B. Maryanoff

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Asymmetric induction in an enammonium-iminium rearrangement. Mechanistic insight via NMR, deuterium labeling, and reaction rate studies. Application to the stereoselective synthesis of pyrroloisoquinoline antidepressants

K. Sorgi, C. Maryanoff, D. McComsey, 1990 .

Medicinal Chemistry: From Targets to Therapies.

P. Wipf, B. Maryanoff, 2019, ACS medicinal chemistry letters.

Structure of the RWJ-51084–bovine pancreatic β-trypsin complex at 1.8 Å

L. DeLucas, M. Carson, D. Chattopadhyay, 1999 .

Urotensin-II receptor modulators as potential drugs.

B. Maryanoff, W. Kinney, 2010, Journal of medicinal chemistry.

Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits.

C. Reynolds, B. Maryanoff, B. Damiano, 2009, Journal of medicinal chemistry.

Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.

H. Almond, Jian Li, B. Maryanoff, 2007, Bioorganic & medicinal chemistry letters.

Additions and Corrections - Stereochemistry of the Wittig Reaction. Effect of Nucleophilic Groups in the Phosphonium Ylide

A. Reitz, B. Maryanoff, B. Duhl-Emswiler, 1985 .

Efficient synthesis of 3-substituted 2-arylindoles via Suzuki coupling reactions on the solid phase

H. Ye, B. Maryanoff, Han-Cheng Zhang, 2001 .

Advances in medicinal chemistry

C. Maryanoff, B. Maryanoff, 1992 .

Thrombin Receptor Modulators: Medicinal Chemistry, Biological Evaluation, and Clinical Application

B. Maryanoff, P. Andrade-Gordon, Cailin Chen, 2009 .

1,2,3,4-Tetrahydroquinoline-containing αvβ3 integrin antagonists with enhanced oral bioavailability

G. Leo, Dana L. Johnson, R. Kawahama, 2004 .

RWJ-58259: a selective antagonist of protease activated receptor-1.

C. Derian, B. Maryanoff, B. Damiano, 2006, Cardiovascular drug reviews.

Aza-bicyclic amino acid carboxamides as α4β1/α4β7 integrin receptor antagonists

B. Maryanoff, C. Schneider, B. Damiano, 2005 .

Stereochemical aspects of phosphorus‐containing cyclohexanes

C. Maryanoff, B. Maryanoff, R. O. Hutchins, 2007 .

Antithrombotic properties of RWJ-50353, a potent and novel thrombin inhibitor.

B. Maryanoff, P. Andrade-Gordon, M. J. Costanzo, 2000, Thrombosis research.

Cyclizations of N-acyliminium ions.

I. Turchi, C. Maryanoff, B. Maryanoff, 2004, Chemical reviews.

Cobalt-Mediated Macrocyclizations. Facile Synthesis of 2-Oxo Pyridinophanes via [2 + 2 + 2] Cycloaddition of α,ω-Diynes and Isocyanates†

B. Maryanoff, L. Bonaga, Han-Cheng Zhang, 2003 .

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.

J. Li, H. Ye, C. Derian, 2004, Bioorganic & medicinal chemistry letters.

Acyclic stereocontrol between remote atom centers via intramolecular and intermolecular stereo-communication

K. Mikami, B. Maryanoff, Han-Cheng Zhang, 2001 .

Discovery and optimization of a novel series of thrombin receptor (par-1) antagonists: potent, selective peptide mimetics based on indole and indazole templates.

C. Derian, A. Pandey, D. McComsey, 2001, Journal of medicinal chemistry.

Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3.

H. Ye, C. Derian, B. Maryanoff, 2007, Bioorganic & medicinal chemistry letters.

In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I[S]

M. Ghadiri, L. Curtiss, L. Leman, 2014, Journal of Lipid Research.

Thrombin receptor (PAR-1) antagonists. Solid-phase synthesis of indole-based peptide mimetics by anchoring to a secondary amide.

C. Derian, D. McComsey, B. Maryanoff, 2001, Bioorganic & medicinal chemistry letters.

Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket.

A. Gibbs, M. Connelly, D. McComsey, 2012, Bioorganic & medicinal chemistry letters.

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.

J. Li, H. Ye, C. Derian, 2004, Bioorganic & medicinal chemistry letters.

The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

A. Reitz, B. Maryanoff, 1989 .

Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonist.

L. Minor, B. Maryanoff, B. Damiano, 2008, European journal of pharmacology.

Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships [Erratum to document cited in CA107(17):154217r]

R. Shank, S. Nortey, D. McComsey, 1988 .

Therapeutic potential of protease-activated receptor-1 antagonists

C. Derian, B. Maryanoff, Han-Cheng Zhang, 2003, Expert opinion on investigational drugs.

Generation of novel, potent urotensin-II receptor antagonists by alkylation-cyclization of isoindolinone C3-carbanions

B. Maryanoff, L. Minor, W. Kinney, 2009 .

Blockade of the Thrombin Receptor Protease-Activated Receptor-1 with a Small-Molecule Antagonist Prevents Thrombus Formation and Vascular Occlusion in Nonhuman Primates

M. D'Andrea, M. Nedelman, C. Derian, 2003, Journal of Pharmacology and Experimental Therapeutics.

Inhibitors of Proteases and Amide Hydrolases that Employ an α‐Ketoheterocycle as a Key Enabling Functionality

B. Maryanoff, M. J. Costanzo, 2008 .

Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins

Dana L. Johnson, B. Tounge, B. Maryanoff, 2004 .

CHARACTERIZATION OF RWJ‐351647, A NOVEL NONPEPTIDE VASOPRESSIN V2 RECEPTOR ANTAGONIST

B. Maryanoff, B. Damiano, L. de Garavilla, 2006, Clinical and experimental pharmacology & physiology.

Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation.

W. Abraham, B. Maryanoff, L. de Garavilla, 2010, American journal of respiratory and critical care medicine.

High-affinity thrombin receptor (PAR-1) ligands: a new generation of indole-based peptide mimetic antagonists with a basic amine at the C-terminus.

C. Derian, D. McComsey, B. Maryanoff, 2003, Bioorganic & medicinal chemistry letters.

Administration of a potent antagonist of protease-activated receptor-1 (PAR-1) attenuates vascular restenosis following balloon angioplasty in rats.

M. D'Andrea, C. Derian, D. McComsey, 2001, The Journal of pharmacology and experimental therapeutics.

Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements.

R. Shank, A. Klinger, D. McComsey, 2006, Journal of medicinal chemistry.

Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists of the thrombin receptor (PAR-1).

D. McComsey, B. Maryanoff, D. Oksenberg, 1999, Bioorganic & medicinal chemistry letters.

Drug discovery and the medicinal chemist.

B. Maryanoff, 2009, Future medicinal chemistry.

Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.

J. Spurlino, C. Page, V. Boswell-Smith, 2008, Bioorganic & medicinal chemistry letters.

Stereochemistry in a medium-sized ring. Highly diastereoselective N-oxidation of a substituted 3-benzazonine. X-ray crystal structure of an unusual complex between an amine N-oxide and saccharin

B. Maryanoff, M. Parvez, R. Olofson, 1990 .

Stereochemistry and conformation of a nitrogen-containing, medium-sized ring: hexahydro-1-phenyl-3-benzazonine derivatives. High 1,4-diastereoselectivity in hydrogenation of an exocyclic alkene

H. Almond, B. Maryanoff, 1986 .

Carbonic anhydrase inhibition. Insight into the characteristics of zonisamide, topiramate, and the sulfamide cognate of topiramate

R. Shank, B. Maryanoff, V. Smith-Swintosky, 2008 .

Examination of Two Independent Kinetic Assays for Determining the Inhibition of Carbonic Anhydrases I and II: Structure–Activity Comparison of Sulfamates and Sulfamides

R. Shank, D. McComsey, B. Maryanoff, 2006, Chemical biology & drug design.

Exploration of Potential Prodrugs of RWJ‐445167, an Oxyguanidine‐based Dual Inhibitor of Thrombin and Factor Xa

Tianbao Lu, M. Player, D. McComsey, 2006, Chemical biology & drug design.

Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents

M. Ghadiri, D. Gordon, L. Leman, 2017, ACS central science.

Deuterated Drug Molecules: Focus on FDA-Approved DeutetrabenazinePublished as part of the Biochemistry series "Biochemistry to Bedside".

B. Maryanoff, S. Dewitt, 2017, Biochemistry.

1.7 Stereochemical Lability in Drug Molecules: Cases Where Chirality May Not Be Critical for Drug Development

B. Maryanoff, M. Greco, 2012 .

Synthesis and biological evaluation of novel pyridazinone-based alpha4 integrin receptor antagonists.

D. Hlasta, B. Maryanoff, C. Schneider, 2006, Journal of medicinal chemistry.

Carba‐nucleosides as Potent Antagonists of the Adenosine 5′‐Diphosphate (ADP) Purinergic Receptor (P2Y12) on Human Platelets

H. Ye, B. Maryanoff, B. Damiano, 2008, ChemMedChem.

Facile substitution of resin-bound indoles via the Mannich reaction

B. Maryanoff, Han-Cheng Zhang, Kimberly K. Brumfield, 1998 .

Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa

B. Maryanoff, B. Damiano, L. de Garavilla, 2010, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Dramatic reversal of diastereoselectivity in an N-acyliminium ion cyclization leading to hexahydropyrrolo[2,1-a]isoquinolines. A case of competing steric interactions

G. Bemis, H. Almond, D. McComsey, 1986 .

Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors.

M. Renzi, C. B. Davis, R. Shank, 1998, Journal of medicinal chemistry.

Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.

S. Savvides, E. Di Cera, H. Almond, 2007, Journal of medicinal chemistry.

DELVING INTO THE WITTIG REACTION-STEREOCHEMISTRY AND MECHANISM. STEREOCHEMICAL IDIOSYNCRASIES AND MECHANISTIC IMPLICATIONS1

A. Reitz, B. Maryanoff, 1986 .

Crystal structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.

J H Matthews, A. Tulinsky, B. Maryanoff, 1996, Biophysical journal.

Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.

B. Maryanoff, M. J. Costanzo, 2008, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors

G. Kuo, B. Maryanoff, W. Murray, 2004 .

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor.

C. Derian, D. McComsey, B. Maryanoff, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.

Robert H. Chen, D. McComsey, B. Maryanoff, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists.

B. Maryanoff, L. de Garavilla, J. Gunnet, 2003, Bioorganic & medicinal chemistry letters.

Synthesis of macrocycles via cobalt-mediated [2 + 2 + 2] cycloadditions.

A. Moretto, G. Leo, H. Ye, 2005, Journal of the American Chemical Society.

Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif.

B. Tomczuk, J. Spurlino, Hui-Sheng Huang, 2008, Bioorganic & medicinal chemistry letters.

′ABNORMAL′ DISPLACEMENT IN THE REACTION OF 2-(N-METHYLPYRROLYL)METHYLTRIMETHYLAMMONIUM SALTS WITH SODIUM CYANIDE

B. Maryanoff, J. Carson, A. Molinari, 1977 .

1,2,4-triazolo[3,4-a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists.

B. Maryanoff, B. Damiano, J. Mitchell, 2001, Bioorganic & medicinal chemistry letters.

Reduction of aromatic nitro compounds with sodium borohydride in dimethyl sulfoxide or sulfolane. Synthesis of azo or azoxy derivatives

B. Maryanoff, D. Lamson, R. O. Hutchins, 1971 .

Highly stereoselective synthesis of substituted hydrindanes related to the antiepileptic drug topiramate

B. Maryanoff, M. Greco, 1992 .

Selective reduction of aliphatic ketones and aldehydes to hydrocarbons with sodium cyanoborohydride and p-toluenesulfonyl hydrazide in dimethylformamide-sulfolane

B. Maryanoff, R. O. Hutchins, Cynthia A. Milewski, 1971 .

Doubly connected phosphorus cations. Diaminophosphenium ions from 2-R-2-phospha-1,3-diazacyclohexanes

B. Maryanoff, R. O. Hutchins, 1972 .

Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif.

B. Tomczuk, J. Spurlino, Tianbao Lu, 2010, Journal of medicinal chemistry.

N‐Vinylpyrrolidin‐2‐One as a 3‐Aminopropyl Carbanion Equivalent in the Synthesis of Substituted 1‐Pyrrolines: 2‐Phenyl‐1‐Pyrroline

K. Sorgi, C. Maryanoff, D. McComsey, 2003 .

Thiabenzenes. Reassessment of their chemical and physical properties

J. Stackhouse, K. Mislow, B. Maryanoff, 1975 .

Thiabenzenes. III. Pyramidal stability at sulfur

J. Stackhouse, K. Mislow, B. Maryanoff, 1974 .

Construction of Indole and Benzofuran Systems on the Solid Phase via Palladium-Mediated Cyclizations1

B. Maryanoff, Han-Cheng Zhang, 1997 .

Synthesis and stereochemistry of 7-phenyl-2-propionanilidobenzo[a]quinolizidine derivatives. Structural probes of fentanyl analgesics.

D. McComsey, B. Maryanoff, J. F. Gardocki, 1981, Journal of medicinal chemistry.

Synthesis of C-arabinofuranosyl compounds. Phosphonate and carboxylate isosteres of d-arabinose 1,5-bisphosphate

D. Liotta, S. Nortey, A. Reitz, 1987 .

Stereoselectivity in the electrophile-promoted cyclizations of a hydroxyolefin derived from arabinose. Synthesis of a phosphonate isostere of β-D-arabinose-1,5-diphosphate

S. Nortey, A. Reitz, B. Maryanoff, 1985 .

Synthesis of phosphates and phosphate isosteres of furanose sugars as potential enzyme inhibitors

S. Nortey, A. Reitz, B. Maryanoff, 1988 .

Stereoselective synthesis and biological activity of .beta.- and .alpha.-D-arabinose 1,5-diphosphate: analogs of a potent metabolic regulator

S. Benkovic, S. Pilkis, A. Reitz, 1984 .

Synthesis of an αvβ3 integrin antagonist intermediate via asymmetric hydrogenation of an α,β-unsaturated ester with BoPhoz-iridium and BoPhoz-rhodium catalysts

C. Teleha, B. Maryanoff, W. Kinney, 2008 .

Pyrroloisoquinoline antidepressants. 3. A focus on serotonin.

R. Shank, S. Nortey, D. McComsey, 1990, Journal of medicinal chemistry.

Stereochemical studies on protonated bridgehead amines. ^1H NMR determination of cis and trans B-C ring-fused structures for salts of hexahydropyrrolo [2,1-a] isoquinolines and related C ring homologs. Capture of unstable ring-fused structures in the solid state

S. L. Mayo, D. McComsey, B. Maryanoff, 1989 .

Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.

R. Shank, S. Nortey, D. McComsey, 1987, Journal of medicinal chemistry.

Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin.

R. Shank, D. McComsey, B. Maryanoff, 1984, Journal of medicinal chemistry.

Additions and Corrections - Stereochemistry of Intramolecular Amidoalkylation Reactions in the Synthesis of Polycyclic Isoquinoline Derivatives.

D. McComsey, B. Maryanoff, B. Duhl-Emswiler, 1983 .

A ONE-STEP SYNTHESIS OF OPTICALLY PURE 1,2-ETHANO BIS SULFOXIDES AND PHOSPHINE OXIDES VIA THE COPPER-PROMOTED OXIDATIVE DIMERIZATION OF CHIRAL SULFINYL AND PHOSPHINYL CARBANIONS

K. Mislow, C. Maryanoff, B. Maryanoff, 1973 .

Synthesis of Trisubstituted Indoles on the Solid Phase via Palladium-Mediated Heteroannulation of Internal Alkynes

B. Maryanoff, Han-Cheng Zhang, Kimberly K. Brumfield, 1997 .

Tautomerism and Physical Properties of Pyrido[1,2-a]benzimidazole (PBI) GABA-A Receptor Ligands

A. Reitz, B. Maryanoff, W. Ho, 2000 .

Potential anxiolytic agents. 2. Improvement of oral efficacy for the pyrido[1,2-a]benzimidazole (PBI) class of GABA-A receptor modulators

R. Shank, D. McComsey, B. Maryanoff, 1996 .

High 1,6 diastereoselectivity in the hydride reduction of an acyclic ketone substrate via bicyclic chelation control

B. D. Harris, C. Maryanoff, B. Maryanoff, 1996 .

Remote acyclic diastereocontol involving a bicyclic metal chelate. High 1,5 asymmetric induction in the hydride reduction of δ-hydroxy ketones

B. Maryanoff, M. J. Costanzo, Han-Cheng Zhang, 1994 .

Stereochemistry of the Wittig reaction. Effect of nucleophilic groups in the phosphonium ylide

A. Reitz, B. Maryanoff, B. Duhl-Emswiler, 1985 .

Potential anxiolytic agents. 3. Novel A-ring modified pyrido[1,2-a]benzimidazoles.

J J McNally, R. Shank, S. Nortey, 1999, Bioorganic & medicinal chemistry letters.

Potent, orally active GPIIb/IIIa antagonists containing a nipecotic acid subunit. Structure-activity studies leading to the discovery of RWJ-53308.

J A Mitchell, D. McComsey, B. Maryanoff, 1999, Journal of medicinal chemistry.

Stereoselectivity of electrophile-promoted cyclizations of .gamma.-hydroxyalkenes. An investigation of carbohydrate-derived and model substrates

D. Liotta, S. Nortey, A. Reitz, 1987 .

Macrocyclic Peptide Inhibitors of Serine Proteases. Convergent Total Synthesis of Cyclotheonamides A and B via a Late-Stage Primary Amine Intermediate. Study of Thrombin Inhibition under Diverse Conditions

K. Nicolaou, B. Maryanoff, Aijun Liu, 1995 .

Topiramate as an Inhibitor of Carbonic Anhydrase Isoenzymes

R. Shank, S. Dodgson, B. Maryanoff, 2000, Epilepsia.

An Overview of the Preclinical Aspects of Topiramate: Pharmacology, Pharmacokinetics, and Mechanism of Action

R. Shank, B. Maryanoff, J. F. Gardocki, 2000, Epilepsia.

Stereoselective synthesis of meso-N,N'-dicarbethoxy-2,4-diaminopentane and meso-2,4-diaminopentane

B. Maryanoff, R. O. Hutchins, 1972 .

The Heck reaction with unprotected allylic amidines and guanidines

D. Wisnoski, B. Maryanoff, W. Kinney, 2002 .

Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.

H. Almond, W. Abraham, B. Maryanoff, 2003, Journal of medicinal chemistry.

Presenting a Special Issue on "Medicinal Chemistry: From Targets to Therapies".

P. Wipf, B. Maryanoff, 2020, ACS medicinal chemistry letters.

Selective reductive displacement of alkyl halides and sulfonate esters with cyanoborohydride reagents in hexamethylphosphoramide

C. Maryanoff, B. Maryanoff, R. O. Hutchins, 1977 .

Oxazoles and Oxazolines in Organic Synthesis

B. Maryanoff, 1987 .

Solid-phase synthesis via N-terminal attachment to the 2-chlorotrityl resin

B. Maryanoff, M. Greco, S. C. Yabut, 1997 .

Optically active phosphine sulphides from phosphine oxides and boron trisulphide

K. Mislow, B. Maryanoff, R. Tang, 1973 .

One-step synthesis of optically pure 1,2-ethanobis(sulfoxides)and phosphine oxides via the copper-promoted oxidative dimerization of chiral sulfinyl and phosphinyl carbanions

K. Mislow, C. Maryanoff, B. Maryanoff, 1973 .

In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.

Patricia Andrade-Gordon, H. Almond, B. Maryanoff, 2005, Journal of medicinal chemistry.

Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.

R. Shank, S. Nortey, A. Reitz, 1995, Journal of medicinal chemistry.

7-fluoroindazoles as potent and selective inhibitors of factor Xa.

Mark R Player, D. Parks, Yu-Kai Lee, 2008, Journal of medicinal chemistry.

Reaction of dimethyl diazomalonate and ethyl 2-diazoacetoacetate with N-methylpyrrole

B. Maryanoff, 1982 .

Carbenoid chemistry. Reaction of pyrrole derivatives with ethyl diazoacetate

B. Maryanoff, 1979 .

Selective deoxygenation of ketones and aldehydes including hindered systems with sodium cyanoborohydride

B. Maryanoff, R. O. Hutchins, Cynthia A. Milewski, 1973 .

Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives.

R. Shank, S. Nortey, B. Maryanoff, 1998, Journal of medicinal chemistry.

5 – Synthesis and Utilization of Compounds with Chiral Silicon Centers

C. Maryanoff, B. Maryanoff, 1984 .

Synthesis and characterization of diethylmethylene diphosphonato metal complexes

B. Maryanoff, N. Karayannis, C. M. Mikulski, 1973 .

Reduction of Alkyl Halides and Tosylates with Sodium Cyanoborohydride in Hexamethylphosphoric Triamide (HMPA): A. 1‐Iododecane to n‐Decane B. 1‐Dodecyl Tosylate to n‐Dodecane

B. Maryanoff, R. O. Hutchins, Cynthia A. Milewski, 2003 .

Bis(trifluoroacetoxy)borane

D. McComsey, B. Maryanoff, 2001 .

Carbohydrate biguanides as potential hypoglycemic agents.

C. Bowden, A. Reitz, B. Maryanoff, 1989, Journal of medicinal chemistry.

Synthesis, resolution, and absolute configuration of novel tricyclic benzodiazepines

K. Sorgi, B. Maryanoff, M. Evangelisto, 2004 .

Topiramate: Preclinical Evaluation of a Structurally Novel Anticonvulsant

C. B. Davis, R. Shank, S. Nortey, 1994, Epilepsia.

Sugar sulfamates for seizure control: discovery and development of topiramate, a structurally unique antiepileptic drug.

B. Maryanoff, 2009, Current topics in medicinal chemistry.

Synthesis of Phosphates and Phosphate Isosteres of Furanose Sugars as Potential Enzyme Inhibitors.

S. Nortey, A. Reitz, B. Maryanoff, 1988 .

Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds.

R. Shank, S. Nortey, B. Maryanoff, 1987, Journal of medicinal chemistry.

The effect of arabinose 1,5-bisphosphate on rat hepatic 6-phosphofructo-1-kinase and fructose-1,6-bisphosphatase.

S. Benkovic, S. Pilkis, J. Pilkis, 1986, Biochemical and biophysical research communications.

Chapter 17. Diabetes Mellitus

B. Maryanoff, C. Rasmussen, G. Tutwiler, 1981 .

Formation of chiral alkoxy dienes in Wittig/Michael reactions of 2,3,5-tri-O-benzyl-D-arabinose

A. Reitz, B. Maryanoff, A. D. Jordan, 1987 .

STEREOSELECTIVE SYNTHESIS AND BIOLOGICAL ACTIVITY OF β- AND α-D-ARABINOSE 1,5-DIPHOSPHATE: ANALOGS OF A POTENT METABOLIC REGULATOR

S. Benkovic, S. Pilkis, A. Reitz, 1985 .

(1,3‐Dioxolan‐2‐ylmethyl)triphenylphosphonium Bromide

D. McComsey, B. Maryanoff, M. Reid, 2006 .

Carbenoid chemistry. Reaction of pyrrole derivatives with ethyl diazoacetate

B. Maryanoff, 1979 .

Facile Dephosphonylation of β-Ketophosphonic Acids: Mechanistic Studies

G. Leo, B. Maryanoff, M. Hawkins, 2006 .

Conformational analysis of phosphorus heterocycles. Proton and phosphorus-31 nuclear magnetic resonance study of N,N'-dimethyl-(2R)-2-phospha-1,3-diazacyclohexanes

B. Maryanoff, J. Albrand, R. O. Hutchins, 1972 .

The Wittig Olefination Reaction and Modifications Involving Phosphoryl-Stabilized Carbanions, Stereochemistry, Mechanism, and Selected Synthetic Aspects

A. Reitz, B. Maryanoff, 1989 .

Observation of cis and trans oxaphosphetanes in the Wittig reaction by high-field phosphorus-31 NMR spectroscopy

A. Reitz, B. Maryanoff, M. Mutter, 1984 .

STEREOCHEMICAL OBSERVATIONS ON THE WITTIG REACTION OF OXIDO PHOSPHONIUM YLIDES WITH ALDEHYDES

A. Reitz, B. Maryanoff, B. Duhl-Emswiler, 1983 .

Trans stereoselectivity in the reaction of (4-carboxybutylidene)triphenylphosphorane with aromatic aldehydes

B. Maryanoff, B. Duhl-Emswiler, 1981 .

Suzuki-Miyaura approach to JNJ-26076713, an orally active tetrahydroquinoline-containing alphaVbeta3/alphaVbeta5 integrin antagonist. enantioselective synthesis and stereochemical studies.

C. Schubert, G. Leo, R. Hansen, 2008, The Journal of organic chemistry.

Correction. Properties of Bis(trifluoroacetoxy)borane as a Reducing Agent of Organic Compounds

S. Nortey, D. McComsey, B. Maryanoff, 1981 .

Borane complexes in trifluoroacetic acid. Reduction of indoles to indolines and generation of bis(trifluoroacetoxy)borane

D. McComsey, B. Maryanoff, 1978 .

Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent

C. Page, W. Abraham, B. Maryanoff, 2006 .

Stereochemistry and mechanism of the Wittig reaction. Diasteromeric reaction intermediates and analysis of the reaction course.

A. Reitz, B. Maryanoff, R. Whittle, 1986, Journal of the American Chemical Society.

Cobalt-mediated cyclotrimerisation of bis-alkynes and cyanamides.

B. Maryanoff, L. Bonaga, Han-Cheng Zhang, 2004, Chemical communications.

Synthesis of Pyridine-Containing Macrocycles by Cobalt-Mediated Trimerization of Triply-Bonded Species

A. Moretto, B. Maryanoff, and Han-Cheng Zhang, 2001 .

Cobalt-Mediated Cyclotrimerization of Bis-alkynes and Cyanamides.

B. Maryanoff, L. Bonaga, Han-Cheng Zhang, 2005 .

Synthesis of Pyridine‐Containing Macrocycles by Cobalt‐Mediated Trimerization of Triply‐Bonded Species.

A. Moretto, B. Maryanoff, Han-Cheng Zhang, 2001 .

Determination of the absolute configuration of a key tricyclic component of a novel vasopressin receptor antagonist by use of vibrational circular dichroism.

Xiaolin Cao, L. Nafie, R. Dukor, 2002, Chirality.

Structural studies on McN-5652-X, a high-affinity ligand for the serotonin transporter in mammalian brain.

Xiaolin Cao, L. Nafie, R. Dukor, 2003, Bioorganic & medicinal chemistry.

Dramatic concentration dependence of stereochemistry in the Wittig reaction. Examination of the lithium salt effect

S. Nortey, A. Reitz, B. Maryanoff, 1986 .

Trans stereoselectivity in the reaction of (4-carboxybutylidene)triphenylphosphorane with aromatic aldehydes

B. Maryanoff, B. Duhl-Emswiler, 1982 .

The Wittig reaction of non-stabilized phosphorus ylides and aromatic aldehydes. Studies on erythro and threo β-hydroxyphosphonium salts and the promotion of stereochemical drift by synergism between diastereomers

A. Reitz, B. Maryanoff, 1985 .

Detailed rate studies on the Wittig reaction of nonstabilized phosphorus ylides via phosphorus-31, proton, carbon-13 NMR spectroscopy. Insight into kinetic vs. thermodynamic control of stereochemistry

H. Almond, A. Reitz, B. Maryanoff, 1985 .

NMR rate study on the Wittig reaction of 2,2-dimethylpropanal and tributylbutylidenephosphorane

H. Almond, A. Reitz, D. W. Graden, 1989 .

Stereochemistry and Mechanism of the Wittig Reaction. Diastereomeric Reaction Intermediates and Analysis of the Reaction Course.

H. Almond, A. Reitz, B. Maryanoff, 1987 .

Resolution and absolute configuration of 1,2,3,5,6,10bβ‐hexahydro‐6α‐phenylpyrrolo[2,1‐α]isoquinoline (McN‐4612‐Z). A problem of determination of the enantiomeric purity for a tertiary amine

D. McComsey, B. Maryanoff, 1985 .

Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates.

Charles H Reynolds, Patricia Andrade-Gordon, C. Reynolds, 2004, Bioorganic & medicinal chemistry letters.

Reversibility of a witting intermediate derived from a triphenylphosphonium ylide and an aliphatic aldehyde

A. Reitz, B. Maryanoff, 1984 .

Synthesis of triazolopyridines as conformationally constrained tertiary amides

B. Maryanoff, E. Lawson, W. Hoekstra, 2000 .

Pyridine-Containing Macrocycles via Cobalt-Mediated [2 + 2 + 2] Cycloadditions of α,ω-Bisalkynes

B. Maryanoff, Han-Cheng Zhang, Han‐Cheng Zhang, 2007 .

Thrombogenic collagen-mimetic peptides: Self-assembly of triple helix-based fibrils driven by hydrophobic interactions

J. G. Vinter, H. Almond, E. Lacy, 2008, Proceedings of the National Academy of Sciences.

J. G. Vinter, G. Leo, B. Tounge, 2007, Journal of the American Chemical Society.

Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design.

H. Almond, B. Maryanoff, L. de Garavilla, 2002, Journal of the American Chemical Society.

Stereochemical considerations in structural comparison of enkephalins and endorphins with exogenous opiate agents.

B. Maryanoff, M. J. Zelesko, 1978, Journal of pharmaceutical sciences.

N-aryl-N'-benzylpiperazines as potential antipsychotic agents.

M. Renzi, M. McDonnell, A. Reitz, 1995, Journal of medicinal chemistry.

Photoactivatable peptides based on BMS-197525: a potent antagonist of the human thrombin receptor (PAR-1).

G. Prestwich, B. Maryanoff, J. Elliott, 1999, Bioorganic & medicinal chemistry letters.

Tritiated photoactivatable analogs of the native human thrombin receptor (PAR-1) agonist peptide, SFLLRN-NH2.

G. Prestwich, C. Derian, B. Maryanoff, 2001, The journal of peptide research : official journal of the American Peptide Society.

Potent thrombin inhibitors that probe the S1 subsite: tripeptide transition state analogues based on a heterocycle-activated carbonyl group.

A. Tulinsky, B. Maryanoff, M. J. Costanzo, 1996, Journal of medicinal chemistry.

Guanosine Derivatives as Immunostimulants. Discovery of Loxoribine

Robert H. Chen, D. Klaubert, A. Reitz, 1994 .

Synthesis and Utilization of Compounds with Chiral Silicon Centers

C. Maryanoff, B. Maryanoff, 1986 .

Non-chair six-membered-ring conformations. Preference for a twist-boat (or skew) structure in α-L-sorbopyranose derivatives

H. Almond, B. Maryanoff, M. J. Costanzo, 1994 .

Anticonvulsant sugar sulfamates. Potent cyclic sulfate and cyclic sulfite analogues of topiramate

B. Maryanoff, M. J. Costanzo, J. Schupsky, 1993 .

Structural and conformational studies of 2-phenyl-1,3,2-diaza- and -dioxaboracycloalkanes

I. Turchi, B. Maryanoff, F. A. Davis, 1972 .

Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform.

R. Shank, D. McComsey, B. Maryanoff, 2005, Journal of medicinal chemistry.

Characterization of a stable carboxylic acid intermediate from 1,3-dipolar cycloaddition of a munchnone with 1,2-dicyanocyclobutene

I. Turchi, C. Maryanoff, B. Maryanoff, 1989 .

Phenotypic Assessment and the Discovery of Topiramate

B. Maryanoff, 2016, ACS medicinal chemistry letters.

2009 Edward E Smissman Award. Pharmaceutical "gold" from neurostabilizing agents: topiramate and successor molecules.

B. Maryanoff, Bruce E Maryanoff, 2009, Journal of medicinal chemistry.

Synthesis of Carba-β-l-Fructopyranose and Carbacyclic Analogs of Topiramate, an Anticonvulsant Agent

A. Reitz, B. Maryanoff, M. H. Parker, 2004 .

Characterization of a Stable Carboxylic Acid Intermediate from 1,3-Dipolar Cycloaddition of a Munchnone with 1,2-Dicyanocyclobutene.

I. Turchi, C. Maryanoff, B. Maryanoff, 1990 .

Iminium ion cyclizations. Highly stereoselective synthesis of substituted tetrahydroisoquinoline derivatives

D. McComsey, B. Maryanoff, 1980 .

Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).

K. Wilcox, H. White, D. Brenneman, 2013, Journal of medicinal chemistry.

Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A.

K C Nicolaou, K. Nicolaou, A. Liu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of Topiramate and Its Metabolites in Plasma and Urine of Healthy Subjects and Patients With Epilepsy by Use of a Novel Liquid Chromatography–Mass Spectrometry Assay

E. Perucca, M. Bialer, M. Britzi, 2003, Therapeutic drug monitoring.

Pharmaceutical “Gold” from Neurostabilizing Agents: Topiramate and Successor Molecules

B. Maryanoff, 2009 .

Molecular Pharmacodynamics, Clinical Therapeutics, and Pharmacokinetics of Topiramate

R. Shank, B. Maryanoff, 2008, CNS neuroscience & therapeutics.

A Comparative Study of the Effect of Carbamazepine and Valproic Acid on the Pharmacokinetics and Metabolic Profile of Topiramate at Steady State in Patients with Epilepsy

E. Perucca, M. Bialer, L. Specchio, 2005, Epilepsia.

Pharmacokinetic and Metabolic Investigation of Topiramate Disposition in Healthy Subjects in the Absence and in the Presence of Enzyme Induction by Carbamazepine

René H Levy, E. Perucca, M. Bialer, 2005, Epilepsia.

Anticonvulsant O-Alkyl Sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)- β-D-fructopyranose Sulfamate (I) and Related Compounds.

R. Shank, S. Nortey, B. Maryanoff, 1987 .

Dosage immunologique de topiramate, analogues et anticorps

K. Sorgi, B. Maryanoff, D. Cawley, 1996 .

Sodium cyanoborohydride in hexamethylphosphoramide. An exceptionally selective reagent system for the reduction of alkyl iodides, bromides, and tosylates

B. Maryanoff, R. O. Hutchins, Cynthia A. Milewski, 1971 .

Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate.

D. Chattopadhyay, B. Maryanoff, R. Recacha, 2002, The Biochemical journal.

Carbonic anhydrase-II inhibition. what are the true enzyme-inhibitory properties of the sulfamide cognate of topiramate?

D. McComsey, B. Maryanoff, M. Todd, 2008, Journal of medicinal chemistry.

Electron ionization mass spectra of novel 2,3:4,5-bis-O-(1-methylethylidene)-β―D-fructopyranose derivatives and related sugar sulfamates

S. Nortey, G. Caldwell, K. Sorgi, 1989 .

Macrocyclic inhibitors of serine proteases

B. Maryanoff, M. Greco, 1997 .

Crystal structure of human carbonic anhydrase II complexed with an anticonvulsant sugar sulphamate

D. Chattopadhyay, B. Maryanoff, R. Recacha, 2022 .

Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

Poshen B. Chen, A. Saghatelian, Jiejun Wu, 2020, Nature Biotechnology.

Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

Poshen B. Chen, A. Saghatelian, Jiejun Wu, 2020, Nature Biotechnology.

Potency variation of small-molecule chymase inhibitors across species.

J. Spurlino, I. Deckman, Shariff S Bayoumy, 2010, Biochemical pharmacology.

A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase

Narayanasami Sukumar, Claudia K Derian, Patricia Andrade-Gordon, 2005, Journal of Biological Chemistry.

Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3.

S. Emanuel, H. Ye, C. Derian, 2003, Bioorganic & medicinal chemistry letters.

Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors.

R. Shank, D. McComsey, B. Maryanoff, 1998, Bioorganic & medicinal chemistry letters.

Preclinical evaluation of McN-5707 as a potential antidepressant.

R. Shank, D. McComsey, B. Maryanoff, 1987, The Journal of pharmacology and experimental therapeutics.

Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.

M. Ghadiri, L. Leman, B. Maryanoff, 2014, Journal of medicinal chemistry.

Thrombin receptor (PAR-1) antagonists. Heterocycle-based peptidomimetics of the SFLLR agonist motif.

D. McComsey, B. Maryanoff, R. Scarborough, 1998, Bioorganic & medicinal chemistry letters.

Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042

B. D. Harris, D. McComsey, B. Maryanoff, 1996 .

Convenient preparation of aryl-substituted nortropanes by SuzukiMiyaura methodology

T. Hudlický, B. Maryanoff, W. Kinney, 2006 .

Heteroaromatic N-oxide rearrangements. Reinvestigation of 1,3 tosyloxy migration in the reaction of isoquinoline N-oxide with tosyl chloride

G. Leo, A. Reitz, B. Maryanoff, 1993 .

Antiplatelet and antithrombotic activity of RWJ-53308, a novel orally active glycoprotein IIb/IIIa antagonist.

B. Maryanoff, B. Damiano, J. Mitchell, 2001, Thrombosis research.

Carbonic anhydrase inhibition. Insight into the characteristics of zonisamide, topiramate, and the sulfamide cognate of topiramate.

R. Shank, B. Maryanoff, V. Smith-Swintosky, 2008, Journal of Enzyme Inhibition and Medicinal Chemistry.

Overview Design and Evaluation of Potent Peptide-Mimetic PAR 1 Antagonists

C. Derian, B. Maryanoff, P. Andrade‐Gordon, 2003 .

Protease-activated receptor-2 (PAR-2): structure-function study of receptor activation by diverse peptides related to tethered-ligand epitopes.

D. McComsey, B. Maryanoff, C. E. Smith, 2001, Archives of biochemistry and biophysics.

Thrombin receptor-activating peptides (TRAPs): investigation of bioactive conformations via structure-activity, spectroscopic, and computational studies.

G. Leo, D. McComsey, B. Maryanoff, 1999, Bioorganic & medicinal chemistry.

Macrocyclic hexapeptide analogues of the thrombin receptor (PAR-1) activation motif SFLLRN.

D. McComsey, B. Maryanoff, L. R. Hecker, 1999, Bioorganic & medicinal chemistry letters.

McN-5652: a highly potent inhibitor of serotonin uptake.

R. Shank, D. McComsey, B. Maryanoff, 1988, The Journal of pharmacology and experimental therapeutics.

Structure of human alpha-thrombin complexed with RWJ-51438 at 1.7 A: unusual perturbation of the 60A-60I insertion loop.

L. DeLucas, M. Carson, D. Chattopadhyay, 2000, Acta crystallographica. Section D, Biological crystallography.

Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs.

M. Ghadiri, T. Imura, L. Curtiss, 2013, Journal of the American Chemical Society.

Cyclotheonamide derivatives: synthesis and thrombin inhibition. Exploration of specific structure-function issues.

B. Maryanoff, M. Greco, J. Kauffman, 1995, Bioorganic & medicinal chemistry.

Structure-function analysis of urotensin II and its use in the construction of a ligand-receptor working model.

Patricia Andrade-Gordon, H. Almond, B. Maryanoff, 2002, Angewandte Chemie.

Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.

L. Leclercq, R. Iannucci, H. White, 2009, Journal of medicinal chemistry.

Remote stereocontrol in acyclic systems. Hydride addition to 1,5- and 1,6-hydroxy ketones mediated by metal chelation

B. Maryanoff, E. Lawson, Han-Cheng Zhang, 1999 .

In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor.

Brian Lord, Leah Aluisio, Pascal Bonaventure, 2008, European journal of pharmacology.

DEALKYLATION OF A TERTIARY AMINE GROUP BY AN INTRAMOLECULAR CARBAMYL CHLORIDE FUNCTIONALITY

C. Maryanoff, D. McComsey, B. Maryanoff, 1983 .

Studies with an Orally Bioavailable αV Integrin Antagonist in Animal Models of Ocular Vasculopathy: Retinal Neovascularization in Mice and Retinal Vascular Permeability in Diabetic Rats

S. Mousa, S. Bursell, A. Clermont, 2008, Journal of Pharmacology and Experimental Therapeutics.

Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR.

Monica A. Chalfant, M. Ghadiri, W. Balch, 2011, ACS medicinal chemistry letters.

The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors.

B. Maryanoff, F. Chrzanowski, B. A. McGrogan, 1985, Journal of Medicinal Chemistry.

THE PKA OF BUTACLAMOL AND THE MODE OF BUTACLAMOL BINDING TO CENTRAL DOPAMINE RECEPTORS

B. Maryanoff, F. Chrzanowski, B. A. McGrogan, 1985 .

A Concise Synthesis of an Indenopyrrolidine-based Dual avb3/avb5 Integrin Antagonist

B. Tounge, B. Maryanoff, B. Damiano, 2004 .

Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif

A. Tulinsky, B. Maryanoff, Joan M. Lewis, 1996 .

A theoretical model of the human thrombin receptor (PAR-1), the first known protease-activated g-protein-coupled receptor

M. P. Beavers, B. Maryanoff, B. Blackhart, 1999 .

Anomalous Stereochemistry in the Wittig Reaction Induced by Nucleophilic Groups in the Phosphonium Ylide

A. Reitz, B. Maryanoff, B. Duhl-Emswiler, 1983 .

Potential affinity labels for the opiate receptor based on fentanyl and related compounds.

E. J. Simon, T. Gioannini, B. Maryanoff, 1982, Journal of medicinal chemistry.

POTENTIAL AFFINITY LABELS FOR THE OPIATE RECEPTOR BASED ON FENTANYL AND RELATED COMPOUNDS

E. J. Simon, T. Gioannini, B. Maryanoff, 1983 .

Conformational analysis of 2-phospha-1,3-dithiacyclohexanes. Further evidence for the general axial preference of phosphorus substituents in saturated six-membered rings

B. Maryanoff, R. O. Hutchins, 1972 .

Phosphorus-containing cyclohexanes. Nuclear magnetic resonance studies and conformational analysis of 1,3,2-dithiaphosphorinanes

A. McPhail, B. Maryanoff, R. O. Hutchins, 1981 .

NMR THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SERINE PROTEASE INHIBITOR CYCLOTHEONAMIDE A

B. Podlogar, G. Leo, G. Caldwell, 1997 .

Transformation of the marine natural product cyclotheonamide A by aqueous base. X-ray analysis of a novel ligand complexed with human α-thrombin

A. Tulinsky, E. Zhang, B. Maryanoff, 1996 .

Unusual Lability of a-Silyloxy -Amino Carboxylic Acid Derivatives.

B. Maryanoff, M. Greco, H. Zhong, 1998 .

Unusual Lability of α‐Silyloxy β‐Amino Carboxylic Acid Derivatives.

B. Maryanoff, M. Greco, H. Zhong, 1998 .

Deoxygenation of Acetylenic Carbinols. Reduction of Cobalt Carbonyl Adducts with Borane-Methyl Sulfide and Trifluoroacetic Acid

A. Reitz, C. Maryanoff, D. McComsey, 1986 .

Substituted pyrrolines useful as kinase inhibitors.

D. McComsey, B. Maryanoff, B. Conway, 2003 .

Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.

J. Spurlino, C. Page, B. Tounge, 2008, Bioorganic & medicinal chemistry letters.

Deuterated Drug Molecules: Focus on FDA-Approved DeutetrabenazinePublished as part of the Biochemistry series "Biochemistry to Bedside".

B. Maryanoff, S. Dewitt, 2017, Biochemistry.

Potency variation of small-molecule chymase inhibitors across species.

J. Spurlino, I. Deckman, Shariff S Bayoumy, 2010, Biochemical pharmacology.

Metabolism and excretion of the antiepileptic/antimigraine drug, topiramate in animals and humans

G. Leo, W. Wu, G. Caldwell, 2005, European Journal of Drug Metabolism and Pharmacokinetics.

Blockade of the Thrombin Receptor Protease-Activated Receptor-1 with a Small-Molecule Antagonist Prevents Thrombus Formation and Vascular Occlusion in Nonhuman Primates

M. D'Andrea, M. Nedelman, C. Derian, 2003, Journal of Pharmacology and Experimental Therapeutics.

Discovery of potent peptide-mimetic antagonists for the human thrombin receptor, protease-activated receptor-1 (PAR-1).

C. Derian, B. Maryanoff, P. Andrade‐Gordon, 2003, Current Medicinal Chemistry - Cardiovascular & Hematological Agents.

Design and evaluation of potent peptide‐mimetic PAR1 antagonists

C. Derian, B. Maryanoff, P. Andrade‐Gordon, 2003 .

In Memoriam: Dr. Paul A. J. Janssen (1926−2003)

B. Maryanoff, F. Janssens, R. Galemmo, 2005 .

Memorial issue in honor of Dr. Paul A. J. Janssen.

P. Lewi, B. Maryanoff, F. Janssens, 2005, Journal of medicinal chemistry.

Structure of the RWJ-51084-bovine pancreatic beta-trypsin complex at 1.8 A.

L. DeLucas, M. Carson, D. Chattopadhyay, 1999, Acta crystallographica. Section D, Biological crystallography.

Adventures in drug discovery: potent agents based on ligands for cell-surface receptors.

B. Maryanoff, 2006, Accounts of Chemical Research.

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.

A. Gibbs, D. McComsey, B. Maryanoff, 2011, ACS medicinal chemistry letters.

Adventures in Drug Discovery: Potent Agents Based on Ligands for Cell-Surface Receptors

B. Maryanoff, 2007 .