M. Garbarg

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Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

J. Schwartz, J. Arrang, M. Garbarg, 1983, Nature.

Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.

J. Schwartz, H. Stark, J. Arrang, 1996, Journal of medicinal chemistry.

Decrease in histamine content and decarboxylase activities in an isolated area of the cerebral cortex of the cat

J. Hirsch, J. Schwartz, G. Barbin, 1975, Brain Research.

Hypersensitivity to histamine in the guinea-pig brain: Microiontophoretic and biochemical studies

H. Haas, J. Schwartz, J. Palacios, 1978, Brain Research.

The histamine H3 receptor and its ligands.

J. Schwartz, H. Stark, J. Arrang, 2001, Progress in medicinal chemistry.

Synthesis of Potent Non‐imidazole Histamine H3‐Receptor Antagonists

J. Schwartz, J. Arrang, C. Ganellin, 1998, Archiv der Pharmazie.

Histamine Receptors in Brain

M. Bouthenet, J. Schwartz, J. Arrang, 1991 .

Histamine receptors in brain as targets for tricyclic antidepressants

J. Schwartz, M. Garbarg, T. T. Quach, 1981 .

Mast cell specific proteases in rat brain: changes in rats with experimental allergic encephalomyelitis

J. Schwartz, M. Garbarg, A. Rouleau, 2005, Journal of Neural Transmission.

Rat cerebral mast cells undergo phenotypic changes during development.

J. Schwartz, M. Garbarg, X. Ligneau, 1996, Brain research. Developmental brain research.

Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions

J. Schwartz, M. Garbarg, A. Rouleau, 1997, Neuroscience.

BRAIN HISTIDINE DECARBOXYLASE ACTIVITY IN PARKINSON'S DISEASE

Y. Agid, J. Schwartz, F. Javoy‐Agid, 1983, The Lancet.

Histamine and histidine decarboxylase in brain stem nuclei: distribution and decrease after lesions

J. Schwartz, C. Llorens-Cortes, H. Pollard, 1978, Brain Research.

Inhibition of Histamine Synthesis in Brain by α‐Fluoromethylhistidine, a New Irreversible Inhibitor: In Vitro and In Vivo Studies

J. Schwartz, G. Barbin, M. Garbarg, 1980, Journal of neurochemistry.

Histamine H3-receptor-mediated inhibition of calcitonin gene-related peptide release from cardiac C fibers. A regulatory negative-feedback loop.

M. Garbarg, R. Levi, N. C. Smith, 1996, Circulation research.

Highly Potent and Selective Ligands for a New Class H3 of Histamine Receptor

J. Schwartz, J. Arrang, J. Lecomte, 1988, Investigative radiology.

New potent histamine H3-receptor antagonists of the amide type

J. Schwartz, H. Stark, J. Arrang, 1995 .

Acylated and alkylated histamine derivatives as new histamine H3-receptor antagonists

J. Schwartz, H. Stark, J. Arrang, 1994 .

Histaminergic pathway in rat brain evidenced by lesions of the medial forebrain bundle.

J. Féger, J. Schwartz, G. Barbin, 1974, Science.

Histamine receptors in the brain.

J. Schwartz, M. Garbarg, 1985, New England and regional allergy proceedings.

A third histamine receptor subtype: Characterisation, localisation and functions of the H3-receptor

J. Schwartz, J. Arrang, H. Pollard, 1990, Agents and Actions.

Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors

J. Schwartz, J. Arrang, M. Garbarg, 1987, Neuroscience.

Autoregulation of histamine release in brain by presynaptic H3-receptors

J. Schwartz, J. Arrang, M. Garbarg, 1985, Neuroscience.

Dehydration-induced release of vasopressin involves activation of hypothalamic histaminergic neurons.

A. Kjaer, U. Knigge, J. Warberg, 1994, Endocrinology.

Phenotypic and quantitative changes in mast cells after syngeneic unilateral lung transplantation in the rat.

J. Schwartz, N. Frossard, M. Garbarg, 1996, Clinical science.

Histamine receptors in the brain: characterization by binding studies and biochemical effects.

J. Schwartz, J. Palacios, A. Duchemin, 1980, Advances in biochemical psychopharmacology.

Augmentation in hypothalamic histamine induced by diencephalic lesions in rats

J. Féger, J. Schwartz, M. Garbarg, 1973, Agents and Actions.

Histaminergic transmission in the mammalian brain.

J. Schwartz, J. Arrang, H. Pollard, 1991, Physiological reviews.

Enzyme-catalyzed prodrug approaches for the histamine H3-receptor agonist (R)-α-methylhistamine

J. Schwartz, H. Stark, M. Garbarg, 2001 .

Bioavailability, antinociceptive and antiinflammatory properties of BP 2-94, a histamine H3 receptor agonist prodrug.

P. Lavie, J. Schwartz, H. Stark, 1997, The Journal of pharmacology and experimental therapeutics.

Modulation of pentagastrin-induced histamine release by histamine H3 receptors in the dog.

J. Schwartz, S. Bertini, M. Garbarg, 1996, Scandinavian journal of gastroenterology.

Molecular and Functional Diversity of Histamine Receptor Subtypes

J. Schwartz, G. Drutel, J. Arrang, 1995, Annals of the New York Academy of Sciences.

The histamine H3 receptor: pharmacology and potential therapeutic applications.

J. Schwartz, M. Garbarg, 1993, Annales francaises d'anesthesie et de reanimation.

S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist.

J. Schwartz, J. Arrang, C. Ganellin, 1992, The Journal of pharmacology and experimental therapeutics.

Design of an Affinity Matrix for Purification of the Histamine H1 Receptor from Guinea Pig Cerebellum

J. Schwartz, M. Garbarg, M. Ruat, 1992, Journal of neurochemistry.

Histamine H3 receptors : novel ligands and responses

J. Schwartz, M. Dam, J. Arrang, 1992 .

Modulation of Histamine Synthesis and Release in Brain via Presynaptic Autoreceptors and Heteroreceptors

J. Schwartz, J. Arrang, H. Pollard, 1990, Annals of the New York Academy of Sciences.

Fasting or dexamethasone treatment reduce protease content in rat lung mast cells and modulation of histamine synthesis by H3 receptors

J. Schwartz, M. Garbarg, A. Rouleau, 1994, Agents and Actions.

Synergism between histamine H1- and H2-receptors in the cAMP response in guinea pig brain slices: effects of phorbol esters and calcium.

J. Schwartz, M. Garbarg, 1988, Molecular pharmacology.

Circadian rhythm of histamine in the pineal gland.

J. Schwartz, M. Garbarg, C. julien, 1974, Life sciences.

Three classes of histamine receptors in brain

J. Schwartz, J. Arrang, M. Garbarg, 1986 .

Histamine synthesizing afferents within the amygdaloid complex and bed nucleus of the stria terminalis of the rat

Y. Ben-Ari, J. Schwartz, G. Salle, 1977, Brain Research.

4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.

J. Schwartz, H. Stark, M. Garbarg, 1998, Journal of medicinal chemistry.

A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.

J. Schwartz, B. Bang-Andersen, C. Ganellin, 1996, Journal of medicinal chemistry.

[125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors.

J. Schwartz, H. Stark, J. Díaz, 1994, The Journal of pharmacology and experimental therapeutics.

Synthesis, X-ray crystallography, and pharmacokinetics of novel azomethine prodrugs of (R)-alpha-methylhistamine: highly potent and selective histamine H3 receptor agonists.

J. Schwartz, H. Stark, M. Garbarg, 1995, Journal of medicinal chemistry.

Histaminergic Transmission in the Brain

J. Schwartz, H. Pollard, M. Garbarg, 2011 .

A detailed mapping of hist amine H1-receptors in guinea-pig central nervous system established by autoradiography with [125I]iodobolpyramine

M. Bouthenet, N. Salès, J. Schwartz, 1988, Neuroscience.

Pharmacological characterization of histamine receptors mediating the stimulation of cyclic AMP accumulation in slices from guinea-pig hippocampus.

J. Schwartz, J. Palacios, G. Barbin, 1978, Molecular Pharmacology.

Highly potent and selective ligands for histamine H3-receptors

J. Schwartz, J. Arrang, J. Lecomte, 1987, Nature.

Sensitive Radioimmunoassays for Histamine and tele‐Methylhistamine in the Brain

J. Schwartz, H. Pollard, M. Garbarg, 1989, Journal of neurochemistry.

Pharmacological specificity of brain histamine H2-receptors differs in intact cells and cell-free preparations

J. Schwartz, M. Garbarg, M. Tuong, 1980, Nature.

Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain.

J. Schwartz, M. Garbarg, C. Gros, 1989, European journal of pharmacology.

Properties and roles of the three subclasses of histamine receptors in brain.

J. Schwartz, M. Korner, J. Arrang, 1986, The Journal of experimental biology.

Actions of betahistine at histamine receptors in the brain.

J. Schwartz, E. Yeramian, J. Arrang, 1985, European journal of pharmacology.

Interaction between mianserin, an antidepressant drug, and central H1- and H2-histamine-receptors: In vitro and in vivo studies and radioreceptor assay

J. Schwartz, J. Arrang, M. Garbarg, 1983, Neuropharmacology.

Histamine Receptors and Actions in Mammalian Brain

J. Schwartz, M. Garbarg, T. T. Quach, 1983 .

Chapter Nine – Histamine Receptors in the Brain and Their Possible Functions

J. Schwartz, A. Duchemin, H. Pollard, 1982 .

Involvement of histaminergic neurons in arousal mechanisms demonstrated with H3-receptor ligands in the cat

J. Schwartz, M. Jouvet, G. Vanni-Mercier, 1990, Brain Research.

[125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.

J. Schwartz, H. Stark, M. Garbarg, 1996, Journal of medicinal chemistry.

Design of potent non-thiourea H3-receptor histamine antagonists.

J. Schwartz, J. Arrang, M. Garbarg, 1995, Journal of medicinal chemistry.

Synthesis, absolute configuration, stereoselectivity, and receptor selectivity of (alpha R, beta S)-alpha,beta-dimethylhistamine, a novel high potent histamine H3 receptor agonist.

J. Schwartz, J. Arrang, M. Garbarg, 1992, Journal of medicinal chemistry.

RELATIONSHIP BETWEEN LIPOPHILICITY AND BRAIN UPTAKE OF AZOMETHINE PRODRUGSOF A HISTAMINE H3-RECEPTOR AGONIST

J. Schwartz, H. Stark, M. Garbarg, 1996 .

Synthesis and histamine H3-receptor agonist activity of mono- and dialkyl-substituted histamine derivatives†

J. Schwartz, H. Stark, J. Arrang, 1995 .

Imetit and N-methyl derivatives. The transition from potent agonist to antagonist at histamine H3 receptors.1

J. Schwartz, J. Arrang, B. Bang-Andersen, 1992 .

P84 novel potent histamine H3-receptor antagonists

J. Schwartz, H. Stark, M. Garbarg, 1994 .

Responses of anterior pituitary hormones and hypothalamic histamine to blockade of histamine synthesis and to selective activation or inactivation of presynaptic histamine H3 receptors in stressed rats.

J. Schwartz, A. Kjaer, U. Knigge, 1993, Neuroendocrinology.

[125I]Iodobolpyramine, a highly sensitive probe for histamine H1-receptors in guinea-pig brain.

M. Bouthenet, N. Salès, J. Schwartz, 1986, European journal of pharmacology.

Iodobolpyramine and other iodinated derivatives as ligands for detecting histamine H1 receptors

J. Schwartz, M. Korner, C. Ganellin, 1987 .

The regulation of gastric histidine decarboxylase activity. I. Effect of pyridoxine deficiency.

M. Garbarg, B. Halpern, 1971, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

The regulation of gastric histidine decarboxylase activity. II. Effects of physiological stimuli during pyridoxine deficiency.

M. Garbarg, B. Halpern, 1971, Life sciences. Pt. 2: Biochemistry, general and molecular biology.

Characterization of histamine H1-receptor binding peptides in guinea pig brain using [125I]iodoazidophenpyramine, an irreversible specific photoaffinity probe.

J. Schwartz, M. Korner, C. Ganellin, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Dual localization of histamine in an ascending neuronal pathway and in non-neuronal cells evidenced by lesions in the lateral hypothalamic area

J. Schwartz, H. Pollard, G. Barbin, 1976, Brain Research.

Autoreceptors and Heteroreceptors Evidenced by Histamine H3 Receptor Ligands

J. Schwartz, H. Stark, J. Arrang, 1991 .

New aspects of the role of histamine in cardiovascular function: identification, characterization, and potential pathophysiological importance of H3 receptors.

J. Schwartz, J. Hey, M. Garbarg, 1995, Canadian journal of physiology and pharmacology.

Metabolism and functions of histamine in the brain.

M. Baudry, M. Martres, J. Schwartz, 1979, Current developments in psychopharmacology.

Effects of mesencephalic and hypothalamic lesions on histamine levels in rat brain.

J. Féger, J. Schwartz, M. Garbarg, 1973, Brain research.

l‐Histidine Decarboxylase in the Human Brain: Properties and Localization

P. Gaspar, Y. Agid, J. Palacios, 1980, Journal of neurochemistry.

Simultaneous presence of histamine-N-methyltransferase and catechol-O-methyltransferase in neuronal and glial cells in culture

M. Baudry, J. Schwartz, M. Garbarg, 1975, Brain Research.

Role of hypothalamic histaminergic neurons in mediation of ACTH and beta-endorphin responses to LPS endotoxin in vivo.

A. Kjaer, U. Knigge, H. Jørgensen, 1994, Neuroendocrinology.

HISTAMINE SYNTHESIZING AFFERENTS TO THE HIPPOCAMPAL REGION

J. Storm-Mathisen, G. Barbin, M. Garbarg, 1976, Journal of neurochemistry.

Modulation of acetylcholine, capsaicin and substance P effects by histamine H3 receptors in isolated perfused rabbit lungs.

P. Gustin, M. Ansay, M. Garbarg, 1995, European journal of pharmacology.

The Relationship between Functional Inhibition and Binding for KCa2 Channel Blockers

Guy W J Moss, M. Garbarg, D. C. H. Benton, 2013, PloS one.

Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues.

M. Garbarg, W. Schunack, S. Elz, 1995, Journal of medicinal chemistry.

The histamine H3-receptor: pharmacology, roles and clinical implications studied with agonists.

J. Schwartz, H. Stark, J. Arrang, 1991, Agents and actions. Supplements.

N-ethylmaleimide-induced changes in agonist affinity for histamine H1-receptors in the guinea pig brain.

J. Schwartz, E. Yeramian, M. Garbarg, 1985, Molecular pharmacology.

Synthesis, X‐Ray Crystallography, and Pharmacokinetics of Novel Azomethine Prodrugs of (R)‐α‐Methylhistamine: Highly Potent and Selective Histamine H3 Receptor Agonists.

J. Schwartz, H. Stark, M. Garbarg, 1996 .

Histaminergic Systems in Brain

J. Schwartz, J. Palacios, H. Pollard, 1979 .

Histamine H3 receptors in the brain: potent and selective ligands.

J. Schwartz, J. Arrang, H. Pollard, 1989, Psychopharmacology series.

Evidence for a specific decarboxylase involved in histamine synthesis in an ascending pathway in rat brain

J. Schwartz, H. Pollard, G. Barbin, 1974, Agents and Actions.

Structure-activity relationships of novel azomethine prodrugs of the histamine H3-receptor agonist (R)-alpha-methylhistamine: from alkylaryl to substituted diaryl derivatives.

J. Schwartz, H. Stark, M. Garbarg, 1996, Die Pharmazie.

The Third Histamine Receptor

J. Schwartz, J. Arrang, J. Lecomte, 1989 .

A pharmaceutical composition containing a-methylhistamine

J. Schwartz, J. Arrang, M. Garbarg, 1985 .

New Potent Azomethine Prodrugs of the Histamine H3‐Receptor Agonist (R)‐α‐Methylhistamine Containing a Heteroarylphenyl Partial Structure

J. Schwartz, H. Stark, M. Garbarg, 1996, Archiv der Pharmazie.

Functional relationship between mast cells and C-sensitive nerve fibres evidenced by histamine H3-receptor modulation in rat lung and spleen.

J. Schwartz, M. Garbarg, A. Rouleau, 1994, Clinical science.

Characterization of the high-affinity binding sites of [3H]histamine in rat brain.

J. Schwartz, J. Palacios, G. Barbin, 1980, Molecular pharmacology.

Novel chiral H3-receptor agonists.

J. Schwartz, J. Arrang, M. Garbarg, 1991, Agents and actions. Supplements.