L. McDonald

发表

Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of their derivatives.

T. Mansour, Youjun Yang, Guy Singh, 2002, Bioorganic & medicinal chemistry letters.

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

R. Williamson, M. Siegel, G. Carter, 2002, Journal of the American Chemical Society.

FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary-skimmer CID FTMS.

G. Kruppa, M. Siegel, G. Carter, 2003, Analytical chemistry.

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.

K. Fan, R. Williamson, V. Marathias, 2007, Chirality.

Patellamide E: a new cyclic peptide from the ascidian Lissoclinum patella.

C. Ireland, L. McDonald, 1992, Journal of natural products.

Tawicyclamides A and B, new cyclic peptides from the Ascidian Lissoclinum patella: studies on the solution- and solid-state conformations

J. Clardy, M. Foster, C. Ireland, 1992 .

Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.

B. Moore, P. Jensen, F. Koehn, 2011, Journal of the American Chemical Society.

Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines

R. Abraham, P. Cai, J. Levin, 2007, Molecular Cancer Therapeutics.

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

R. Williamson, M. Siegel, G. Carter, 2002, Journal of the American Chemical Society.

Uridyl Peptide Antibiotics: Developments in Biosynthesis and Medicinal Chemistry

G. Carter, L. McDonald, 2014 .

Depsides isolated from the Sri Lankan lichen Parmotrema sp. exhibit selective Plk1 inhibitory activity

David E. Williams, R. Andersen, F. Loganzo, 2011, Pharmaceutical biology.

Botryllamides A-D, new brominated tyrosine derivatives from styelid ascidians of the genus Botryllus

A. Carroll, C. Ireland, C. Fairchild, 1995 .

Biomedical Potential of Marine Natural Products

D. Radisky, M. Foster, C. Ireland, 1993 .

Rare 1 , 2 ’-binaphthyls Produced by Nodulisporium hinnuleum Smith ( ATCC 36102 )

F. Koehn, L. McDonald, G. Schlingmann, 2011 .

Absolute stereochemistry of the spiroxins

K. Nakanishi, N. Berova, G. Carter, 2001 .

Spiroxins, DNA cleaving antitumor antibiotics from a marine-derived fungus

C. Discafani, G. Carter, L. McDonald, 1999 .

Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II.

G. Eldredge, C. Ireland, L. Barrows, 1994, Journal of medicinal chemistry.

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived Xylariaceous fungus LL-07H239.

P. Lassota, G. Carter, L. McDonald, 2004, Journal of natural products.

Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine.

D. Powell, J. Levin, L. Toral-Barza, 2009, Journal of medicinal chemistry.

Fibrosterol sulfates from the Philippine sponge Lissodendoryx (Acanthodoryx) fibrosa: sterol dimers that inhibit PKCzeta.

M. K. Harper, C. Ireland, T. Bugni, 2009, The Journal of organic chemistry.

Fermentative production of self-toxic fungal secondary metabolites

L. McDonald, L. Barbieri, M. P. Singh, 2010, Journal of Industrial Microbiology & Biotechnology.

Bioactive compounds from the sea

D. Radisky, M. Foster, C. Ireland, 2000 .

In support of the original medermycin/lactoquinomycin A structure.

R. Williamson, G. Carter, L. McDonald, 2002, Organic letters.

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

M. Pangalos, B. Ruan, J. Skotnicki, 2008, Proceedings of the National Academy of Sciences.

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Christine J. Martin, Lesley S. Sheehan, M. Gregory, 2017, Nature Communications.

Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.

Eric I. Rossman, A. Alimardanov, L. Di, 2009, Journal of medicinal chemistry.

Recombinant strains for the enhanced production of bioengineered rapalogs.

Christine J. Martin, Teresa A. Foster, M. Gregory, 2013, Metabolic engineering.

Stereoselective synthesis of an active metabolite of the potent PI3 kinase inhibitor PKI-179.

T. Mansour, S. Ayral-Kaloustian, L. McDonald, 2010, The Journal of organic chemistry.

Namenamicin, a New Enediyne Antitumor Antibiotic from the Marine Ascidian Polysyncraton lithostrotum.

C. Ireland, C. Discafani, G. Krishnamurthy, 1997 .

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Markiyan Samborskyy, Mohammad Nur-E-Alam, Alexander Alanine, 2017, Nature Communications.