A. Mcelroy

发表

Synthesis of macrocyclic, potential protease inhibitors using a generic scaffold.

John P. Overington, M. Wythes, Estelle Dumez, 2002, The Journal of organic chemistry.

Matrix metalloproteinase inhibitors containing a (carboxyalkyl)amino zinc ligand: modification of the P1 and P2' residues.

M. Foley, D. Drewry, F. Brown, 1994 .

New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.

A. Mcelroy, N. Taylor, J. Pritchard, 1995, Journal of medicinal chemistry.

Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists.

A. Mcelroy, R. Hagan, S. Ireland, 1992, Journal of medicinal chemistry.

Patent Update: Neurokinin Receptor Antagonists

A. Mcelroy, 1993 .

Matrix metalloproteinase inhibitors containing a (carboxyalkyl)amino zinc ligand: modification of the P1 and P2' residues.

M. Foley, D. Drewry, F. Brown, 1994, Journal of medicinal chemistry.

Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents.

P. Fish, S. Bailey, James E. J. Mills, 2008, Bioorganic & medicinal chemistry letters.

Diastereoselective epoxidation of allylic phosphine oxides

A. Mcelroy, J. Clayden, E. Egert, 1994 .

Stereochemical control (E/Z and syn/anti) by the diphenylphosphinoyl group in the synthesis of allylic alcohols by allylic rearrangement and by 1,4-diastereoselective reduction of enones

A. Mcelroy, J. Clayden, S. J. Martin, 1993 .

The synthesis of (Z)-penta-2,4-dien-1-ol and substituted (E)-pentadienols by the stereochemically controlled Horner–Wittig reaction

A. Mcelroy, N. Greeves, S. Warren, 1991 .

Stereocontrolled synthesis of δ-hydroxy allylic phosphine oxides by allylic ester transposition

A. Mcelroy, S. Warren, 1985 .

Transposition of allylic alcohols controlled by the Ph2PO group: Reagents for α-hydroxy-diene synthesis by the horner-wittig reaction

A. Mcelroy, S. Warren, P. S. Brown, 1985 .

Stereocontrolled (E, Z and erythro, threo) synthesis of β-hydroxyallylic sulphides

A. Mcelroy, S. Warren, 1985 .

Control over absolute (R,S), relative (syn,anti) and geometrical (E,Z) stereochemistry in the synthesis of allylically substituted alkenes from diphenylphosphinoyl epoxy alcohols

A. Mcelroy, J. Clayden, S. Warren, 1995 .

Stereoselective peracid epoxidation of allylic and δ-hydroxyallylic diphenylphosphine oxides

A. Mcelroy, S. Warren, 1985 .

New kappa-receptor agonists based upon a 2-[(alkylamino)methyl]piperidine nucleus.

D. S. Brown, D. Belton, D. Scopes, 1992, Journal of medicinal chemistry.

Characterisation, CNS distribution and function of NK2 receptors studied using potent NK2 receptor antagonists

E. Kawashima, A. Mcelroy, R. Hagan, 1993, Regulatory Peptides.

Low molecular weight neurokinin NK2 antagonists

A. Mcelroy, J. Pritchard, R. Hagan, 1993 .

Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor.

A. Mcelroy, R. Hagan, S. Ireland, 1992, Journal of medicinal chemistry.

Synthesis, antinociceptive activity, and opioid receptor profiles of 10-substituted-6-oxamorphinans

D. Scopes, A. Mcelroy, A. Hayes, 1990 .

Design of selective thrombin inhibitors based on the (R)-Phe-Pro-Arg sequence.

John P. Overington, K. James, A. Brown, 2002, Journal of medicinal chemistry.

Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.

M. Bunnage, K. Beaumont, J. Blagg, 2007, Journal of medicinal chemistry.

Regiospecific synthesis of enones via α-(phenylthio)-ketones: 2,5-dimethyl-4-hexen-3-one, E-6-methyl-2-hepten-4-one, E-7-methyl-4-octen-3-one, and ar-turmerone

A. Mcelroy, S. Warren, J. Elliott, 1983 .

Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor.

A M Hassell, M. Lambert, D. Drewry, 1994, Science.

NK2 antagonists and the role of NK2 receptors

A. Mcelroy, J. Pritchard, R. Hagan, 1992, Regulatory Peptides.

Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

Julian Blagg, P. Fish, R. Butt, 2007, Journal of medicinal chemistry.

Paul W Smith, A. Mcelroy, J. Pritchard, 1994 .