G. Hill

发表

Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Peter Ballard, Simon J Brown, Nathaniel G. Martin, 2014, Journal of medicinal chemistry.

Novel inhibitors of prolyl 4-hydroxylase. 3. Inhibition by the substrate analogue N-oxaloglycine and its derivatives.

C. Cunliffe, G. Hill, T. Franklin, 1992, Journal of medicinal chemistry.

Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase.

N. Keen, S. Wedge, S. Heaton, 2007, Journal of medicinal chemistry.

Approaches to the design of anti-fibrotic drugs.

C. Cunliffe, G. Hill, D. Johnstone, 1991, Biochemical Society transactions.

Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: selective inhibitors of Aurora B kinase with potent anti-tumor activity.

N. Keen, S. Wedge, S. Heaton, 2008, Bioorganic & Medicinal Chemistry Letters.

Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.

Rajesh Odedra, Stephen Green, Nicola Heron, 2006, Journal of medicinal chemistry.

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.

J. Breed, R. Pauptit, S. Green, 2006, Bioorganic & medicinal chemistry letters.

Reaction workup planning: A structured flowchart approach, exemplified in difficult aqueous workup of hydrophilic products

George B. Hill, Joseph B. Sweeney, G. Hill, 2015 .

Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR).

Matthew Grist, M Raymond V Finlay, Richard A Ward, 2013, Journal of medicinal chemistry.

Tricyclic triarylethylene antiestrogens: dibenz[b,f]oxepins, dibenzo[b,f]thiepins, dibenzo[a,e]cyclooctenes, and dibenzo[b,f]thiocins.

G. Hill, D. Acton, B. S. Tait, 1983, Journal of medicinal chemistry.

Two New Syntheses of a 4-Aminopyrazole: Condensation of an N-Substituted Vinamidinium Salt with a Functionalized Hydrazine

A. Mortlock, G. Hill, 2007 .