J. Moffat

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A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii

L. Tompkins, J. Moffat, 1992, Infection and immunity.

Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.

Dongmei Liu, J. Moffat, R. J. Greenblatt, 2009, Antiviral research.

The latency-associated transcript locus of herpes simplex virus 1 is a virulence determinant in human skin.

A. Davison, Dongmei Liu, J. W. Foley, 2020, PLoS pathogens.

Effects of an isogenic Zn‐metalloprotease‐deficien mutant of Legionella pneumophila in a guinea‐pig pneumonia model

J. Cirillo, L. Tompkins, P. Edelstein, 1994, Molecular microbiology.

Further molecular characterization of the cloned Legionella pneumophila zinc metalloprotease

L. Tompkins, J. Moffat, W. Black, 1994, Infection and immunity.

DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses

Dongmei Liu, J. Moffat, W. Coombs, 2020, Frontiers in Microbiology.

Varicella-zoster virus: aspects of pathogenesis and host response to natural infection and varicella vaccine.

A. Arvin, J. Moffat, R. Redman, 1996, Advances in virus research.

β-L-1-[5-(E-2-Bromovinyl)-2-(Hydroxymethyl)-1,3-Dioxolan-4-yl)] Uracil (L-BHDU) Inhibits Varicella Zoster Virus Replication by Depleting the Cellular dTTP Pool

C. K. Chu, Dongmei Liu, J. Moffat, 2020, bioRxiv.

Attenuation of the Vaccine Oka Strain of Varicella-Zoster Virus and Role of Glycoprotein C in Alphaherpesvirus Virulence Demonstrated in the SCID-hu Mouse

C. Grose, P. Kinchington, A. Arvin, 1998, Journal of Virology.

Differentiation of Varicella-Zoster Virus ORF47 Protein Kinase and IE62 Protein Binding Domains and Their Contributions to Replication in Human Skin Xenografts in the SCID-hu Mouse

C. Bagowski, Hideki Ito, M. Sommer, 2003, Journal of Virology.

Functions of the C-Terminal Domain of Varicella-Zoster Virus Glycoprotein E in Viral Replication In Vitro and Skin and T-Cell Tropism In Vivo

M. Sommer, A. Arvin, J. Moffat, 2004, Journal of Virology.

β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.

C. K. Chu, Dongmei Liu, J. Moffat, 2014, Antiviral research.

HSV-1 remodels host telomeres to facilitate viral replication.

Eui Tae Kim, M. Weitzman, S. Hensley, 2014, Cell reports.

β-L-1-[5-(E-2-Bromovinyl)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)] uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity

D. Depledge, C. K. Chu, Dongmei Liu, 2020, bioRxiv.

in the SCID-hu Mouse C in Alphaherpesvirus Virulence Demonstrated Varicella-Zoster Virus and Role of Glycoprotein Attenuation of the Vaccine Oka Strain of

C. Grose, P. Kinchington, A. Arvin, 1998 .

Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.

C. Grose, C. Hatfield, W. Ruyechan, 2000, Virology.

Varicella-zoster Virus Infection of T cells and Skin in the SCID-hu Mouse Model

A. Arvin, J. Moffat, 1999 .

H84T BanLec has broad spectrum antiviral activity against human herpesviruses in cells, skin, and mice

D. Markovitz, J. Moffat, M. Legendre, 2022, Scientific Reports.

Development of Robust Varicella Zoster Virus Luciferase Reporter Viruses for In Vivo Monitoring of Virus Growth and Its Antiviral Inhibition in Culture, Skin, and Humanized Mice

Dongmei Liu, P. Kinchington, Michael B Yee, 2022, Viruses.

A Novel Human Skin Tissue Model To Study Varicella-Zoster Virus and Human Cytomegalovirus

Dongmei Liu, P. Kinchington, G. Chan, 2020, Journal of Virology.

Genetic Analysis of Varicella-Zoster Virus ORF0 to ORF4 by Use of a Novel Luciferase Bacterial Artificial Chromosome System

Weijia Wang, M. Sommer, A. Arvin, 2007, Journal of Virology.

Varicella-Zoster Virus Infection of Human Fibroblast Cells Activates the c-Jun N-Terminal Kinase Pathway

J. Moffat, Heidi J. Zapata, M. Nakatsugawa, 2006, Journal of Virology.

Human Cytomegalovirus Genes in the 15-Kilobase Region Are Required for Viral Replication in Implanted Human Tissues in SCID Mice

Shannon L. Taylor, S. Smirnov, Weijia Wang, 2005, Journal of Virology.

Varicella-Zoster Virus Infection of Human Foreskin Fibroblast Cells Results in Atypical Cyclin Expression and Cyclin-Dependent Kinase Activity

J. Moffat, Stacey A Leisenfelder, 2006, Journal of Virology.

Roscovitine, a Cyclin-Dependent Kinase Inhibitor, Prevents Replication of Varicella-Zoster Virus

Shannon L. Taylor, A. Brooks, P. Kinchington, 2004, Journal of Virology.

Cyclin-Dependent Kinase 1/Cyclin B1 Phosphorylates Varicella-Zoster Virus IE62 and Is Incorporated into Virions

P. Kinchington, J. Moffat, Stacey A Leisenfelder, 2008, Journal of Virology.

Viral and cellular kinases are potential antiviral targets and have a central role in varicella zoster virus pathogenesis.

Shannon L. Taylor, J. Moffat, Jennifer F Moffat, 2004, Biochimica et biophysica acta.

Viral and cellular kinases play a central role in VZV pathogenesis and are targets for antiviral kinase inhibitors

Shannon L. Taylor, J. Moffat, Stacey A Leisenfelder, 2003 .

The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse.

J. Cohen, J. Cohen, M. Sommer, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu mice

A. Arvin, J. Moffat, H. Kaneshima, 1995, Journal of virology.

Cellular Stress Response to Varicella-Zoster Virus Infection of Human Skin Includes Highly Elevated Interleukin-6 Expression

K. Knudtson, H. Kita, J. Carpenter, 2018, Open forum infectious diseases.

Varicella-zoster virus T cell tropism and the pathogenesis of skin infection.

S. Vleck, X. Che, M. Sommer, 2010, Current topics in microbiology and immunology.

Replication of Varicella-Zoster Virus in Human Skin Organ Culture

Shannon L. Taylor, J. Moffat, 2005, Journal of Virology.

Glycoprotein I of Varicella-Zoster Virus Is Required for Viral Replication in Skin and T Cells

Shannon L. Taylor, Hideki Ito, M. Sommer, 2002, Journal of Virology.

Effects of varicella-zoster virus on cell cycle regulatory pathways.

J. Moffat, R. J. Greenblatt, Rebecca Greenblatt, 2010, Current topics in microbiology and immunology.

Meeting report: 31st International Conference on Antiviral Research

M. Bray, D. Durantel, E. Ballana, 2018, Antiviral Research.

GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1

C. Nomura, Z. Sarwar, J. Moffat, 2016, mSphere.

A Pilot Study: Is Attenuated Varicella Virus Present in Breast Milk After Postpartum Immunization?

J. Moffat, M. Wojtowycz, G. Dolbear, 2003 .

A Human Skin Model for Assessing Arboviral Infections

S. Thangamani, J. Moffat, P. Upadhyaya, 2022, medRxiv.

Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa

T. Mah, C. Nomura, J. Moffat, 2017, Scientific Reports.

Analysis of the functions of glycoproteins E and I and their promoters during VZV replication in vitro and in skin and T-cell xenografts in the SCID mouse model of VZV pathogenesis.

M. Reichelt, B. Berarducci, M. Sommer, 2010, Current topics in microbiology and immunology.

Blocking RpoN reduces virulence of Pseudomonas aeruginosa isolated from cystic fibrosis patients and increases antibiotic sensitivity in a laboratory strain

C. Nomura, J. Moffat, M. Lloyd, 2019, Scientific Reports.

Blocking RpoN reduces virulence of Pseudomonas aeruginosa isolated from cystic fibrosis patients and increases antibiotic sensitivity in a laboratory strain

James L. Vossler, C. Nomura, J. Moffat, 2019, Scientific Reports.

Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa

T. Mah, C. Nomura, J. Moffat, 2017, Scientific Reports.