Kazu Yamamoto

发表

PET by MRI: Glucose Imaging by 13C-MRS without Dynamic Nuclear Polarization by Noise Suppression through Tensor Decomposition Rank Reduction

Albert P. Chen, P. Choyke, H. Merkle, 2018, bioRxiv.

Distinguishing Closely Related Pancreatic Cancer Subtypes In Vivo by 13C Glucose MRI without Hyperpolarization

James B. Mitchell, Albert P. Chen, P. Choyke, 2019, bioRxiv.

Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

Shingo Matsumoto, Hellmut Merkle, Galen Reed, 2019, eLife.

Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization

Hellmut Merkle, Galen Reed, Murali C Krishna, 2019, Scientific Reports.

Synthesis of [1‐13C‐5‐12C]‐alpha‐ketoglutarate enables noninvasive detection of 2‐hydroxyglutarate

K. Camphausen, Natsuko Miura, J. Brender, 2021, NMR in biomedicine.

Structure-based relaxation analysis reveals C-terminal [1-13C]glycine-d2 in peptides has long spin-lattice relaxation time that is applicable to in vivo hyperpolarized magnetic resonance studies

H. Nonaka, M. Matsuo, Y. Takakusagi, 2022 .

PEGPH20, a PEGylated human hyaluronidase, induces radiosensitization by reoxygenation in pancreatic cancer xenografts. A molecular imaging study

James B. Mitchell, Jisook Lee, M. Krishna, 2022, bioRxiv.

Evofosfamide and Gemcitabine Act Synergistically in Pancreatic Cancer Xenografts by Dual Action on Tumor Vasculature and Inhibition of Homologous Recombination DNA Repair

James B. Mitchell, M. Krishna, S. Kishimoto, 2022, bioRxiv.

Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma

James B. Mitchell, P. Choyke, J. Brender, 2020, Cancer Research.

Continuous monitoring of postirradiation reoxygenation and cycling hypoxia using electron paramagnetic resonance imaging

Y. Takakusagi, T. Kawai, M. Krishna, 2022, NMR in biomedicine.

Rapid 13C Hyperpolarization of the TCA Cycle Intermediate α-Ketoglutarate via SABRE-SHEATH.

J. Ettedgui, E. Chekmenev, M. Krishna, 2022, Analytical chemistry.

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

James B. Mitchell, D. Urban, W. Linehan, 2020, Cell reports.

Synthesis and evaluation of 13C‐labeled 5‐5‐dimethyl‐1‐pyrroline‐N‐oxide aimed at in vivo detection of reactive oxygen species using hyperpolarized 13C‐MRI

James B. Mitchell, J. Brender, S. Matsumoto, 2019, Free radical biology & medicine.

Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade

James B. Mitchell, J. Brender, M. Krishna, 2021, Cancer Research.

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

James B. Mitchell, D. Citrin, M. Matsuo, 2018, Clinical Cancer Research.

Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

James B. Mitchell, M. Krishna, S. Kishimoto, 2020, bioRxiv.

Structure-guided design enables development of a hyperpolarized molecular probe for the detection of aminopeptidase N activity in vivo

Y. Takakusagi, Yohei Kondo, S. Sando, 2022, Science advances.

Imaging of Glucose Metabolism by 13 C-MRI Distinguishes Pancreatic Cancer Subtypes 1 in Mice 2 3

Krishna, James B. Mitchell, P. Choyke, 2022 .

Real-Time insight into in vivo redox status utilizing hyperpolarized [1-13C] N-acetyl cysteine

James B. Mitchell, P. Choyke, W. Linehan, 2021, Scientific Reports.

Simple Esterification of [1-13C]-Alpha-Ketoglutarate Enhances Membrane Permeability and Allows for Noninvasive Tracing of Glutamate and Glutamine Production.

K. Camphausen, Natsuko Miura, J. Brender, 2021, ACS chemical biology.

Three-dimensional alginate hydrogels for radiobiological and metabolic studies of cancer cells.

Jason Y. Cheng, Nallathamby Devasahayam, Murali C. Krishna, 2018, Colloids and surfaces. B, Biointerfaces.

Reoxygenation after Evofosfamide Treatment in Pancreatic Ductal Adenocarcinoma Xenografts is due to Decreased Oxygen Consumption and not Increased Oxygen Supply

James B. Mitchell, J. Brender, M. Krishna, 2020, bioRxiv.

Evaluation of a deuterated triarylmethyl spin probe for in vivo R2*-based EPR oximetric imaging with enhanced dynamic range

J. Brender, S. Kishimoto, Kazu Yamamoto, 2023, bioRxiv.

Hypoxia activated prodrug evofosfamide treatment in pancreatic ductal adenocarcinoma xenografts alters the tumor redox status to potentiate radiotherapy.

James B. Mitchell, J. Brender, M. Krishna, 2020, Antioxidants & redox signaling.

Molecular imaging of tumor photoimmunotherapy: Evidence of photosensitized tumor necrosis and hemodynamic changes.

James B. Mitchell, P. Choyke, J. Ardenkjaer-Larsen, 2018, Free radical biology & medicine.

Pharmacologic Ascorbate Induces Transient Hypoxia Sensitizing Pancreatic Ductal Adenocarcinoma to a Hypoxia Activated Prodrug.

J. Brender, S. Kishimoto, Kazu Yamamoto, 2024, Free radical biology & medicine.

Pharmacological Ascorbate Induces Transient Hypoxia Sensitizing Pancreatic Ductal Adenocarcinoma to a Hypoxia Activated Prodrug

J. Brender, S. Kishimoto, Kazu Yamamoto, 2024, bioRxiv.