O. Vechorkin

发表

Cross-coupling of nonactivated alkyl halides with alkynyl Grignard reagents: a nickel pincer complex as the catalyst.

R. Scopelliti, Xile Hu, Aurélien Godinat, 2011, Angewandte Chemie.

Carbon dioxide as the C1 source for direct C-H functionalization of aromatic heterocycles.

Xile Hu, O. Vechorkin, N. Hirt, 2010, Organic letters.

A structure-activity study of Ni-catalyzed alkyl-alkyl Kumada coupling. Improved catalysts for coupling of secondary alkyl halides.

R. Scopelliti, Peng Ren, Xile Hu, 2011, Journal of the American Chemical Society.

Nickel complexes of a pincer NN2 ligand: multiple carbon-chloride activation of CH2Cl2 and CHCl3 leads to selective carbon-carbon bond formation.

R. Scopelliti, Xile Hu, O. Vechorkin, 2008, Journal of the American Chemical Society.

Ni-catalyzed Sonogashira coupling of nonactivated alkyl halides: orthogonal functionalization of alkyl iodides, bromides, and chlorides.

Xile Hu, O. Vechorkin, D. Barmaz, 2009, Journal of the American Chemical Society.

Nickel-catalyzed cross-coupling of non-activated and functionalized alkyl halides with alkyl Grignard reagents.

Xile Hu, O. Vechorkin, 2009, Angewandte Chemie.

Nickel complexes of a pincer amidobis(amine) ligand: synthesis, structure, and activity in stoichiometric and catalytic C-C bond-forming reactions of alkyl halides.

R. Scopelliti, Xile Hu, O. Vechorkin, 2009, Chemistry.

Potent and Selective Biaryl Amide Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1).

M. Covington, S. Diamond, E. Behshad, 2022, ACS medicinal chemistry letters.

Discovery of Pyrazolopyridine Derivatives as HPK1 Inhibitors.

M. Covington, S. Diamond, E. Behshad, 2022, ACS medicinal chemistry letters.

The nickel/copper-catalyzed direct alkylation of heterocyclic C-H bonds.

Xile Hu, Oleg Vechorkin, Valérie Proust, 2010, Angewandte Chemie.

Why are (NN2)Ni pincer complexes active for alkyl-alkyl coupling: ß-H elimination is kinetically accessible but thermodynamically uphill

C. Corminboeuf, R. Scopelliti, Xile Hu, 2010 .

Functional group tolerant Kumada-Corriu-Tamao coupling of nonactivated alkyl halides with aryl and heteroaryl nucleophiles: catalysis by a nickel pincer complex permits the coupling of functionalized Grignard reagents.

Xile Hu, O. Vechorkin, V. Proust, 2009, Journal of the American Chemical Society.

Pd, Pt, and Ru complexes of a pincer bis(amino)amide ligand.

R. Scopelliti, Peng Ren, Xile Hu, 2011, Dalton transactions.

Synthesis and electronic properties of a pentafluoroethyl-derivatized nickel pincer complex.

Peng Ren, Xile Hu, D. Vicic, 2012, Dalton transactions.

A Well-Defined Ni Pincer Catalyst for Cross Coupling of Non-Activated Alkyl Halides and Direct C-H Alkylation

O. Vechorkin, 2011 .

Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3.

H. Koblish, M. Deller, R. Klabe, 2022, Journal of medicinal chemistry.

Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach.

April Horsey, L. Leffet, M. Covington, 2023, ACS medicinal chemistry letters.

Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3

H. Koblish, M. Deller, R. Klabe, 2022, Journal of Medicinal Chemistry.