Pui Yee Ng

发表

Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.

Jared T. Shaw, Jared T Shaw, H. Stadler, 2007, Angewandte Chemie.

Divergent structural complexity from a linear reaction sequence: synthesis of fused and spirobicyclic gamma-lactams from common synthetic precursors.

Jared T. Shaw, Jared T Shaw, C. Masse, 2006, Journal of combinatorial chemistry.

Cycloaddition reactions of imines with 3-thiosuccinic anhydrides: synthesis of the tricyclic core of martinellic acid.

Jared T. Shaw, C. Masse, Pui Yee Ng, 2006, Organic letters.

Cycloaddition Reactions of Imines with 3‐Thiosuccinic Anhydrides: Synthesis of the Tricyclic Core of Martinellic Acid.

Jared T. Shaw, C. Masse, Pui Yee Ng, 2007 .

The Identification of the SIRT1 Activator SRT2104 as a Clinical Candidate

Amy V. Lynch, David P. Carney, P. J. Elliot, 2013 .

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Amy V. Lynch, David P. Carney, D. Gagne, 2007, Nature.

Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.

Amy V. Lynch, David P. Carney, D. Gagne, 2009, Journal of medicinal chemistry.

Strained silacycles in organic synthesis: a new reagent for the enantioselective allylation of aldehydes.

Pui Yee Ng, Xiaolun Wang, J. L. Leighton, 2002, Journal of the American Chemical Society.

The enantioselective allylation and crotylation of sterically hindered and functionalized aryl ketones: convenient access to unusual tertiary carbinol structures.

Pui Yee Ng, J. L. Leighton, N. Burns, 2006, Angewandte Chemie.

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

Dudley Lamming, D. Sinclair, K. Howitz, 2013, Science.

HDAC11 Deficiency or Inhibition Disrupts Oncogene-Induced Stress Hematopoiesis in Myeloproliferative Neoplasms.

R. Levine, A. Verma, K. Wright, 2019, Blood.

SIRT1 modulation as a novel approach to the treatment of diseases of aging.

J. Ellis, R. Stein, R. Perni, 2011, Journal of medicinal chemistry.

Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.

Xiaozhang Zheng, Bingsong Han, Pui Yee Ng, 2018, Bioorganic & medicinal chemistry letters.

Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators.

Amy V. Lynch, David P. Carney, Siva Lavu, 2009, Bioorganic & medicinal chemistry letters.

Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.

Amy V. Lynch, David P. Carney, D. Gagne, 2009, Journal of medicinal chemistry.

Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.

H. Stadler, Pui Yee Ng, Yuchen Tang, 2007, Angewandte Chemie.