C. Schalk-Hihi

发表

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

J. Clemente, R. DesJarlais, Robyn Miller, 2011, Protein science : a publication of the Protein Society.

Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.

A. Wlodawer, A. Olson, G. Morris, 1997, Biochemistry.

Purification of receptor complexes of interleukin-10 stoichiometry and the importance of deglycosylation in their crystallization.

A. Wlodawer, D. Hoover, S. Menon, 1999, European journal of biochemistry.

Direct evidence of a heterotrimeric complex of human interleukin‐4 with its receptors

A. Wlodawer, B. Castner, M. Gerhart, 1995 .

Stoichiometry of the complex of human interleukin‐4 with its receptor

A. Wlodawer, B. Castner, C. March, 1994, FEBS letters.

A novel fluorogenic substrate for the measurement of endothelial lipase activity

M. Connelly, I. Deckman, Shariff S Bayoumy, 2011, Journal of Lipid Research.

6-Substituted quinolines as RORγt inverse agonists.

J. Edwards, J. Spurlino, M. Cummings, 2017, Bioorganic & medicinal chemistry letters.

Screening and Characterization of Human Monoglyceride Lipase Active Site Inhibitors Using Orthogonal Binding and Functional Assays

J. Clemente, L. Kuo, D. Maguire, 2012, Journal of biomolecular screening.

Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.

J. Edwards, J. Spurlino, M. Cummings, 2017, Bioorganic & medicinal chemistry letters.

Identification of a Highly Diverged Class ofS-Adenosylmethionine Synthetases in the Archaea*

D. Graham, G. D. Markham, C. Schalk-Hihi, 2000, The Journal of Biological Chemistry.

Protein Engineering of the Colony-stimulating Factor-1 Receptor Kinase Domain for Structural Studies*

B. Grasberger, C. Schubert, I. Deckman, 2006, Journal of Biological Chemistry.

Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors*

Mark R Player, J. Spurlino, R. Patch, 2006, Journal of Biological Chemistry.

Enhancing Recombinant Protein Quality and Yield by Protein Stability Profiling

I. Deckman, C. Schalk-Hihi, W. Chan, 2007, Journal of biomolecular screening.

A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice.

G. Leo, D. Hlasta, H. Xin, 2013, Bioorganic & medicinal chemistry letters.

2-Hydroxy-4,6-diamino-[1,3,5]triazines: a novel class of VEGF-R2 (KDR) tyrosine kinase inhibitors.

R. Patch, M. Player, T. Carver, 2005, Journal of medicinal chemistry.

Crystal structure of human interleukin‐10 at 1.6 Å resolution and a model of a complex with its soluble receptor

A. Wlodawer, C. Schalk-Hihi, A. Zdanov, 1996, Protein science : a publication of the Protein Society.

Protein thermal shifts to identify low molecular weight fragments.

C. Schalk-Hihi, J. Kranz, 2011, Methods in enzymology.

Crystal structure of Epstein-Barr virus protein BCRF1, a homolog of cellular interleukin-10.

S. Menon, A. Wlodawer, S. Menon, 1997, Journal of molecular biology.

Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma.

A Wlodawer, A. Wlodawer, A. Gustchina, 1995, Structure.

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

K. Rhodes, J. Spurlino, L. Kuo, 2017, The Journal of Biological Chemistry.

Structure of the D30N active site mutant of FIV proteinase complexed with a statine-based inhibitor

A. Wlodawer, A. Gustchina, J. Lubkowski, 1997 .

A model of the complex between interleukin‐4 and its receptors

A. Wlodawer, A. Gustchina, A. Zdanov, 1995, Proteins.

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

K. Rhodes, J. Spurlino, L. Kuo, 2017, The Journal of Biological Chemistry.

The conformations of a substrate and a product bound to the active site of S-adenosylmethionine synthetase.

G. D. Markham, C. Schalk-Hihi, 1999, Biochemistry.

INTERLEUKIN-10 CRYSTAL STRUCTURE REVEALS THE FUNCTIONAL DIMER WITH AN UNEXPECTED TOPOLOGICAL SIMILARITY TO INTERFERON GAMMA

A. Wlodawer, A. Gustchina, A. Zdanov, 1995 .

Direct evidence of a heterotrimeric complex of human interleukin‐4 with its receptors

A. Wlodawer, B. Castner, M. Gerhart, 1997, Protein science : a publication of the Protein Society.

Acid-base catalysis in the chemical mechanism of inosine monophosphate dehydrogenase.

G. D. Markham, C. Schalk-Hihi, Cindy L. Bock, 1999, Biochemistry.