C. Tsukano

发表

Synthesis of CPZEN-45: Construction of the 1,4-Diazepin-2-one Core by the Cu-Catalyzed Intramolecular Amidation of a Vinyl Iodide.

Takuma Yoshida, Hugh Nakamura, C. Tsukano, 2016, Organic letters.

Total synthesis of (-)-caprazamycin A.

M. Yasui, Hugh Nakamura, C. Tsukano, 2015, Angewandte Chemie.

Convergent total synthesis of gymnocin-A and evaluation of synthetic analogues.

C. Tsukano, M. Sasaki, Makoto Ebine, 2005, Journal of the American Chemical Society.

Synthesis of 3-acyl-2-arylindole via palladium-catalyzed isocyanide insertion and oxypalladation of alkyne.

C. Tsukano, Y. Takemoto, Takeshi Nanjo, 2013, Organic letters.

Ellagic acid, extracted from Sanguisorba officinalis, induces G1 arrest by modulating PTEN activity in B16F10 melanoma cells

A. Kakizuka, Tomoki Yoshida, Yi-Hsun Tan, 2019, Genes to cells : devoted to molecular & cellular mechanisms.

PPARα-Mediated Positive-Feedback Loop Contributes to Cold Exposure Memory

A. Kakizuka, Tomoki Yoshida, C. Tsukano, 2019, Scientific Reports.

Synthesis of 2-Iminoindolines via Samarium Diiodide Mediated Reductive Cyclization of Carbodiimides

T. Ishida, C. Tsukano, Y. Takemoto, 2012 .

Synthesis of cis-/All- cis-Substituted Cyclopropanes through Stereocontrolled Metalation and Pd-Catalyzed Negishi Coupling.

M. Yasui, C. Tsukano, Y. Takemoto, 2018, Organic letters.

Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models.

I. Tooyama, K. Irie, C. Tsukano, 2022, ACS chemical neuroscience.

Domino Pd-catalyzed Heck cyclization and bismuth-catalyzed hydroamination: formal synthesis of elacomine and isoelacomine.

C. Tsukano, Y. Takemoto, Takeshi Nanjo, 2011, Chemistry.

Comparative cytotoxicity of gambierol versus other marine neurotoxins.

B. Espiña, M. Vieytes, L. Botana, 2011, Chemical research in toxicology.

Diverted total synthesis and biological evaluation of gambierol analogues: elucidation of crucial structural elements for potent toxicity.

M. Satake, K. Tachibana, C. Tsukano, 2004, Chemistry.

Optimization of the Linker Length in the Dimer Model of E22P-Aβ40 Tethered at Position 38.

I. Tooyama, K. Irie, C. Tsukano, 2022, ACS chemical neuroscience.

Platinum catalyzed 7-endo cyclization of internal alkynyl amides and its application to synthesis of the caprazamycin core.

C. Tsukano, Y. Takemoto, S. Yokouchi, 2012, Organic & biomolecular chemistry.

Control of 6-exo and 7-endo cyclizations of alkynylamides using platinum and bismuth catalysts.

C. Tsukano, Y. Takemoto, S. Yokouchi, 2011, Chemistry, an Asian journal.

Dearomatization Reactions of Electron‐Deficient Aromatic Rings

C. Tsukano, Y. Takemoto, 2016 .

Total synthesis of avenaol

M. Yasui, C. Tsukano, Y. Takemoto, 2017, Nature Communications.

Total Synthesis of Lyconesidine B, a Lycopodium Alkaloid with an Oxygenated, Amine-Type Fawcettimine Core.

Tomohiro Kurose, C. Tsukano, Y. Takemoto, 2020, Organic letters.

Palladium-catalyzed cascade process consisting of isocyanide insertion and benzylic C(sp3)-H activation: concise synthesis of indole derivatives.

C. Tsukano, Y. Takemoto, Takeshi Nanjo, 2012, Organic letters.

Palladium(0)-Catalyzed Benzylic C(sp3)-H Functionalization for the Concise Synthesis of Heterocycles and Its Applications.

C. Tsukano, 2017, Chemical & pharmaceutical bulletin.

Synthesis of 3,3-disubstituted indoline-2-thiones catalysed by an N-heterocyclic carbene.

T. Ishida, C. Tsukano, Y. Takemoto, 2014, Chemical communications.

Palladium-catalyzed intramolecular carboborylation of 1,3-diene and synthesis of ABCD ring of communesins.

C. Tsukano, Y. Takemoto, Sudhir M. Hande, 2019, Organic & biomolecular chemistry.

Dearomatizing conjugate addition to quinolinyl amidines for the synthesis of dehaloperophoramidine through tandem arylation and allylation.

T. Ishida, C. Tsukano, Y. Takemoto, 2013, Angewandte Chemie.

Synthesis of pyrrolophenanthridine alkaloids based on C(sp³)-H and C(sp²)-H functionalization reactions.

C. Tsukano, Y. Takemoto, N. Muto, 2014, Chemistry, an Asian journal.

Total syntheses of complanadines A and B.

E. Kwon, M. Hirama, C. Tsukano, 2013, Angewandte Chemie.

Palladium(0)‐Catalyzed CarbonHydrogen Bond Functionalization for the Synthesis of Indoloquinazolinones

C. Tsukano, Y. Takemoto, Masataka Okuno, 2014 .

Synthesis of Spirooxindoles from Carbamoyl Chlorides via Cyclopropyl Methine C(sp3)–H Activation Using Palladium Catalyst

C. Tsukano, Y. Takemoto, Masataka Okuno, 2013 .

Palladium-catalyzed amidation by chemoselective C(sp3)-H activation: concise route to oxindoles using a carbamoyl chloride precursor.

C. Tsukano, Y. Takemoto, Masataka Okuno, 2012, Angewandte Chemie.

Synthetic Approaches to Spiro-oxindoles and Iminoindolines Based on Formation of C2–C3 Bond

C. Tsukano, Y. Takemoto, 2014 .

Asymmetric synthesis of trisubstituted oxazolidinones by the thiourea-catalyzed aldol reaction of 2-isocyanatomalonate diester.

Yusuke Kobayashi, C. Tsukano, Y. Takemoto, 2014, Organic letters.

Total Synthesis of Caprazamycin A: Practical and Scalable Synthesis of syn-β-Hydroxyamino Acids and Introduction of a Fatty Acid Side Chain to 1,4-Diazepanone.

Takuma Yoshida, Yusuke Kobayashi, M. Yasui, 2019, Journal of the American Chemical Society.

Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone.

D. Siegel, S. Danishefsky, C. Tsukano, 2007, Angewandte Chemie.

Flexible Strategy for Syntheses of Spirooxindoles Using Palladium‐Catalyzed Carbosilylation and Sakurai‐Type Cyclization.

C. Tsukano, Y. Takemoto, Sudhir M. Hande, 2011 .

Synthesis of Stereoisomeric Simplified Analogs of Alotaketals toward the Elucidation of the Structural Requirements of Protein Kinase C Isozyme-Selective Binding.

K. Irie, C. Tsukano, Sogen Okuda, 2023, Organic letters.

Synthesis of Alkyl Bridged‐Tris‐α‐Amino Acids as C 3 ‐Symmetric and Linear Linkers

K. Irie, C. Tsukano, T. Imamoto, 2021, European Journal of Organic Chemistry.

Asymmetric synthesis of (-)-aurantioclavine via palladium-catalyzed intramolecular allylic amination.

C. Tsukano, Y. Takemoto, S. Suetsugu, 2014, Organic letters.

Synthesis of Octahydro- and Decahydroquinolines by a One-Pot Cascade Reaction of Tetrasubstituted Enecarbamate.

Tomohiro Kurose, C. Tsukano, Y. Takemoto, 2017, Organic letters.

Synthesis and Application of Tetrahydro-2H-fluorenes by a Pd(0)-Catalyzed Benzylic C(sp(3) )-H Functionalization.

C. Tsukano, Y. Takemoto, S. Suetsugu, 2016, Chemistry.

Total syntheses of polycyclic polyp renylated acylphloroglucinols

D. Siegel, S. Danishefsky, C. Tsukano, 2010 .

Synthesis of the ABCDG ring skeleton of communesin F based on carboborylation of 1,3-diene and Bi(OTf)3-catalyzed cyclizations

M. Yasui, C. Tsukano, Y. Takemoto, 2019, The Journal of Antibiotics.

Synthesis of highly oxidized quinolizidine via reduction of acylpyridinium cations, and total syntheses of quinolizidines 207I and 1-epi-207I.

C. Tsukano, Y. Takemoto, Iderbat Enkhtaivan, 2012, Organic letters.

Studies toward the total synthesis of gymnocin A, a cytotoxic polyether: a highly convergent entry to the F-N ring fragment.

K. Tachibana, C. Tsukano, M. Sasaki, 2002, Organic letters.

Flexible strategy for syntheses of spirooxindoles using palladium-catalyzed carbosilylation and Sakurai-type cyclization.

C. Tsukano, Y. Takemoto, Sudhir M. Hande, 2011, Organic letters.

Concise Construction of the ACDE Ring System of Calyciphylline A Type Alkaloids by a [5+2] Cycloaddition.

Hugh Nakamura, C. Tsukano, Y. Takemoto, 2019, Chemistry.

Palladium ( 0 )-Catalyzed Benzylic C ( sp 3 ) – H Functionalization for the Concise Synthesis of Heterocycles and Its Applications

C. Tsukano, 2017 .

Enantioselective Acetalization via Dynamic Kinetic Resolution for Synthesis of γ-Alkoxybutenolide by Thiourea-Quaternary Ammonium Salt Catalysts: Its Application to Strigolactones.

I. Pápai, M. Yasui, C. Tsukano, 2020, Angewandte Chemie.

Structure–activity relationship studies of gymnocin-A

C. Tsukano, M. Sasaki, 2006 .

Long-Term Oral Administration of Hop Flower Extracts Mitigates Alzheimer Phenotypes in Mice

A. Kakizuka, C. Tsukano, Y. Takemoto, 2014, PloS one.

Synthetic Study of Matrine-Type Alkaloids: Stereoselective Construction of the AB Rings of the Quinolizidine Skeleton

C. Tsukano, Y. Takemoto, Iderbat Enkhtaivan, 2014, Synlett.

Concise Total Synthesis of (±)‐Lycodine

M. Hirama, C. Tsukano, Y. Takemoto, 2010 .

Palladium-Catalyzed Double C-H Functionalization of Arenes at the Positions ortho and meta to Their Directing Group: Concise Synthesis of Benzocyclobutenes.

C. Tsukano, Y. Takemoto, Takeshi Nanjo, 2016, Chemical & pharmaceutical bulletin.

Total synthesis of gymnocin-A.

C. Tsukano, M. Sasaki, 2003, Journal of the American Chemical Society.

PPARα-Mediated Positive-Feedback Loop Contributes to Cold Exposure Memory

A. Kakizuka, Tomoki Yoshida, C. Tsukano, 2019, Scientific Reports.

Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (-)-Lycodine and (-)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities.

E. Kwon, H. Shirakawa, S. Kaneko, 2017, Chemistry.

Synthesis of the NO ring model of gymnocin-B

C. Tsukano, M. Sasaki, 2005 .

Synthesis of 8β-hydroxy-9(11),13-abietadien-12-one from (+)-dehydroabietylamine and its AhR ligand activity

C. Tsukano, T. Ishikawa, K. Nishino, 2023, Results in Chemistry.

Synthetic Studies towards Communesins: Diastereoselective Oxidative Rearrangement of Aurantioclavine Derivatives

C. Tsukano, Y. Takemoto, S. Suetsugu, 2016 .

Synthetic entry to the ABCD ring fragment of gymnocin-A, a cytotoxic marine polyether

K. Tachibana, C. Tsukano, M. Sasaki, 2003 .

Synthesis and Application of Tetrahydro‐2H‐fluorenes by a Pd(0)‐Catalyzed Benzylic C(sp3)—H Functionalization.

C. Tsukano, Y. Takemoto, S. Suetsugu, 2016 .

Total Synthesis and Structure Revision of (+)-Lancilactone C.

K. Irie, C. Tsukano, S. Suzuki, 2023, Journal of the American Chemical Society.

Studies Toward the Total Synthesis of Schinortriterpenoids: Diastereoselective Synthesis of the Left‐Hand Fragment

K. Irie, C. Tsukano, Ryotaro Yagita, 2021 .

Synthesis of 3,3-Disubstituted 2-Aminoindolenines by Palladium-Catalyzed Allylic Amidination with Isocyanide

C. Tsukano, Y. Takemoto, Takeshi Nanjo, 2014, Synlett.

Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (-)-Lycodine and (-)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities.

H. Shirakawa, S. Kaneko, C. Tsukano, 2017, Chemistry.