Arnaud Machelart

发表

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

C. Locht, G. Salzano, R. Brosch, 2019, ACS nano.

Trypanosoma Infection Favors Brucella Elimination via IL-12/IFNγ-Dependent Pathways

E. Muraille, J. Letesson, G. Vanwalleghem, 2017, Front. Immunol..

Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen

E. Muraille, J. Letesson, Arnaud Machelart, 2017, Infection and Immunity.

Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice

B. Ryffel, E. Muraille, J. Letesson, 2016, The Journal of Immunology.

In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice

B. Ryffel, E. Muraille, J. Letesson, 2015, PloS one.

Brucella melitensis Invades Murine Erythrocytes during Infection

E. Muraille, J. Letesson, J. Vanderwinden, 2014, Infection and Immunity.

In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice

S. Akira, B. Ryffel, R. Copin, 2012, PLoS pathogens.

Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

Ravikumar Jimmidi, E. Muraille, E. Biondi, 2019, Nature Communications.

Host-directed therapies offer novel opportunities for the fight against tuberculosis.

P. Brodin, Ok-Ryul Song, Arnaud Machelart, 2017, Drug discovery today.

Proteomics of Mycobacterium Infection: Moving towards a Better Understanding of Pathogen-Driven Immunomodulation

P. Brodin, Ok-Ryul Song, Arnaud Machelart, 2018, Front. Immunol..

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

L. Johannes, Serena Petracchini, J. Cintrat, 2022, iScience.

Fragment-based optimized EthR inhibitors with in vivo ethionamide boosting activity.

R. Wintjens, Xue Li, A. Baulard, 2020, ACS infectious diseases.

Alteration of the gut microbiota’s composition and metabolic output correlates with COVID-19-like severity in obese NASH hamsters

H. Sokol, N. Benech, T. Sulpice, 2022, Gut microbes.

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice

J. Wouters, E. Muraille, V. Flamand, 2021, PLoS pathogens.

Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies

M. Chamaillard, P. Brodin, Arnaud Machelart, 2020, Frontiers in Immunology.

An original methodology to study polymeric nanoparticle-macrophage interactions: nanoparticle tracking analysis in cell culture media and quantification of the internalized objects.

R. Gref, P. Brodin, Arnaud Machelart, 2021, International journal of pharmaceutics.

IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection

R. Beyaert, L. Majlessi, P. Brodin, 2019 .

IRG1 controls host responses to restrict Mycobacterium tuberculosis infection

E. Muraille, R. Beyaert, L. Majlessi, 2022, bioRxiv.

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation.

Xue Li, A. Baulard, R. Gref, 2019, Organic & biomolecular chemistry.

High-Content Analysis Monitoring Intracellular Trafficking and Replication of Mycobacterium tuberculosis Inside Host Cells.

P. Brodin, Arnaud Machelart, Eik Hoffmann, 2021, Methods in molecular biology.

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters

Virgile Richard, F. Pinet, T. Sulpice, 2022, Viruses.

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Ruxandra Gref, Benoit Deprez, Catherine Piveteau, 2017, Scientific Reports.

Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway

C. Wittmann, J. Letesson, I. Moriyón, 2020, Proceedings of the National Academy of Sciences.

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

J. Dubuisson, D. Hober, S. Belouzard, 2021, bioRxiv.

Large scale screening discovers clofoctol as an inhibitor of SARS-CoV-2 replication that reduces COVID-19-like pathology

J. Dubuisson, D. Hober, S. Belouzard, 2021 .

Erythritol Availability in Bovine, Murine and Human Models Highlights a Potential Role for the Host Aldose Reductase during Brucella Infection

E. Muraille, J. Letesson, I. Moriyón, 2017, Front. Microbiol..

Route of Infection Strongly Impacts the Host-Pathogen Relationship

E. Muraille, J. Letesson, J. Vanderwinden, 2019, Front. Immunol..

Allergic Asthma Favors Brucella Growth in the Lungs of Infected Mice

E. Muraille, J. Letesson, J. Vanderwinden, 2018, Front. Immunol..

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Virgile Richard, J. Dubuisson, H. Sokol, 2021, Gut microbes.

SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota

H. Sokol, V. Contreras, S. van der Werf, 2021, Gut microbes.

Tirap controls Mycobacterium tuberculosis phagosomal acidification

M. Chamaillard, Y. Rouillé, L. Majlessi, 2023, PLoS pathogens.

A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2

L. Johannes, Serena Petracchini, J. Cintrat, 2021, bioRxiv.

Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.

Souvik Sarkar, C. Stallings, T. Tønjum, 2023, Journal of Medicinal Chemistry.

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters

D. Bernard, T. Idziorek, S. Belouzard, 2023, Nature Aging.

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

J. Dubuisson, D. Hober, S. Belouzard, 2022, PLoS pathogens.

Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen

E. Muraille, J. Letesson, Arnaud Machelart, 2017, Infection and Immunity.