M. Allarà

发表

2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents.

V. Andrisano, F. Belluti, A. Bisi, 2012, European journal of medicinal chemistry.

Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).

Vincenzo Di Marzo, V. Di Marzo, L. De Petrocellis, 2011, Journal of natural products.

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

Zhanmin Lin, Thomas Hankemeier, Benjamin F. Cravatt, 2017, Science.

Prostamide F2α receptor antagonism combined with inhibition of FAAH may block the pro‐inflammatory mediators formed following selective FAAH inhibition

V. Di Marzo, A. Ligresti, M. Allarà, 2014, British journal of pharmacology.

Arylboronic acids as dual-action FAAH and TRPV1 ligands.

V. Di Marzo, G. Ortar, L. De Petrocellis, 2016, Bioorganic & medicinal chemistry letters.

Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels.

V. Di Marzo, G. Ortar, L. De Petrocellis, 2013, Bioorganic & medicinal chemistry letters.

The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG

T. Bisogno, F. Piscitelli, V. Di Marzo, 2013, Cell Death and Disease.

Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality.

A. Abadi, V. Di Marzo, K. Abouzid, 2016, European journal of medicinal chemistry.

Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop.

O. Carnevali, A. Martella, C. Silvestri, 2016, Endocrinology.

Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands.

Amr H. Mahmoud, A. Abadi, V. Di Marzo, 2010, Bioorganic & medicinal chemistry.

Endocrine disruptors in the diet of male Sparus aurata: Modulation of the endocannabinoid system at the hepatic and central level by Di-isononyl phthalate and Bisphenol A.

O. Carnevali, J. Pérez‐Sánchez, F. Piscitelli, 2018, Environment international.

Synthesis and Pharmacological Activity of a Potent Inhibitor of the Biosynthesis of the Endocannabinoid 2‐Arachidonoylglycerol

T. Bisogno, J. Burston, R. Razdan, 2009, ChemMedChem.

Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach.

R. Vitale, P. Amodeo, V. Di Marzo, 2019, Biochimica et biophysica acta. General subjects.

Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB₁ receptor ligand.

V. Di Marzo, A. Ligresti, Rosaria Villano, 2012, Pharmacological research.

Endocannabinoid Tone Regulates Human Sebocyte Biology.

C. Zouboulis, T. Bíró, J. Gertsch, 2018, The Journal of investigative dermatology.

Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis

S. Petrosino, V. Di Marzo, T. Iuvone, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

V. Di Marzo, M. Torres, P. Iturriaga-Vásquez, 2016, European journal of medicinal chemistry.

1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands.

E. Novellino, R. Silvestri, G. La Regina, 2011, European journal of medicinal chemistry.

A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2‐arachidonoylglycerol with potential anti‐obesity effects

J. Chang, B. Cravatt, A. Lichtman, 2013, British journal of pharmacology.

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility.

M. Mor, V. Di Marzo, S. Lamponi, 2016, Journal of medicinal chemistry.

A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator

E. Pagano, S. Petrosino, A. Izzo, 2021, Cells.

Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes

A. Abadi, V. Di Marzo, K. Abouzid, 2013, Journal of enzyme inhibition and medicinal chemistry.

Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats.

R. Capasso, A. Martella, F. Piscitelli, 2013, Prostaglandins, leukotrienes, and essential fatty acids.

Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

T. Bisogno, S. Petrosino, V. Di Marzo, 2011, British journal of pharmacology.

Anti-inflammatory properties of cannabidiol, a non-psychotropic cannabinoid, in experimental allergic contact dermatitis

S. Petrosino, T. Iuvone, M. Allarà, 2018 .

N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation

F. Spyrakis, B. Rolando, E. Gianquinto, 2022, Molecules.

Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis.

S. Petrosino, V. Di Marzo, M. Allarà, 2016, Veterinary journal.

Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands.

E. Novellino, A. Lavecchia, R. Silvestri, 2010, European journal of medicinal chemistry.

Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.

M. Cascio, A. Minassi, G. Appendino, 2009, Journal of medicinal chemistry.

Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile.

E. Novellino, A. Lavecchia, R. Silvestri, 2009, Bioorganic & medicinal chemistry.

Mooreamide A: A Cannabinomimetic Lipid from the Marine Cyanobacterium Moorea bouillonii

W. Gerwick, V. Marzo, M. Allarà, 2014, Lipids.

Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activi

M. Frosini, G. Valacchi, V. Di Marzo, 2016, ACS chemical neuroscience.

Dose‐Specific Effects of Di‐Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish

O. Carnevali, H. Habibi, F. Piscitelli, 2017, Endocrinology.

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

S. Petrosino, V. Di Marzo, A. Ligresti, 2019, Journal of Neuroinflammation.

Some physico-chemical and microbiological characterist.ics of goats milk produced in Quisiro

M. Allarà, G. Ríos, Y. Olivares, 1999 .

Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain

Simone Brogi, M. Brindisi, S. Gemma, 2018, ChemMedChem.

Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: definition of the structural determinants for enzyme inhibition

E. Novellino, V. Marzo, Simone Brogi, 2016 .

Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands.

Ettore Novellino, Luciana Marinelli, Marco Macchia, 2015, European journal of medicinal chemistry.

Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain.

S. Cuzzocrea, E. Esposito, S. Petrosino, 2015, Pharmacological research.

New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators

F. Belluti, A. Bisi, S. Gobbi, 2021, Molecules.

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons.

P. Chameau, H. Overkleeft, T. Hankemeier, 2015, Journal of the American Chemical Society.

CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides

Brandie M. Ehrmann, V. Di Marzo, A. Ligresti, 2014, Journal of medicinal chemistry.

Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.

Luciano Milanesi, Anna Marabotti, Pasqualina D'Ursi, 2011, European journal of medicinal chemistry.

Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6.

R. McGuire, H. Overkleeft, T. van der Wel, 2014, Journal of medicinal chemistry.

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain.

R. McGuire, H. Overkleeft, G. A. van der Marel, 2013, Angewandte Chemie.

First Evidence of the Protective Effects of 2-Pentadecyl-2-Oxazoline (PEA-OXA) in In Vitro Models of Acute Lung Injury

S. Petrosino, V. Di Marzo, M. Allarà, 2022, Biomolecules.

New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists.

M. Cascio, C. Ghelardini, T. Tuccinardi, 2007, Bioorganic & medicinal chemistry letters.

Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligands

Amr H. Mahmoud, A. Abadi, V. Marzo, 2014 .

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

S. Cuzzocrea, E. Esposito, S. Petrosino, 2017, Front. Pharmacol..

Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.

E. Novellino, A. Coluccia, R. Silvestri, 2012, Journal of medicinal chemistry.

FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug.

R. Vitale, P. Amodeo, G. Marino, 2018, ACS chemical neuroscience.

1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor.

A. Malfitano, V. Di Marzo, A. Ligresti, 2014, European journal of medicinal chemistry.

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

S. Petrosino, V. Di Marzo, A. Ligresti, 2019, Journal of Neuroinflammation.

Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor

M. Mor, A. Ligresti, F. Corelli, 2023, Molecules.

Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6.

R. McGuire, H. Overkleeft, T. van der Wel, 2014, Journal of medicinal chemistry.

Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.

M. Cascio, G. Appendino, V. Di Marzo, 2009, Journal of Medicinal Chemistry.

Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities.

F. Belluti, A. Bisi, S. Gobbi, 2019, ACS medicinal chemistry letters.

Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone.

A. Bertamino, I. Gomez-Monterrey, E. Sommella, 2024, European journal of medicinal chemistry.

Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization.

S. Gemma, G. Campiani, S. Butini, 2024, Journal of medicinal chemistry.