K. Timm

发表

17: Magnetic resonance imaging of tumour metabolism

K. Brindle, T. Rodrigues, D. Hu, 2014 .

Cancer Therapy-Induced Cardiotoxicity—A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy

K. Timm, Anurag Choksey, 2021, International journal of molecular sciences.

Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics

D. Tyler, J. West, J. Griffin, 2022, Frontiers in Physiology.

Cardiac applications of hyperpolarised magnetic resonance.

D. Tyler, J. Henry, Jack J J Miller, 2018, Progress in nuclear magnetic resonance spectroscopy.

Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response

K. Brindle, K. Timm, B. Kennedy, 2016, Clinical Cancer Research.

Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes

J. Griffin, D. Tyler, L. Heather, 2018, JACC. Basic to translational science.

Nicotinic acid receptor agonists impair myocardial contractility by energy starvation

S. Neubauer, K. Clarke, D. Tyler, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized

D. Tyler, Jack J J Miller, V. Ball, 2019 .

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol

D. Tyler, I. Scott, Jack J J Miller, 2020, JCI insight.

Neutrophils incite and macrophages avert electrical storm after myocardial infarction

P. Ellinor, S. Neubauer, G. Wojtkiewicz, 2022, Nature Cardiovascular Research.

Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR

K. Brindle, D. Tyler, Jack J J Miller, 2020, Magnetic Resonance Materials in Physics, Biology and Medicine.

Hyperpolarized magnetic resonance shows that the anti‐ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post‐ischemic function in the diabetic heart

D. Tyler, L. Heather, V. Ball, 2020, NMR in biomedicine.

13C magnetic resonance spectroscopic imaging of hyperpolarized [1‐13C, U‐2H5] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo

K. Brindle, T. Rodrigues, T. Larkin, 2015, Magnetic resonance in medicine.

AICAR prevents doxorubicin-induced heart failure in rats by ameliorating cardiac atrophy and improving fatty acid oxidation

J. Broxholme, D. Tyler, M. Murphy, 2022, bioRxiv.

The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity

D. Tyler, K. Timm, 2020, Cardiovascular Drugs and Therapy.

Rapid, B1‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

P. Bottomley, D. Tyler, L. Valkovič, 2020, Magnetic Resonance in Medicine.

Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy*

K. Brindle, S. Bohndiek, A. Wright, 2016, The Journal of Biological Chemistry.

13C magnetic resonance spectroscopy measurements with hyperpolarized [1‐13C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo

K. Brindle, S. Lyons, T. Rodrigues, 2015, Magnetic resonance in medicine.

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

J. Griffin, D. Tyler, J. West, 2021, Metabolites.

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

J. Broxholme, D. Tyler, J. West, 2020, Communications Biology.

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

J. Broxholme, J. Griffin, D. Tyler, 2020, Communications biology.

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse

K. Brindle, J. Ardenkjaer-Larsen, T. Rodrigues, 2013, NMR in biomedicine.

Novel Views on Heart Function from Dynamic Hyperpolarized NMR

D. Tyler, A. Lau, K. Timm, 2021 .

Hyperpolarized [U‐2H, U‐13C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells

M. Keller, K. Brindle, M. Ralser, 2015, Magnetic resonance in medicine.

Mechanisms of trastuzumab induced cardiotoxicity – is exercise a potential treatment?

K. Timm, Holden Eaton, 2023, Cardio-Oncology.

Detection of transgene expression using hyperpolarized 13C urea and diffusion‐weighted magnetic resonance spectroscopy

K. Brindle, T. Rodrigues, M. Kettunen, 2015, Magnetic resonance in medicine.

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS

D. Tyler, V. Ball, K. Timm, 2018, NMR in biomedicine.

Hyperpolarized [U‐2H, U‐13C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells

M. Keller, K. Brindle, M. Ralser, 2015, Magnetic resonance in medicine.

AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.

J. Broxholme, L. Heather, V. Ball, 2024, Journal of molecular and cellular cardiology.