H. Hoang

发表

Alpha-turn mimetics: short peptide alpha-helices composed of cyclic metallopentapeptide modules.

James P Snyder, J. Snyder, D. Fairlie, 2004, Journal of the American Chemical Society.

Single turn peptide alpha helices with exceptional stability in water.

D. Fairlie, H. Hoang, Nicholas E. Shepherd, 2005, Journal of the American Chemical Society.

Alpha helix nucleation by a simple cyclic tetrapeptide

D. Fairlie, Renée L. Beyer, H. Hoang, 2016 .

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

E. Letouzé, D. Fairlie, P. Young, 2006, Journal of the American Chemical Society.

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1

D. Fairlie, J. Mason, H. Hoang, 2013, PloS one.

The First Solution Stucture of a Single α-Helical Turn. A Pentapeptide α-Helix Stabilized by a Metal Clip

David P. Fairlie, D. Fairlie, M. Kelso, 2000 .

Metal clips induce folding of a short unstructured peptide into an alpha-helix via turn conformations in water. Kinetic versus thermodynamic products.

D. Fairlie, Renée L. Beyer, H. Hoang, 2004, Journal of the American Chemical Society.

Helix Nucleation by the Smallest Known α-Helix in Water.

D. Fairlie, Renée L. Beyer, H. Hoang, 2016, Angewandte Chemie.

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice.

D. Fairlie, H. Hoang, Nicholas E. Shepherd, 2010, Journal of medicinal chemistry.

New insights into growth hormone action.

M. Waters, D. Fairlie, H. Hoang, 2006, Journal of molecular endocrinology.

Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake

D. Fairlie, H. Hoang, Junxian Lim, 2022, RSC chemical biology.

Evaluation of Novel Carbon Nano-tube Particles in the Bacterial and Viral DNA and RNA Extraction from the Clinical Samples

H. Pham, S. T. Pham, H. Hoang, 2010 .

Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A.

D. Fairlie, H. Hoang, R. Lohman, 2012, Organic letters.

Metal clips that induce unstructured pentapeptides to be alpha-helical in water.

D. Fairlie, H. Hoang, T. Appleton, 2009, Journal of the American Chemical Society.

Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops.

D. Fairlie, B. Flanagan, H. Hoang, 2006, Organic letters.

Folding pentapeptides into left and right handed alpha helices

D. Fairlie, H. Hoang, G. Abbenante, 2012 .

Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds.

D. Fairlie, H. Hoang, Nicholas E. Shepherd, 2009, Journal of the American Chemical Society.

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.

Martin J. Stoermer, D. Craik, David A. Price, 2014, ACS medicinal chemistry letters.

A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin

David P. Fairlie, D. Fairlie, M. Kelso, 2003 .

Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability.

D. Fairlie, H. Hoang, T. Hill, 2020, Angewandte Chemie.

Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides

Alun Jones, D. Fairlie, A. Lucke, 2015, Chembiochem : a European journal of chemical biology.

Amyloid formation from an α-helix peptide bundle is seeded by 3(10)-helix aggregates.

A. McDowall, S. Bottomley, D. Fairlie, 2011, Chemistry.

Improving on nature: making a cyclic heptapeptide orally bioavailable.

Spiros Liras, David J Craik, D. Craik, 2014, Angewandte Chemie.

Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.

A. Mathiowetz, P. Loria, David A. Price, 2015, Journal of medicinal chemistry.

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.

D. Fairlie, H. Hoang, Nicholas E. Shepherd, 2015, Vitamins and hormones.

Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding

D. Fairlie, M. Kelso, Renée L. Beyer, 2014 .

Protein α-turns recreated in structurally stable small molecules.

A. Mark, D. Fairlie, A. Malde, 2011, Angewandte Chemie.

High Cell Permeability Does Not Predict Oral Bioavailability for Analogues of Cyclic Heptapeptide Sanguinamide A

D. Fairlie, H. Hoang, T. Hill, 2020 .

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

D. Fairlie, P. Young, H. Hoang, 2010, Proceedings of the National Academy of Sciences.

Glucuronic acid as a helix-inducing linker in short peptides.

D. Fairlie, H. Hoang, Chongyang Wu, 2018, Chemical communications.

Comparative α-helicity of cyclic pentapeptides in water.

David A. Price, S. Liras, D. Fairlie, 2014, Angewandte Chemie.

Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities.

D. Fairlie, H. Hoang, T. Hill, 2019, Chemical communications.

Helical structure in cyclic peptides: effect of N-methyl amides versus esters.

D. Fairlie, H. Hoang, Chongyang Wu, 2022, Chemical communications.

Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability.

D. Fairlie, S. R. Perry, H. Hoang, 2018, Organic & biomolecular chemistry.

Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation.

D. Fairlie, M. Kelso, Renée L. Beyer, 2008, Inorganic chemistry.

Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids.

D. Fairlie, M. Cooper, H. Hoang, 2015, Chemical communications.

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

P. Loria, David A. Price, S. Liras, 2017, European journal of medicinal chemistry.

Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides

D. Fairlie, H. Hoang, Junxian Lim, 2022, Angewandte Chemie.

A cyclic beta-strand tripeptide with an alpha-helix like CD spectrum.

D. Fairlie, H. Hoang, G. Abbenante, 2009, Organic letters.

Improving on nature: making a cyclic heptapeptide orally bioavailable.

D. Craik, S. Liras, D. Fairlie, 2014, Angewandte Chemie.

A novel long-range n to π* interaction secures the smallest known α-helix in water.

D. Fairlie, H. Hoang, Chongyang Wu, 2019, Angewandte Chemie.

Metal clips that induce unstructured pentapeptides to be alpha-helical in water.

D. Fairlie, H. Hoang, T. Appleton, 2009, Journal of the American Chemical Society.