synthesis and In Vitro Evaluation of Exon Skipping in Duchenne Muscular Dystrophy

R. Cortesi, P. Rimessi, D. Perrone, 2022, International journal of molecular sciences.

Isolation of lycopene from crude tomato extract via selective inclusion in deoxycholic acid

A. Medici, D. Perrone, G. Fantin, 2007 .

11. L-Nucleosides

D. Perrone, M. Capobianco, 2013 .

2-Thiazolyl α-Amino Ketones: A New Class of Reactive Intermediates for the Stereocontrolled Synthesis of Unusual Amino Acids

D. Perrone, A. Dondoni, 2010 .

Conjugated Oligonucleotides for Biochemical Applications

D. Perrone, E. Marchesi, M. L. Navacchia, 2017 .

A New and Expedient Diastereoselective Synthesis of α‐(Hydroxyamino)phosphonates and α‐Aminophosphonates by Silyl Triflate Promoted Diethyl Phosphite Addition to Chiral N‐Benzyl Nitrones

V. Bertolasi, D. Perrone, G. Pollini, 2003 .

O-Silyl triflate-promoted addition of diethyl phosphite to chiral aldonitrones. A rapid access to complex α-amino phosphonates and their N-hydroxy derivatives

D. Perrone, G. Pollini, C. D. Risi, 2001 .

Synthesis of Taxol and Taxotere Side Chains by 2-(Trimethylsilyl)thiazole Based Homologation of L-Phenylglycine

D. Perrone, A. Dondoni, Teresa Semola, 1995 .

Fluorous-tag assisted synthesis of bile acid-bisphosphonate conjugates via orthogonal click reactions: an access to potential anti-resorption bone drugs.

O. Bortolini, D. Perrone, E. Marchesi, 2017, Organic & biomolecular chemistry.

Chelation- and Non-chelation-Controlled Addition of 2-(Trimethylsilyl)thiazole to .alpha.-Amino Aldehydes: Stereoselective Synthesis of the .beta.-Amino-.alpha.-hydroxy Aldehyde Intermediate for the Preparation of the Human Immunodeficiency Virus Proteinase Inhibitor Ro 31-8959

P. Merino, D. Perrone, A. Dondoni, 1995 .

Totally chemical synthesis of azasugars via thiazole intermediates. Stereodivergent routes to (-)-nojirimycin, (-)-mannojirimycin and their 3-deoxy derivatives from serine

P. Merino, D. Perrone, A. Dondoni, 1993 .

New entry to pyrrolidine homoazasugars: conversion of d-arabinose into 2,5-anhydro-2,5-imino-d-glucitol via aminohomologation

D. Perrone, A. Dondoni, 1999 .

A convenient synthesis of iminosugar-C-glycosides via organometallic addition to N-benzyl-N-glycosylhydroxylamines

D. Perrone, A. Dondoni, 2003 .

New synthesis of pyrrolidine homoazasugars via aminohomologation of furanoses and their use for the stereoselective synthesis of aza-C-disaccharides.

D. Perrone, A. Dondoni, P. Giovannini, 2002, The Journal of organic chemistry.

Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

D. Perrone, A. Dondoni, M. Sêmola, 1995 .

Synthesis of beta-D-Galactosyl Ceramide Methylene Isostere.

D. Perrone, A. Dondoni, Elisa Turturici, 1999, The Journal of organic chemistry.

TOTAL SYNTHESIS OF (+)-GALACTOSTATIN. AN ILLUSTRATION OF THE UTILITY OF THE THIAZOLE-ALDEHYDE SYNTHESIS

D. Perrone, A. Dondoni, 1995 .

Preparation and characterization of some keto-bile acid azines

O. Bortolini, V. Bertolasi, D. Perrone, 2007, Steroids.

Guest dependent inversion of enantiomeric recognition in dehydrocholic acid host–guest enclathration

O. Bortolini, D. Perrone, G. Fantin, 2007 .

Brain uptake of a Zidovudine prodrug after nasal administration of solid lipid microparticles.

L. Ferraro, S. Beggiato, E. Leo, 2014, Molecular pharmaceutics.

Bile Acid Conjugates with Anticancer Activity: Most Recent Research

D. Perrone, E. Marchesi, M. L. Navacchia, 2020, Molecules.

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells

J. Guh, D. Perrone, E. Marchesi, 2020, Frontiers in Pharmacology.

A New Drug Delivery System Based on Tauroursodeoxycholic Acid and PEDOT.

L. Fadiga, A. Armirotti, F. Ciarpella, 2018, Chemistry.

Synthesis of 1,1‐Dimethylethyl (S)‐4‐Formyl‐2,2‐Dimethyl‐3‐Oxazolidinecarboxylate by Oxidation of the Alcohol

D. Perrone, A. Dondoni, 2003 .

Cross-metathesis of C-allyl iminosugars with alkenyl oxazolidines as a key step in the synthesis of C-iminoglycosyl alpha-amino acids. A route to iminosugar containing C-glycopeptides.

D. Perrone, A. Dondoni, P. Giovannini, 2005, The Journal of organic chemistry.

Stereocontrolled total synthesis of galactostatin from serine

P. Merino, D. Perrone, A. Dondoni, 1991 .

Improved, gram scale synthesis ofN,O,O-triacetyl-erythro- andthreo-C18-sphingosines from serine

D. Perrone, Elisa Turturici, Alessondro Dondoni, 1997 .

Synthesis of N-(tert-Butoxycarbonyl)-N,O-isopropylidene Serinal from Serine Methyl Ester by a Reduction-Oxidation Sequence

D. Perrone, Alessandro Dondini, 1997 .

Improved, Gram Scale Synthesis of N,O,O-Triacetyl-erythro- and threo- C18-Sphingosines from Serine.

D. Perrone, A. Dondoni, Elisa Turturici, 1997 .

Efficacious modification of the procedure for the aldehyde release from 2-substituted thiazoles

A. Marra, D. Perrone, A. Dondoni, 1993 .

Synthesis of C2-symmetric dibenzyldiamino diols by double stereoselective grignard addition to (S,S)-tartraldehyde dinitrone

D. Perrone, A. Dondoni, M. Rinaldi, 1998 .

Labeling deoxyadenosine for the preparation of functional conjugated oligonucleotides.

D. Perrone, E. Marchesi, M. L. Navacchia, 2013, Bioconjugate chemistry.

Zidovudine and ursodeoxycholic acid conjugation: design of a new prodrug potentially able to bypass the active efflux transport systems of the central nervous system.

S. Beggiato, A. Dalpiaz, A. Medici, 2012, Molecular pharmaceutics.

Homologation of L-threonine to α-epimer β-amino-α,γ-dihydroxy aldehydes and acids via stereoselective reduction of 2-thiazolyl amino ketones

P. Merino, D. Perrone, A. Dondoni, 1991 .

Diastereoselective Synthesis of Protected Vicinal Amino Alcohols: (S)‐2‐[(4S)‐N‐tert‐Butoxycarbonyl‐2,2‐Dimethyl‐1,3‐Oxazolidinyl]‐2‐tert‐Butyldimethylsiloxyethanal from a Serine‐Derived Aldehyde

D. Perrone, A. Dondoni, 2003 .

Efficacious Modification of the Procedure for the Aldehyde Release from 2-Substituted Thiazoles.

A. Marra, D. Perrone, A. Dondoni, 1993 .

Rational Design of Nucleoside–Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration

R. Gavioli, D. Perrone, E. Marchesi, 2017, Molecules.

Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse.

Luciano Merlini, Paola Braghetta, Alessandra Ferlini, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

STEREOCONTROLLED SYNTHESIS OF PSEUDO C2-SYMMETRIC 1,3-DIAMINO-2-PROPANOL CORE UNITS OF HIV PROTEASE INHIBITORS

D. Perrone, A. Dondoni, 1997 .

Stereocontrolled Synthesis of Pseudo C2-Symmetric 1,3-Diamino-2- propanol Core Units of HIV Protease Inhibitors.

D. Perrone, A. Dondoni, 1997 .

Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death

P. Pinton, S. Marchi, C. Giorgi, 2016, Molecular biology of the cell.

Regulation of a strong F9 cryptic 5′ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides

F. Bernardi, N. Cavallari, M. Pinotti, 2015, Human molecular genetics.

Oligonucleotides: Current trends and innovative applications in the synthesis, characterization and purification.

Thomas Müller-Späth, Massimo Morbidelli, Martina Catani, 2020, Biotechnology journal.

Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity

J. Guh, D. Perrone, E. Marchesi, 2019, ChemMedChem.

Antisense modulation of both exonic and intronic splicing motifs induces skipping of a DMD pseudo-exon responsible for x-linked dilated cardiomyopathy.

C. Rapezzi, A. Ferlini, A. Medici, 2010, Human gene therapy.

Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells

J. Guh, D. Perrone, E. Marchesi, 2023, Molecules.

7α- and 12α-Hydroxysteroid dehydrogenases from Acinetobacter calcoaceticus lwoffii: a new integrated chemo-enzymatic route to ursodeoxycholic acid

D. Perrone, P. Giovannini, G. Fantin, 2008, Steroids.

Exon skipping‐mediated dystrophin reading frame restoration for small mutations

A. Ferlini, P. Spitali, N. Maraldi, 2009, Human mutation.

Persistent Dystrophin Protein Restoration 90 Days after a Course of Intraperitoneally Administered Naked 2′OMePS AON and ZM2 NP-AON Complexes in mdx Mice

A. Ferlini, P. Braghetta, P. Bonaldo, 2012, Journal of biomedicine & biotechnology.

Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine.

D. Perrone, Anna Fantinati, C. Trapella, 2022, The Journal of organic chemistry.

Development and characterization of PLGA nanoparticles as delivery systems of a prodrug of zidovudine obtained by its conjugation with ursodeoxycholic acid

E. Leo, E. Vighi, C. Contado, 2014, Drug delivery.

LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse

F. Fumagalli, M. Battistin, M. Francolini, 2020, Neurobiology of Stress.

Dystrophin restoration in skeletal, heart and skin arrector pili smooth muscle of mdx mice by ZM2 NP–AON complexes

A. Ferlini, N. Maraldi, P. Braghetta, 2010, Gene Therapy.

Molecular Hybridization as a Strategy for Developing Artemisinin-Derived Anticancer Candidates

D. Perrone, E. Marchesi, M. L. Navacchia, 2023, Pharmaceutics.

A convergent synthesis of the renin inhibitor SPP-100 using a nitrone intermediate

D. Perrone, A. Dondoni, Daniela Perrone, 2001 .

FULL PAPER UDP-GlcNAc Analogs as Inhibitors of O-GlcNAc Transferase (OGT): Spectroscopic, Computational and Biological Studies

D. Perrone, E. Marchesi, I. Delso, 2018 .